mecamylamine and naloxone

mecamylamine has been researched along with naloxone in 61 studies

Research

Studies (61)

Timeframe	Studies, this research(%)	All Research%
pre-1990	9 (14.75)	18.7374
1990's	20 (32.79)	18.2507
2000's	22 (36.07)	29.6817
2010's	9 (14.75)	24.3611
2020's	1 (1.64)	2.80

Authors

Authors	Studies
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Goldfarb, J; Jenkins, HR; Kaplan, EI	1
Huston-Lyons, D; Kornetsky, C	1
Antonelli, T; Beani, L; Bianchi, C; Ferraro, L; Morari, M; Nordberg, A; Spalluto, P; Tanganelli, S	1
Iwamoto, ET	1
Gebhart, GF; Zhuo, M	1
Cooley, JE; Fowler, SC; Lombardo, TW; Moss, RA; Sult, S; Villarosa, GA	1
Del Rio, J; Molinero, MT	1
Mayer, DJ; Watkins, LR	1
Malhotra, RK; Wakade, AR	1
Ludbrook, J; Potocnik, SJ; Rutter, PC	1
Bell, S; Jhamandas, K; Sutak, M	1
Dickinson, G; Jhamandas, K	1
Brase, DA; Loh, HH; Tseng, LF; Way, EL	1
Martin, WR; Wu, KM	1
Beleslin, DB; Jovanović-Mićić, D; Samardzić, R	1
Bley, KR; Bonhaus, DW; Broka, CA; Fontana, DJ; Leung, E; Lewis, R; Shieh, A; Wong, EH	1
Eyl, C; Hakan, RL; Hart, C	1
Erenmemisoglu, A; Tekol, Y	1
Marley, PD; Smardencas, A; Thomson, KA	1
Farzin, D; Zarrindast, MR	1
Mucha, RF	1
Benowitz, NL; Heller, PH; Levine, JD; Miao, FJ	1
Franco, AC; Prado, WA	1
Forsling, ML; Yasin, SA	1
Anderson, DJ; Barlocco, D; Bartolini, A; Cignarella, G; Colombo, D; Galeotti, N; Ghelardini, C; Kuntzweiler, TA; Toma, L; Tondi, D; Vianello, P; Villa, S	1
Adams, ML; Cicero, TJ	1
Pan, J; Shieh, K	1
Kalso, E; Kontinen, VK; Paananen, S; Pöyhiä, R; Xu, M	1
Dal Piaz, V; Galli, A; Giovannoni, MP; Matucci, R; Pieretti, S	1
Bortone, L; Carboni, E; Di Chiara, G; Giua, C	1
Koob, GF; Markou, A; Stinus, L; Watkins, SS	1
Ise, Y; Nagase, H; Narita, M; Suzuki, T	1
Oliveira, MA; Prado, WA	1
Barghi-Lashkari, S; Shafizadeh, M; Zarrindast, MR	1
Childs, E; Hahn, B; Morley, A; Stolerman, IP	1
Faraji, N; Ghoshouni, H; Rostami, P; Sahraei, H; Zarrindast, MR	1
Abe, K; Chikuma, T; Hojyo, H; Kato, M; Miyatake, T; Taguchi, K; Utsunomiya, I	1
Choi, JI; Jeong, SW; Yoon, MH	1
Bevins, RA; Palmatier, MI; Peterson, JL; Wilkinson, JL	1
Aso, E; Balerio, GN; Berrendero, F; Maldonado, R; Murtra, P	1
Galligan, JJ; Ren, J	1
Decker, MW; Honore, P; Lynch, JJ; Mikusa, JP; Wade, CL	1
DeNoble, VJ; Mele, PC	1
Biggio, G; Brundu, A; Concas, A; Marra, C; Porcu, P; Sogliano, C	1
Li, CL; Li, RT; Sun, Q; Ye, J; Yue, CQ	1
Alizadeh, AM; Haghparast, A; Khani, A; Motamedi, F; Naderi, N	1
Kiguchi, N; Kishioka, S; Maeda, T; Ozaki, M; Tsuruga, M; Yamamoto, A; Yamamoto, C	1
Honore, P; Joshi, SK; Mikusa, JP; Weaver, B	1
Cucchiaro, G; Gonzalez-Sulser, A; Kellar, KJ; Xiao, Y	1
Calixto, JB; Chaves, J; Ferreira, VM; Guginski, G; Luiz, AP; Martins, DF; Massaro, M; Mattos, RW; Santos, AR; Silva, MD; Silveira, D	1
Araki, H; Cui, R; Kohnomi, S; Li, B; Suemaru, K	1
Castelli, MP; Ennas, MG; Lecca, S; Luchicchi, A; Melis, M; Muntoni, AL; Pistis, M	1
Feng, YL; Lin, HM; Liu, YL; Qin, ZH; Reid, PF; Shi, GN; Yang, SL	1
Hoseindoost, S; Nasehi, M; Zarrindast, MR	1
Dias, QM; Fais, RS; Petronilho, A; Prado, WA; Reis, GM	1
Boylan, F; Fernandes, PD; Pinheiro, MM	1
Gruca, P; Lason-Tyburkiewicz, M; Litwa, E; Papp, M; Willner, P	1
Farshid, AA; Tamaddonfard, E; Yousofizadeh, S	1
Fernandes, PD; Giorno, TBS; Pinto, ADC; Silva, BVD	1
Browne, T; Carranza-Aguilar, CJ; Cruz, SL; Espinosa-Riquer, ZP; Ruiz-Quiñonez, AK	1

Reviews

2 review(s) available for mecamylamine and naloxone

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Multiple endogenous opiate and non-opiate analgesia systems: evidence of their existence and clinical implications. Annals of the New York Academy of Sciences, 1986, Volume: 467 Topics: Acupuncture Therapy; Analgesia; Animals; Cholecystokinin; Conditioning, Classical; Desipramine; Dimethyl Sulfoxide; Drug Interactions; Electroshock; Endorphins; Enkephalin, Leucine; Mecamylamine; Morphine; N-Methylscopolamine; Naloxone; Naltrexone; Norepinephrine; Proglumide; Rats; Receptors, Cell Surface; Receptors, Cholecystokinin; Scopolamine; Scopolamine Derivatives; Serotonin; Spinal Cord	1986

Article

Year

DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.

Drug discovery today, 2016, Volume: 21, Issue:4

Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Multiple endogenous opiate and non-opiate analgesia systems: evidence of their existence and clinical implications.

Annals of the New York Academy of Sciences, 1986, Volume: 467

Topics: Acupuncture Therapy; Analgesia; Animals; Cholecystokinin; Conditioning, Classical; Desipramine; Dimethyl Sulfoxide; Drug Interactions; Electroshock; Endorphins; Enkephalin, Leucine; Mecamylamine; Morphine; N-Methylscopolamine; Naloxone; Naltrexone; Norepinephrine; Proglumide; Rats; Receptors, Cell Surface; Receptors, Cholecystokinin; Scopolamine; Scopolamine Derivatives; Serotonin; Spinal Cord

1986

Other Studies

59 other study(ies) available for mecamylamine and naloxone

Article	Year
Interaction of morphine and naloxone in acute spinal cats. Neuropharmacology, 1978, Volume: 17, Issue:8 Topics: Animals; Atropine; Cats; Drug Interactions; Mecamylamine; Morphine; Naloxone; Reflex; Reflex, Monosynaptic; Spinal Cord; Time Factors	1978
Effects of nicotine on the threshold for rewarding brain stimulation in rats. Pharmacology, biochemistry, and behavior, 1992, Volume: 41, Issue:4 Topics: Animals; Brain; Electric Stimulation; Male; Mecamylamine; Naloxone; Nicotine; Rats; Rats, Inbred F344; Reward; Self Stimulation	1992
Effect of acute and subchronic nicotine treatment on cortical efflux of [3H]-D-aspartate and endogenous GABA in freely moving guinea-pigs. British journal of pharmacology, 1991, Volume: 104, Issue:1 Topics: Acetylcholine; Animals; Aspartic Acid; Cerebral Cortex; Female; gamma-Aminobutyric Acid; Guinea Pigs; Injections, Intraventricular; Injections, Subcutaneous; Male; Mecamylamine; Methysergide; Naloxone; Nicotine; Receptors, GABA-A; Receptors, Nicotinic	1991
Characterization of the antinociception induced by nicotine in the pedunculopontine tegmental nucleus and the nucleus raphe magnus. The Journal of pharmacology and experimental therapeutics, 1991, Volume: 257, Issue:1 Topics: Analgesia; Animals; Dioxolanes; Glutamates; Glutamic Acid; Hemicholinium 3; Male; Mecamylamine; Medulla Oblongata; Naloxone; Nicotine; Procainamide; Raphe Nuclei; Rats; Rats, Inbred Strains; Reflex	1991
Spinal serotonin receptors mediate descending facilitation of a nociceptive reflex from the nuclei reticularis gigantocellularis and gigantocellularis pars alpha in the rat. Brain research, 1991, May-31, Volume: 550, Issue:1 Topics: Amidines; Analysis of Variance; Animals; Atropine; Blood Pressure; Brain; Electric Stimulation; Heart Rate; Hot Temperature; Injections, Spinal; Male; Mecamylamine; Medulla Oblongata; Methysergide; Naloxone; Pain; Phentolamine; Rats; Rats, Inbred Strains; Receptors, Serotonin; Reflex; Serotonin Antagonists; Sodium Glutamate; Spinal Cord; Tropanes	1991
Effect of pCPA on nicotine-induced analgesia. Pharmacology, biochemistry, and behavior, 1990, Volume: 36, Issue:2 Topics: Analgesia; Animals; Drug Interactions; Fenclonine; Male; Mecamylamine; Naloxone; Nicotine; Pain; Rats; Rats, Inbred Strains; Sensory Thresholds	1990
Substance P, nicotinic acetylcholine receptors and antinociception in the rat. Neuropharmacology, 1987, Volume: 26, Issue:12 Topics: Analgesics; Animals; Hexamethonium Compounds; Injections, Intraventricular; Male; Mecamylamine; Naloxone; Neurokinin A; Neurokinin B; Neuropeptides; Nicotine; Rats; Rats, Inbred Strains; Reaction Time; Receptors, Cholinergic; Substance P	1987
Non-cholinergic component of rat splanchnic nerves predominates at low neuronal activity and is eliminated by naloxone. The Journal of physiology, 1987, Volume: 383 Topics: Acetylcholine; Adrenal Glands; Animals; Atropine; Catecholamines; Dose-Response Relationship, Drug; Electric Stimulation; Male; Mecamylamine; Naloxone; Rats; Receptors, Muscarinic; Receptors, Nicotinic; Splanchnic Nerves; Tetraethylammonium; Tetraethylammonium Compounds	1987
Factors influencing the effects of intravenous naloxone on arterial pressure and heart rate after haemorrhage in conscious rabbits. Clinical and experimental pharmacology & physiology, 1986, Volume: 13, Issue:5 Topics: Animals; Blood Pressure; Dose-Response Relationship, Drug; Epinephrine; Heart Rate; Hemorrhage; Mecamylamine; Naloxone; Norepinephrine; Rabbits	1986
Modification of precipitated morphine withdrawal syndrome by drugs affecting cholinergic mechanisms. European journal of pharmacology, 1973, Volume: 24, Issue:3 Topics: Animals; Atropine; Autonomic Nervous System; Diphenhydramine; Dose-Response Relationship, Drug; Drug Synergism; Humans; Imipramine; Mecamylamine; Morphine; Morphine Dependence; Naloxone; Neurotransmitter Agents; Physostigmine; Propranolol; Rats; Receptors, Adrenergic; Receptors, Cholinergic; Substance Withdrawal Syndrome; Synaptic Transmission; Tolazoline	1973
Modification of precipitated morphine and methadone abstinence in mice by acetylcholine antagonists. Nature: New biology, 1973, Oct-17, Volume: 245, Issue:146 Topics: Acetylcholine; Animals; Atropine; Drug Combinations; Humans; Mecamylamine; Methadone; Mice; Morphine; Morphine Dependence; Naloxone; Substance Withdrawal Syndrome; Substance-Related Disorders; Time Factors	1973
Cholinergic modification of naloxone-induced jumping in morphine dependent mice. European journal of pharmacology, 1974, Volume: 26, Issue:1 Topics: Animals; Arecoline; Atropine; Behavior, Animal; Benztropine; Brain Chemistry; Dimethylphenylpiperazinium Iodide; Humans; Lobeline; Male; Mecamylamine; Mice; Mice, Inbred ICR; Morphine Dependence; Naloxone; Nicotine; Oxotremorine; Parasympatholytics; Parasympathomimetics; Pempidine; Physostigmine; Pilocarpine; Tremorine; Tritium	1974
An analysis of nicotinic and opioid processes in the medulla oblongata and nucleus ambiguus of the dog. The Journal of pharmacology and experimental therapeutics, 1983, Volume: 227, Issue:2 Topics: Animals; Blood Pressure; Cyclazocine; Decerebrate State; Dogs; Electric Stimulation; Endorphins; Ethylketocyclazocine; Female; Fentanyl; Heart Rate; Male; Mecamylamine; Medulla Oblongata; Naloxone; Nicotine; Phenazocine; Receptors, Opioid; Receptors, Opioid, kappa; Receptors, Opioid, mu; Receptors, sigma	1983
The role of alpha-adrenergic mechanisms within the area postrema in dopamine-induced emesis. European journal of pharmacology, 1995, Jan-05, Volume: 272, Issue:1 Topics: Adrenergic alpha-Antagonists; alpha-Methyltyrosine; Animals; Atropine; Cats; Cerebral Ventricles; Dioxanes; Disease Models, Animal; Dopamine; Dopamine Antagonists; Dose-Response Relationship, Drug; Female; Hemicholinium 3; Idazoxan; Injections, Intraventricular; Male; Mecamylamine; Methyltyrosines; Methysergide; Naloxone; Oxidopamine; Prazosin; Reserpine; Tolazoline; Tyrosine 3-Monooxygenase; Vomiting; Yohimbine	1995
Characterization of the electrophysiological, biochemical and behavioral actions of epibatidine. The Journal of pharmacology and experimental therapeutics, 1995, Volume: 272, Issue:3 Topics: Analgesics; Animals; Binding, Competitive; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Guinea Pigs; In Vitro Techniques; Male; Mecamylamine; Morphine; Motor Activity; Naloxone; Nicotinic Agonists; Pyridines; Radioligand Assay; Rats; Receptors, Nicotinic; Stereoisomerism; Vagus Nerve	1995
Specific neurophysiological effects of systemic nicotine on neurons in the nucleus accumbens. Synapse (New York, N.Y.), 1993, Volume: 15, Issue:3 Topics: Action Potentials; Animals; Dopamine; Electric Stimulation; Haloperidol; Hexamethonium; Hexamethonium Compounds; Male; Mecamylamine; Morphine; Naloxone; Neurons; Nicotine; Nucleus Accumbens; Rats; Rats, Sprague-Dawley	1993
Do nicotine metabolites have an effect on pain perception? Antinociceptive effect of cotinine in mice. Die Pharmazie, 1994, Volume: 49, Issue:5 Topics: Analgesics; Animals; Cotinine; Dose-Response Relationship, Drug; Female; Male; Mecamylamine; Mice; Naloxone; Pain Measurement	1994
Non-cholinergic nervous control of catecholamine secretion from perfused bovine adrenal glands. The Journal of physiology, 1993, Volume: 465 Topics: Adrenal Glands; Animals; Atropine; Catecholamines; Cattle; Electric Stimulation; Epinephrine; In Vitro Techniques; Mecamylamine; Naloxone; Norepinephrine; Parasympathetic Nervous System; Tetrodotoxin	1993
Nicotine attenuates naloxone-induced jumping behaviour in morphine-dependent mice. European journal of pharmacology, 1996, Feb-29, Volume: 298, Issue:1 Topics: Animals; Atropine; Behavior, Animal; Benzazepines; Hexamethonium; Male; Mecamylamine; Mice; Morphine Dependence; Naloxone; Narcotic Antagonists; Nicotine; Phenoxybenzamine; Propranolol; Substance P; Substance Withdrawal Syndrome; Sulpiride	1996
Preferences for tastes paired with a nicotine antagonist in rats chronically treated with nicotine. Pharmacology, biochemistry, and behavior, 1997, Volume: 56, Issue:2 Topics: Animals; Conditioning, Psychological; Fentanyl; Food Preferences; Male; Mecamylamine; Naloxone; Narcotic Antagonists; Narcotics; Nicotine; Nicotinic Antagonists; Rats; Rats, Sprague-Dawley; Taste	1997
Contribution of adrenal hormones to nicotine-induced inhibition of synovial plasma extravasation in the rat. British journal of pharmacology, 1997, Volume: 120, Issue:2 Topics: Adrenal Glands; Animals; Bradykinin; Capillary Permeability; Male; Mecamylamine; Mifepristone; Naloxone; Nicotine; Platelet Activating Factor; Propanolamines; Rats; Rats, Sprague-Dawley	1997
Antinociceptive effects of stimulation of discrete sites in the rat hypothalamus: evidence for the participation of the lateral hypothalamus area in descending pain suppression mechanisms. Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 1996, Volume: 29, Issue:11 Topics: Adrenergic alpha-Antagonists; Analgesia; Analgesics, Opioid; Animals; Atropine; Dopamine Antagonists; Electric Stimulation; Haloperidol; Hypothalamic Area, Lateral; Male; Mecamylamine; Methysergide; Morphine; Muscarinic Antagonists; Naloxone; Narcotic Antagonists; Nicotinic Antagonists; Pain; Phenoxybenzamine; Rats; Rats, Wistar; Serotonin Antagonists	1996
Mechanisms of melatonin inhibition of neurohypophysial hormone release from the rat hypothalamus in vitro. Brain research bulletin, 1998, Volume: 45, Issue:1 Topics: Animals; Atenolol; Atropine; Haloperidol; Hypothalamus; Ibuprofen; In Vitro Techniques; Male; Mecamylamine; Melatonin; Naloxone; Oxytocin; Phentolamine; Rats; Rats, Wistar; Receptors, Neurotransmitter; Reproducibility of Results; Vasopressins	1998
Mono- and disubstituted-3,8-diazabicyclo[3.2.1]octane derivatives as analgesics structurally related to epibatidine: synthesis, activity, and modeling. Journal of medicinal chemistry, 1998, Feb-26, Volume: 41, Issue:5 Topics: Abdominal Muscles; Analgesia; Analgesics, Non-Narcotic; Animals; Bridged Bicyclo Compounds, Heterocyclic; Cerebral Cortex; Humans; Kinetics; Magnetic Resonance Spectroscopy; Male; Mecamylamine; Mice; Models, Molecular; Molecular Conformation; Muscle Contraction; Naloxone; Narcotic Antagonists; Pain Threshold; Pyridazines; Pyridines; Rats; Receptors, Cholinergic	1998
Nitric oxide mediates mecamylamine- and naloxone-precipitated nicotine withdrawal. European journal of pharmacology, 1998, Mar-19, Volume: 345, Issue:2 Topics: Animals; Male; Mecamylamine; Naloxone; NG-Nitroarginine Methyl Ester; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Nitric Oxide; Rats; Rats, Sprague-Dawley; Substance Withdrawal Syndrome	1998
Ontogeny of the diurnal rhythm of tuberoinfundibular dopaminergic neuronal activity in peripubertal female rats: possible involvement of cholinergic and opioidergic systems. Neuroendocrinology, 1998, Volume: 68, Issue:6 Topics: Animals; Circadian Rhythm; Dopamine; Female; Limbic System; Male; Mecamylamine; Naloxone; Narcotic Antagonists; Neostriatum; Neurons; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Opioid Peptides; Parasympathetic Nervous System; Prolactin; Rats; Rats, Sprague-Dawley; Sexual Maturation	1998
Systemic physostigmine shows antiallodynic effects in neuropathic rats. Anesthesia and analgesia, 1999, Volume: 89, Issue:2 Topics: Analgesics; Analgesics, Opioid; Animals; Atropine; Cholinergic Antagonists; Dose-Response Relationship, Drug; Injections, Subcutaneous; Ligation; Male; Mecamylamine; Morphine; Naloxone; Narcotic Antagonists; Pain; Pain Measurement; Pain Threshold; Peripheral Nervous System Diseases; Physostigmine; Rats; Rats, Sprague-Dawley; Spinal Nerves	1999
Antinociceptive activity of a 3(2H)-pyridazinone derivative in mice. Life sciences, 1999, Volume: 65, Issue:13 Topics: Analgesics, Non-Narcotic; Animals; Dose-Response Relationship, Drug; Male; Mecamylamine; Mice; Motor Activity; Muscarinic Agonists; Naloxone; Pyridazines	1999
Dissociation of physical abstinence signs from changes in extracellular dopamine in the nucleus accumbens and in the prefrontal cortex of nicotine dependent rats. Drug and alcohol dependence, 2000, Feb-01, Volume: 58, Issue:1-2 Topics: Analysis of Variance; Animals; Behavior, Animal; Dopamine; Infusion Pumps, Implantable; Male; Mecamylamine; Naloxone; Narcotic Antagonists; Nicotine; Nicotinic Antagonists; Nucleus Accumbens; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Substance Withdrawal Syndrome	2000
Reward and somatic changes during precipitated nicotine withdrawal in rats: centrally and peripherally mediated effects. The Journal of pharmacology and experimental therapeutics, 2000, Volume: 292, Issue:3 Topics: Animals; Brain; Chlorisondamine; Injections, Intraventricular; Male; Mecamylamine; Naloxone; Nicotine; Rats; Rats, Wistar; Receptors, Nicotinic; Reward; Substance Withdrawal Syndrome	2000
Modulation of opioidergic system on mecamylamine-precipitated nicotine-withdrawal aversion in rats. Psychopharmacology, 2000, Volume: 151, Issue:1 Topics: Analgesics; Animals; Male; Mecamylamine; Naloxone; Narcotic Antagonists; Nicotine; Nicotinic Antagonists; Quinolines; Rats; Rats, Sprague-Dawley; Receptors, Opioid; Substance Withdrawal Syndrome	2000
Role of PAG in the antinociception evoked from the medial or central amygdala in rats. Brain research bulletin, 2001, Jan-01, Volume: 54, Issue:1 Topics: Adrenergic beta-Antagonists; Amygdala; Anesthetics, Local; Animals; Atropine; Electric Stimulation; Ganglionic Blockers; Lidocaine; Male; Mecamylamine; Methysergide; Microinjections; Naloxone; Naltrexone; Narcotic Antagonists; Nociceptors; Pain Threshold; Parasympatholytics; Periaqueductal Gray; Propranolol; Rats; Rats, Wistar; Serotonin Antagonists	2001
The possible cross-tolerance between morphine- and nicotine-induced hypothermia in mice. Pharmacology, biochemistry, and behavior, 2001, Volume: 68, Issue:2 Topics: Animals; Body Temperature; Drug Interactions; Drug Tolerance; Hexamethonium; Hypothermia, Induced; Male; Mecamylamine; Mice; Morphine; Naloxone; Narcotic Antagonists; Narcotics; Nicotine; Nicotinic Agonists; Nicotinic Antagonists	2001
Drug trace discrimination with nicotine and morphine in rats. Behavioural pharmacology, 2002, Volume: 13, Issue:1 Topics: Animals; Discrimination Learning; Dose-Response Relationship, Drug; Extinction, Psychological; Male; Mecamylamine; Mental Recall; Morphine; Naloxone; Nicotine; Rats	2002
Cross-tolerance between morphine- and nicotine-induced conditioned place preference in mice. Pharmacology, biochemistry, and behavior, 2003, Volume: 74, Issue:2 Topics: Animals; Conditioning, Operant; Dose-Response Relationship, Drug; Drug Tolerance; Female; Mecamylamine; Mice; Morphine; Naloxone; Narcotic Antagonists; Narcotics; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Receptors, Opioid	2003
Characterization of muscarinic receptor subtypes in the rostral ventrolateral medulla and effects on morphine-induced antinociception in rats. European journal of pharmacology, 2003, Apr-04, Volume: 465, Issue:3 Topics: Analgesics, Opioid; Animals; Atropine; Diamines; Male; Mecamylamine; Medulla Oblongata; Microinjections; Morphine; Naloxone; Narcotic Antagonists; Pain Measurement; Piperidines; Pirenzepine; Rats; Rats, Wistar; Receptor, Muscarinic M1; Receptor, Muscarinic M2; Receptor, Muscarinic M3; Time Factors	2003
Spinal gabapentin and antinociception: mechanisms of action. Journal of Korean medical science, 2003, Volume: 18, Issue:2 Topics: Acetates; Adrenergic alpha-Antagonists; Adrenergic Antagonists; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amines; Analgesics; Animals; Atropine; Cyclohexanecarboxylic Acids; Dihydroergocristine; Enzyme Inhibitors; Excitatory Amino Acid Agonists; GABA Antagonists; Gabapentin; gamma-Aminobutyric Acid; Injections, Spinal; Leucine; Male; Mecamylamine; Muscarinic Antagonists; N-Methylaspartate; Naloxone; Narcotic Antagonists; Nicotinic Antagonists; Pain Measurement; Quinazolines; Rats; Rats, Sprague-Dawley; Serine; Spinal Cord; Thapsigargin; Triazoles	2003
Nicotine serves as a feature-positive modulator of Pavlovian appetitive conditioning in rats. Behavioural pharmacology, 2004, Volume: 15, Issue:3 Topics: Animals; Appetitive Behavior; Choice Behavior; Conditioning, Classical; Discrimination Learning; Discrimination, Psychological; Dose-Response Relationship, Drug; Drug Administration Schedule; Hexamethonium; Male; Mecamylamine; Naloxone; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Rats; Rats, Sprague-Dawley; Reward	2004
Delta9-tetrahydrocannabinol decreases somatic and motivational manifestations of nicotine withdrawal in mice. The European journal of neuroscience, 2004, Volume: 20, Issue:10 Topics: Analgesics, Non-Narcotic; Analysis of Variance; Animals; Autoradiography; Behavior, Animal; Benzoxazines; Brain; Calcium Channel Blockers; Cell Count; Conditioning, Operant; Dronabinol; Drug Administration Schedule; Drug Interactions; Immunohistochemistry; In Vitro Techniques; Male; Mecamylamine; Mice; Morpholines; Motivation; Naloxone; Naphthalenes; Narcotic Antagonists; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Proto-Oncogene Proteins c-fos; Radioligand Assay; Substance Withdrawal Syndrome	2004
Dynamics of fast synaptic excitation during trains of stimulation in myenteric neurons of guinea-pig ileum. Autonomic neuroscience : basic & clinical, 2005, Feb-07, Volume: 117, Issue:2 Topics: Acetylcholine; Action Potentials; Adenosine A1 Receptor Antagonists; Adenosine Triphosphate; Adrenergic alpha-2 Receptor Antagonists; Animals; Dose-Response Relationship, Radiation; Drug Interactions; Electric Stimulation; Estriol; Excitatory Postsynaptic Potentials; GABA Antagonists; Guinea Pigs; Idazoxan; Ileum; In Vitro Techniques; Iontophoresis; Male; Mecamylamine; Myenteric Plexus; Naloxone; Narcotic Antagonists; Neural Inhibition; Neurons; Nicotinic Antagonists; Peptides; Picrotoxin; Piperazines; Platelet Aggregation Inhibitors; Pyridoxal Phosphate; Serotonin 5-HT1 Receptor Antagonists; Theophylline; Time Factors	2005
ABT-594 (a nicotinic acetylcholine agonist): anti-allodynia in a rat chemotherapy-induced pain model. European journal of pharmacology, 2005, Feb-10, Volume: 509, Issue:1 Topics: Acetylcholine; Analgesia; Animals; Azetidines; Chlorisondamine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Routes; Drug Administration Schedule; Drug Evaluation, Preclinical; Drug Therapy, Combination; Humans; Mecamylamine; Naloxone; Nicotinic Agonists; Pain; Pyridines; Rats; Rats, Sprague-Dawley; Time Factors; Vincristine	2005
Intravenous nicotine self-administration in rats: effects of mecamylamine, hexamethonium and naloxone. Psychopharmacology, 2006, Volume: 184, Issue:3-4 Topics: Animals; Association Learning; Brain; Conditioning, Operant; Disease Models, Animal; Dose-Response Relationship, Drug; Hexamethonium; Humans; Infusions, Intravenous; Male; Mecamylamine; Naloxone; Nicotine; Nicotinic Antagonists; Rats; Rats, Long-Evans; Receptors, Nicotinic; Receptors, Opioid; Reinforcement Schedule	2006
Neurosteroids in nicotine and morphine dependence. Psychopharmacology, 2006, Volume: 186, Issue:3 Topics: Analgesics, Opioid; Animals; Cerebral Cortex; Male; Mecamylamine; Morphine; Naloxone; Narcotic Antagonists; Narcotics; Nicotine; Nicotinic Antagonists; Pregnanolone; Pregnenolone; Progesterone; Rats; Rats, Sprague-Dawley; Substance Withdrawal Syndrome	2006
Antinociceptive effects of the novel spirocyclopiperazinium salt compound LXM-10 in mice. Pharmacology, biochemistry, and behavior, 2007, Volume: 86, Issue:4 Topics: Analgesics; Animals; Atropine; Atropine Derivatives; Body Temperature; Drug Evaluation, Preclinical; Female; Hexamethonium; Male; Mecamylamine; Mice; Mice, Inbred ICR; Motor Activity; Naloxone; Pain; Pain Measurement; Piperazines; Psychomotor Performance; Receptors, Adrenergic, alpha-2; Receptors, Muscarinic; Receptors, Nicotinic; Receptors, Opioid; Yohimbine	2007
Repeated administration of nicotine attenuates the development of morphine tolerance and dependence in mice. Pharmacology, biochemistry, and behavior, 2008, Volume: 88, Issue:4 Topics: Analgesics, Opioid; Animals; Atropine; Dose-Response Relationship, Drug; Drug Tolerance; Ganglionic Blockers; Hexamethonium Compounds; Male; Mecamylamine; Mice; Morphine; Morphine Dependence; Muscarinic Antagonists; Naloxone; Narcotic Antagonists; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Pain Measurement; Substance Withdrawal Syndrome	2008
Involvement of spinal Met-enkephalin in nicotine-induced antinociception in mice. Brain research, 2008, Jan-16, Volume: 1189 Topics: Analgesics; Animals; Dose-Response Relationship, Drug; Down-Regulation; Dynorphins; Enkephalin, Methionine; Enkephalins; Male; Mecamylamine; Mice; Mice, Inbred ICR; Naloxone; Narcotic Antagonists; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Nociceptors; Pain; Pain Measurement; Pain Threshold; Posterior Horn Cells; Pro-Opiomelanocortin; Protein Precursors; RNA, Messenger	2008
Morphine and ABT-594 (a nicotinic acetylcholine agonist) exert centrally mediated antinociception in the rat cyclophosphamide cystitis model of visceral pain. The journal of pain, 2008, Volume: 9, Issue:2 Topics: Analgesics; Animals; Azetidines; Behavior, Animal; Brain; Chlorisondamine; Cyclophosphamide; Cystitis; Disease Models, Animal; Male; Mecamylamine; Morphine; Naloxone; Narcotic Antagonists; Nicotinic Antagonists; Pain; Pyridines; Quaternary Ammonium Compounds; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic; Viscera	2008
Analgesic effects of Sazetidine-A, a new nicotinic cholinergic drug. Anesthesiology, 2008, Volume: 109, Issue:3 Topics: Analgesics; Animals; Azetidines; Bridged Bicyclo Compounds, Heterocyclic; Cholinergic Agents; Disease Models, Animal; Dose-Response Relationship, Drug; Male; Mecamylamine; Motor Activity; Naloxone; Narcotic Antagonists; Nicotinic Agonists; Nicotinic Antagonists; Pain; Pain Measurement; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic; Sodium Chloride	2008
Mechanisms involved in the antinociception caused by ethanolic extract obtained from the leaves of Melissa officinalis (lemon balm) in mice. Pharmacology, biochemistry, and behavior, 2009, Volume: 93, Issue:1 Topics: Acetic Acid; Analgesics; Animals; Arginine; Atropine; Cinnamates; Depsides; Dose-Response Relationship, Drug; Female; Formaldehyde; Glutamic Acid; Male; Mecamylamine; Melissa; Mice; Motor Activity; Naloxone; Nitric Oxide; Pain; Pain Threshold; Phytotherapy; Plant Extracts; Plant Leaves; Receptors, Muscarinic; Receptors, Nicotinic; Rosmarinic Acid	2009
Tropisetron attenuates naloxone-induced place aversion in single-dose morphine-treated rats: role of alpha7 nicotinic receptors. European journal of pharmacology, 2009, May-01, Volume: 609, Issue:1-3 Topics: Aconitine; Animals; Conditioning, Psychological; Dose-Response Relationship, Drug; Indoles; Male; Mecamylamine; Morphine; Naloxone; Narcotic Antagonists; Narcotics; Nicotinic Agonists; Nicotinic Antagonists; Ondansetron; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic; Serotonin Antagonists; Tropisetron	2009
Effects of drugs of abuse on putative rostromedial tegmental neurons, inhibitory afferents to midbrain dopamine cells. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2011, Volume: 36, Issue:3 Topics: Action Potentials; Animals; Animals, Newborn; Behavior, Animal; Benzoxazines; Cocaine; Dopamine; Drug Interactions; Electric Stimulation; Excitatory Postsynaptic Potentials; Gene Expression Regulation; Illicit Drugs; In Vitro Techniques; Male; Mecamylamine; Morphine; Morpholines; Naloxone; Naphthalenes; Narcotic Antagonists; Neural Inhibition; Neural Pathways; Neurons; Nicotinic Antagonists; Patch-Clamp Techniques; Piperidines; Pyrazoles; Rats; Rats, Sprague-Dawley; Rimonabant; Time Factors; Ventral Tegmental Area	2011
Involvement of cholinergic system in suppression of formalin-induced inflammatory pain by cobratoxin. Acta pharmacologica Sinica, 2011, Volume: 32, Issue:10 Topics: Aconitine; Adjuvants, Anesthesia; Analgesics; Animals; Antihypertensive Agents; Atropine; Cobra Neurotoxin Proteins; Drug Interactions; Formaldehyde; Male; Mecamylamine; Naloxone; Narcotic Antagonists; Nicotinic Antagonists; Pain; Rats; Rats, Sprague-Dawley; Receptors, Cholinergic	2011
Possible interaction between opioidergic and cholinergic systems of CA1 in cholestasis-induced amnesia in mice. Behavioural brain research, 2012, Mar-01, Volume: 228, Issue:1 Topics: Amnesia; Animals; Animals, Outbred Strains; CA1 Region, Hippocampal; Cholestasis; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Therapy, Combination; Exploratory Behavior; Male; Mecamylamine; Mental Recall; Mice; Microinjections; Muscarinic Antagonists; Naloxone; Narcotic Antagonists; Nicotinic Antagonists; Receptors, Opioid; Scopolamine	2012
Antinociceptive effect of stimulating the zona incerta with glutamate in rats. Pharmacology, biochemistry, and behavior, 2012, Volume: 101, Issue:3 Topics: Analgesics; Animals; Atropine; Glutamic Acid; Haloperidol; Male; Mecamylamine; Methysergide; Microinjections; Naloxone; Pain; Pain Measurement; Phenoxybenzamine; Rats; Rats, Wistar; Subthalamic Nucleus; Subthalamus	2012
Antinociceptive effect of the Orbignya speciosa Mart. (Babassu) leaves: evidence for the involvement of apigenin. Life sciences, 2012, Sep-24, Volume: 91, Issue:9-10 Topics: Analgesics; Animals; Apigenin; Arecaceae; Aspirin; Atropine; Brazil; Disease Models, Animal; Dose-Response Relationship, Drug; Male; Mecamylamine; Mice; Morphine; Naloxone; Pain; Plant Extracts; Plant Leaves	2012
Effects of chronic mild stress on the development of drug dependence in rats. Behavioural pharmacology, 2014, Volume: 25, Issue:5-6 Topics: Animals; Chronic Disease; Citalopram; Depressive Disorder; Diazepam; Disease Models, Animal; Flumazenil; GABA Modulators; Male; Mecamylamine; Morphine; Naloxone; Narcotic Antagonists; Narcotics; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Rats, Wistar; Selective Serotonin Reuptake Inhibitors; Stress, Psychological; Substance Withdrawal Syndrome; Substance-Related Disorders	2014
The role of nicotinic acetylcholine and opioid systems of the ventral orbital cortex in modulation of formalin-induced orofacial pain in rats. European journal of pharmacology, 2015, Jul-05, Volume: 758 Topics: Analgesics, Opioid; Animals; Bridged Bicyclo Compounds, Heterocyclic; Drug Therapy, Combination; Facial Pain; Formaldehyde; Locomotion; Male; Mecamylamine; Microinjections; Morphine; Naloxone; Narcotic Antagonists; Nicotinic Agonists; Nicotinic Antagonists; Pain Measurement; Prefrontal Cortex; Pyridines; Rats	2015
Antinociceptive effect and mechanism of action of isatin, N-methyl isatin and oxopropyl isatin in mice. Life sciences, 2016, Apr-15, Volume: 151 Topics: Analgesics; Animals; Atropine; Dose-Response Relationship, Drug; Isatin; Mecamylamine; Mice; Morphine; Naloxone; NG-Nitroarginine Methyl Ester; Ondansetron; Pain; Pain Measurement	2016
Co-administration of morphine and levamisole increases death risk, produces neutropenia and modifies antinociception in mice. Addiction biology, 2022, Volume: 27, Issue:3 Topics: Analgesics; Animals; Levamisole; Male; Mecamylamine; Mice; Morphine; Naloxone; Neutropenia	2022