mdl 73404 has been researched along with d-alpha tocopherol in 18 studies
| Studies (mdl 73404) | Trials (mdl 73404) | Recent Studies (post-2010) (mdl 73404) | Studies (d-alpha tocopherol) | Trials (d-alpha tocopherol) | Recent Studies (post-2010) (d-alpha tocopherol) |
|---|---|---|---|---|---|
| 20 | 0 | 0 | 32,198 | 2,903 | 7,258 |
| Protein | Taxonomy | mdl 73404 (IC50) | d-alpha tocopherol (IC50) |
|---|---|---|---|
| Glutathione S-transferase P | Homo sapiens (human) | 0.5 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 17 (94.44) | 18.2507 |
| 2000's | 1 (5.56) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bolkenius, FN; Grisar, JM; Petty, MA; Verne, J | 1 |
| De Jong, W; Grisar, JM; Petty, MA | 1 |
| Bolkenius, FN | 1 |
| Bolkenius, FN; De Jong, W; Grisar, JM | 1 |
| Bolkenius, FN; De Jong, W; Dow, J; Grisar, JM; Haegele, KD; Petty, MA; Wagner, ER; Wagner, J | 1 |
| Bolli, R; Halliwell, B; Kaur, H; Park, SW; Qiu, Y; Schleman, M; Sun, JZ; Tang, XL | 1 |
| Carrel, BK; Ho, J; Kuo, BS; Mathews, BS; Rose, JQ; Stuhler, JD | 1 |
| Bolli, R; Hartley, CJ; McCay, PB; Schleman, M; Sun, JZ; Tang, XL | 1 |
| Gvozdják, J; Gvozdjáková, A; Herichová, I; Kucharská, J | 1 |
| Chan, KY; Chen, TM; Dusterhoft, DA | 1 |
| Bolkenius, FN; De Jong, W; Dow, J; Grisar, JM; Lukovic, L; Petty, MA | 2 |
| Barclay, LR; Vinqvist, MR | 1 |
| Bolli, R; Jeroudi, MO; Schleman, M; Tang, XL; Zughaib, ME | 1 |
| Bada, V; Gvozdjáková, A; Herichová, I; Kucharská, J; Snircová, M | 1 |
| de Jong, W; Jones, CR; Lukovic, L; Petty, MA | 1 |
| Depace, DE; Fondacaro, JD; Hui-Qi, Q; Murthy, S; Sakai, T | 1 |
| García-Carmona, F; Núñez-Delicado, E; Sánchez-Ferrer, A; Sojo, M | 1 |
18 other study(ies) available for mdl 73404 and d-alpha tocopherol
| Article | Year |
|---|---|
2,3-Dihydro-1-benzofuran-5-ols as analogues of alpha-tocopherol that inhibit in vitro and ex vivo lipid autoxidation and protect mice against central nervous system trauma.
Topics: Animals; Benzofurans; Brain; Cerebrovascular Disorders; Craniocerebral Trauma; Drug Evaluation, Preclinical; Free Radical Scavengers; Lipid Peroxidation; Male; Mice; Superoxides; Vitamin E | 1995 |
Protective effects of an alpha-tocopherol analogue against myocardial reperfusion injury in rats.
Topics: Animals; Cardioplegic Solutions; Cardiovascular Agents; Coronary Disease; Free Radical Scavengers; In Vitro Techniques; Male; Myocardial Infarction; Myocardial Reperfusion Injury; Rats; Rats, Inbred Strains; Vitamin E | 1992 |
Leukocyte-mediated inactivation of alpha 1-proteinase inhibitor is inhibited by amino analogues of alpha-tocopherol.
Topics: alpha 1-Antitrypsin; Exocytosis; Glucose Oxidase; Humans; Hydrogen Peroxide; Leukocytes; NADH, NADPH Oxidoreductases; NADPH Oxidases; Pancreatic Elastase; Peroxidase; Superoxides; Tocopherols; Vitamin E; Xanthine Oxidase | 1991 |
A water-soluble quaternary ammonium analog of alpha-tocopherol, that scavenges lipoperoxyl, superoxyl and hydroxyl radicals.
Topics: Animals; Antioxidants; Brain; Chromans; Deoxyribose; Depression, Chemical; Free Radical Scavengers; Free Radicals; Kinetics; Lipid Metabolism; Lipid Peroxidation; Male; Malondialdehyde; Microsomes; Myocardium; Oxidation-Reduction; Oxygen; Rats; Rats, Inbred Strains; Solubility; Tocopherols; Vitamin E | 1991 |
A cardioselective, hydrophilic N,N,N-trimethylethanaminium alpha-tocopherol analogue that reduces myocardial infarct size.
Topics: Animals; Benzopyrans; Brain; Cardiovascular Agents; Free Radical Scavengers; Indicators and Reagents; Lipid Peroxidation; Molecular Structure; Myocardial Infarction; Myocardial Reperfusion Injury; Rats; Structure-Activity Relationship; Tissue Distribution; Vitamin E | 1991 |
Effect of the hydrophilic alpha-tocopherol analog MDL 74,405 on detection of hydroxyl radicals in stunned myocardium in dogs.
Topics: Animals; Antioxidants; Coronary Circulation; Dogs; Female; Free Radical Scavengers; Heart; Hemodynamics; Hydroxylation; Male; Myocardial Stunning; Myocardium; Phenylalanine; Tyrosine; Vitamin E | 1995 |
Disposition and cardioselectivity of MDL 74,405, a vitamin E-like free radical scavenger, in rats and dogs after intravenous infusion.
Topics: Animals; Carbon Radioisotopes; Cardiovascular Agents; Dogs; Free Radical Scavengers; Infusions, Intravenous; Male; Myocardial Reperfusion Injury; Myocardium; Rats; Rats, Sprague-Dawley; Tissue Distribution; Vitamin E | 1995 |
Inhibitory effect of a hydrophilic alpha-tocopherol analogue, MDL 74,405, on generation of free radicals in stunned myocardium in dogs.
Topics: Animals; Blood Pressure; Body Temperature; Coronary Circulation; Cyclic N-Oxides; Dogs; Electron Spin Resonance Spectroscopy; Free Radicals; Heart Rate; Myocardial Reperfusion; Myocardial Stunning; Myocardium; Nitrogen Oxides; Oxidative Stress; Time Factors; Vitamin E | 1995 |
[Significance of mitochondrial Ca2+ transport in ischemic injury and myocardial protection].
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antioxidants; Biological Transport; Calcium; Enalapril; In Vitro Techniques; Magnesium; Male; Mitochondria, Heart; Myocardial Reperfusion Injury; Rabbits; Vitamin E | 1994 |
Determination of MDL 74,405, a synthetic analogue of alpha-tocopherol, in dog plasma and heart tissue by high-performance liquid chromatography with electrochemical detection.
Topics: Animals; Chromatography, High Pressure Liquid; Dogs; Electrochemistry; Free Radical Scavengers; Myocardium; Stereoisomerism; Vitamin E | 1994 |
Myocardial protection by a cardioselective free radical scavenger.
Topics: Animals; Cardiovascular Agents; Creatine Kinase; Free Radical Scavengers; Heart; In Vitro Techniques; Lipid Peroxidation; Male; Mice; Molecular Conformation; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium; Rats; Rats, Sprague-Dawley; Vitamin E | 1994 |
Membrane peroxidation: inhibiting effects of water-soluble antioxidants on phospholipids of different charge types.
Topics: Antioxidants; Chromans; Free Radical Scavengers; Kinetics; Lipid Peroxidation; Liposomes; Membrane Lipids; Models, Biological; Oxygen Consumption; Phospholipids; Structure-Activity Relationship; Vitamin E | 1994 |
Beneficial effects of MDL 74,405, a cardioselective water soluble alpha tocopherol analogue, on the recovery of function of stunned myocardium in intact dogs.
Topics: Animals; Cardiovascular Agents; Dogs; Free Radical Scavengers; Heart; Hemodynamics; Myocardial Stunning; Myocardium; Regional Blood Flow; Vitamin E | 1994 |
Protection of infarcted, chronically reperfused hearts by an alpha-tocopherol analogue.
Topics: Animals; Cardiovascular Agents; Catecholamines; Coronary Circulation; Creatine Kinase; Epinephrine; Free Radical Scavengers; In Vitro Techniques; Lipid Peroxidation; Lipid Peroxides; Male; Myocardial Contraction; Myocardial Infarction; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium; Norepinephrine; Rats; Rats, Sprague-Dawley; Vitamin E | 1993 |
[The effect of an alpha-tocopherol analog, MDL 73404, on myocardial bioenergetics].
Topics: Adenine Nucleotides; Adult; Aged; Aged, 80 and over; Animals; Cardiovascular Agents; Energy Metabolism; Female; Free Radical Scavengers; Humans; Hypoxanthine; Hypoxanthines; Inosine; Male; Middle Aged; Myocardium; Phosphates; Rats; Rats, Wistar; Vitamin E; Xanthine; Xanthines | 1996 |
Receptor density in the rat heart following ischaemia and prolonged reperfusion.
Topics: Animals; Autoradiography; Free Radical Scavengers; Heart Ventricles; Myocardial Contraction; Myocardial Infarction; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium; Rats; Receptors, Adrenergic, beta-1; Receptors, Adrenergic, beta-2; Vitamin E | 1995 |
Ischemia/reperfusion injury in the rat colon.
Topics: 6-Ketoprostaglandin F1 alpha; Aerobiosis; Aminosalicylic Acids; Anaerobiosis; Animals; Antioxidants; Arachidonic Acid; Colon; Disease Models, Animal; Glutathione; Lactic Acid; Male; Mesalamine; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Thiobarbituric Acid Reactive Substances; Thromboxane B2; Vitamin E; Xanthine Oxidase | 1997 |
Anomalous oxidation of MDL 73,404 by horseradish peroxidase.
Topics: Coumaric Acids; Horseradish Peroxidase; Hydrogen Peroxide; Kinetics; Linear Models; Oxidation-Reduction; Propionates; Quinones; Spectrophotometry; Vitamin E | 2003 |