Page last updated: 2024-09-04

mdl 74156 and diphenhydramine

mdl 74156 has been researched along with diphenhydramine in 2 studies

Compound Research Comparison

Studies
(mdl 74156)
Trials
(mdl 74156)
Recent Studies (post-2010)
(mdl 74156)
Studies
(diphenhydramine)
Trials
(diphenhydramine)
Recent Studies (post-2010) (diphenhydramine)
14524,146415542

Protein Interaction Comparison

ProteinTaxonomymdl 74156 (IC50)diphenhydramine (IC50)
5-hydroxytryptamine receptor 4Cavia porcellus (domestic guinea pig)0.98
Aldo-keto reductase family 1 member B1Rattus norvegicus (Norway rat)3.542
Muscarinic acetylcholine receptor M2Homo sapiens (human)1.05
Muscarinic acetylcholine receptor M4Homo sapiens (human)0.372
Muscarinic acetylcholine receptor M5Homo sapiens (human)0.162
Muscarinic acetylcholine receptor M1Homo sapiens (human)0.346
Muscarinic acetylcholine receptor M3Homo sapiens (human)0.647
Sodium-dependent noradrenaline transporter Homo sapiens (human)3.542
5-hydroxytryptamine receptor 2AHomo sapiens (human)1.295
5-hydroxytryptamine receptor 2CHomo sapiens (human)0.98
Histamine H1 receptorHomo sapiens (human)0.171
5-hydroxytryptamine receptor 2BHomo sapiens (human)1.118
Potassium voltage-gated channel subfamily H member 2Homo sapiens (human)3.8852

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (50.00)29.6817
2010's1 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Jia, L; Sun, H1
Sen, S; Sinha, N1

Other Studies

2 other study(ies) available for mdl 74156 and diphenhydramine

ArticleYear
Support vector machines classification of hERG liabilities based on atom types.
    Bioorganic & medicinal chemistry, 2008, Jun-01, Volume: 16, Issue:11

    Topics: Animals; Arrhythmias, Cardiac; CHO Cells; Computer Simulation; Cricetinae; Cricetulus; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Models, Chemical; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels, Voltage-Gated; Predictive Value of Tests; ROC Curve

2008
Predicting hERG activities of compounds from their 3D structures: development and evaluation of a global descriptors based QSAR model.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:2

    Topics: Computer Simulation; Ether-A-Go-Go Potassium Channels; Humans; Molecular Structure; Organic Chemicals; Quantitative Structure-Activity Relationship

2011