mdl 74156 has been researched along with aprepitant in 1 studies
| Studies (mdl 74156) | Trials (mdl 74156) | Recent Studies (post-2010) (mdl 74156) | Studies (aprepitant) | Trials (aprepitant) | Recent Studies (post-2010) (aprepitant) |
|---|---|---|---|---|---|
| 14 | 5 | 2 | 769 | 229 | 521 |
| Protein | Taxonomy | mdl 74156 (IC50) | aprepitant (IC50) |
|---|---|---|---|
| Cytochrome P450 3A4 | Homo sapiens (human) | 0.046 | |
| Substance-P receptor | Homo sapiens (human) | 0.0002 | |
| Substance-P receptor | Meriones unguiculatus (Mongolian gerbil) | 0.0001 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ahmed, T; Li, SX; Lupinacci, P; Majumdar, A; Murphy, MG; Panebianco, D; Pequignot, E; Petty, KJ; Rosen, L; Royalty, JE; Rushmore, TH | 1 |
1 trial(s) available for mdl 74156 and aprepitant
| Article | Year |
|---|---|
Lack of effect of aprepitant on hydrodolasetron pharmacokinetics in CYP2D6 extensive and poor metabolizers.
Topics: Administration, Oral; Adult; Antiemetics; Aprepitant; Cross-Over Studies; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Electrocardiography; Enzyme Inhibitors; Female; Genotype; Humans; Indoles; Male; Middle Aged; Morpholines; Quinolizines; Reference Values; Serotonin Antagonists | 2006 |