mecamylamine has been researched along with morphine in 74 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 27 (36.49) | 18.7374 |
| 1990's | 10 (13.51) | 18.2507 |
| 2000's | 21 (28.38) | 29.6817 |
| 2010's | 15 (20.27) | 24.3611 |
| 2020's | 1 (1.35) | 2.80 |
| Authors | Studies |
|---|---|
| Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Kato, R; Muraki, T; Nakadate, T; Tokunaga, Y | 1 |
| Ahtee, L; Kaakkola, S | 1 |
| Goldfarb, J; Jenkins, HR; Kaplan, EI | 1 |
| Furukawa, K | 1 |
| Chance, WT; Rosecrans, JA; Schechter, MD | 1 |
| Venho, VM | 1 |
| Flores, CM; Hornby, PJ; Hulihan-Giblin, BA; Kellar, KJ; Lumpkin, MD | 1 |
| Hulihan-Giblin, BA; Kellar, KJ; Lumpkin, MD | 1 |
| Flores, CM; Hulihan-Giblin, BA; Kellar, KJ | 1 |
| Mayer, DJ; Watkins, LR | 1 |
| Contreras, E; Rifo, J; Tamayo, L | 1 |
| Bell, S; Jhamandas, K; Sutak, M | 1 |
| György, L; Phan, DV | 1 |
| Eyzaguirre, C; Zapata, P | 1 |
| Goldenberg, MM | 1 |
| Flacke, W; Gillis, RA | 1 |
| Dhattiwala, AS; Jindal, MN; Kelkar, VV | 1 |
| Akubue, PI | 1 |
| Aceto, MD; Bentley, HC; Dembinski, JR | 1 |
| Dickinson, G; Jhamandas, K | 1 |
| Bass, P; Kennedy, JA; Wiley, JN | 1 |
| Kent, TH; Summers, RW | 1 |
| Hatch, RC | 1 |
| Holsti, LR; Mattila, MJ; Takki, S; Venho, VM | 1 |
| Kent, TH; Osborne, JW; Summers, RW | 1 |
| Nikki, P | 1 |
| Botting, JH; Turmer, AD | 1 |
| Bley, KR; Bonhaus, DW; Broka, CA; Fontana, DJ; Leung, E; Lewis, R; Shieh, A; Wong, EH | 1 |
| Eyl, C; Hakan, RL; Hart, C | 1 |
| Naguib, M; Yaksh, TL | 1 |
| Lichtman, AH; Martin, BR; Smith, FL | 1 |
| Franco, AC; Prado, WA | 1 |
| Arneric, SP; Bannon, AW; Bitner, RS; Curzon, P; Decker, MW; Diaz, A; Dickenson, AH; Donnelly-Roberts, D; Holladay, MW; Porsolt, RD; Puttfarcken, PS; Williams, M | 1 |
| Arneric, SP; Bannon, AW; Buckley, MJ; Decker, MW; Holladay, MW; Kim, DJ; Lin, NH; Ryther, KB; Wasicak, JT; Williams, M | 1 |
| Kalso, E; Kontinen, VK; Paananen, S; Pöyhiä, R; Xu, M | 1 |
| Barghi-Lashkari, S; Shafizadeh, M; Zarrindast, MR | 1 |
| Chen, SR; Pan, HL | 1 |
| Gear, RW; Levine, JD; Schmidt, BL; Tambeli, CH | 1 |
| Childs, E; Hahn, B; Morley, A; Stolerman, IP | 1 |
| Faraji, N; Ghoshouni, H; Rostami, P; Sahraei, H; Zarrindast, MR | 1 |
| Abe, K; Chikuma, T; Hojyo, H; Kato, M; Miyatake, T; Taguchi, K; Utsunomiya, I | 1 |
| GOKHALE, SD; GULATI, OD; JOSHI, NY | 1 |
| LEVI, R; MAYNERT, EW | 1 |
| Brussaard, AB; De Rover, M; Lodder, JC; Schoffelmeer, AN | 1 |
| Fattahi, Z; Rezayof, A; Rostami, P; Zarrindast, MR | 1 |
| Biggio, G; Brundu, A; Concas, A; Marra, C; Porcu, P; Sogliano, C | 1 |
| Haeri-Rohani, A; Rezayof, A; Zarrindast, MR; Zatali, H | 1 |
| Glick, SD; Livi, JM; Maisonneuve, IM; Ramirez, RL | 1 |
| Delphi, L; Nazari-Serenjeh, F; Rezayof, A; Sepehri, H; Zarrindast, MR | 1 |
| Baskett, JA; Kracke, GR; Lever, JR; Miller, DK; Rodvelt, KR; Will, MJ | 1 |
| Collins, AC; Damaj, MI; Deshpande, P; Fonck, C; Labarca, C; Lester, HA; Marks, MJ; Martin, BR | 1 |
| Alizadeh, AM; Haghparast, A; Khani, A; Motamedi, F; Naderi, N | 1 |
| Honore, P; Joshi, SK; Mikusa, JP; Weaver, B | 1 |
| Khajehpour, L; Rezayof, A; Zarrindast, MR | 1 |
| Darbandi, N; Rezayof, A; Zarrindast, MR | 1 |
| Steidl, S; Yeomans, JS | 1 |
| Araki, H; Cui, R; Kohnomi, S; Li, B; Suemaru, K | 1 |
| Arihan, O; Boz, M; Ilhan, M; Iskit, AB | 1 |
| Biala, G; Budzynska, B; Staniak, N | 1 |
| Biala, G; Staniak, N | 1 |
| Dyhr, H; Grunnet, M; Munro, G | 1 |
| Castelli, MP; Ennas, MG; Lecca, S; Luchicchi, A; Melis, M; Muntoni, AL; Pistis, M | 1 |
| Boylan, F; Fernandes, PD; Pinheiro, MM | 1 |
| Alijanpour, S; Assadpour, S; Rezayof, A | 1 |
| Cunningham, CS; McMahon, LR | 1 |
| Gawel, K; Jenda, M; Kotlinska, JH; Labuz, K; Silberring, J | 1 |
| Gruca, P; Lason-Tyburkiewicz, M; Litwa, E; Papp, M; Willner, P | 1 |
| Rezayof, A; Tirgar, F; Zarrindast, MR | 1 |
| Farshid, AA; Tamaddonfard, E; Yousofizadeh, S | 1 |
| Fernandes, PD; Giorno, TBS; Pinto, ADC; Silva, BVD | 1 |
| Cui, R; Li, X; Ruan, H; Sun, J; Tian, L | 1 |
| Browne, T; Carranza-Aguilar, CJ; Cruz, SL; Espinosa-Riquer, ZP; Ruiz-Quiñonez, AK | 1 |
2 review(s) available for mecamylamine and morphine
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Multiple endogenous opiate and non-opiate analgesia systems: evidence of their existence and clinical implications.
Topics: Acupuncture Therapy; Analgesia; Animals; Cholecystokinin; Conditioning, Classical; Desipramine; Dimethyl Sulfoxide; Drug Interactions; Electroshock; Endorphins; Enkephalin, Leucine; Mecamylamine; Morphine; N-Methylscopolamine; Naloxone; Naltrexone; Norepinephrine; Proglumide; Rats; Receptors, Cell Surface; Receptors, Cholecystokinin; Scopolamine; Scopolamine Derivatives; Serotonin; Spinal Cord | 1986 |
72 other study(ies) available for mecamylamine and morphine
| Article | Year |
|---|---|
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding | 2012 |
Inhibition by cholinergic agonists of the prolactin release induced by morphine.
Topics: Animals; Atropine; Haloperidol; Male; Mecamylamine; Methyltyrosines; Morphine; Parasympathomimetics; Physostigmine; Pilocarpine; Prolactin; Rats | 1979 |
Effect of mecamylamine on the fate of dopamine in striatal and mesolimbic areas of rat brain; interaction with morphine and haloperidol.
Topics: Animals; Catalepsy; Corpus Striatum; Dopamine; Drug Interactions; Haloperidol; Homovanillic Acid; Humans; Limbic System; Male; Mecamylamine; Methyltyrosines; Morphine; Rats | 1978 |
Interaction of morphine and naloxone in acute spinal cats.
Topics: Animals; Atropine; Cats; Drug Interactions; Mecamylamine; Morphine; Naloxone; Reflex; Reflex, Monosynaptic; Spinal Cord; Time Factors | 1978 |
[Mechanisms of contraction and relaxation in the response to 5'hydroxytriptamine of isolated rat ileum (author's transl)].
Topics: Animals; Dose-Response Relationship, Drug; Drug Synergism; Hydroxydopamines; Ileum; In Vitro Techniques; Male; Mecamylamine; Methysergide; Morphine; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Physostigmine; Rats; Receptors, Drug; Serotonin; Serotonin Antagonists; Tetrodotoxin | 1978 |
The discriminative stimulus properties of nicotine, d-amphetamine and morphine in dopamine depleted rats.
Topics: Animals; Brain Chemistry; Dextroamphetamine; Dopamine; Female; Hydroxydopamines; Mecamylamine; Morphine; Nicotine; Pregnancy; Rats; Time Factors | 1976 |
Absorption of morphine, butylscopolamine, mecamylamine and phenobarbitone from the small intestine of the triparanol-treated rat in situ.
Topics: Animals; Depression, Chemical; Female; Intestinal Absorption; Intestine, Small; Mecamylamine; Morphine; Perfusion; Phenobarbital; Rats; Scopolamine Derivatives; Stimulation, Chemical; Time Factors; Triparanol | 1975 |
Partial characterization of a neurotransmitter pathway regulating the in vivo release of prolactin.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Bromocriptine; Haloperidol; Male; Mecamylamine; Methysergide; Morphine; Naltrexone; Narcotic Antagonists; Neurotransmitter Agents; Nicotine; Nicotinic Antagonists; Pituitary Gland; Prolactin; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Nicotinic; Receptors, Opioid; Receptors, Serotonin; Serotonin Antagonists; Tetrahydronaphthalenes | 1992 |
Acute effects of nicotine on prolactin release in the rat: agonist and antagonist effects of a single injection of nicotine.
Topics: Animals; Brain; Dose-Response Relationship, Drug; Injections, Intraventricular; Male; Mecamylamine; Morphine; Nicotine; Prolactin; Rats; Rats, Inbred Strains; Receptors, Nicotinic | 1990 |
Naltrexone blocks nicotine-induced prolactin release.
Topics: Animals; Catheterization; Male; Mecamylamine; Morphine; Naltrexone; Nicotine; Prolactin; Rats; Rats, Inbred Strains | 1989 |
Influence of adrenergic and cholinergic mechanisms in baclofen induced analgesia.
Topics: Analgesics; Animals; Atropine; Baclofen; Dose-Response Relationship, Drug; In Vitro Techniques; Mecamylamine; Mice; Morphine; Motor Activity; Neostigmine; Parasympathetic Nervous System; Physostigmine; Reaction Time; Sympathetic Nervous System | 1988 |
Modification of precipitated morphine withdrawal syndrome by drugs affecting cholinergic mechanisms.
Topics: Animals; Atropine; Autonomic Nervous System; Diphenhydramine; Dose-Response Relationship, Drug; Drug Synergism; Humans; Imipramine; Mecamylamine; Morphine; Morphine Dependence; Naloxone; Neurotransmitter Agents; Physostigmine; Propranolol; Rats; Receptors, Adrenergic; Receptors, Cholinergic; Substance Withdrawal Syndrome; Synaptic Transmission; Tolazoline | 1973 |
The pressor effect of oxotremorine and arecoline in rats.
Topics: Adrenalectomy; Adrenergic alpha-Antagonists; Animals; Arecoline; Atropine; Blood Pressure; Cerebral Ventricles; Cordotomy; Female; Ganglionic Blockers; Hexamethonium Compounds; Male; Mecamylamine; Morphine; Oxotremorine; Phenoxybenzamine; Phentolamine; Rats; Reserpine; Vagotomy | 1973 |
Pharmacology of pH effects on carotid body chemoreceptors in vitro.
Topics: Acetylcholine; Acetylcholinesterase; Action Potentials; Animals; Atropine; Calcium; Carotid Body; Cats; Chemoreceptor Cells; Choline; Hexamethonium Compounds; Hydrogen-Ion Concentration; Hypoxia; Magnesium; Mecamylamine; Membrane Potentials; Methods; Morphine; Parasympatholytics; Perfusion; Physostigmine; Potassium; Pressoreceptors; Succinylcholine; Synaptic Transmission | 1968 |
Angiotensin in the analysis of the intrinsic nerve supply of isolated intestines.
Topics: Angiotensin II; Animals; Atropine; Cocaine; Epinephrine; Gerbillinae; Hexamethonium Compounds; Ileum; Intestines; Mecamylamine; Mice; Morphine; Motor Neurons; Muscle Contraction; Muscle, Smooth; Papaverine; Pentolinium Tartrate; Procaine; Rats | 1968 |
Impulse transmission via nicotinic and muscarinic pathways in the stellate ganglion of the dog.
Topics: Animals; Atropine; Biphenyl Compounds; Blood Pressure; Chlorisondamine; Dogs; Electric Stimulation; Extracorporeal Circulation; Heart Rate; Hexamethonium Compounds; Mecamylamine; Morphine; Nicotine; Parasympathetic Nervous System; Parasympatholytics; Physostigmine; Stellate Ganglion; Sympathetic Nervous System; Synaptic Transmission; Tetraethylammonium Compounds; Tubocurarine; Vagus Nerve | 1968 |
Effects of some drugs on the responses of the rat isolated, innervated urinary bladder to indirect electrical stimulation.
Topics: Animals; Carbamates; Chloral Hydrate; Choline; Electric Stimulation; Evoked Potentials; Female; Hexamethonium Compounds; Humans; In Vitro Techniques; Mecamylamine; Morphine; Morpholines; Muscle, Smooth; Neuromuscular Junction; Paraldehyde; Phrenic Nerve; Pyridazines; Quaternary Ammonium Compounds; Rats; Strychnine; Synaptic Transmission; Tubocurarine; Urinary Bladder | 1970 |
The site of action of drugs on the isolated taenia caeci from the guinea-pig.
Topics: Acetylcholine; Animals; Cecum; Cocaine; Female; Guinea Pigs; Hexamethonium Compounds; Histamine; Histamine H1 Antagonists; In Vitro Techniques; Insecticides; Lysergic Acid Diethylamide; Male; Mecamylamine; Morphine; Muscle Contraction; Nicotine; Piperazines; Procaine; Scopolamine; Serotonin; Sympathomimetics | 1966 |
Effects of ganglion blocking agents on nicotine extensor convulsions and lethality in mice.
Topics: Animals; Atropine; Cerebral Ventricles; Chlorisondamine; Chlorpromazine; Decamethonium Compounds; Ganglionic Blockers; Hexamethonium Compounds; Male; Mecamylamine; Mice; Morphine; Nicotine; Phenobarbital; Seizures | 1969 |
Modification of precipitated morphine and methadone abstinence in mice by acetylcholine antagonists.
Topics: Acetylcholine; Animals; Atropine; Drug Combinations; Humans; Mecamylamine; Methadone; Mice; Morphine; Morphine Dependence; Naloxone; Substance Withdrawal Syndrome; Substance-Related Disorders; Time Factors | 1973 |
Measurement of fecal output in rats.
Topics: 5-Hydroxytryptophan; Amphetamine; Animals; Apomorphine; Atropine; Chlorpromazine; Codeine; Cyclazocine; Digestive System; Feces; Housing, Animal; Levallorphan; Magnesium Sulfate; Male; Mecamylamine; Meperidine; Methotrimeprazine; Methylamines; Mineral Oil; Morphine; Muscle, Smooth; Opium; Papaverine; Pentazocine; Rats | 1972 |
Effects of altered propulsion on rat small intestinal flora.
Topics: Animals; Bacteria; Bacteroides; Chlorisondamine; Clostridium; Enterobacteriaceae; Escherichia coli; Fasting; Gastrointestinal Motility; Intestinal Obstruction; Intestine, Small; Lactobacillus; Male; Mecamylamine; Micrococcus; Morphine; Neostigmine; Peptic Ulcer; Radiation Effects; Rats; Staphylococcus; Streptococcus; Tolazoline | 1970 |
Effect of drugs on catnip (Nepeta cataria)-induced pleasure behavior in cats.
Topics: Amphetamine; Animals; Atropine; Behavior, Animal; Cats; Chlorpheniramine; Chlorpromazine; Drug Synergism; Female; Hexamethonium Compounds; Histidine; Lactones; Magnoliopsida; Male; Mecamylamine; Methysergide; Morphine; Neostigmine; Phenytoin; Physostigmine; Pilocarpine; Plant Extracts; Propranolol; Pyrans; Salivation; Serotonin; Sexual Behavior, Animal | 1972 |
Absorption of drugs in vitro from the rat intestine damaged by triparanol or irradiation.
Topics: Aminopyrine; Analgesics; Animals; Aspirin; Depression, Chemical; Ethionamide; Female; Intestinal Absorption; Intestine, Small; Mecamylamine; Morphine; Phenobarbital; Radiation Effects; Radiation Injuries, Experimental; Rats; Scopolamine; Stimulation, Chemical; Triparanol | 1970 |
Effects of drugs, ileal obstruction, and irradiation on rat gastrointestinal propulsion.
Topics: Animals; Chlorisondamine; Chlorpromazine; Chromium Isotopes; Fasting; Gastrointestinal Motility; Ileum; Indomethacin; Intestinal Obstruction; Male; Mecamylamine; Morphine; Neostigmine; Peptic Ulcer; Radiation Effects; Rats; Stomach; Tolazoline | 1970 |
Influence of some cholinomimetic and cholinolytic drugs on halothane shivering in mice.
Topics: Anesthesia, Inhalation; Animals; Atropine; Body Temperature Regulation; Drug Synergism; Halothane; Hexamethonium Compounds; Mecamylamine; Methane; Methoxyflurane; Mice; Morphine; Nicotine; Nicotinic Acids; Parasympatholytics; Parasympathomimetics; Physostigmine; Temperature; Time Factors | 1968 |
Mode of action of vasopressin on isolated proximal colon of the guinea-pig.
Topics: Acetylcholine; Animals; Calcium; Carbachol; Cocaine; Cold Temperature; Colon; Guinea Pigs; Hexamethonium Compounds; Histamine; Hypoxia; In Vitro Techniques; Mecamylamine; Morphine; Muscle Contraction; Nicotine; Pentolinium Tartrate; Procaine; Scopolamine; Serotonin; Tetraethylammonium Compounds; Vasopressins | 1966 |
Characterization of the electrophysiological, biochemical and behavioral actions of epibatidine.
Topics: Analgesics; Animals; Binding, Competitive; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Guinea Pigs; In Vitro Techniques; Male; Mecamylamine; Morphine; Motor Activity; Naloxone; Nicotinic Agonists; Pyridines; Radioligand Assay; Rats; Receptors, Nicotinic; Stereoisomerism; Vagus Nerve | 1995 |
Specific neurophysiological effects of systemic nicotine on neurons in the nucleus accumbens.
Topics: Action Potentials; Animals; Dopamine; Electric Stimulation; Haloperidol; Hexamethonium; Hexamethonium Compounds; Male; Mecamylamine; Morphine; Naloxone; Neurons; Nicotine; Nucleus Accumbens; Rats; Rats, Sprague-Dawley | 1993 |
Antinociceptive effects of spinal cholinesterase inhibition and isobolographic analysis of the interaction with mu and alpha 2 receptor systems.
Topics: Animals; Atropine; Behavior, Animal; Carbachol; Clonidine; Dose-Response Relationship, Drug; Edrophonium; Hot Temperature; Injections, Spinal; Male; Mecamylamine; Morphine; Neostigmine; Neuromuscular Blocking Agents; Pain Threshold; Premedication; Rats; Rats, Sprague-Dawley; Reaction Time | 1994 |
Evidence that the antinociceptive tail-flick response is produced independently from changes in either tail-skin temperature or core temperature.
Topics: Analgesics; Animals; Body Temperature; Dronabinol; Hot Temperature; Immersion; Male; Mecamylamine; Mice; Mice, Inbred ICR; Morphine; Pain Measurement; Skin Temperature; Tail | 1993 |
Antinociceptive effects of stimulation of discrete sites in the rat hypothalamus: evidence for the participation of the lateral hypothalamus area in descending pain suppression mechanisms.
Topics: Adrenergic alpha-Antagonists; Analgesia; Analgesics, Opioid; Animals; Atropine; Dopamine Antagonists; Electric Stimulation; Haloperidol; Hypothalamic Area, Lateral; Male; Mecamylamine; Methysergide; Morphine; Muscarinic Antagonists; Naloxone; Narcotic Antagonists; Nicotinic Antagonists; Pain; Phenoxybenzamine; Rats; Rats, Wistar; Serotonin Antagonists | 1996 |
Broad-spectrum, non-opioid analgesic activity by selective modulation of neuronal nicotinic acetylcholine receptors.
Topics: Analgesics, Non-Narcotic; Animals; Azetidines; Bridged Bicyclo Compounds, Heterocyclic; Capsaicin; Dose-Response Relationship, Drug; In Vitro Techniques; Ligands; Mecamylamine; Morphine; Nerve Fibers; Neuromuscular Junction; Neurons; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Pain; Pain Measurement; Pyridines; Rats; Receptors, Nicotinic; Spinal Cord; Substance Withdrawal Syndrome; Synaptic Transmission | 1998 |
Antinociceptive effects of the novel neuronal nicotinic acetylcholine receptor agonist, ABT-594, in mice.
Topics: Analgesics, Non-Narcotic; Animals; Azetidines; Hexamethonium; Lethal Dose 50; Male; Maze Learning; Mecamylamine; Mice; Morphine; Motor Activity; Naltrexone; Narcotic Antagonists; Neurons; Nicotinic Agonists; Nicotinic Antagonists; Pain; Pyridines | 1998 |
Systemic physostigmine shows antiallodynic effects in neuropathic rats.
Topics: Analgesics; Analgesics, Opioid; Animals; Atropine; Cholinergic Antagonists; Dose-Response Relationship, Drug; Injections, Subcutaneous; Ligation; Male; Mecamylamine; Morphine; Naloxone; Narcotic Antagonists; Pain; Pain Measurement; Pain Threshold; Peripheral Nervous System Diseases; Physostigmine; Rats; Rats, Sprague-Dawley; Spinal Nerves | 1999 |
The possible cross-tolerance between morphine- and nicotine-induced hypothermia in mice.
Topics: Animals; Body Temperature; Drug Interactions; Drug Tolerance; Hexamethonium; Hypothermia, Induced; Male; Mecamylamine; Mice; Morphine; Naloxone; Narcotic Antagonists; Narcotics; Nicotine; Nicotinic Agonists; Nicotinic Antagonists | 2001 |
Spinal endogenous acetylcholine contributes to the analgesic effect of systemic morphine in rats.
Topics: Acetylcholine; Analgesics, Opioid; Animals; Atropine; Aziridines; Carrier Proteins; Choline; Cholinergic Agents; Hemicholinium 3; Injections, Spinal; Male; Mecamylamine; Membrane Transport Proteins; Morphine; Muscarinic Antagonists; Nicotinic Antagonists; Pain Measurement; Protein Binding; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; Receptors, Nicotinic; Spinal Cord | 2001 |
Nicotine withdrawal hyperalgesia and opioid-mediated analgesia depend on nicotine receptors in nucleus accumbens.
Topics: Analgesia; Animals; Capsaicin; Dose-Response Relationship, Drug; Drug Interactions; Drug Tolerance; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Hyperalgesia; Male; Mecamylamine; Morphine; Narcotics; Nicotine; Nicotinic Antagonists; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic; Substance Withdrawal Syndrome; Tobacco Use Disorder | 2001 |
Drug trace discrimination with nicotine and morphine in rats.
Topics: Animals; Discrimination Learning; Dose-Response Relationship, Drug; Extinction, Psychological; Male; Mecamylamine; Mental Recall; Morphine; Naloxone; Nicotine; Rats | 2002 |
Cross-tolerance between morphine- and nicotine-induced conditioned place preference in mice.
Topics: Animals; Conditioning, Operant; Dose-Response Relationship, Drug; Drug Tolerance; Female; Mecamylamine; Mice; Morphine; Naloxone; Narcotic Antagonists; Narcotics; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Receptors, Opioid | 2003 |
Characterization of muscarinic receptor subtypes in the rostral ventrolateral medulla and effects on morphine-induced antinociception in rats.
Topics: Analgesics, Opioid; Animals; Atropine; Diamines; Male; Mecamylamine; Medulla Oblongata; Microinjections; Morphine; Naloxone; Narcotic Antagonists; Pain Measurement; Piperidines; Pirenzepine; Rats; Rats, Wistar; Receptor, Muscarinic M1; Receptor, Muscarinic M2; Receptor, Muscarinic M3; Time Factors | 2003 |
EFFECT OF SOME BLOCKING DRUGS ON THE PRESSOR RESPONSE TO PHYSOSTIGMINE IN THE RAT.
Topics: Atropine; Blood Pressure; Bretylium Compounds; Chlorpromazine; Choline; Epinephrine; Guanethidine; Hexamethonium; Hexamethonium Compounds; Mecamylamine; Morphine; Norepinephrine; Pharmacology; Physostigmine; Rats; Research; Vasoconstrictor Agents | 1963 |
STRESS-INDUCED RELEASE OF BRAIN NOREPINEPHRINE AND ITS INHIBITION BY DRUGS.
Topics: Acetylcholine; Adrenal Glands; Atropine; Brain; Brain Stem; Cats; Chlorpromazine; Cold Temperature; Electric Stimulation; Electrophysiology; Enzyme Inhibitors; Epinephrine; Mecamylamine; Metabolism; Morphine; Norepinephrine; Pharmacology; Phenobarbital; Physiology; Rats; Research; Serotonin; Stress, Physiological | 1964 |
Intermittent morphine treatment induces a long-lasting increase in cholinergic modulation of GABAergic synapses in nucleus accumbens of adult rats.
Topics: Acetylcholine; Amphetamine; Anesthetics, Local; Animals; Central Nervous System Stimulants; Drug Interactions; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Mecamylamine; Membrane Potentials; Morphine; Narcotics; Neural Inhibition; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Nucleus Accumbens; Rats; Rats, Wistar; Synapses; Tetrodotoxin | 2005 |
Role of the cholinergic system in the rat basolateral amygdala on morphine-induced conditioned place preference.
Topics: Amygdala; Animals; Atropine; Conditioning, Psychological; Dose-Response Relationship, Drug; Male; Mecamylamine; Morphine; Nicotinic Antagonists; Rats; Rats, Wistar; Receptors, Cholinergic | 2005 |
Neurosteroids in nicotine and morphine dependence.
Topics: Analgesics, Opioid; Animals; Cerebral Cortex; Male; Mecamylamine; Morphine; Naloxone; Narcotic Antagonists; Narcotics; Nicotine; Nicotinic Antagonists; Pregnanolone; Pregnenolone; Progesterone; Rats; Rats, Sprague-Dawley; Substance Withdrawal Syndrome | 2006 |
Dorsal hippocampal muscarinic and nicotinic receptors are involved in mediating morphine reward.
Topics: Analysis of Variance; Animals; Atropine; Behavior, Animal; Cholinesterase Inhibitors; Conditioning, Operant; Dose-Response Relationship, Drug; Drug Interactions; Hippocampus; Male; Mecamylamine; Morphine; Motor Activity; Muscarinic Antagonists; Narcotics; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Physostigmine; Rats; Rats, Wistar; Receptors, Muscarinic; Receptors, Nicotinic; Reward | 2006 |
18-Methoxycoronaridine acts in the medial habenula and/or interpeduncular nucleus to decrease morphine self-administration in rats.
Topics: Animals; Behavior, Addictive; Conotoxins; Female; Habenula; Ibogaine; Mecamylamine; Mesencephalon; Morphine; Morphine Dependence; Narcotics; Nicotinic Antagonists; Rats; Rats, Long-Evans; Receptors, Nicotinic; Self Administration; Sucrose | 2006 |
Morphine-induced place preference: involvement of cholinergic receptors of the ventral tegmental area.
Topics: Analgesics, Opioid; Analysis of Variance; Animals; Atropine; Behavior, Animal; Cholinesterase Inhibitors; Conditioning, Operant; Dose-Response Relationship, Drug; Injections, Subcutaneous; Male; Mecamylamine; Morphine; Motor Activity; Muscarinic Antagonists; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Physostigmine; Rats; Rats, Wistar; Receptors, Cholinergic; Ventral Tegmental Area | 2007 |
Lobeline, a potential pharmacotherapy for drug addiction, binds to mu opioid receptors and diminishes the effects of opioid receptor agonists.
Topics: Analgesics, Opioid; Animals; Binding, Competitive; Brain; Dopamine; Dose-Response Relationship, Drug; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Guinea Pigs; In Vitro Techniques; Lobeline; Mecamylamine; Morphine; Naltrexone; Narcotic Antagonists; Narcotics; Nicotine; Oocytes; Radioligand Assay; Receptors, Opioid; Receptors, Opioid, mu; Xenopus laevis | 2007 |
Genetic approaches identify differential roles for alpha4beta2* nicotinic receptors in acute models of antinociception in mice.
Topics: Alkaloids; Analgesics; Animals; Azocines; Binding, Competitive; Bridged Bicyclo Compounds, Heterocyclic; Bungarotoxins; Cell Membrane; Male; Mecamylamine; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Inbred CBA; Mice, Inbred DBA; Mice, Inbred Strains; Mice, Knockout; Morphine; Nicotine; Nicotinic Antagonists; Pain; Pyridines; Quinolizines; Reaction Time; Receptors, Nicotinic; Spinal Cord | 2007 |
Repeated administration of nicotine attenuates the development of morphine tolerance and dependence in mice.
Topics: Analgesics, Opioid; Animals; Atropine; Dose-Response Relationship, Drug; Drug Tolerance; Ganglionic Blockers; Hexamethonium Compounds; Male; Mecamylamine; Mice; Morphine; Morphine Dependence; Muscarinic Antagonists; Naloxone; Narcotic Antagonists; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Pain Measurement; Substance Withdrawal Syndrome | 2008 |
Morphine and ABT-594 (a nicotinic acetylcholine agonist) exert centrally mediated antinociception in the rat cyclophosphamide cystitis model of visceral pain.
Topics: Analgesics; Animals; Azetidines; Behavior, Animal; Brain; Chlorisondamine; Cyclophosphamide; Cystitis; Disease Models, Animal; Male; Mecamylamine; Morphine; Naloxone; Narcotic Antagonists; Nicotinic Antagonists; Pain; Pyridines; Quaternary Ammonium Compounds; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic; Viscera | 2008 |
Involvement of dorsal hippocampal nicotinic receptors in the effect of morphine on memory retrieval in passive avoidance task.
Topics: Amnesia; Analgesics, Opioid; Animals; Behavior, Animal; Conditioning, Psychological; Dose-Response Relationship, Drug; Hippocampus; Injections, Subcutaneous; Male; Mecamylamine; Mental Recall; Microinjections; Morphine; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Rats; Rats, Wistar; Reaction Time; Receptors, Nicotinic | 2008 |
Nicotinic acetylcholine receptors of the ventral tegmental area are involved in mediating morphine-state-dependent learning.
Topics: Amnesia; Analgesics, Opioid; Animals; Avoidance Learning; Dose-Response Relationship, Drug; Drug Interactions; Male; Mecamylamine; Morphine; Neural Inhibition; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Rats; Rats, Wistar; Receptors, Nicotinic; Ventral Tegmental Area | 2008 |
M5 muscarinic receptor knockout mice show reduced morphine-induced locomotion but increased locomotion after cholinergic antagonism in the ventral tegmental area.
Topics: Animals; Atropine; Cholinergic Antagonists; Crosses, Genetic; Homozygote; Locomotion; Mecamylamine; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Mice, Knockout; Morphine; Motor Activity; Naltrexone; Receptor, Muscarinic M5; Ventral Tegmental Area | 2009 |
Tropisetron attenuates naloxone-induced place aversion in single-dose morphine-treated rats: role of alpha7 nicotinic receptors.
Topics: Aconitine; Animals; Conditioning, Psychological; Dose-Response Relationship, Drug; Indoles; Male; Mecamylamine; Morphine; Naloxone; Narcotic Antagonists; Narcotics; Nicotinic Agonists; Nicotinic Antagonists; Ondansetron; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic; Serotonin Antagonists; Tropisetron | 2009 |
Antinociceptive activity of coniine in mice.
Topics: Acetic Acid; Alkaloids; Analgesics; Animals; Conium; Drug Synergism; Male; Mecamylamine; Mice; Morphine; Nicotinic Antagonists; Pain; Piperidines; Plant Extracts | 2009 |
Effects of varenicline and mecamylamine on the acquisition, expression, and reinstatement of nicotine-conditioned place preference by drug priming in rats.
Topics: Animals; Benzazepines; Conditioning, Classical; Dose-Response Relationship, Drug; Male; Mecamylamine; Morphine; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Quinoxalines; Rats; Rats, Wistar; Receptors, Nicotinic; Reward; Tobacco Use Disorder; Varenicline | 2010 |
Varenicline and mecamylamine attenuate locomotor sensitization and cross-sensitization induced by nicotine and morphine in mice.
Topics: Analgesics, Opioid; Animals; Benzazepines; Dose-Response Relationship, Drug; Drug Interactions; Male; Mecamylamine; Mice; Morphine; Motor Activity; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Quinoxalines; Varenicline | 2010 |
Selective potentiation of gabapentin-mediated antinociception in the rat formalin test by the nicotinic acetylcholine receptor agonist ABT-594.
Topics: Amines; Analgesics; Animals; Azetidines; Cyclohexanecarboxylic Acids; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Duloxetine Hydrochloride; Exploratory Behavior; Gabapentin; gamma-Aminobutyric Acid; Male; Mecamylamine; Morphine; Nicotinic Agonists; Nicotinic Antagonists; Pain; Pain Measurement; Pyridines; Rats; Rats, Sprague-Dawley; Thiophenes | 2010 |
Effects of drugs of abuse on putative rostromedial tegmental neurons, inhibitory afferents to midbrain dopamine cells.
Topics: Action Potentials; Animals; Animals, Newborn; Behavior, Animal; Benzoxazines; Cocaine; Dopamine; Drug Interactions; Electric Stimulation; Excitatory Postsynaptic Potentials; Gene Expression Regulation; Illicit Drugs; In Vitro Techniques; Male; Mecamylamine; Morphine; Morpholines; Naloxone; Naphthalenes; Narcotic Antagonists; Neural Inhibition; Neural Pathways; Neurons; Nicotinic Antagonists; Patch-Clamp Techniques; Piperidines; Pyrazoles; Rats; Rats, Sprague-Dawley; Rimonabant; Time Factors; Ventral Tegmental Area | 2011 |
Antinociceptive effect of the Orbignya speciosa Mart. (Babassu) leaves: evidence for the involvement of apigenin.
Topics: Analgesics; Animals; Apigenin; Arecaceae; Aspirin; Atropine; Brazil; Disease Models, Animal; Dose-Response Relationship, Drug; Male; Mecamylamine; Mice; Morphine; Naloxone; Pain; Plant Extracts; Plant Leaves | 2012 |
Morphine-induced anxiolytic-like effect in morphine-sensitized mice: involvement of ventral hippocampal nicotinic acetylcholine receptors.
Topics: Animals; Animals, Outbred Strains; Anti-Anxiety Agents; Central Nervous System Sensitization; Hippocampus; Male; Maze Learning; Mecamylamine; Mice; Microinjections; Morphine; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Receptors, Nicotinic | 2013 |
Multiple nicotine training doses in mice as a basis for differentiating the effects of smoking cessation aids.
Topics: Alkaloids; Animals; Azocines; Benzazepines; Dihydro-beta-Erythroidine; Discrimination Learning; Dose-Response Relationship, Drug; Male; Mecamylamine; Mice; Mice, Inbred C57BL; Midazolam; Morphine; Nicotine; Nicotinic Agonists; Quinolizines; Quinoxalines; Receptors, Nicotinic; Smoking Cessation; Tobacco Use Cessation Devices; Varenicline | 2013 |
Influence of cholinesterase inhibitors, donepezil and rivastigmine on the acquisition, expression, and reinstatement of morphine-induced conditioned place preference in rats.
Topics: Animals; Cholinesterase Inhibitors; Conditioning, Psychological; Donepezil; Drug-Seeking Behavior; Indans; Male; Mecamylamine; Morphine; Motor Activity; Muscarinic Antagonists; Narcotics; Nicotinic Antagonists; Phenylcarbamates; Piperidines; Rats, Wistar; Rivastigmine; Scopolamine; Space Perception | 2014 |
Effects of chronic mild stress on the development of drug dependence in rats.
Topics: Animals; Chronic Disease; Citalopram; Depressive Disorder; Diazepam; Disease Models, Animal; Flumazenil; GABA Modulators; Male; Mecamylamine; Morphine; Naloxone; Narcotic Antagonists; Narcotics; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Rats, Wistar; Selective Serotonin Reuptake Inhibitors; Stress, Psychological; Substance Withdrawal Syndrome; Substance-Related Disorders | 2014 |
Central amygdala nicotinic and 5-HT1A receptors mediate the reversal effect of nicotine and MDMA on morphine-induced amnesia.
Topics: Amnesia; Animals; Central Amygdaloid Nucleus; Dose-Response Relationship, Drug; Male; Mecamylamine; Morphine; N-Methyl-3,4-methylenedioxyamphetamine; Narcotics; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Piperazines; Rats, Wistar; Receptor, Serotonin, 5-HT1A; Receptors, Nicotinic; Serotonin 5-HT1 Receptor Antagonists; Serotonin Agents | 2014 |
The role of nicotinic acetylcholine and opioid systems of the ventral orbital cortex in modulation of formalin-induced orofacial pain in rats.
Topics: Analgesics, Opioid; Animals; Bridged Bicyclo Compounds, Heterocyclic; Drug Therapy, Combination; Facial Pain; Formaldehyde; Locomotion; Male; Mecamylamine; Microinjections; Morphine; Naloxone; Narcotic Antagonists; Nicotinic Agonists; Nicotinic Antagonists; Pain Measurement; Prefrontal Cortex; Pyridines; Rats | 2015 |
Antinociceptive effect and mechanism of action of isatin, N-methyl isatin and oxopropyl isatin in mice.
Topics: Analgesics; Animals; Atropine; Dose-Response Relationship, Drug; Isatin; Mecamylamine; Mice; Morphine; Naloxone; NG-Nitroarginine Methyl Ester; Ondansetron; Pain; Pain Measurement | 2016 |
Muscarinic acetylcholine receptor but not nicotinic acetylcholine receptor plays a role in morphine-induced behavioral sensitization in rats.
Topics: Alkaloids; Animals; Behavior, Animal; Dose-Response Relationship, Drug; Locomotion; Male; Mecamylamine; Morphine; Rats; Rats, Wistar; Receptors, Muscarinic; Receptors, Nicotinic; Scopolamine; Sesquiterpenes | 2017 |
Co-administration of morphine and levamisole increases death risk, produces neutropenia and modifies antinociception in mice.
Topics: Analgesics; Animals; Levamisole; Male; Mecamylamine; Mice; Morphine; Naloxone; Neutropenia | 2022 |