mecamylamine has been researched along with cocaine in 48 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 16 (33.33) | 18.7374 |
| 1990's | 4 (8.33) | 18.2507 |
| 2000's | 12 (25.00) | 29.6817 |
| 2010's | 16 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bleich, S; Gulbins, E; Kornhuber, J; Reichel, M; Terfloth, L; Tripal, P; Wiltfang, J | 1 |
| Cox, BM; Izenwasser, S; Jacocks, HM; Rosenberger, JG | 1 |
| Goldenberg, MM | 1 |
| Gascon, AL; Walaszek, EJ | 1 |
| Ulrich, K | 1 |
| Akubue, PI | 1 |
| Gokhale, SD; Gulati, OD; Panchal, DI | 1 |
| Funasaka, T | 1 |
| Koppanyi, T; Maling, HM | 1 |
| Brodie, DA | 1 |
| Capps, PA; Clarke, DE | 1 |
| Rosenblum, G; Rosenblum, I | 1 |
| Botting, JH; Turmer, AD | 1 |
| Garcha, HS; Kumar, R; Pratt, JA; Stolerman, IP | 1 |
| Goldberg, SR; Henningfield, JE; Risner, ME; Spealman, RD | 1 |
| Ceña, V; García, AG; Montiel, C; Sánchez-García, P | 1 |
| Goldberg, SR; Risner, ME | 1 |
| Goldberg, SR; Spealman, RD | 1 |
| Abood, LG; Carroll, FI; Lerner-Marmarosh, N | 1 |
| Bedingfield, JB; Calder, LD; Karler, R | 1 |
| Gasior, M; Goldberg, SR; Jaszyna, M; Shoaib, M; Yasar, S | 1 |
| Costa, E; Javaid, JI; Lecca, D; Shim, I | 1 |
| Gallivan, C; Gross, R; Levin, ED; Mead, T; Rezvani, AH; Rose, JE | 1 |
| De Vries, TJ; Schoffelmeer, AN; van de Ven, HW; Vanderschuren, LJ; Wardeh, G | 1 |
| Barber, DJ; Desai, RI; Terry, P | 1 |
| Markou, A; Paterson, NE | 1 |
| Cunningham, CS; Jany, JR; Miller, DK; Polston, JE; Segert, IL | 1 |
| Angrist, B; Baker, SA; Elkashef, A; Leiderman, D; Majewska, D; Montgomery, A; O'leary, S; Reid, MS; Robinson, J; Rotrosen, J; Schwartz, M; Stone, J | 1 |
| Changeux, JP; de Kerchove D'Exaerde, A; Picciotto, MR; Zanardi, A; Zanetti, L; Zoli, M | 1 |
| Hansen, ST; Mark, GP | 1 |
| De Biasi, M; Gangitano, D; Main, A; Salas, R | 1 |
| Wang, B; Wise, RA; You, ZB; Zitzman, D | 1 |
| Hashim, A; Lajtha, A; Sershen, H | 1 |
| Bordia, T; Campos, C; McIntosh, JM; Quik, M | 1 |
| Bardo, MT; Neugebauer, NM; Stairs, DJ | 1 |
| Ding, JB; Goldberg, JA; Guzman, JN; Peterson, JD; Surmeier, DJ | 1 |
| Castelli, MP; Ennas, MG; Lecca, S; Luchicchi, A; Melis, M; Muntoni, AL; Pistis, M | 1 |
| Czoty, PW; Gould, RW; Nader, MA; Nader, SH | 1 |
| Markou, A; Olivier, B; Stoker, AK | 1 |
| Cunningham, CS; Javors, MA; McMahon, LR | 1 |
| Damaj, MI; Ignatowska-Jankowska, BM; Lichtman, AH; Muldoon, PP | 1 |
| Addy, NA; Behrens, S; Mason, GF; Solecki, W; Wang, J; Wickham, RJ; Zwerling, B | 1 |
| Fowler, JC; Froeliger, B; Lee, TH; Szabo, ST | 1 |
| Ide, S; Kaneda, K; Kihara, Y; Minami, M; Shinohara, F | 1 |
| Banks, ML | 1 |
| Banks, ML; Negus, SS; Poklis, JL; Schwienteck, KL | 1 |
| de Moura, FB; McMahon, LR | 2 |
1 trial(s) available for mecamylamine and cocaine
| Article | Year |
|---|---|
A placebo controlled, double-blind study of mecamylamine treatment for cocaine dependence in patients enrolled in an opiate replacement program.
Topics: Administration, Cutaneous; Cocaine; Cocaine-Related Disorders; Double-Blind Method; Drug Evaluation, Preclinical; Female; Humans; Male; Mecamylamine; Methadone; Methadyl Acetate; Narcotics; New York City; Nicotinic Antagonists; Treatment Outcome; Urban Population | 2005 |
47 other study(ies) available for mecamylamine and cocaine
| Article | Year |
|---|---|
Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model.
Topics: Algorithms; Animals; Cell Line; Cell Line, Tumor; Chemical Phenomena; Chemistry, Physical; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Molecular Conformation; Quantitative Structure-Activity Relationship; Rats; Sphingomyelin Phosphodiesterase | 2008 |
Nicotine indirectly inhibits [3H]dopamine uptake at concentrations that do not directly promote [3H]dopamine release in rat striatum.
Topics: Animals; Binding, Competitive; Carbachol; Chlorisondamine; Cocaine; Corpus Striatum; Dimethylphenylpiperazinium Iodide; Dopamine; Dose-Response Relationship, Drug; Male; Mecamylamine; Nicotine; Piperazines; Rats; Rats, Inbred Strains; Receptors, Nicotinic; Synaptosomes | 1991 |
Angiotensin in the analysis of the intrinsic nerve supply of isolated intestines.
Topics: Angiotensin II; Animals; Atropine; Cocaine; Epinephrine; Gerbillinae; Hexamethonium Compounds; Ileum; Intestines; Mecamylamine; Mice; Morphine; Motor Neurons; Muscle Contraction; Muscle, Smooth; Papaverine; Pentolinium Tartrate; Procaine; Rats | 1968 |
Mechanism of the musculotropic activity of angiotensin on the isolated guinea-pig seminal vsecile.
Topics: Acetylcholine; Angiotensin II; Animals; Atropine; Catecholamines; Cocaine; Epinephrine; Guanethidine; Guinea Pigs; Male; Mecamylamine; Muscle Contraction; Muscle, Smooth; Nicotine; Phentolamine; Piperazines; Seminal Vesicles; Tachyphylaxis; Tetracaine; Tyramine | 1968 |
A direct and an indirect action of 5-hydroxytryptamine on the distal part of the isolated colon of the rat.
Topics: Acetylcholine; Animals; Cholinesterase Inhibitors; Cocaine; Colon; Hexamethonium Compounds; Histamine; Lysergic Acid Diethylamide; Male; Mecamylamine; Muscle Contraction; Muscle, Smooth; Nicotine; Piperazines; Procaine; Rats; Scopolamine; Serotonin | 1965 |
The site of action of drugs on the isolated taenia caeci from the guinea-pig.
Topics: Acetylcholine; Animals; Cecum; Cocaine; Female; Guinea Pigs; Hexamethonium Compounds; Histamine; Histamine H1 Antagonists; In Vitro Techniques; Insecticides; Lysergic Acid Diethylamide; Male; Mecamylamine; Morphine; Muscle Contraction; Nicotine; Piperazines; Procaine; Scopolamine; Serotonin; Sympathomimetics | 1966 |
An analysis of the sympathomimetic effects of acetylcholine of the rat ileum.
Topics: Acetylcholine; Amphetamine; Animals; Bretylium Compounds; Choline; Cocaine; Dextroamphetamine; Drug Synergism; Epinephrine; Ethanolamines; Female; Guanethidine; Hexamethonium Compounds; Ileum; In Vitro Techniques; Male; Mecamylamine; Muscle Contraction; Muscle, Smooth; Nicotine; Pempidine; Phentolamine; Rats; Reserpine; Scopolamine; Xylenes | 1967 |
[Mechanism of contraction caused by nicotine on the isolated rabbit aorta, with reference to catecholamine release].
Topics: Animals; Aorta; Autonomic Agents; Bis-Trimethylammonium Compounds; Bretylium Compounds; Catecholamines; Cocaine; Edetic Acid; Ergotamine; Guanethidine; Hexamethonium Compounds; Hydrazines; In Vitro Techniques; Mecamylamine; Muscle Contraction; Nicotine; Norepinephrine; Pyrogallol; Rabbits; Reserpine; Tyramine; Yohimbine | 1967 |
Salivation in mice as an index of adrenergic activity. 3. Partial temperature-dependence of adrenergic drug effects.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Amino Alcohols; Animals; Atropine; Body Temperature; Chlorisondamine; Cocaine; Cresols; Dextroamphetamine; Epinephrine; Isoproterenol; Male; Mecamylamine; Methacholine Compounds; Mice; Mice, Inbred Strains; Norepinephrine; Pempidine; Phentolamine; Pilocarpine; Propranolol; Propylamines; Sympatholytics; Temperature | 1972 |
The mechanism of gastric hyperacidity produced by pylorus ligation in the rat.
Topics: Animals; Atropine; Cocaine; Duodenum; Gastric Acid; Gastric Acidity Determination; Gastric Fistula; Gastric Mucosa; Ligation; Male; Mecamylamine; Pylorus; Rats; Vagotomy | 1966 |
The effect of mecamylamine and pempidine on postganglionic sympathetic nerves.
Topics: Animals; Autonomic Fibers, Postganglionic; Bretylium Compounds; Cocaine; Depression, Chemical; Dextroamphetamine; Drug Interactions; Electric Stimulation; Ileum; In Vitro Techniques; Mecamylamine; Muscle Contraction; Neural Inhibition; Pempidine; Rabbits | 1972 |
Cardiovascular responses to cyclohexylamine.
Topics: Amines; Animals; Blood Pressure; Bradycardia; Cardiovascular System; Cats; Cocaine; Cyclohexanes; Female; Heart; Heart Rate; Hypertension; Iproniazid; Male; Mecamylamine; Norepinephrine; Phenoxybenzamine; Propranolol; Reserpine; Sensory Receptor Cells; Sweetening Agents; Sympathetic Nervous System; Tachycardia; Tachyphylaxis | 1968 |
Mode of action of vasopressin on isolated proximal colon of the guinea-pig.
Topics: Acetylcholine; Animals; Calcium; Carbachol; Cocaine; Cold Temperature; Colon; Guinea Pigs; Hexamethonium Compounds; Histamine; Hypoxia; In Vitro Techniques; Mecamylamine; Morphine; Muscle Contraction; Nicotine; Pentolinium Tartrate; Procaine; Scopolamine; Serotonin; Tetraethylammonium Compounds; Vasopressins | 1966 |
Role of training dose in discrimination of nicotine and related compounds by rats.
Topics: Alkaloids; Anabasine; Animals; Apomorphine; Azocines; Chlordiazepoxide; Cocaine; Discrimination, Psychological; Ganglionic Stimulants; Hexamethonium Compounds; Male; Mecamylamine; Nicotine; Oxotremorine; Picrotoxin; Quinolizines; Quipazine; Rats | 1984 |
Control of behavior by intravenous nicotine injections in laboratory animals.
Topics: Animals; Behavior, Animal; Cocaine; Dogs; Dose-Response Relationship, Drug; Female; Injections, Intravenous; Male; Mecamylamine; Nicotine; Reinforcement Schedule; Saimiri; Smoking; Species Specificity | 1983 |
Uptake of [3H]-nicotine and [3H]-noradrenaline by cultured chromaffin cells.
Topics: Adrenal Medulla; Animals; Cattle; Cell Membrane; Cells, Cultured; Chromaffin System; Cocaine; Imipramine; Mecamylamine; Nicotine; Norepinephrine; Tetracaine | 1984 |
A comparison of nicotine and cocaine self-administration in the dog: fixed-ratio and progressive-ratio schedules of intravenous drug infusion.
Topics: Animals; Body Temperature; Cocaine; Conditioning, Operant; Dogs; Female; Heart Rate; Infusions, Parenteral; Male; Mecamylamine; Nicotine; Pupil; Self Administration | 1983 |
Maintenance of schedule-controlled behavior by intravenous injections of nicotine in squirrel monkeys.
Topics: Animals; Behavior, Animal; Cocaine; Drug Administration Schedule; Injections, Intravenous; Male; Mecamylamine; Nicotine; Saimiri | 1982 |
Antagonism of nicotine's action by cocaine analogs.
Topics: Animals; Brain; Cattle; Cocaine; Mecamylamine; Mice; Nicotine; Quinuclidinyl Benzilate; Structure-Activity Relationship | 1995 |
A novel nicotinic-cholinergic role in behavioral sensitization to amphetamine-induced stereotypy in mice.
Topics: Acetylcholine; Amphetamine; Animals; Atropine; Cholinergic Antagonists; Cocaine; Dihydro-beta-Erythroidine; Dopamine Uptake Inhibitors; Male; Mecamylamine; Mice; Mice, Inbred Strains; Muscarinic Antagonists; Nicotinic Antagonists; Stereotyped Behavior | 1996 |
Acquisition of nicotine discrimination and discriminative stimulus effects of nicotine in rats chronically exposed to caffeine.
Topics: Amphetamine; Analysis of Variance; Animals; Caffeine; Cocaine; Discrimination Learning; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Male; Mecamylamine; Nicotine; Nicotinic Antagonists; Piperazines; Rats; Rats, Sprague-Dawley; Stimulation, Chemical; Thiazepines | 1999 |
Striatal application of nicotine, but not of lobeline, attenuates dopamine release in freely moving rats.
Topics: Aconitine; Animals; Cocaine; Corpus Striatum; Dopamine; Kinetics; Lobeline; Male; Mecamylamine; Microdialysis; Nerve Endings; Nicotine; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic | 2000 |
The nicotinic antagonist mecamylamine preferentially inhibits cocaine vs. food self-administration in rats.
Topics: Animals; Cocaine; Conditioning, Operant; Dopamine Uptake Inhibitors; Eating; Female; Food; Mecamylamine; Nicotinic Antagonists; Rats; Rats, Sprague-Dawley; Reinforcement, Psychology; Self Administration | 2000 |
Psychostimulant-induced behavioral sensitization depends on nicotinic receptor activation.
Topics: Amphetamine; Amphetamine-Related Disorders; Animals; Association Learning; Behavior, Animal; Central Nervous System Stimulants; Cocaine; Cocaine-Related Disorders; Dopamine; Dopamine Uptake Inhibitors; In Vitro Techniques; Male; Mecamylamine; Motivation; Motor Activity; Neuronal Plasticity; Neurons; Nicotine; Nicotinic Antagonists; Nucleus Accumbens; Rats; Rats, Wistar; Receptors, Nicotinic | 2002 |
Dopaminergic and cholinergic involvement in the discriminative stimulus effects of nicotine and cocaine in rats.
Topics: Acetylcholine; Animals; Cholinergic Agonists; Cocaine; Conditioning, Operant; Discrimination, Psychological; Dopamine; Dopamine Antagonists; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Flupenthixol; Generalization, Stimulus; Male; Mecamylamine; Muscarinic Agonists; Nicotine; Nicotinic Antagonists; Pilocarpine; Rats; Rats, Sprague-Dawley | 2003 |
Prolonged nicotine dependence associated with extended access to nicotine self-administration in rats.
Topics: Analysis of Variance; Animals; Behavior, Animal; Cocaine; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug Administration Routes; Drug Administration Schedule; Ganglionic Stimulants; Male; Mecamylamine; Nicotine; Nicotinic Antagonists; Rats; Rats, Wistar; Self Administration; Substance Withdrawal Syndrome; Time Factors; Tobacco Use Disorder | 2004 |
Interaction of lobeline and nicotinic receptor ligands with the discriminative stimulus properties of cocaine and amphetamine.
Topics: Amphetamine; Animals; Cocaine; Discrimination, Psychological; Hexamethonium; Ligands; Lobeline; Male; Mecamylamine; Narcotics; Nicotinic Agonists; Nicotinic Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic; Reinforcement, Psychology | 2006 |
Inhibition of both alpha7* and beta2* nicotinic acetylcholine receptors is necessary to prevent development of sensitization to cocaine-elicited increases in extracellular dopamine levels in the ventral striatum.
Topics: Aconitine; alpha7 Nicotinic Acetylcholine Receptor; Animals; Basal Ganglia; Central Nervous System Stimulants; Cocaine; Dopamine; Extracellular Fluid; Male; Mecamylamine; Mice; Mice, Inbred C57BL; Mice, Knockout; Nicotinic Antagonists; Receptors, Nicotinic | 2006 |
The nicotinic acetylcholine receptor antagonist mecamylamine prevents escalation of cocaine self-administration in rats with extended daily access.
Topics: Analysis of Variance; Anesthetics, Local; Animals; Behavior, Addictive; Behavior, Animal; Cocaine; Drug Interactions; Infusions, Intravenous; Male; Mecamylamine; Nicotinic Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic; Self Administration; Time Factors | 2007 |
Decreased withdrawal symptoms but normal tolerance to nicotine in mice null for the alpha7 nicotinic acetylcholine receptor subunit.
Topics: Aconitine; alpha7 Nicotinic Acetylcholine Receptor; Analysis of Variance; Anesthetics, Local; Animals; Behavior, Animal; Cocaine; Disease Models, Animal; Drug Tolerance; Exploratory Behavior; Female; Male; Maze Learning; Mecamylamine; Mice; Mice, Inbred C57BL; Mice, Knockout; Nicotinic Antagonists; Receptors, Nicotinic; Substance Withdrawal Syndrome | 2007 |
Acetylcholine release in the mesocorticolimbic dopamine system during cocaine seeking: conditioned and unconditioned contributions to reward and motivation.
Topics: Acetylcholine; Analysis of Variance; Animals; Atropine; Behavior, Animal; Cholinergic Antagonists; Cocaine; Cocaine-Related Disorders; Conditioning, Psychological; Dopamine; Extinction, Psychological; Male; Mecamylamine; Microdialysis; Motivation; Rats; Rats, Long-Evans; Reward; Self Administration; Substantia Nigra; Ventral Tegmental Area | 2008 |
Differences between nicotine and cocaine-induced conditioned place preferences.
Topics: Adrenergic alpha-Antagonists; Animals; Atropine; Benzazepines; Cocaine; Conditioning, Classical; Dopamine Antagonists; Dopamine Uptake Inhibitors; Male; Mecamylamine; Mice; Mice, Inbred C57BL; Muscarinic Antagonists; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Phentolamine; Space Perception | 2010 |
Nicotinic receptor-mediated reduction in L-DOPA-induced dyskinesias may occur via desensitization.
Topics: Amphetamine; Animals; Antiparkinson Agents; Autoradiography; Behavior, Animal; Bridged Bicyclo Compounds, Heterocyclic; Calcium Channel Blockers; Central Nervous System Stimulants; Cocaine; Conotoxins; Dopamine Plasma Membrane Transport Proteins; Dyskinesia, Drug-Induced; Functional Laterality; Levodopa; Male; Mecamylamine; Neostriatum; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic; Stereotyped Behavior | 2010 |
Nicotine and cocaine self-administration using a multiple schedule of intravenous drug and sucrose reinforcement in rats.
Topics: Anesthetics, Local; Animals; Behavior, Animal; Benzazepines; Cocaine; Conditioning, Operant; Dopamine Antagonists; Dose-Response Relationship, Drug; Drug Administration Schedule; Extinction, Psychological; Food Preferences; Infusions, Intravenous; Male; Mecamylamine; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Rats; Rats, Sprague-Dawley; Reinforcement, Psychology; Self Administration; Sucrose | 2010 |
Thalamic gating of corticostriatal signaling by cholinergic interneurons.
Topics: Acetylcholine; Action Potentials; Amino Acids; Animals; Animals, Newborn; Cerebral Cortex; Choline O-Acetyltransferase; Cocaine; Corpus Striatum; Dopamine Antagonists; Dopamine Uptake Inhibitors; Electric Stimulation; Excitatory Postsynaptic Potentials; Green Fluorescent Proteins; In Vitro Techniques; Interneurons; Mecamylamine; Mice; Mice, Transgenic; Models, Biological; Neural Pathways; Nicotinic Antagonists; Patch-Clamp Techniques; Receptors, Dopamine D1; Receptors, Dopamine D2; Sulpiride; Synaptic Transmission; Thalamus; Time Factors | 2010 |
Effects of drugs of abuse on putative rostromedial tegmental neurons, inhibitory afferents to midbrain dopamine cells.
Topics: Action Potentials; Animals; Animals, Newborn; Behavior, Animal; Benzoxazines; Cocaine; Dopamine; Drug Interactions; Electric Stimulation; Excitatory Postsynaptic Potentials; Gene Expression Regulation; Illicit Drugs; In Vitro Techniques; Male; Mecamylamine; Morphine; Morpholines; Naloxone; Naphthalenes; Narcotic Antagonists; Neural Inhibition; Neural Pathways; Neurons; Nicotinic Antagonists; Patch-Clamp Techniques; Piperidines; Pyrazoles; Rats; Rats, Sprague-Dawley; Rimonabant; Time Factors; Ventral Tegmental Area | 2011 |
Effects of varenicline on the reinforcing and discriminative stimulus effects of cocaine in rhesus monkeys.
Topics: Animals; Benzazepines; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Discrimination Learning; Discrimination, Psychological; Dopamine Uptake Inhibitors; Macaca mulatta; Male; Mecamylamine; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Quinoxalines; Reinforcement, Psychology; Self Administration; Time Factors; Varenicline | 2011 |
Involvement of metabotropic glutamate receptor 5 in brain reward deficits associated with cocaine and nicotine withdrawal and somatic signs of nicotine withdrawal.
Topics: Anhedonia; Animals; Brain; Cocaine; Male; Mecamylamine; Mice; Mice, Inbred C57BL; Mice, Knockout; Nicotine; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Reward; Self Stimulation; Substance Withdrawal Syndrome; Time Factors | 2012 |
Pharmacologic characterization of a nicotine-discriminative stimulus in rhesus monkeys.
Topics: Alkaloids; Animals; Azocines; Benzazepines; Cocaine; Conditioning, Operant; Discrimination Learning; Dopamine Uptake Inhibitors; Drug Interactions; Female; Hypnotics and Sedatives; Macaca mulatta; Male; Mecamylamine; Midazolam; Nicotine; Nicotinic Agonists; Quinolizines; Quinoxalines; Receptors, Nicotinic; Varenicline | 2012 |
The cannabinoid CB2 receptor is necessary for nicotine-conditioned place preference, but not other behavioral effects of nicotine in mice.
Topics: Animals; Anisoles; Behavior, Animal; Cocaine; Conditioning, Psychological; Cyclohexanols; Dose-Response Relationship, Drug; Female; Male; Mecamylamine; Mice; Mice, Inbred C57BL; Mice, Knockout; Nicotine; Receptor, Cannabinoid, CB2; Reward; Substance Withdrawal Syndrome; Tobacco Use Disorder | 2013 |
Differential role of ventral tegmental area acetylcholine and N-methyl-D-aspartate receptors in cocaine-seeking.
Topics: Acetylcholine; Anesthetics, Local; Animals; Benzazepines; Cholinergic Antagonists; Cocaine; Cues; Dopamine; Dopamine Agonists; Drug-Seeking Behavior; Lidocaine; Male; Mecamylamine; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Scopolamine; Time Factors; Valine; Ventral Tegmental Area | 2013 |
Time-dependent changes in nicotine behavioral responsivity during early withdrawal from chronic cocaine administration and attenuation of cocaine sensitization by mecamylamine.
Topics: Animals; Cocaine; Dopamine Uptake Inhibitors; Male; Mecamylamine; Motor Activity; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Rats; Rats, Sprague-Dawley; Substance Withdrawal Syndrome | 2014 |
Critical role of cholinergic transmission from the laterodorsal tegmental nucleus to the ventral tegmental area in cocaine-induced place preference.
Topics: Acetylcholine; Animals; Carbachol; Cholinergic Agonists; Cocaine; Cocaine-Related Disorders; Conditioning, Classical; Dopamine Uptake Inhibitors; Male; Mecamylamine; Muscarinic Antagonists; Neural Pathways; Nicotinic Antagonists; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Scopolamine; Space Perception; Tegmentum Mesencephali; Ventral Tegmental Area | 2014 |
Effects of the nicotinic acetylcholine receptor antagonist mecamylamine on the discriminative stimulus effects of cocaine in male rhesus monkeys.
Topics: Animals; Cocaine; Discrimination Learning; Dose-Response Relationship, Drug; Macaca mulatta; Male; Mecamylamine; Nicotinic Antagonists; Receptors, Nicotinic | 2014 |
Effects of continuous nicotine treatment and subsequent termination on cocaine versus food choice in male rhesus monkeys.
Topics: Animals; Choice Behavior; Cocaine; Dose-Response Relationship, Drug; Food; Macaca mulatta; Male; Mecamylamine; Nicotine; Nicotinic Antagonists; Self Administration | 2015 |
Differential antagonism and tolerance/cross-tolerance among nicotinic acetylcholine receptor agonists: scheduled-controlled responding and hypothermia in C57BL/6J mice.
Topics: Animals; Cocaine; Conditioning, Operant; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Tolerance; Hyperthermia, Induced; Male; Mecamylamine; Mice; Mice, Inbred C57BL; Nicotinic Agonists; Nicotinic Antagonists; Reinforcement Schedule; Tobacco Use Disorder | 2016 |
The contribution of α4β2 and non-α4β2 nicotinic acetylcholine receptors to the discriminative stimulus effects of nicotine and varenicline in mice.
Topics: Aconitine; Alkaloids; alpha7 Nicotinic Acetylcholine Receptor; Animals; Azocines; Benzamides; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cocaine; Dihydro-beta-Erythroidine; Discrimination, Psychological; Dopamine Uptake Inhibitors; Hypnotics and Sedatives; Ibogaine; Male; Mecamylamine; Mice; Mice, Inbred C57BL; Midazolam; Nerve Tissue Proteins; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Pyridines; Quinolizines; Receptors, Nicotinic; Varenicline | 2017 |