mdl 74156 has been researched along with desipramine in 2 studies
| Studies (mdl 74156) | Trials (mdl 74156) | Recent Studies (post-2010) (mdl 74156) | Studies (desipramine) | Trials (desipramine) | Recent Studies (post-2010) (desipramine) |
|---|---|---|---|---|---|
| 14 | 5 | 2 | 5,775 | 487 | 414 |
| Protein | Taxonomy | mdl 74156 (IC50) | desipramine (IC50) |
|---|---|---|---|
| Solute carrier family 22 member 1 | Homo sapiens (human) | 9.18 | |
| 5-hydroxytryptamine receptor 2C | Rattus norvegicus (Norway rat) | 0.35 | |
| Alpha-2A adrenergic receptor | Homo sapiens (human) | 0.0003 | |
| 5-hydroxytryptamine receptor 2A | Rattus norvegicus (Norway rat) | 0.35 | |
| Alpha-1B adrenergic receptor | Rattus norvegicus (Norway rat) | 0.0034 | |
| Alpha-2B adrenergic receptor | Homo sapiens (human) | 0.0003 | |
| Alpha-2C adrenergic receptor | Homo sapiens (human) | 0.0003 | |
| 5-hydroxytryptamine receptor 1A | Rattus norvegicus (Norway rat) | 0.35 | |
| Sodium-dependent noradrenaline transporter | Homo sapiens (human) | 0.0031 | |
| Sodium-dependent dopamine transporter | Rattus norvegicus (Norway rat) | 7.8 | |
| 5-hydroxytryptamine receptor 1B | Rattus norvegicus (Norway rat) | 0.35 | |
| 5-hydroxytryptamine receptor 1D | Rattus norvegicus (Norway rat) | 0.35 | |
| 5-hydroxytryptamine receptor 1F | Rattus norvegicus (Norway rat) | 0.35 | |
| 5-hydroxytryptamine receptor 2B | Rattus norvegicus (Norway rat) | 0.35 | |
| 5-hydroxytryptamine receptor 6 | Rattus norvegicus (Norway rat) | 0.35 | |
| Histamine H1 receptor | Rattus norvegicus (Norway rat) | 0.0008 | |
| Sodium-dependent serotonin transporter | Homo sapiens (human) | 0.1961 | |
| 5-hydroxytryptamine receptor 7 | Rattus norvegicus (Norway rat) | 0.35 | |
| 5-hydroxytryptamine receptor 5A | Rattus norvegicus (Norway rat) | 0.35 | |
| 5-hydroxytryptamine receptor 5B | Rattus norvegicus (Norway rat) | 0.35 | |
| 5-hydroxytryptamine receptor 3A | Rattus norvegicus (Norway rat) | 0.35 | |
| Alpha-1A adrenergic receptor | Rattus norvegicus (Norway rat) | 0.0003 | |
| Histamine H2 receptor | Cavia porcellus (domestic guinea pig) | 3.8 | |
| Sodium-dependent dopamine transporter | Homo sapiens (human) | 9.9 | |
| Potassium voltage-gated channel subfamily H member 2 | Homo sapiens (human) | 1.4035 | |
| Sodium channel protein type 5 subunit alpha | Homo sapiens (human) | 1.52 | |
| 5-hydroxytryptamine receptor 4 | Rattus norvegicus (Norway rat) | 0.35 | |
| 5-hydroxytryptamine receptor 3B | Rattus norvegicus (Norway rat) | 0.35 | |
| Solute carrier family 22 member 2 | Rattus norvegicus (Norway rat) | 10 | |
| Transporter | Rattus norvegicus (Norway rat) | 7.8 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Jia, L; Sun, H | 1 |
| Sen, S; Sinha, N | 1 |
2 other study(ies) available for mdl 74156 and desipramine
| Article | Year |
|---|---|
Support vector machines classification of hERG liabilities based on atom types.
Topics: Animals; Arrhythmias, Cardiac; CHO Cells; Computer Simulation; Cricetinae; Cricetulus; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Models, Chemical; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels, Voltage-Gated; Predictive Value of Tests; ROC Curve | 2008 |
Predicting hERG activities of compounds from their 3D structures: development and evaluation of a global descriptors based QSAR model.
Topics: Computer Simulation; Ether-A-Go-Go Potassium Channels; Humans; Molecular Structure; Organic Chemicals; Quantitative Structure-Activity Relationship | 2011 |