mebendazole and paclitaxel

mebendazole has been researched along with paclitaxel in 16 studies

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19902 (12.50)18.7374
1990's0 (0.00)18.2507
2000's5 (31.25)29.6817
2010's9 (56.25)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Huang, L; Humphreys, JE; Morgan, JB; Polli, JW; Serabjit-Singh, CS; Webster, LO; Wring, SA1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Lombardo, F; Obach, RS; Waters, NJ1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Abou El-Magd, RM; Arakawa, K; Ayoub, AT; Chan, G; Glover, M; Klobukowski, M; Lewis, CW; Nindita, Y; Sun, L; Tilli, TM; Tuszynski, J; Xiao, J1
Cheong, JE; Chung, I; Jernigan, FE; Sun, L; Wang, Y; Xu, Y; Zaffagni, M; Zetter, BR1
Cappuccinelli, P; Juliano, C; Monaco, G; Rubino, S1
Bandiera, P; Cappuccinelli, P; Juliano, C; Monaco, G; Tedde, G1
Chada, S; Gomyo, Y; Mukhopadhyay, T; Ramesh, R; Roth, JA; Sasaki, J1
Čáňová, K; Hanušová, V; Knoppová, K; Králová, V; Skálová, L; Staňková, P1
Abdolahad, M; Amiri, MH; Gharooni, M; Khosravi, S; Namdar, N; Zanganeh, S1

Reviews

1 review(s) available for mebendazole and paclitaxel

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

15 other study(ies) available for mebendazole and paclitaxel

ArticleYear
Rational use of in vitro P-glycoprotein assays in drug discovery.
    The Journal of pharmacology and experimental therapeutics, 2001, Volume: 299, Issue:2

    Topics: Adenosine Triphosphatases; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cells, Cultured; Chromatography, Liquid; Enzyme Inhibitors; Fluoresceins; Fluorescent Dyes; Humans; Mass Spectrometry; Pharmacology; Spodoptera

2001
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Antitumor Activity of Lankacidin Group Antibiotics Is Due to Microtubule Stabilization via a Paclitaxel-like Mechanism.
    Journal of medicinal chemistry, 2016, Oct-27, Volume: 59, Issue:20

    Topics: Animals; Anti-Bacterial Agents; Antineoplastic Agents; Binding Sites; Brain; Cell Survival; Dose-Response Relationship, Drug; HeLa Cells; Humans; Macrolides; Microtubules; Molecular Conformation; Molecular Dynamics Simulation; Paclitaxel; Structure-Activity Relationship; Swine; Tubulin; Tumor Cells, Cultured

2016
Synthesis and anticancer activity of novel water soluble benzimidazole carbamates.
    European journal of medicinal chemistry, 2018, Jan-20, Volume: 144

    Topics: Animals; Antineoplastic Agents; Benzimidazoles; Carbamates; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Humans; Male; Mice; Molecular Docking Simulation; Molecular Structure; Neoplasms, Experimental; Solubility; Structure-Activity Relationship; Tumor Cells, Cultured; Water

2018
Inhibition of Trichomonas vaginalis replication by the microtubule stabilizer taxol.
    The Journal of protozoology, 1986, Volume: 33, Issue:2

    Topics: Alkaloids; Animals; Cytoskeleton; Fluorescent Antibody Technique; Mebendazole; Microscopy, Electron, Scanning; Microtubules; Mitotic Index; Paclitaxel; Trichomonas vaginalis

1986
Action of anticytoskeletal compounds on in vitro cytopathic effect, phagocytosis, and adhesiveness of Trichomonas vaginalis.
    Genitourinary medicine, 1987, Volume: 63, Issue:4

    Topics: Alkaloids; Animals; Bacterial Adhesion; Cells, Cultured; Colchicine; Cytochalasin B; Cytoskeleton; Fibroblasts; Griseofulvin; Mebendazole; Mice; Mice, Inbred Strains; Paclitaxel; Phagocytosis; Trichomonas vaginalis

1987
The anthelmintic drug mebendazole induces mitotic arrest and apoptosis by depolymerizing tubulin in non-small cell lung cancer cells.
    Molecular cancer therapeutics, 2002, Volume: 1, Issue:13

    Topics: Administration, Oral; Animals; Antinematodal Agents; Antineoplastic Agents, Phytogenic; Apoptosis; Biomarkers, Tumor; Blotting, Western; Carcinoma, Non-Small-Cell Lung; Caspases; Cell Cycle; Cytochrome c Group; Flow Cytometry; Humans; In Situ Nick-End Labeling; Lung Neoplasms; Mebendazole; Mice; Mice, Nude; Microscopy, Fluorescence; Mitochondria; Paclitaxel; Spindle Apparatus; Tubulin; Tumor Cells, Cultured

2002
Antiproliferative effect of benzimidazole anthelmintics albendazole, ricobendazole, and flubendazole in intestinal cancer cell lines.
    Anti-cancer drugs, 2013, Volume: 24, Issue:9

    Topics: Adenocarcinoma; Albendazole; Anthelmintics; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Cell Proliferation; Cell Survival; Drug Resistance, Neoplasm; Drug Synergism; G2 Phase; Humans; Inhibitory Concentration 50; Intestinal Neoplasms; Mebendazole; Microtubules; Paclitaxel; Protein Stability; Tubulin Modulators

2013
Electrochemical approach for monitoring the effect of anti tubulin drugs on breast cancer cells based on silicon nanograss electrodes.
    Analytica chimica acta, 2016, Sep-28, Volume: 938

    Topics: Breast Neoplasms; Electrodes; Female; Humans; MCF-7 Cells; Mebendazole; Nanotechnology; Paclitaxel; Silicon; Tubulin

2016