mecamylamine and methyldopa

mecamylamine has been researched along with methyldopa in 23 studies

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-199021 (91.30)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (8.70)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Oparil, S; Rick, JH1
Fang, P; Kincaid-Smith, P; Laver, MC1
Brod, J1
Dhasmana, KM; Fokker, WA; Spilker, BA1
Carstens, E1
Dileo, RJ; Hidalgo, J; Tarleton, WA1
Finch, L1
Ito, S1
Beaven, MA; Gordon, JW; Jacobsen, S; Severs, WB1
Davis, RA1
Beckhelm, GA; Willard, PW1
Pomerantz, HZ1
Dalla Volta, S1
Ludden, CT; Stavorski, J; Stone, CA; Torchiana, ML; Wenger, HC1
Baum, T; Moran, RM; Sabin, C1
BADOUAL, J1
CHIRONE, E1
MILLIGAN, J; TURNER, RW1
BECKWITH, JR; CAMP, JL; MOSCA, A1
HARRIS, JE1
MEIRING, PD1

Reviews

3 review(s) available for mecamylamine and methyldopa

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
[Pathogenesis of essential hypertension with special reference to therapy].
    Wiener medizinische Wochenschrift (1946), 1971, Dec-04, Volume: 121, Issue:49

    Topics: Adolescent; Adrenal Glands; Adult; Aged; Angiotensin II; Blood Pressure; Blood Volume; Diazepam; Diuretics; Female; Guanethidine; Hexamethonium Compounds; Humans; Hypertension; Hypertension, Renal; Male; Mecamylamine; Methyldopa; Middle Aged; Phytotherapy; Plants, Medicinal; Psychophysiologic Disorders; Rauwolfia; Sleep; Time Factors; Vascular Resistance

1971
[MALIGNANT HYPERTENSION].
    Il Policlinico. Sezione pratica, 1964, Mar-02, Volume: 71

    Topics: Adrenalectomy; Angiotensins; Bretylium Compounds; Chlorisondamine; Diagnosis; Diet, Sodium-Restricted; Ganglionic Blockers; Guanethidine; Hexamethonium Compounds; Humans; Hydralazine; Hyperaldosteronism; Hypertension; Hypertension, Malignant; Mecamylamine; Methyldopa; Pathology; Pempidine; Pentolinium Tartrate; Prognosis; Renin; Sympathectomy

1964

Trials

1 trial(s) available for mecamylamine and methyldopa

ArticleYear
A new look at the treatment of severe hypertension.
    Clinical science and molecular medicine. Supplement, 1973, Volume: 45 Suppl 1

    Topics: Adrenergic beta-Antagonists; Adult; Antihypertensive Agents; Blood Pressure; Chlorothiazide; Clinical Trials as Topic; Diazoxide; Drug Synergism; Female; Humans; Hypertension; Male; Mecamylamine; Methyldopa; Middle Aged; Placebos; Spironolactone; Thiazines; Uremia

1973

Other Studies

19 other study(ies) available for mecamylamine and methyldopa

ArticleYear
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
Drug treatment of hypertension.
    Comprehensive therapy, 1977, Volume: 3, Issue:5

    Topics: Clonidine; Diazoxide; Diuretics; Ganglionic Blockers; Guanethidine; Humans; Hydralazine; Hypertension; Mecamylamine; Methyldopa; Mineralocorticoid Receptor Antagonists; Minoxidil; Nitroprusside; Prazosin; Propranolol; Secologanin Tryptamine Alkaloids; Sodium Chloride Symporter Inhibitors; Spironolactone; Sympatholytics; Triamterene; Trimethaphan; Vasodilator Agents

1977
Peripheral cardiovascular effects, in the pithed rat, of compounds used in the treatment of hypertension.
    British journal of pharmacology, 1972, Volume: 46, Issue:3

    Topics: Animals; Antihypertensive Agents; Blood Pressure; Clonidine; Cordotomy; Diazoxide; Electric Stimulation; Ergotamine; Guanethidine; Hydrochlorothiazide; Iproniazid; Male; Mecamylamine; Methyldopa; Pargyline; Phenobarbital; Rats; Reserpine; Sympathetic Nervous System; Thiocyanates; Trimethaphan

1972
[Antihypertensive agents].
    Die Pharmazie, 1972, Volume: 27, Issue:11

    Topics: Acetazolamide; Antihypertensive Agents; Bis-Trimethylammonium Compounds; Bretylium Compounds; Chlorisondamine; Chlorthalidone; Diuretics; Furosemide; Guanethidine; Guanidines; Hexamethonium Compounds; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Hypotension; Mecamylamine; Methyldopa; Pain; Parotid Gland; Pempidine; Phentolamine; Structure-Activity Relationship; Sulfonamides

1972
Teflon tubing in chronic arterial catheterization of monkeys.
    Proceedings of the Western Pharmacology Society, 1968, Volume: 11

    Topics: Animals; Blood Pressure; Catheterization; Fluorocarbon Polymers; Guanethidine; Haplorhini; Heart Rate; Hydralazine; Iliac Artery; Mecamylamine; Methods; Methyldopa; Placebos; Time Factors

1968
The neurogenic component in the experimental hypertensive rat.
    Pharmacology, 1971, Volume: 5, Issue:4

    Topics: Animals; Blood Pressure; Depression, Chemical; Desoxycorticosterone; Dihydroxyphenylalanine; Dopamine; Furosemide; Guanidines; Hypertension, Renal; Male; Mecamylamine; Methyldopa; Methyltyrosines; Pentobarbital; Rats; Reserpine; Sodium Chloride; Sympathetic Nervous System

1971
[Antihypertensive agents].
    Nihon rinsho. Japanese journal of clinical medicine, 1970, Mar-25, Volume: 28 Suppl

    Topics: Antihypertensive Agents; Humans; Hydralazine; Mecamylamine; Methyldopa; Pentolinium Tartrate; Phytotherapy; Plants, Medicinal; Rauwolfia

1970
Some observations on aminoguanidine pharmacology.
    Pharmacology, 1970, Volume: 3, Issue:4

    Topics: Amino Acids; Animals; Brain; Carbachol; Carboxy-Lyases; Cats; Denervation; Dihydroxyphenylalanine; Guanidines; Guinea Pigs; Histamine; Histidine; Mecamylamine; Methyldopa; Rats; Salivation; Stomach; Submandibular Gland; Transferases

1970
Induction of fatal hypothermia in house-mice.
    The Annals of applied biology, 1968, Volume: 61, Issue:2

    Topics: Animals; Body Temperature; Chlorpromazine; Hydralazine; Hypothermia; Mecamylamine; Methyldopa; Mice; Nialamide; Phenoxybenzamine; Pyrimidines; Sulfonamides

1968
Differential effect of hypotensive drugs on renal and steroid hypertensive rats.
    Archives internationales de pharmacodynamie et de therapie, 1968, Volume: 173, Issue:1

    Topics: Animals; Antihypertensive Agents; Benzothiadiazines; Bretylium Compounds; Desoxycorticosterone; Guanethidine; Hypertension; Hypertension, Renal; Mecamylamine; Methyldopa; Rats; Spironolactone

1968
Fourteen-year survival in a case of malignant hypertension under hypotensive drug therapy.
    Canadian Medical Association journal, 1968, Nov-30, Volume: 99, Issue:21

    Topics: Adult; Antihypertensive Agents; Chlorothiazide; Guanethidine; Hexamethonium Compounds; Humans; Hydralazine; Hydrochlorothiazide; Hypertension, Malignant; Male; Mecamylamine; Methyldopa; Pempidine; Pentolinium Tartrate; Phytotherapy; Plants, Medicinal; Rauwolfia

1968
[Medical therapy of arterial hypertension].
    Cardiologia pratica, 1968, Volume: 19, Issue:5

    Topics: Antihypertensive Agents; Arteries; Diuretics; Guanethidine; Humans; Hydrazines; Hypertension; Mecamylamine; Methyldopa; Phytotherapy; Plants, Medicinal; Rauwolfia; Reserpine

1968
Effect of methyldopa and related agents on pressor responses to tyramine in reserpine-pretreated rats and dogs.
    The Journal of pharmacology and experimental therapeutics, 1966, Volume: 151, Issue:2

    Topics: Animals; Blood Pressure; Dihydroxyphenylalanine; Dogs; Dopamine; Hormones; Mecamylamine; Metaraminol; Methyldopa; Monoamine Oxidase Inhibitors; Norepinephrine; Normetanephrine; Rats; Reserpine; Serine; Sympathomimetics; Tyramine

1966
Comparison of hypotensive, orthostatic and sympathetic inhibitory actions of antihypertensive drugs in rats.
    Clinical and experimental hypertension, 1981, Volume: 3, Issue:2

    Topics: Animals; Antihypertensive Agents; Blood Pressure; Clonidine; Diazepam; Guanethidine; Heart Rate; Hydralazine; Hypotension; Male; Mecamylamine; Methyldopa; Minoxidil; Phentolamine; Posture; Prazosin; Propranolol; Rats; Reserpine; Sympathetic Nervous System

1981
[New hypotensive medications: guanethidine, alphamethyldopa, mecamylamine].
    Vie medicale (Paris, France : 1920), 1963, Volume: 44

    Topics: Antihypertensive Agents; Guanethidine; Humans; Hypotension; Mecamylamine; Methyldopa

1963
HYPERTENSION AND ITS COMPLICATIONS. 2.
    Nursing times, 1964, Jun-26, Volume: 60

    Topics: Amobarbital; Antihypertensive Agents; Blood Pressure; Blood Pressure Determination; Cold Temperature; Diuretics; Guanethidine; Humans; Hypertension; Kidney Function Tests; Mecamylamine; Methyldopa; Nursing; Obesity; Ophthalmoscopy; Pempidine; Phenobarbital; Physical Exertion; Reserpine; Therapeutics; Toxicology

1964
RECENT TRENDS IN THE MEDICAL TREATMENT OF HYPERTENSION.
    Virginia medical monthly, 1964, Volume: 91

    Topics: Antihypertensive Agents; Diuretics; Guanethidine; Hydralazine; Hypertension; Mecamylamine; Methyldopa; Rauwolfia; Toxicology

1964
CARDIOVASCULAR RENAL AGENTS AS THEY IMPINGE ON OPHTHALMIC PRACTICE.
    Investigative ophthalmology, 1964, Volume: 3

    Topics: Antihypertensive Agents; Benzothiadiazines; Bretylium Compounds; Carbonic Anhydrase Inhibitors; Cardiovascular Agents; Diuretics; Drug Therapy; Glycerol; Guanethidine; Hexamethonium Compounds; Hydralazine; Mannitol; Mecamylamine; Methyldopa; Mineralocorticoid Receptor Antagonists; Ophthalmology; Organomercury Compounds; Pargyline; Pentolinium Tartrate; Renal Agents; Reserpine; Tetraethylammonium Compounds; Toxicology; Urea; Veratrum; Veratrum Alkaloids

1964
EXPERIENCES WITH THE LONG-TERM USE OF METHYLDOPA ("ALDOMET") IN HYPERTENSION.
    The Medical journal of Australia, 1965, Mar-20, Volume: 1, Issue:12

    Topics: Benzothiadiazines; Blood Pressure Determination; Depression; Drug Therapy; Drug Tolerance; Glomerulonephritis; Guanethidine; Hydralazine; Hypertension; Hypertension, Renal; Kidney Function Tests; Mecamylamine; Methyldopa; Pempidine; Pharmacology; Pyelonephritis; Reserpine; Toxicology

1965