mebendazole and colchicine

mebendazole has been researched along with colchicine in 27 studies

Research

Studies (27)

TimeframeStudies, this research(%)All Research%
pre-19906 (22.22)18.7374
1990's6 (22.22)18.2507
2000's4 (14.81)29.6817
2010's9 (33.33)24.3611
2020's2 (7.41)2.80

Authors

AuthorsStudies
Huang, L; Humphreys, JE; Morgan, JB; Polli, JW; Serabjit-Singh, CS; Webster, LO; Wring, SA1
Lombardo, F; Obach, RS; Waters, NJ1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Abou El-Magd, RM; Arakawa, K; Ayoub, AT; Chan, G; Glover, M; Klobukowski, M; Lewis, CW; Nindita, Y; Sun, L; Tilli, TM; Tuszynski, J; Xiao, J1
Jadhav, A; Kerns, E; Nguyen, K; Shah, P; Sun, H; Xu, X; Yan, Z; Yu, KR1
Kabir, M; Kerns, E; Nguyen, K; Shah, P; Sun, H; Wang, Y; Xu, X; Yu, KR1
Kabir, M; Kerns, E; Neyra, J; Nguyen, K; Nguyễn, ÐT; Shah, P; Siramshetty, VB; Southall, N; Williams, J; Xu, X; Yu, KR1
Itkin, M; Kabir, M; Mathé, EA; Nguyễn, ÐT; Padilha, EC; Shah, P; Shinn, P; Siramshetty, V; Wang, AQ; Williams, J; Xu, X; Yu, KR; Zhao, T1
Tekwani, BL1
Casado-Escribano, N; Criado-Fornelio, A; De Armas-Serra, C; Díez, JC; Jiménez-González, A; Rodríguez-Caabeiro, F1
Lacey, E; Russell, GJ2
Bandiera, P; Cappuccinelli, P; Juliano, C; Monaco, G; Tedde, G1
Criado Fornelio, A; Jimenez Gonzalez, A; Rodriguez Caabeiro, F1
Lacey, E; Prichard, RK; Sangster, NC1
Delves, CJ; Howells, RE1
Bachmann, R; Köhler, P1
Elhajouji, A; Kirsch-Volders, M; Van Hummelen, P1
Elhajouji, A; Kirsch-Volders, M; Tibaldi, F1
Cunha, M; Elhajouji, A; Kirsch-Volders, M1
Kovar, P; Ng, SC; Rosenberg, SH; Tahir, SK1
Bairos, VA; Gonçalves, CA; Poiares-Da-Silva, J; Sousa, MC1

Reviews

2 review(s) available for mebendazole and colchicine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Using in vitro ADME data for lead compound selection: An emphasis on PAMPA pH 5 permeability and oral bioavailability.
    Bioorganic & medicinal chemistry, 2022, 02-15, Volume: 56

    Topics: Administration, Oral; Animals; Betamethasone; Biological Availability; Caco-2 Cells; Cell Membrane Permeability; Cells, Cultured; Dexamethasone; Dogs; Dose-Response Relationship, Drug; Humans; Hydrogen-Ion Concentration; Madin Darby Canine Kidney Cells; Mice; Molecular Structure; Neural Networks, Computer; Ranitidine; Rats; Structure-Activity Relationship; Verapamil

2022

Other Studies

25 other study(ies) available for mebendazole and colchicine

ArticleYear
Rational use of in vitro P-glycoprotein assays in drug discovery.
    The Journal of pharmacology and experimental therapeutics, 2001, Volume: 299, Issue:2

    Topics: Adenosine Triphosphatases; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cells, Cultured; Chromatography, Liquid; Enzyme Inhibitors; Fluoresceins; Fluorescent Dyes; Humans; Mass Spectrometry; Pharmacology; Spodoptera

2001
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Antitumor Activity of Lankacidin Group Antibiotics Is Due to Microtubule Stabilization via a Paclitaxel-like Mechanism.
    Journal of medicinal chemistry, 2016, Oct-27, Volume: 59, Issue:20

    Topics: Animals; Anti-Bacterial Agents; Antineoplastic Agents; Binding Sites; Brain; Cell Survival; Dose-Response Relationship, Drug; HeLa Cells; Humans; Macrolides; Microtubules; Molecular Conformation; Molecular Dynamics Simulation; Paclitaxel; Structure-Activity Relationship; Swine; Tubulin; Tumor Cells, Cultured

2016
Highly predictive and interpretable models for PAMPA permeability.
    Bioorganic & medicinal chemistry, 2017, 02-01, Volume: 25, Issue:3

    Topics: Artificial Intelligence; Caco-2 Cells; Cell Membrane Permeability; Humans; Models, Biological; Organic Chemicals; Regression Analysis; Support Vector Machine

2017
Predictive models of aqueous solubility of organic compounds built on A large dataset of high integrity.
    Bioorganic & medicinal chemistry, 2019, 07-15, Volume: 27, Issue:14

    Topics: Drug Discovery; Organic Chemicals; Pharmaceutical Preparations; Solubility

2019
Retrospective assessment of rat liver microsomal stability at NCATS: data and QSAR models.
    Scientific reports, 2020, 11-26, Volume: 10, Issue:1

    Topics: Animals; Computer Simulation; Databases, Factual; Drug Discovery; High-Throughput Screening Assays; Liver; Machine Learning; Male; Microsomes, Liver; National Center for Advancing Translational Sciences (U.S.); Pharmaceutical Preparations; Quantitative Structure-Activity Relationship; Rats; Rats, Sprague-Dawley; Retrospective Studies; United States

2020
Secretory cholinesterase of Ancylostoma ceylanicum: effect of tubulin binding agents and benzimidazole anthelmintics.
    Life sciences, 1992, Volume: 50, Issue:10

    Topics: Acetylcholinesterase; Albendazole; Ancylostoma; Animals; Anthelmintics; Colchicine; Mebendazole; Tubulin; Vinblastine

1992
Preliminary characterization and interaction of tubulin from Trichinella spiralis larvae with benzimidazole derivatives.
    Veterinary parasitology, 1991, Volume: 39, Issue:1-2

    Topics: Albendazole; Animals; Anthelmintics; Benzimidazoles; Binding, Competitive; Colchicine; Electrophoresis, Polyacrylamide Gel; Fenbendazole; Immunoblotting; Mebendazole; Trichinella; Tubulin

1991
Colchicine binding in the free-living nematode Caenorhabditis elegans.
    Biochimica et biophysica acta, 1989, Dec-08, Volume: 993, Issue:2-3

    Topics: Animals; Binding Sites; Brain; Caenorhabditis; Colchicine; Kinetics; Mebendazole; Podophyllotoxin; Sheep; Tubulin; Vinblastine

1989
Action of anticytoskeletal compounds on in vitro cytopathic effect, phagocytosis, and adhesiveness of Trichomonas vaginalis.
    Genitourinary medicine, 1987, Volume: 63, Issue:4

    Topics: Alkaloids; Animals; Bacterial Adhesion; Cells, Cultured; Colchicine; Cytochalasin B; Cytoskeleton; Fibroblasts; Griseofulvin; Mebendazole; Mice; Mice, Inbred Strains; Paclitaxel; Phagocytosis; Trichomonas vaginalis

1987
The mode of action of some benzimidazole drugs on Trichinella spiralis.
    Parasitology, 1987, Volume: 95 ( Pt 1)

    Topics: Animals; Colchicine; Glucose; Glycogen; Mebendazole; Mice; Proteins; Succinate Dehydrogenase; Thiabendazole; Trichinella; Trichinellosis

1987
Tubulin and benzimidazole-resistance in Trichostrongylus colubriformis (Nematoda).
    The Journal of parasitology, 1985, Volume: 71, Issue:5

    Topics: Acetylcholinesterase; Animals; Benzimidazoles; Colchicine; Drug Resistance; Mebendazole; Microscopy, Electron; Microtubules; Thiabendazole; Trichostrongylus; Tubulin

1985
A simple method for the identification of compounds which inhibit tubulin polymerization in filarial worms.
    Annals of tropical medicine and parasitology, 1985, Volume: 79, Issue:5

    Topics: Animals; Colchicine; Depression, Chemical; Dirofilaria; Dose-Response Relationship, Drug; Female; Filarioidea; Mebendazole; Metaphase; Methods; Microtubules; Mitosis; Oogonia; Tubulin

1985
Intestinal tubulin as possible target for the chemotherapeutic action of mebendazole in parasitic nematodes.
    Molecular and biochemical parasitology, 1981, Dec-31, Volume: 4, Issue:5-6

    Topics: Animals; Ascaris; Benzimidazoles; Binding, Competitive; Colchicine; Kinetics; Mebendazole; Tubulin

1981
Inhibition of [3H]mebendazole binding to tubulin by structurally diverse microtubule inhibitors which interact at the colchicine binding site.
    Biochemistry and molecular biology international, 1995, Volume: 35, Issue:6

    Topics: Animals; Binding Sites; Colchicine; Mebendazole; Microtubules; Protein Binding; Radioligand Assay; Sheep; Tritium; Tubulin

1995
Indications for a threshold of chemically-induced aneuploidy in vitro in human lymphocytes.
    Environmental and molecular mutagenesis, 1995, Volume: 26, Issue:4

    Topics: Adult; Aneuploidy; Benzimidazoles; Carbamates; Cell Division; Cell Survival; Cells, Cultured; Centromere; Colchicine; Flow Cytometry; Humans; In Situ Hybridization, Fluorescence; Lymphocytes; Mebendazole; Methyl Methanesulfonate; Micronucleus Tests; Mitomycin; Mutagens; Nocodazole

1995
Indication for thresholds of chromosome non-disjunction versus chromosome lagging induced by spindle inhibitors in vitro in human lymphocytes.
    Mutagenesis, 1997, Volume: 12, Issue:3

    Topics: Adult; Aneuploidy; Benzimidazoles; Carbamates; Chromosomes, Human; Chromosomes, Human, Pair 1; Chromosomes, Human, Pair 17; Colchicine; Dose-Response Relationship, Drug; Female; Humans; In Vitro Techniques; Lymphocytes; Male; Mebendazole; Methyl Methanesulfonate; Micronucleus Tests; Mutagens; Mutation; Nocodazole; Spindle Apparatus

1997
Spindle poisons can induce polyploidy by mitotic slippage and micronucleate mononucleates in the cytokinesis-block assay.
    Mutagenesis, 1998, Volume: 13, Issue:2

    Topics: Benzimidazoles; Carbamates; Colchicine; Female; Humans; Leukocyte Count; Leukocytes, Mononuclear; Male; Mebendazole; Methyl Methanesulfonate; Micronuclei, Chromosome-Defective; Micronucleus Tests; Mitomycin; Mutagens; Nocodazole; Polyploidy; Spindle Apparatus

1998
Rapid colchicine competition-binding scintillation proximity assay using biotin-labeled tubulin.
    BioTechniques, 2000, Volume: 29, Issue:1

    Topics: Aminophenols; Bibenzyls; Binding Sites; Binding, Competitive; Biotinylation; Colchicine; Demecolcine; Mebendazole; Microspheres; Podophyllotoxin; Scintillation Counting; Solvents; Stilbenes; Streptavidin; Sulfonamides; Tritium; Tubulin; Yttrium

2000
Adherence of Giardia lamblia trophozoites to Int-407 human intestinal cells.
    Clinical and diagnostic laboratory immunology, 2001, Volume: 8, Issue:2

    Topics: Animals; Antinematodal Agents; Cell Adhesion; Chelating Agents; Colchicine; Cytochalasin B; Cytochalasin D; Cytoskeleton; Edetic Acid; Epithelial Cells; Fixatives; Giardia lamblia; Glutaral; Humans; Ileum; In Vitro Techniques; Jejunum; Lectins; Mannosephosphates; Mebendazole; Microscopy, Electron; Microscopy, Electron, Scanning; Nucleic Acid Synthesis Inhibitors

2001