mecamylamine and phenoxybenzamine

mecamylamine has been researched along with phenoxybenzamine in 30 studies

Research

Studies (30)

TimeframeStudies, this research(%)All Research%
pre-199024 (80.00)18.7374
1990's2 (6.67)18.2507
2000's1 (3.33)29.6817
2010's3 (10.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Gnodde, HP; Schuiling, GA1
Gala, RR; Lawson, DM1
Kaplan, PE; Nanninga, JB1
Drawbaugh, RB; Lal, H1
György, L; Phan, DV1
Lederis, K; Medaković, M1
Delbarre, B; Schmitt, H1
Grove, DJ; Nilsson, S1
Garan, H; Hamlin, NP; Powell, WJ; Willerson, JT1
Burka, B; Herman, E; Vick, J1
Farmar, RM; Herman, EH; Schein, P1
Davis, RA1
Rosenblum, G; Rosenblum, I1
Concha, G; González, E; Novakovic, L; Penna, M1
Deavers, S; Huggins, RA; Smith, EL1
Dean, RR; Waterbury, LD1
Arnaiz, JM; García, AG; Horga, JF; Pascual, R; Sánchez-García, P1
Ibi, A; Matsumoto, S; Nagao, T; Nakajima, T2
Martini, L; Motta, M; Piva, F1
Farzin, D; Zarrindast, MR1
Franco, AC; Prado, WA1
Antunes-Rodrigues, J; Corrêa, FM; Crippa, GE; Fernandes, KB; Tavares, RF1
BROWNLEE, G; JOHNSON, ES1
PARDO, EG; VARGAS, R; VIDRIO, H1
PARDO, EG; VIDRIO, H1
BOYD, H; BURNSTOCK, G; ROGERS, D1
Dias, QM; Fais, RS; Petronilho, A; Prado, WA; Reis, GM1

Reviews

1 review(s) available for mecamylamine and phenoxybenzamine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

29 other study(ies) available for mecamylamine and phenoxybenzamine

ArticleYear
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
Involvement of catecholaminergic and cholinergic mechanisms in the pulsatile release of LH in the long-term ovariectomized rat.
    Neuroendocrinology, 1976, Volume: 20, Issue:3

    Topics: Animals; Apomorphine; Bis(4-Methyl-1-Homopiperazinylthiocarbonyl)disulfide; Catecholamines; Circadian Rhythm; Female; Luteinizing Hormone; Mecamylamine; Methyltyrosines; Neurotransmitter Agents; Ovary; Phenoxybenzamine; Pituitary Gland; Pituitary Gland, Anterior; Pyrrolidinones; Rats; Scopolamine

1976
The influence of adrenergic, dopaminergic, cholinergic and serotoninergic drugs on plasma prolactin levels in ovariectomized, estrogen-treated rats.
    Endocrinology, 1975, Volume: 96, Issue:2

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Apomorphine; Arecoline; Atropine; Castration; Clonidine; Dibenzothiepins; Dopamine; Estradiol; Female; Isoproterenol; Mecamylamine; Nicotine; Parasympathomimetics; Phenoxybenzamine; Phentolamine; Pimozide; Piperazines; Prolactin; Rats; Serotonin; Serotonin Antagonists; Stimulation, Chemical; Sulfides

1975
Reduction of bladder contractility after alpha-adrenergic blockade and after ganglionic blockade.
    Acta neurologica Scandinavica, 1979, Volume: 59, Issue:4

    Topics: Adult; Atropine; Ganglia, Autonomic; Humans; Male; Mecamylamine; Muscle Contraction; Muscle, Smooth; Phenoxybenzamine; Pressure; Spinal Cord Injuries; Urethra; Urinary Bladder; Urinary Bladder, Neurogenic

1979
Effect of pharmacological interference with various neuropathways on blockade of morphine-withdrawal hypothermia by morphine and by conditional stimulus.
    Neuropharmacology, 1976, Volume: 15, Issue:6

    Topics: Animals; Benztropine; Conditioning, Classical; Cyproheptadine; Haloperidol; Humans; Hypothermia; Male; Mecamylamine; Morphine Dependence; Nervous System; Phenoxybenzamine; Propranolol; Rats; Substance Withdrawal Syndrome

1976
The pressor effect of oxotremorine and arecoline in rats.
    Acta physiologica Academiae Scientiarum Hungaricae, 1973, Volume: 43, Issue:1

    Topics: Adrenalectomy; Adrenergic alpha-Antagonists; Animals; Arecoline; Atropine; Blood Pressure; Cerebral Ventricles; Cordotomy; Female; Ganglionic Blockers; Hexamethonium Compounds; Male; Mecamylamine; Morphine; Oxotremorine; Phenoxybenzamine; Phentolamine; Rats; Reserpine; Vagotomy

1973
Pharmacological observations on the hypotensive action of extracts of teleost fish Urophyses (urotensin I) in the rat.
    British journal of pharmacology, 1974, Volume: 51, Issue:3

    Topics: Acetylcholine; Angiotensin II; Animals; Atropine; Blood Pressure; Bradykinin; Diphenhydramine; Epinephrine; Female; Fishes; Heart Rate; Hexamethonium Compounds; Hypotension; Injections, Intramuscular; Injections, Intravenous; Injections, Subcutaneous; Male; Mecamylamine; Nicotine; Norepinephrine; Peptides; Perfusion; Phenoxybenzamine; Propranolol; Rats; Time Factors; Tissue Extracts

1974
Sedative effects of alpha-sympathomimetic drugs and their antagonism by adrenergic and cholinergic blocking drugs.
    European journal of pharmacology, 1971, Volume: 13, Issue:3

    Topics: Adrenergic alpha-Antagonists; Animals; Atropine; Behavior, Animal; Chickens; Chloral Hydrate; Dibenzylchlorethamine; Female; Hypnotics and Sedatives; Mecamylamine; Mice; Naphazoline; Phenoxybenzamine; Phentolamine; Sympatholytics; Sympathomimetics; Tolazoline

1971
Adrenergic and cholinergic innervation of the spleen of the cod: Gadus morhua.
    European journal of pharmacology, 1974, Volume: 28, Issue:1

    Topics: Acetylcholine; Animals; Atropine; Dose-Response Relationship, Drug; Electric Stimulation; Epinephrine; Fishes; Hexamethonium Compounds; Histocytochemistry; Isoproterenol; Mecamylamine; Muscle Contraction; Norepinephrine; Parasympathetic Nervous System; Perfusion; Phenoxybenzamine; Phentolamine; Phenylephrine; Splanchnic Nerves; Spleen; Sympathetic Nervous System; Tritium; Yohimbine

1974
The neurogenic vasoconstrictor effect of digitalis on coronary vascular resistance.
    The Journal of clinical investigation, 1974, Volume: 53, Issue:1

    Topics: Blood Pressure; Chloralose; Coronary Vessels; Digitalis Glycosides; Digoxin; Heart Rate; Mecamylamine; Myocardium; Oxygen Consumption; Phenoxybenzamine; Time Factors; Urethane; Vascular Resistance

1974
Role of the sympathetic nervous system in daunomycin-induced arrhythmia in the monkey.
    British journal of pharmacology, 1970, Volume: 39, Issue:3

    Topics: Adrenalectomy; Animals; Arrhythmias, Cardiac; Cordotomy; Daunorubicin; Electrocardiography; Guanethidine; Haplorhini; Hexamethonium Compounds; Male; Mecamylamine; Pargyline; Phenoxybenzamine; Propranolol; Reserpine; Splanchnic Nerves; Stellate Ganglion; Sympathectomy; Sympathetic Nervous System; Vagotomy

1970
Influence of pharmacologic or physiologic pretreatment on acute daunomycin cardiac toxicity in the hamster.
    Toxicology and applied pharmacology, 1970, Volume: 16, Issue:2

    Topics: Animals; Arrhythmias, Cardiac; Atropine; Blood Pressure; Central Nervous System; Cordotomy; Cricetinae; Daunorubicin; Electrocardiography; Epinephrine; Guanethidine; Heart; Heart Rate; Hexamethonium Compounds; Male; Mecamylamine; Norepinephrine; Phenoxybenzamine; Propranolol; Reserpine; Vagotomy; Vagus Nerve

1970
Induction of fatal hypothermia in house-mice.
    The Annals of applied biology, 1968, Volume: 61, Issue:2

    Topics: Animals; Body Temperature; Chlorpromazine; Hydralazine; Hypothermia; Mecamylamine; Methyldopa; Mice; Nialamide; Phenoxybenzamine; Pyrimidines; Sulfonamides

1968
Cardiovascular responses to cyclohexylamine.
    Toxicology and applied pharmacology, 1968, Volume: 12, Issue:2

    Topics: Amines; Animals; Blood Pressure; Bradycardia; Cardiovascular System; Cats; Cocaine; Cyclohexanes; Female; Heart; Heart Rate; Hypertension; Iproniazid; Male; Mecamylamine; Norepinephrine; Phenoxybenzamine; Propranolol; Reserpine; Sensory Receptor Cells; Sweetening Agents; Sympathetic Nervous System; Tachycardia; Tachyphylaxis

1968
[Influence of autonomic drugs on the heart rhythmicity of the isolated guinea pig heart].
    Archivos de biologia y medicina experimentales, 1968, Volume: 5, Issue:3

    Topics: Acetylcholine; Animals; Autonomic Agents; Bradykinin; Female; Guinea Pigs; Heart Rate; Hexamethonium Compounds; Male; Mecamylamine; Nicotine; Phenoxybenzamine; Propranolol; Reserpine; Serotonin; Tyramine

1968
Effects of vasoactive drugs on distribution of blood in the dog.
    Archives internationales de pharmacodynamie et de therapie, 1967, Volume: 165, Issue:2

    Topics: Animals; Atropine; Blood Pressure; Blood Proteins; Blood Volume; Diphenhydramine; Dogs; Epinephrine; Erythrocytes; Hematocrit; Mecamylamine; Norepinephrine; Phenoxybenzamine; Splenectomy

1967
Effects of alpha agonists and alpha blocking drugs on mouse plasma renin activity.
    Proceedings of the Western Pharmacology Society, 1980, Volume: 23

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Dose-Response Relationship, Drug; Drug Interactions; Heart Rate; Indoramin; Isoproterenol; Male; Mecamylamine; Methoxamine; Mice; Phenoxybenzamine; Prazosin; Renin

1980
Origin of guinea-pig plasma dopamine beta-hydroxylase.
    British journal of pharmacology, 1980, Volume: 69, Issue:1

    Topics: Adrenalectomy; Animals; Carbon Dioxide; Dopamine beta-Hydroxylase; Guanethidine; Guinea Pigs; Hydroxydopamines; Mecamylamine; Norepinephrine; Phenoxybenzamine; Time Factors

1980
Effects of carotid body chemoreceptor stimulation by norepinephrine, epinephrine and tyramine on ventilation in the rabbit.
    Archives internationales de pharmacodynamie et de therapie, 1981, Volume: 252, Issue:1

    Topics: Animals; Carotid Body; Chemoreceptor Cells; Epinephrine; Female; Haloperidol; Male; Mecamylamine; Norepinephrine; Phenoxybenzamine; Rabbits; Respiration; Stimulation, Chemical; Tyramine

1981
A pharmacological analysis of the role of the amygdala in the control of gonadotropin and prolactin secretion.
    Advances in biochemical psychopharmacology, 1980, Volume: 24

    Topics: Amygdala; Animals; Atropine; Castration; Female; Gonadotropins, Pituitary; Mecamylamine; Parasympatholytics; Phenoxybenzamine; Pimozide; Prolactin; Propranolol; Rats; Sympatholytics

1980
Effects of carotid body chemoreceptor stimulation by dopamine on ventilation.
    Archives internationales de pharmacodynamie et de therapie, 1980, Volume: 245, Issue:1

    Topics: Adenosine Triphosphate; Animals; Atropine; Carotid Body; Chemoreceptor Cells; Dopamine; Female; Haloperidol; Male; Mecamylamine; Norepinephrine; Phenoxybenzamine; Rabbits; Reflex; Respiration; Stimulation, Chemical

1980
Nicotine attenuates naloxone-induced jumping behaviour in morphine-dependent mice.
    European journal of pharmacology, 1996, Feb-29, Volume: 298, Issue:1

    Topics: Animals; Atropine; Behavior, Animal; Benzazepines; Hexamethonium; Male; Mecamylamine; Mice; Morphine Dependence; Naloxone; Narcotic Antagonists; Nicotine; Phenoxybenzamine; Propranolol; Substance P; Substance Withdrawal Syndrome; Sulpiride

1996
Antinociceptive effects of stimulation of discrete sites in the rat hypothalamus: evidence for the participation of the lateral hypothalamus area in descending pain suppression mechanisms.
    Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 1996, Volume: 29, Issue:11

    Topics: Adrenergic alpha-Antagonists; Analgesia; Analgesics, Opioid; Animals; Atropine; Dopamine Antagonists; Electric Stimulation; Haloperidol; Hypothalamic Area, Lateral; Male; Mecamylamine; Methysergide; Morphine; Muscarinic Antagonists; Naloxone; Narcotic Antagonists; Nicotinic Antagonists; Pain; Phenoxybenzamine; Rats; Rats, Wistar; Serotonin Antagonists

1996
Mechanisms involved in the pressor response to noradrenaline injection into the cingulate cortex of unanesthetized rats.
    Neuropharmacology, 2003, Volume: 44, Issue:6

    Topics: Adrenergic alpha-Antagonists; Animals; Antidiuretic Hormone Receptor Antagonists; Arginine Vasopressin; Blood Pressure; Dioxanes; Dose-Response Relationship, Drug; Ganglionic Blockers; Gyrus Cinguli; Heart Rate; Hypophysectomy; Idazoxan; Male; Mecamylamine; Microinjections; Norepinephrine; Phenoxybenzamine; Rats; Rats, Wistar

2003
THE SITE OF THE 5-HYDROXYTRYPTAMINE RECEPTOR ON THE INTRAMURAL NERVOUS PLEXUS OF THE GUINEA-PIG ISOLATED ILEUM.
    British journal of pharmacology and chemotherapy, 1963, Volume: 21

    Topics: Acetylcholine; Animals; Autonomic Nervous System; Choline; Ganglia; Ganglia, Autonomic; Ganglionic Blockers; Guinea Pigs; Hexamethonium Compounds; Histamine; Ileum; Isoflurophate; Lysergic Acid Diethylamide; Mecamylamine; Muscle, Smooth; Nicotine; Organophosphate Poisoning; Pempidine; Pentolinium Tartrate; Pharmacology; Phenoxybenzamine; Phosphorus; Poisons; Procaine; Receptors, Serotonin; Research; Scopolamine; Serotonin

1963
[CONTRIBUTION TO THE STUDY OF EXPERIMENTAL MODELS OF ARTERIAL HYPERTENSION].
    Gaceta medica de Mexico, 1964, Volume: 94

    Topics: Animals; Chlorisondamine; Classification; Cortisone; Dogs; Ganglionic Blockers; Hydrochlorothiazide; Hyperaldosteronism; Hypertension; Hypertension, Renal; Kidney; Mecamylamine; Models, Theoretical; Pathology; Phenoxybenzamine; Physiology; Research

1964
SUSTAINED HYPERTENSION IN DOGS FOLLOWING CHRONIC ADMINISTRATION OF GANGLIONIC BLOCKING AGENTS.
    The Journal of pharmacology and experimental therapeutics, 1964, Volume: 144

    Topics: Animals; Blood Pressure; Chlorisondamine; Dogs; Ganglionic Blockers; Hydrochlorothiazide; Hypertension; Mecamylamine; Pharmacology; Phenoxybenzamine; Placebos; Research; Reserpine

1964
INNERVATION OF THE LARGE INTESTINE OF THE TOAD (BUFO MARINUS).
    British journal of pharmacology and chemotherapy, 1964, Volume: 23

    Topics: Acetylcholine; Anatomy, Comparative; Animals; Anura; Atropine; Autonomic Nervous System; Bretylium Compounds; Bufo marinus; Ganglionic Blockers; Hexamethonium Compounds; Intestine, Large; Isoproterenol; Mecamylamine; Norepinephrine; Pentolinium Tartrate; Pharmacology; Phenoxybenzamine; Physiology, Comparative; Physostigmine; Research; Reserpine; Splanchnic Nerves; Sympatholytics; Transferases

1964
Antinociceptive effect of stimulating the zona incerta with glutamate in rats.
    Pharmacology, biochemistry, and behavior, 2012, Volume: 101, Issue:3

    Topics: Analgesics; Animals; Atropine; Glutamic Acid; Haloperidol; Male; Mecamylamine; Methysergide; Microinjections; Naloxone; Pain; Pain Measurement; Phenoxybenzamine; Rats; Rats, Wistar; Subthalamic Nucleus; Subthalamus

2012