mecamylamine has been researched along with hexamethonium in 85 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 20 (23.53) | 18.7374 |
| 1990's | 30 (35.29) | 18.2507 |
| 2000's | 22 (25.88) | 29.6817 |
| 2010's | 13 (15.29) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lambert, JJ; Nooney, JM; Peters, JA | 1 |
| Blank, E; Dodds, WJ; Greenwood, B | 1 |
| Abate, KL; Andresen, MJ; Hentall, ID; Wojcik, RS | 1 |
| Baker, M; Endoh, K; Kao, J; Leung, FW | 1 |
| Colquhoun, D; Edwards, FA; Gibb, AJ | 1 |
| Allen, Y; Arendt, T; Gray, JA; Hodges, H; Lantos, PL; Mitchell, SN; Sinden, J | 1 |
| Joseph, MH; Mitchell, SN; Smith, KM | 1 |
| Brazell, MP; Gray, JA; Mitchell, SN | 1 |
| Johnson, KM; Snell, LD | 1 |
| Blozovski, D; Hess, C | 1 |
| Bostwick, M; Martin, WR; Sloan, JW | 1 |
| Araki, Y; Furuno, K; Gomita, Y; Suemaru, K | 1 |
| Markus, JK; Mylecharane, EJ; Phillips, CA; Shaw, J | 1 |
| Gold, WM; Hartiala, JJ; Mapp, C; Mitchell, RA | 1 |
| Hassoni, AA; Kerkut, GA; Walker, RJ | 1 |
| Hayashi, E; Kagawa, Y; Kosuge, T; Takayanagi, N; Tsuji, K; Yamada, S | 1 |
| Freeman, GB; Gibson, GE; Sherman, KA | 1 |
| Edge, M; Kemp, G | 1 |
| Buccafusco, JJ; Elrod, K; Jackson, WJ | 1 |
| Baratti, CM; de Erausquin, GA; Faiman, CP | 1 |
| Bouhassira, D; Deschênes, M; Hu, B; Steriade, M | 1 |
| Clarke, PB; Kumar, R | 1 |
| Gibson, GE; Pelmas, CJ; Peterson, C | 1 |
| Garcha, HS; Giardini, V; Kumar, R; Pratt, JA; Stolerman, IP | 1 |
| Blazsó, G; Kac, P; Koltai, M; Minker, E | 1 |
| Klemm, WR | 1 |
| Dolezal, V; Hertting, G; Schobert, A | 1 |
| Jednak, MA; Judge, K; Ram, JL | 1 |
| Fernández, AG; Gristwood, RW; O'Neill, MF; Palacios, JM | 1 |
| Balfour, DJ; Benwell, ME; Birrell, CE | 1 |
| Changeux, JP; Vidal, C | 1 |
| Eyl, C; Hakan, RL; Hart, C | 1 |
| Chiou, GC; Li, BH | 1 |
| Riekkinen, M; Riekkinen, P; Tolonen, R | 1 |
| Gomita, Y; Oishi, R; Suemaru, K | 1 |
| Farzin, D; Zarrindast, MR | 1 |
| Savci, V; Ulus, IH | 1 |
| Oveisi, MR; Zarrindast, MR | 1 |
| MacDonald, E; Miettinen, R; Puumala, T; Riekkinen, P; Ruotsalainen, S; Sirviö, J | 1 |
| Akaike, A; Kihara, T; Kimura, J; Kochiyama, H; Kume, T; Maeda, T; Sawada, H; Shimohama, S | 1 |
| Blomqvist, O; Engel, JA; Ericson, M; Söderpalm, B | 1 |
| Chambers, EL; Ivonnet, PI | 1 |
| Borycz, J; Bugajski, J; Gadek-Michalska, A; Głód, R | 1 |
| Arneric, SP; Bannon, AW; Buckley, MJ; Decker, MW; Holladay, MW; Kim, DJ; Lin, NH; Ryther, KB; Wasicak, JT; Williams, M | 1 |
| Felipo, V; Grisolía, S; Llansola, M; Miñana, MD; Montoliu, C | 1 |
| Lindstrom, J; Nelson, ME | 1 |
| Rezayat, M; Shekarchi, M; Zarrindast, MR | 1 |
| Kordasti, S; Lundgren, O; Peregrin, AT; Persson, K; Svensson, L; Uhnoo, I | 1 |
| Engel, JA; Ericson, M; Olausson, P; Söderpalm, B | 1 |
| Dhar, S; McIntosh, JM; Nagy, F; Sapru, HN | 1 |
| Haeri-Zadeh, F; Lahiji, P; Zarghi, A; Zarrindast, MR | 1 |
| Mohaddess, G; Rezvani-Pour, M; Zarrindast, MR | 1 |
| Babaie, A; Etminani, A; Gharib, B; Homayoun, H; Zarrindast, MR | 1 |
| Besheer, J; Bevins, RA | 1 |
| Barghi-Lashkari, S; Shafizadeh, M; Zarrindast, MR | 1 |
| Aït-Oubah, J; Armengaud, C; Causse, N; Gauthier, M | 1 |
| Murakami, Y; Nakamura, K; Okada, S; Yokotani, K | 1 |
| Matsumoto, M; Ohashi, S; Saito, H; Togashi, H; Ueno, K; Yoshioka, M | 1 |
| Li, LJ; Liu, CG; Liu, W; Liu, ZW; Wan, Q; Zheng, JQ | 1 |
| Aikawa, Y; Hotta, H; Nakajima, K; Suzuki, A; Uchida, S | 1 |
| Kita, T; Kubo, K; Nakashima, T; Nakatani, T; Narushima, I; Tanaka, T | 1 |
| GOKHALE, SD; GULATI, OD; JOSHI, NY | 1 |
| BURN, JH; GIBBONS, WR | 1 |
| Marszalec, W; Moriguchi, S; Narahashi, T; Yeh, JZ; Zhao, X | 1 |
| de Châtel, R; Göõz, M; Göõz, P; Smolka, AJ; Szalay, KS; Tóth, M; Vakkuri, O | 1 |
| Bevins, RA; Palmatier, MI; Peterson, JL; Wilkinson, JL | 1 |
| Davis, TP; Egleton, RD; Hawkins, BT | 1 |
| Bevins, RA; Palmatier, MI; Siebert, HL; Wilkinson, JL; Wiltgen, SM | 1 |
| DeNoble, VJ; Mele, PC | 1 |
| Cunningham, CS; Jany, JR; Miller, DK; Polston, JE; Segert, IL | 1 |
| Li, CL; Li, RT; Sun, Q; Ye, J; Yue, CQ | 1 |
| Cansev, M; Hamurtekin, E; Ilcol, YO; Ulus, IH; Yilmaz, MS | 1 |
| Papke, RL; Stitzel, JA; Wecker, L | 1 |
| Dallery, J; Jones, J; Raiff, BR | 1 |
| Alvarez-Crespo, M; Dickson, SL; Egecioglu, E; Engel, JA; Hansson, C; Hrabovszky, E; Jerlhag, E; Liposits, Z; Molnar, CS; Skibicka, KP | 1 |
| Rahman, S; Roni, MA | 1 |
| Grady, SR; Marks, MJ; O'Neill, HC; Ortiz, NC | 1 |
| Nakamori, C; Shiina, T; Shimizu, Y | 1 |
| Magoski, NS; White, SH | 1 |
| Chazono, K; Iwajima, Y; Maeda, Y; Nagano, Y; Ohsawa, M; Ono, H; Yamamoto, S | 1 |
| Nylander, O; Saudi, WS; Sjöblom, M; Sommansson, A | 1 |
| Carter, CJ; Magoski, NS; White, SH | 1 |
| Albers, KM; Davis, BM; Diges, CM; Gold, MS; Schwartz, ES; Yang, CI; Zhang, XL | 1 |
| Lefebvre, RA; Pauwelyn, V | 1 |
| Cai, Y; Dai, Z; Liang, L; Mao, Y; Pan, L; Qi, R; Su, Y; Wang, J | 1 |
85 other study(ies) available for mecamylamine and hexamethonium
| Article | Year |
|---|---|
A patch clamp study of the nicotinic acetylcholine receptor of bovine adrenomedullary chromaffin cells in culture.
Topics: Acetylcholine; Adrenal Medulla; Animals; Cattle; Cell Membrane Permeability; Cesium; Evoked Potentials; Ganglionic Blockers; Hexamethonium; Hexamethonium Compounds; Ion Channels; Mecamylamine; Nicotinic Antagonists; Receptors, Nicotinic; Sodium; Trimethaphan; Tubocurarine | 1992 |
Nicotine stimulates esophageal peristaltic contractions in cats by a central mechanism.
Topics: Animals; Cats; Deglutition; Electromyography; Esophagus; Female; Hexamethonium; Hexamethonium Compounds; Injections, Intravenous; Male; Mecamylamine; Muscle Relaxation; Muscle, Smooth; Nicotine; Peristalsis; Reference Values; Succinylcholine; Vagotomy | 1992 |
Nicotinic activity in the interpeduncular nucleus of the midbrain prolongs recovery from halothane anesthesia.
Topics: Anesthesia Recovery Period; Animals; Brain; Female; Ganglionic Blockers; Halothane; Hexamethonium; Hexamethonium Compounds; Mecamylamine; Nicotine; Rats; Rats, Sprague-Dawley; Reflex, Abnormal | 1992 |
Intragastric nicotine protection against 40% ethanol injury in rat stomach. Role of ganglionic stimulation or blockade.
Topics: Animals; Blood Pressure; Ethanol; Ganglia, Sympathetic; Ganglionic Blockers; Ganglionic Stimulants; Gastric Juice; Gastric Mucosa; Hexamethonium; Hexamethonium Compounds; Infusions, Parenteral; Male; Mecamylamine; Mucus; Nicotine; Rats; Rats, Sprague-Dawley | 1992 |
ATP receptor-mediated synaptic currents in the central nervous system.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Acetylcholine; Adenosine Triphosphate; Animals; Bicuculline; Brain; Chlorocebus aethiops; Evoked Potentials, Somatosensory; gamma-Aminobutyric Acid; Ganglionic Blockers; Glutamates; Glutamic Acid; Hexamethonium; Hexamethonium Compounds; In Vitro Techniques; Ion Channels; Kynurenic Acid; Mecamylamine; Quinoxalines; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Signal Transduction; Suramin; Tetrodotoxin | 1992 |
The effects of cholinergic drugs and cholinergic-rich foetal neural transplants on alcohol-induced deficits in radial maze performance in rats.
Topics: Acetylcholine; Alcohol Drinking; Alcoholism; Animals; Brain Mapping; Brain Tissue Transplantation; Cholinergic Fibers; Discrimination Learning; Ethanol; Fetal Tissue Transplantation; Ganglionic Blockers; Hexamethonium; Hexamethonium Compounds; Male; Mecamylamine; Mental Recall; Mesencephalon; N-Methylscopolamine; Nerve Regeneration; Nicotine; Norepinephrine; Orientation; Parasympatholytics; Rats; Rats, Inbred Strains; Receptors, Cholinergic; Retention, Psychology; Scopolamine; Scopolamine Derivatives | 1991 |
Effects of chronic and subchronic nicotine on tyrosine hydroxylase activity in noradrenergic and dopaminergic neurones in the rat brain.
Topics: Animals; Ataxia; Brain; Dopamine; Drug Administration Schedule; Hexamethonium; Hexamethonium Compounds; Injections, Subcutaneous; Male; Mecamylamine; Motor Activity; Neurons; Nicotine; Norepinephrine; Organ Specificity; Rats; Rats, Inbred Strains; Reference Values; Time Factors; Tyrosine 3-Monooxygenase | 1991 |
Effect of acute administration of nicotine on in vivo release of noradrenaline in the hippocampus of freely moving rats: a dose-response and antagonist study.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Behavior, Animal; Dopamine; Dose-Response Relationship, Drug; Hexamethonium; Hexamethonium Compounds; Hippocampus; Homovanillic Acid; Male; Mecamylamine; Nicotine; Norepinephrine; Rats; Rats, Inbred Strains | 1991 |
Effects of nicotinic agonists and antagonists on N-methyl-D-aspartate-induced 3H-norepinephrine release and 3H-(1-[1-(2-thienyl)cyclohexyl]-piperidine) binding in rat hippocampus.
Topics: Animals; Aspartic Acid; Carbachol; Dimethylphenylpiperazinium Iodide; Ganglionic Stimulants; Hexamethonium; Hexamethonium Compounds; Hippocampus; In Vitro Techniques; Mecamylamine; N-Methylaspartate; Nicotine; Norepinephrine; Rats; Receptors, Nicotinic | 1989 |
Hippocampal nicotinic cholinergic mechanisms mediate spontaneous alternation and fear during ontogenesis but not later in the rat.
Topics: Aging; Animals; Behavior, Animal; Cholinergic Fibers; Fear; Female; Hexamethonium; Hexamethonium Compounds; Hippocampus; Male; Mecamylamine; Rats; Rats, Inbred Strains; Receptors, Nicotinic | 1989 |
Mechanisms involved in the respiratory depressant actions of nicotine in anesthetized rats.
Topics: Anesthesia; Animals; Female; Hexamethonium; Hexamethonium Compounds; Mecamylamine; Naltrexone; Nicotine; Pentobarbital; Rats; Rats, Inbred Strains; Receptors, Nicotinic; Receptors, Opioid; Respiration; Urethane | 1989 |
Nicotine-induced tail-tremor and drug effects.
Topics: Animals; Arecoline; Atropine; Hexamethonium; Hexamethonium Compounds; Male; Mecamylamine; Nicotine; Physostigmine; Rats; Rats, Inbred Strains; Scopolamine; Tail; Tremor | 1989 |
Hypotensive actions of ketanserin in dogs: involvement of a centrally mediated inhibition of sympathetic vascular tone.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Dogs; Female; Heart Rate; Hexamethonium; Hexamethonium Compounds; Ketanserin; Male; Mecamylamine; Nicotine; Piperidines; Sympathetic Nervous System; Vascular Resistance; Vasomotor System | 1985 |
Nicotine-induced respiratory effects of cigarette smoke in dogs.
Topics: Animals; Blood; Bronchial Spasm; Dogs; Female; Hexamethonium; Hexamethonium Compounds; Male; Mecamylamine; Muscle Contraction; Nicotiana; Nicotine; Phrenic Nerve; Plants, Toxic; Respiration; Smoke; Trachea | 1985 |
The action of cholinomimetic and cholinolytic agents, hemicholinium-3 and alpha- and beta-bungarotoxin on the body wall muscle of the earthworm, Lumbricus terrestris.
Topics: Acetylcholine; Animals; Atropine; Bethanechol; Bethanechol Compounds; Bungarotoxins; Carbachol; Choline; Decamethonium Compounds; Gallamine Triethiodide; Hemicholinium 3; Hexamethonium; Hexamethonium Compounds; Mecamylamine; Muscles; Nicotine; Oligochaeta; Parasympatholytics; Parasympathomimetics; Physostigmine; Quaternary Ammonium Compounds; Receptors, Cholinergic; Succinylcholine; Tubocurarine | 1985 |
Inhibition by neosurugatoxin of nicotine-induced antinociception.
Topics: Animals; Central Nervous System; Hexamethonium; Hexamethonium Compounds; Male; Mecamylamine; Mice; Mollusk Venoms; Nicotine; Pain; Pempidine; Receptors, Nicotinic | 1986 |
Locomotor activity as a predictor of times and dosages for studies of nicotine's neurochemical actions.
Topics: Acetylcholine; Animals; Brain; Carbohydrate Metabolism; Dopamine; Dose-Response Relationship, Drug; Drug Administration Schedule; Hexamethonium; Hexamethonium Compounds; Injections, Intraperitoneal; Male; Mecamylamine; Mice; Motor Activity; Nicotine; Time Factors | 1987 |
Cholinergic function and alpha-bungarotoxin binding in PC12 cells.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Bungarotoxins; Carbachol; Dihydro-beta-Erythroidine; Hexamethonium; Hexamethonium Compounds; Ligands; Mecamylamine; Quaternary Ammonium Compounds; Receptors, Cholinergic; Receptors, Nicotinic; Sodium; Tubocurarine; Tumor Cells, Cultured | 1987 |
Nicotine enhances delayed matching-to-sample performance by primates.
Topics: Animals; Dose-Response Relationship, Drug; Hexamethonium; Hexamethonium Compounds; Macaca fascicularis; Mecamylamine; Memory; Mental Processes; Nicotine; Time Factors | 1988 |
Vasopressin modulates the activity of nicotinic cholinergic mechanisms during memory retrieval in mice.
Topics: Animals; Arginine Vasopressin; Atropine; Cholinergic Fibers; Hexamethonium; Hexamethonium Compounds; Lypressin; Male; Mecamylamine; Memory; Mice; Receptors, Muscarinic; Receptors, Nicotinic; Vasopressins | 1988 |
The blockage of ponto-geniculo-occipital waves in the cat lateral geniculate nucleus by nicotinic antagonists.
Topics: Action Potentials; Animals; Cats; Electric Stimulation; Evoked Potentials; Geniculate Bodies; Hexamethonium; Hexamethonium Compounds; Mecamylamine; Occipital Lobe; Optic Chiasm; Pons; Reference Values; Scopolamine | 1988 |
The effects of nicotine on locomotor activity in non-tolerant and tolerant rats.
Topics: Animals; Dose-Response Relationship, Drug; Drug Tolerance; Hexamethonium; Hexamethonium Compounds; Humans; Male; Mecamylamine; Motor Activity; Nicotine; Rats; Substance Withdrawal Syndrome | 1983 |
Cholinergic drugs and 4-aminopyridine alter hypoxic-induced behavioral deficits.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Arecoline; Atropine; Behavior, Animal; Cholinesterase Inhibitors; Drug Interactions; Hexamethonium; Hexamethonium Compounds; Hypoxia; Male; Mecamylamine; Mice; Motor Activity; Nicotine; Parasympathomimetics; Physostigmine; Structure-Activity Relationship | 1983 |
Nicotine cue in rats analysed with drugs acting on cholinergic and 5-hydroxytryptamine mechanisms.
Topics: Alkaloids; Animals; Azocines; Cues; Discrimination Learning; Dose-Response Relationship, Drug; Hexamethonium; Hexamethonium Compounds; Injections, Intraventricular; Male; Mecamylamine; Metergoline; Nicotine; Parasympatholytics; Quinolizines; Rats; Serotonin Antagonists | 1983 |
A study of the origin of altered pharmacological reactivity of synaptic structures caused by diabetes and pretreatment with contrainsular agents.
Topics: Animals; Cortisone; Diabetes Mellitus, Experimental; Female; Ganglia, Sympathetic; Hexamethonium; Hexamethonium Compounds; In Vitro Techniques; Mecamylamine; Motor Endplate; Neuromuscular Junction; Rats; Rats, Inbred Strains; Succinylcholine; Synapses; Tubocurarine | 1984 |
Efficacy and toxicity of drug combinations in treatment of physostigmine toxicosis.
Topics: Animals; Atropine; Benactyzine; Cholinesterase Reactivators; Diazepam; Drug Therapy, Combination; Ganglionic Blockers; Hexamethonium; Hexamethonium Compounds; Male; Mecamylamine; Mice; Physostigmine; Pralidoxime Compounds; Tranquilizing Agents; Trimedoxime | 1983 |
Differences of the electrical and nicotinic receptor stimulation-evoked liberation of norepinephrine from chicken sympathetic neurons in culture: possible involvement of different pools of the transmitter.
Topics: Action Potentials; Animals; Cells, Cultured; Chickens; Dimethylphenylpiperazinium Iodide; Electric Stimulation; Hexamethonium; Mecamylamine; Mollusk Venoms; Neurons; Norepinephrine; Receptors, Nicotinic; Stimulation, Chemical; Sympathetic Nervous System; Tetrodotoxin | 1995 |
Antagonists of cholinergic and serotonergic responses of Aplysia buccal muscle.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Acetylcholine; Animals; Aplysia; Atropine; Cholinergic Antagonists; Hexamethonium; In Vitro Techniques; Mecamylamine; Muscle Contraction; Muscle, Smooth; Piperazines; Pirenzepine; Serotonin Antagonists | 1994 |
Mecamylamine reverses physostigmine-induced attenuation of scopolamine-induced hyperactivity.
Topics: Animals; Hexamethonium; Hyperkinesis; Male; Mecamylamine; Motor Activity; Muscarinic Antagonists; Nicotine; Nicotinic Antagonists; Physostigmine; Rats; Rats, Wistar; Receptors, Muscarinic; Receptors, Nicotinic; Scopolamine | 1994 |
Desensitization of the nicotine-induced mesolimbic dopamine responses during constant infusion with nicotine.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Dopamine; Extracellular Space; Hexamethonium; Homovanillic Acid; Infusion Pumps, Implantable; Limbic System; Male; Mecamylamine; Microdialysis; Motor Activity; Nicotine; Rats; Rats, Sprague-Dawley | 1995 |
Nicotinic and muscarinic modulations of excitatory synaptic transmission in the rat prefrontal cortex in vitro.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Atropine; Bungarotoxins; Cerebral Cortex; Dimethylphenylpiperazinium Iodide; Electric Stimulation; Evoked Potentials; Hexamethonium; Hexamethonium Compounds; In Vitro Techniques; Male; Mecamylamine; Membrane Potentials; Muscarine; Neurons; Nicotine; Pirenzepine; Pyramidal Tracts; Quinoxalines; Rats; Rats, Sprague-Dawley; Scopolamine; Synaptic Transmission; Tubocurarine | 1993 |
Specific neurophysiological effects of systemic nicotine on neurons in the nucleus accumbens.
Topics: Action Potentials; Animals; Dopamine; Electric Stimulation; Haloperidol; Hexamethonium; Hexamethonium Compounds; Male; Mecamylamine; Morphine; Naloxone; Neurons; Nicotine; Nucleus Accumbens; Rats; Rats, Sprague-Dawley | 1993 |
Prevention of organophosphate intoxication with presynaptic cholinergic blockers.
Topics: Animals; Hemicholinium 3; Hexamethonium; Hexamethonium Compounds; Isoflurophate; Mecamylamine; Parasympatholytics; Poisoning; Rats; Rats, Sprague-Dawley; Trimethaphan | 1994 |
Interaction between 5-HT1A and nicotinic cholinergic receptors in the regulation of water maze navigation behavior.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Brain Chemistry; Fenclonine; Hexamethonium; Male; Maze Learning; Mecamylamine; Neurons; Nicotinic Antagonists; Presynaptic Terminals; Rats; Rats, Wistar; Receptors, Nicotinic; Receptors, Serotonin; Serotonin Antagonists; Space Perception | 1994 |
Characteristics of tail-tremor induced by nicotine in rats.
Topics: Animals; Haloperidol; Hexamethonium; Male; Mecamylamine; Motor Activity; Nicotine; Oxotremorine; Rats; Rats, Wistar; Tail; Tremor | 1994 |
Nicotine attenuates naloxone-induced jumping behaviour in morphine-dependent mice.
Topics: Animals; Atropine; Behavior, Animal; Benzazepines; Hexamethonium; Male; Mecamylamine; Mice; Morphine Dependence; Naloxone; Narcotic Antagonists; Nicotine; Phenoxybenzamine; Propranolol; Substance P; Substance Withdrawal Syndrome; Sulpiride | 1996 |
Central choline reverses hypotension caused by alpha-adrenoceptor or ganglion blockade in rats: the role of vasopressin.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Analysis of Variance; Animals; Blood Pressure; Choline; Dose-Response Relationship, Drug; Ganglionic Blockers; Heart Rate; Hexamethonium; Hypotension; Male; Mecamylamine; Nicotinic Antagonists; Nootropic Agents; Phentolamine; Propranolol; Rats; Vasoconstrictor Agents; Vasopressins | 1996 |
Effects of monoamine receptor antagonists on nicotine-induced hypophagia in the rat.
Topics: Adrenergic Antagonists; Animals; Anorexia; Atropine; Cholinergic Agents; Cholinergic Antagonists; Dopamine Antagonists; Eating; Hexamethonium; Male; Mecamylamine; Muscarinic Antagonists; Nicotine; Nicotinic Antagonists; Rats; Rats, Wistar; Receptors, Neurotransmitter; Serotonin Antagonists | 1997 |
Additive deficits in the choice accuracy of rats in the delayed non-matching to position task after cholinolytics and serotonergic lesions are non-mnemonic in nature.
Topics: 5,7-Dihydroxytryptamine; Animals; Brain; Hexamethonium; Male; Mecamylamine; Memory; Muscarinic Antagonists; Nicotinic Antagonists; Rats; Rats, Wistar; Scopolamine; Serotonin | 1997 |
Nicotinic receptor stimulation protects neurons against beta-amyloid toxicity.
Topics: Amyloid beta-Peptides; Animals; Benzylidene Compounds; Bungarotoxins; Cell Death; Cell Survival; Cells, Cultured; Cerebral Cortex; Fetus; Hexamethonium; Mecamylamine; Neurons; Neuroprotective Agents; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Peptide Fragments; Pyridines; Rats; Receptors, Nicotinic | 1997 |
Accumbal dopamine overflow after ethanol: localization of the antagonizing effect of mecamylamine.
Topics: Animals; Dopamine; Drug Antagonism; Ethanol; Hexamethonium; Male; Mecamylamine; Microdialysis; Nicotinic Antagonists; Nucleus Accumbens; Perfusion; Rats; Rats, Wistar; Receptors, Nicotinic; Ventral Tegmental Area | 1997 |
Nicotinic acetylcholine receptors of the neuronal type occur in the plasma membrane of sea urchin eggs.
Topics: Acetylcholine; Animals; Atropine; Bungarotoxins; Cell Membrane; Fertilization in Vitro; Hexamethonium; Mecamylamine; Membrane Potentials; Microelectrodes; Microscopy, Fluorescence; Muscarine; Muscarinic Agonists; Nicotine; Nicotinic Antagonists; Oocytes; Patch-Clamp Techniques; Receptors, Nicotinic; Sea Urchins; Sodium | 1997 |
Effect of indomethacin on nicotine-induced ACTH and corticosterone response.
Topics: Adrenocorticotropic Hormone; Animals; Corticosterone; Cyclooxygenase Inhibitors; Hexamethonium; Indomethacin; Male; Mecamylamine; Nicotine; Nicotinic Antagonists; Rats; Rats, Wistar | 1998 |
Antinociceptive effects of the novel neuronal nicotinic acetylcholine receptor agonist, ABT-594, in mice.
Topics: Analgesics, Non-Narcotic; Animals; Azetidines; Hexamethonium; Lethal Dose 50; Male; Maze Learning; Mecamylamine; Mice; Morphine; Motor Activity; Naltrexone; Narcotic Antagonists; Neurons; Nicotinic Agonists; Nicotinic Antagonists; Pain; Pyridines | 1998 |
Nicotine prevents glutamate-induced proteolysis of the microtubule-associated protein MAP-2 and glutamate neurotoxicity in primary cultures of cerebellar neurons.
Topics: Animals; Animals, Newborn; Calcium; Cell Survival; Cells, Cultured; Cerebellum; Excitatory Amino Acid Antagonists; Glutamic Acid; Hexamethonium; Kinetics; Mecamylamine; Microtubule-Associated Proteins; Neurons; Neurotoxins; Nicotine; Nicotinic Antagonists; Rats; Rats, Wistar; Tubulin | 1998 |
Single channel properties of human alpha3 AChRs: impact of beta2, beta4 and alpha5 subunits.
Topics: Animals; Brain Neoplasms; Electrophysiology; Hexamethonium; Humans; Kinetics; Mecamylamine; Neuroblastoma; Nicotinic Antagonists; Oocytes; Patch-Clamp Techniques; Radioimmunoassay; Receptors, Cholinergic; Tumor Cells, Cultured; Xenopus laevis | 1999 |
Effect of nicotine on apomorphine-induced licking behaviour in rats.
Topics: Animals; Apomorphine; Atropine; Cholinergic Antagonists; Dopamine Agonists; Drug Interactions; Hexamethonium; Injections, Intraperitoneal; Injections, Subcutaneous; Male; Mecamylamine; Muscarinic Antagonists; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Rats; Stereotyped Behavior | 1999 |
Role of the enteric nervous system in the fluid and electrolyte secretion of rotavirus diarrhea.
Topics: Animals; Animals, Newborn; Body Water; Diarrhea; Electrolytes; Enteric Nervous System; Hexamethonium; In Vitro Techniques; Intestinal Mucosa; Intestine, Small; Lidocaine; Mecamylamine; Mice; Mice, Inbred BALB C; Nicotinic Antagonists; Patch-Clamp Techniques; Rotavirus Infections; Synaptic Transmission; Tetrodotoxin; Theophylline | 2000 |
Nicotine induces disinhibitory behavior in the rat after subchronic peripheral nicotinic acetylcholine receptor blockade.
Topics: Animals; Behavior, Animal; Hexamethonium; Male; Maze Learning; Mecamylamine; Motor Activity; Nicotine; Nicotinic Antagonists; Peripheral Nervous System; Rats; Rats, Wistar; Receptors, Nicotinic | 2000 |
Receptor subtypes mediating depressor responses to microinjections of nicotine into medial NTS of the rat.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Anesthesia; Animals; Blood Pressure; Bungarotoxins; Calcium Channel Blockers; Conotoxins; Excitatory Amino Acid Antagonists; Glutamine; Heart Rate; Hexamethonium; Male; Mecamylamine; Microinjections; Nicotine; Nicotinic Antagonists; Rats; Rats, Wistar; Receptors, Nicotinic; Solitary Nucleus | 2000 |
Nicotine potentiates sulpiride-induced catalepsy in mice.
Topics: Animals; Antipsychotic Agents; Atropine; Catalepsy; Dose-Response Relationship, Drug; Drug Synergism; Hexamethonium; Male; Mecamylamine; Mice; Muscarinic Antagonists; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Sulpiride | 1998 |
Effect of nicotine on sniffing induced by dopaminergic receptor stimulation.
Topics: Amphetamine; Animals; Apomorphine; Behavior, Animal; Benzazepines; Dopamine Antagonists; Dose-Response Relationship, Drug; Hexamethonium; Humans; Male; Mecamylamine; Nicotine; Nicotinic Antagonists; Rats; Receptors, Dopamine; Smell; Sulpiride | 2000 |
Involvement of adrenergic and cholinergic systems in nicotine-induced anxiogenesis in mice.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Anxiety; Atropine; Clonidine; Hexamethonium; Male; Mecamylamine; Mice; Muscarinic Antagonists; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Phenylephrine; Prazosin; Receptors, Adrenergic, alpha-1; Yohimbine | 2000 |
Individual differences in rat locomotor activity are diminished by nicotine through stimulation of central nicotinic acetylcholine receptors.
Topics: Animals; Hexamethonium; Individuality; Male; Mecamylamine; Motor Activity; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic | 2001 |
The possible cross-tolerance between morphine- and nicotine-induced hypothermia in mice.
Topics: Animals; Body Temperature; Drug Interactions; Drug Tolerance; Hexamethonium; Hypothermia, Induced; Male; Mecamylamine; Mice; Morphine; Naloxone; Narcotic Antagonists; Narcotics; Nicotine; Nicotinic Agonists; Nicotinic Antagonists | 2001 |
Nicotinic acetylcholine receptor ligands differently affect cytochrome oxidase in the Honeybee brain.
Topics: Animals; Bees; Brain; Bungarotoxins; Electron Transport Complex IV; Hexamethonium; Mecamylamine; Mental Recall; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Receptors, Nicotinic | 2001 |
Nicotinic receptors involved in gastric noradrenaline release evoked by electrical stimulation of the splanchnic nerve in rats.
Topics: Animals; Atropine; Bungarotoxins; Calcium Channel Blockers; Conotoxins; Dihydro-beta-Erythroidine; Diltiazem; Electric Stimulation; Gastric Mucosa; Hexamethonium; In Vitro Techniques; Male; Mecamylamine; Nicotine; Norepinephrine; Rats; Rats, Wistar; Receptors, Nicotinic; Splanchnic Nerves; Stomach | 2001 |
Alpha4beta2 nicotinic acetylcholine receptor activation ameliorates impairment of spontaneous alternation behavior in stroke-prone spontaneously hypertensive rats, an animal model of attention deficit hyperactivity disorder.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Attention Deficit Disorder with Hyperactivity; Behavior, Animal; Central Nervous System Agents; Dihydro-beta-Erythroidine; Dose-Response Relationship, Drug; Hexamethonium; Hypertension; Mecamylamine; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Peripheral Nervous System; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Nicotinic | 2002 |
[Difference in action sites between mecamylamine and hexamethonium on nicotinic receptors of sympathetic neurons].
Topics: Animals; Animals, Newborn; Cells, Cultured; Hexamethonium; Mecamylamine; Neurons; Nicotinic Antagonists; Patch-Clamp Techniques; Rats; Rats, Wistar; Receptors, Nicotinic; Superior Cervical Ganglion | 2002 |
The effect of walking on regional blood flow and acetylcholine in the hippocampus in conscious rats.
Topics: Acetylcholine; Animals; Arginine; Atropine; Blood Pressure; Cerebrovascular Circulation; Enzyme Inhibitors; Extracellular Space; Hexamethonium; Hippocampus; Laser-Doppler Flowmetry; Male; Mecamylamine; Muscarinic Antagonists; NG-Nitroarginine Methyl Ester; Nicotinic Antagonists; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Wistar; Receptors, Cholinergic; Time Factors; Walking | 2003 |
Nicotine-induced inflammatory decreasing effect on passive skin arthus reaction in paraventricular nucleus-lesioned wistar rats.
Topics: Animals; Arthus Reaction; Corticosterone; Cycloheximide; Dose-Response Relationship, Drug; Hexamethonium; Injections, Intraperitoneal; Injections, Subcutaneous; Male; Mecamylamine; Mifepristone; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Paraventricular Hypothalamic Nucleus; Rabbits; Rats; Rats, Wistar; Skin; Time Factors | 2003 |
EFFECT OF SOME BLOCKING DRUGS ON THE PRESSOR RESPONSE TO PHYSOSTIGMINE IN THE RAT.
Topics: Atropine; Blood Pressure; Bretylium Compounds; Chlorpromazine; Choline; Epinephrine; Guanethidine; Hexamethonium; Hexamethonium Compounds; Mecamylamine; Morphine; Norepinephrine; Pharmacology; Physostigmine; Rats; Research; Vasoconstrictor Agents | 1963 |
THE SYMPATHETIC POSTGANGLIONIC FIBRE AND THE BLOCK BY BRETYLIUM; THE BLOCK PREVENTED BY HEXAMETHONIUM AND IMITATED BY MECAMYLAMINE.
Topics: Acetylcholine; Animals; Atropine; Autonomic Nerve Block; Biphenyl Compounds; Bretylium Compounds; Ganglionic Blockers; Hexamethonium; Hexamethonium Compounds; Mecamylamine; Pempidine; Pentolinium Tartrate; Pharmacology; Rabbits; Research; Sympathetic Fibers, Postganglionic; Sympathetic Nervous System | 1964 |
Unique mechanism of action of Alzheimer's drugs on brain nicotinic acetylcholine receptors and NMDA receptors.
Topics: Acetylcholine; Aconitine; Alzheimer Disease; Animals; Brain Chemistry; Bungarotoxins; Dihydro-beta-Erythroidine; Female; GTP-Binding Proteins; Hexamethonium; Mecamylamine; Nicotinic Agonists; Nicotinic Antagonists; Nootropic Agents; Patch-Clamp Techniques; Pregnancy; Protein Kinases; Pyrrolidinones; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Nicotinic | 2003 |
Endogenous ouabain-like factor (OLF) secretion is modulated by nicotinic mechanisms in rat adrenocortical cells.
Topics: Acetylcholine; Aconitine; Adrenal Cortex; Animals; Cardenolides; Digoxin; Dose-Response Relationship, Drug; Drug Synergism; Hexamethonium; Male; Mecamylamine; Nicotine; Nicotinic Antagonists; Physostigmine; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic; Saponins | 2004 |
Nicotine serves as a feature-positive modulator of Pavlovian appetitive conditioning in rats.
Topics: Animals; Appetitive Behavior; Choice Behavior; Conditioning, Classical; Discrimination Learning; Discrimination, Psychological; Dose-Response Relationship, Drug; Drug Administration Schedule; Hexamethonium; Male; Mecamylamine; Naloxone; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Rats; Rats, Sprague-Dawley; Reward | 2004 |
Modulation of cerebral microvascular permeability by endothelial nicotinic acetylcholine receptors.
Topics: Animals; Blood-Brain Barrier; Brain; Capillary Permeability; Endothelium, Vascular; Female; Hexamethonium; Mecamylamine; Microcirculation; Microscopy, Fluorescence; Nicotine; Nicotinic Antagonists; Protein Isoforms; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic | 2005 |
Characterization of nicotine's ability to serve as a negative feature in a Pavlovian appetitive conditioning task in rats.
Topics: Amphetamine; Animals; Arecoline; Association Learning; Bupropion; Caffeine; Chlordiazepoxide; Conditioning, Classical; Conditioning, Operant; Discrimination Learning; Dose-Response Relationship, Drug; Drug Interactions; Hexamethonium; Male; Mecamylamine; Motor Activity; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic; Reinforcement, Psychology; Sucrose | 2006 |
Intravenous nicotine self-administration in rats: effects of mecamylamine, hexamethonium and naloxone.
Topics: Animals; Association Learning; Brain; Conditioning, Operant; Disease Models, Animal; Dose-Response Relationship, Drug; Hexamethonium; Humans; Infusions, Intravenous; Male; Mecamylamine; Naloxone; Nicotine; Nicotinic Antagonists; Rats; Rats, Long-Evans; Receptors, Nicotinic; Receptors, Opioid; Reinforcement Schedule | 2006 |
Interaction of lobeline and nicotinic receptor ligands with the discriminative stimulus properties of cocaine and amphetamine.
Topics: Amphetamine; Animals; Cocaine; Discrimination, Psychological; Hexamethonium; Ligands; Lobeline; Male; Mecamylamine; Narcotics; Nicotinic Agonists; Nicotinic Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic; Reinforcement, Psychology | 2006 |
Antinociceptive effects of the novel spirocyclopiperazinium salt compound LXM-10 in mice.
Topics: Analgesics; Animals; Atropine; Atropine Derivatives; Body Temperature; Drug Evaluation, Preclinical; Female; Hexamethonium; Male; Mecamylamine; Mice; Mice, Inbred ICR; Motor Activity; Naloxone; Pain; Pain Measurement; Piperazines; Psychomotor Performance; Receptors, Adrenergic, alpha-2; Receptors, Muscarinic; Receptors, Nicotinic; Receptors, Opioid; Yohimbine | 2007 |
Peripheral administration of CDP-choline, phosphocholine or choline increases plasma adrenaline and noradrenaline concentrations.
Topics: Adrenal Glands; Animals; Atropine Derivatives; Autonomic Nervous System; Central Nervous System; Choline; Cytidine; Cytidine Diphosphate Choline; Cytidine Monophosphate; Disease Models, Animal; Dose-Response Relationship, Drug; Epinephrine; Female; Hemorrhage; Hexamethonium; Injections, Intraperitoneal; Injections, Intraventricular; Mecamylamine; Nicotinic Antagonists; Norepinephrine; Phosphorylcholine; Rats; Rats, Wistar; Time Factors | 2008 |
Activation and inhibition of mouse muscle and neuronal nicotinic acetylcholine receptors expressed in Xenopus oocytes.
Topics: Acetylcholine; Alkaloids; Animals; Azocines; Benzazepines; Decamethonium Compounds; Dihydro-beta-Erythroidine; Dose-Response Relationship, Drug; Electrophysiology; Gene Expression; Hexamethonium; Humans; Mecamylamine; Mice; Mice, Transgenic; Muscle, Skeletal; Nicotinic Antagonists; Oocytes; Quinolizines; Quinoxalines; Rats; Receptors, Nicotinic; Varenicline; Xenopus laevis | 2010 |
Nicotine's enhancing effects on responding maintained by conditioned reinforcers are reduced by pretreatment with mecamylamine, but not hexamethonium, in rats.
Topics: Animals; Conditioning, Operant; Discrimination Learning; Dose-Response Relationship, Drug; Extinction, Psychological; Hexamethonium; Male; Mecamylamine; Motivation; Nicotine; Nicotinic Antagonists; Rats; Rats, Long-Evans; Reinforcement, Psychology | 2010 |
Blockade of central nicotine acetylcholine receptor signaling attenuate ghrelin-induced food intake in rodents.
Topics: Analysis of Variance; Animals; Choline O-Acetyltransferase; Conditioning, Operant; Drug Administration Routes; Drug Interactions; Eating; Fasting; Food Preferences; Ghrelin; Hexamethonium; Male; Mecamylamine; Mice; Mice, Transgenic; Neurons; Nicotinic Antagonists; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Receptors, Ghrelin; Receptors, Nicotinic; Signal Transduction; Ventral Tegmental Area | 2010 |
Neuronal nicotinic receptor antagonist reduces anxiety-like behavior in mice.
Topics: Animals; Anti-Anxiety Agents; Anxiety; Blood-Brain Barrier; Brain; Exploratory Behavior; Hexamethonium; Lobeline; Mecamylamine; Mice; Mice, Inbred C57BL; Nicotinic Agonists; Nicotinic Antagonists; Receptors, Nicotinic | 2011 |
Varenicline blocks β2*-nAChR-mediated response and activates β4*-nAChR-mediated responses in mice in vivo.
Topics: Animals; Benzazepines; Dose-Response Relationship, Drug; Female; Genotype; Hexamethonium; Hypothermia; Inhibitory Concentration 50; Male; Mecamylamine; Mice; Mice, Inbred C57BL; Motor Activity; Mutation; Nerve Tissue Proteins; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Ondansetron; Quinoxalines; Receptors, Nicotinic; Receptors, Serotonin, 5-HT3; Varenicline | 2012 |
Postnatal changes in vagal control of esophageal muscle contractions in rats.
Topics: Acetylcholine; Animals; Animals, Newborn; Atropine; Electric Stimulation; Esophagus; Female; Ganglionic Blockers; Heart; Hexamethonium; Mecamylamine; Muscarinic Antagonists; Muscle Contraction; Muscle, Skeletal; Nicotinic Antagonists; Pregnancy; Protein Subunits; Rats; Rats, Wistar; Receptors, Nicotinic; Tubocurarine; Vagus Nerve | 2012 |
Acetylcholine-evoked afterdischarge in Aplysia bag cell neurons.
Topics: Acetylcholine; Action Potentials; Animals; Aplysia; Cells, Cultured; Conotoxins; Hexamethonium; Mecamylamine; Membrane Potentials; Neurons; Nicotinic Agonists; Synapses | 2012 |
Reduction in sympathetic nerve activity as a possible mechanism for the hypothermic effect of oseltamivir, an anti-influenza virus drug, in normal mice.
Topics: Animals; Antiviral Agents; Body Temperature; Hexamethonium; Hypothermia; Injections, Intraperitoneal; Injections, Intraventricular; Male; Mecamylamine; Mice; Neuraminidase; Nicotine; Oseltamivir; Zanamivir | 2013 |
Melatonin inhibits alcohol-induced increases in duodenal mucosal permeability in rats in vivo.
Topics: Animals; Duodenum; Ethanol; Hexamethonium; Intestinal Mucosa; Male; Mecamylamine; Melatonin; Nicotinic Antagonists; Permeability; Rats; Rats, Sprague-Dawley; Receptors, Melatonin; Tryptamines; Wine | 2013 |
A potentially novel nicotinic receptor in Aplysia neuroendocrine cells.
Topics: Acetylcholine; Aconitine; Action Potentials; Animals; Aplysia; Conotoxins; Dihydro-beta-Erythroidine; Hexamethonium; Mecamylamine; Neuroendocrine Cells; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Receptors, Nicotinic; Strychnine; Transcriptome | 2014 |
Artemin growth factor increases nicotinic cholinergic receptor subunit expression and activity in nociceptive sensory neurons.
Topics: Animals; Female; Ganglia, Spinal; Gene Expression Regulation; Glial Cell Line-Derived Neurotrophic Factor Receptors; Hexamethonium; Hyperalgesia; Male; Mecamylamine; Membrane Potentials; Mice; Mice, Inbred C57BL; Mice, Transgenic; Nerve Tissue Proteins; Nicotinic Antagonists; Nociceptors; Protein Subunits; Receptors, Nicotinic; Skin; Trigeminal Ganglion | 2014 |
5-HT
Topics: Acetylcholine; Animals; Benzofurans; Colon; Deoxyadenine Nucleotides; Electric Stimulation; Gastric Fundus; Gastrointestinal Tract; Guanethidine; Hexamethonium; Jejunum; Male; Mecamylamine; Mice, Inbred C57BL; Muscle Contraction; Muscle, Smooth; NG-Nitroarginine Methyl Ester; Receptors, Serotonin, 5-HT4; Serotonin 5-HT4 Receptor Agonists; Synaptic Transmission | 2017 |
Anti-cholinergics mecamylamine and scopolamine alleviate motion sickness-induced gastrointestinal symptoms through both peripheral and central actions.
Topics: Animals; Behavior, Animal; Cats; Cholinergic Antagonists; Hexamethonium; Hypothermia, Induced; Male; Mecamylamine; Models, Animal; Motion Sickness; Muscarinic Antagonists; Nausea; Neurons; Nicotinic Antagonists; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Scopolamine; Selenocysteine; Vomiting | 2019 |