Compounds > mdl 72527

mdl 72527 and spermidine

mdl 72527 has been researched along with spermidine in 19 studies

Research

Studies (19)

Timeframe	Studies, this research(%)	All Research%
pre-1990	4 (21.05)	18.7374
1990's	7 (36.84)	18.2507
2000's	5 (26.32)	29.6817
2010's	3 (15.79)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Elzinga, H; Hessels, J; Kingma, AW; Muskiet, FA; Sturkenboom, MC; van den Berg, GA	1
Knödgen, B; Moulinoux, JP; Quemener, V; Sarhan, S; Seiler, N	1
Kadofuku, T; Sato, T; Shinki, T; Suda, T; Tanaka, H	1
Bowlin, TL; Flescher, E; Talal, N	1
Bolkenius, FN; Seiler, N	1
Bey, P; Bolkenius, FN; Seiler, N	1
Doyle, KM; Shaw, GG	1
Baudry, M; Najm, I	1
Hu, RH; Pegg, AE	1
Boggs, SS; Deutsch, M; Grudziak, AG; Redgate, ES	1
Cleveland, JL; Dai, H; Kramer, DL; Murti, KG; Porter, CW; Yang, C	1
Dempsey, RJ; Doğan, A; Hatcher, JF; Rao, AM	1
Fujiwara, K; Nagoshi, S; Ota, S	1
Seiler, N	1
Aoudé-Werner, D; Geoffroy, P; Gossé, F; Marchioni, E; Miesch, M; Raul, F; Roussi, S; Zhang, X	1
Foltzer-Jourdainne, C; Gossé, F; Habold, C; Lobstein, A; Maldonado-Celisa, ME; Raul, F; Roessner, A; Roussia, S; Schneider-Stock, R	1
Alhonen, L; Cerrada-Gimenez, M; Jänne, J; Keinänen, TA; Khomutov, AR; Pietilä, M; Pirinen, E; Uimari, A; Vuohelainen, S	1
Agostinelli, E; Bonaiuto, E; Colone, M; Di Paolo, ML; Grancara, S; Macone, A; Martinis, P; Stevanato, R; Stringaro, A; Toninello, A; Vianello, F	1
Aagaard, A; Barlind, L; Fjellström, O; Kaminski, TP; Kashima, A; Kumanomidou, T; Sjögren, T; Snijder, A; Wassvik, CM; Yokota, T	1

Reviews

1 review(s) available for mdl 72527 and spermidine

Article	Year
How important is the oxidative degradation of spermine?: minireview article. Amino acids, 2004, Volume: 26, Issue:4 Topics: Animals; Erythrocytes; Oxidation-Reduction; Oxidoreductases Acting on CH-NH Group Donors; Polyamine Oxidase; Putrescine; Spermidine; Spermine	2004

Other Studies

18 other study(ies) available for mdl 72527 and spermidine

Article	Year
Gas chromatographic determination of N-acetylisoputreanine-gamma-lactam, a unique catabolite of N1-acetylspermidine. Journal of chromatography, 1991, Jan-18, Volume: 563, Issue:1 Topics: Animals; Chromatography, Gas; Female; Guanidines; Humans; Oxidoreductases Acting on CH-NH Group Donors; Polyamine Oxidase; Putrescine; Pyrrolidinones; Rats; Rats, Inbred Strains; Reference Values; Spermidine; Swine	1991
On the degradation and elimination of spermine by the vertebrate organism. The International journal of biochemistry, 1991, Volume: 23, Issue:5-6 Topics: Animals; Erythrocytes; Female; Kinetics; Male; Mice; Mice, Inbred C57BL; Polyamines; Putrescine; Rats; Rats, Inbred Strains; Spermidine	1991
Major pathway for putrescine synthesis induced by 1 alpha,25-dihydroxyvitamin D3 in chick duodenum. Gastroenterology, 1989, Volume: 96, Issue:6 Topics: Acetyltransferases; Animals; Calcitriol; Chickens; Duodenum; In Vitro Techniques; Male; Ornithine; Ornithine Decarboxylase; Oxidoreductases Acting on CH-NH Group Donors; Polyamine Oxidase; Putrescine; Spermidine	1989
Polyamine oxidation down-regulates IL-2 production by human peripheral blood mononuclear cells. Journal of immunology (Baltimore, Md. : 1950), 1989, Feb-01, Volume: 142, Issue:3 Topics: Adult; Cell Membrane; Female; Humans; Hydrogen Peroxide; Interleukin-2; Leukocytes, Mononuclear; Male; Middle Aged; Ornithine Decarboxylase Inhibitors; Oxidoreductases Acting on CH-NH Group Donors; Polyamine Oxidase; Putrescine; Spermidine; T-Lymphocytes	1989
The role of polyamine reutilization in depletion of cellular stores of polyamines in non-proliferating tissues. Biochimica et biophysica acta, 1987, Jan-20, Volume: 923, Issue:1 Topics: Amino Acids; Animals; Brain; Eflornithine; Kidney; Liver; Male; Mice; Ornithine Decarboxylase Inhibitors; Oxidoreductases Acting on CH-NH Group Donors; Polyamine Oxidase; Polyamines; Putrescine; Spermidine	1987
Specific inhibition of polyamine oxidase in vivo is a method for the elucidation of its physiological role. Biochimica et biophysica acta, 1985, Jan-28, Volume: 838, Issue:1 Topics: Animals; Brain; Carbon Tetrachloride; Dose-Response Relationship, Drug; Kidney; Kinetics; Liver; Male; Mice; Oxidoreductases Acting on CH-NH Group Donors; Polyamine Oxidase; Putrescine; Spermidine; Spermine	1985
The mechanism of the neurotoxic effects of spermidine. Biochemical Society transactions, 1994, Volume: 22, Issue:4 Topics: Animals; Cerebral Ventricles; Dizocilpine Maleate; Guanidines; Injections, Intraventricular; Male; Mice; Mice, Inbred Strains; Motor Activity; Neurotoxins; Oxidoreductases Acting on CH-NH Group Donors; Piperidines; Putrescine; Receptors, N-Methyl-D-Aspartate; Spermidine; Stereotyped Behavior	1994
Kainate-induced seizure activity stimulates the polyamine interconversion pathway in rat brain. Neuroscience letters, 1994, Apr-25, Volume: 171, Issue:1-2 Topics: Acetylation; Acetyltransferases; Animals; Biogenic Polyamines; Brain; Brain Chemistry; Kainic Acid; Male; Ornithine Decarboxylase; Oxidoreductases Acting on CH-NH Group Donors; Polyamine Oxidase; Putrescine; Rats; Rats, Sprague-Dawley; Seizures; Spermidine; Spermine	1994
Rapid induction of apoptosis by deregulated uptake of polyamine analogues. The Biochemical journal, 1997, Nov-15, Volume: 328 ( Pt 1) Topics: Alkylation; Animals; Apoptosis; Cell Death; CHO Cells; Cricetinae; Cycloheximide; Cysteine Proteinase Inhibitors; Eflornithine; Oxidoreductases Acting on CH-NH Group Donors; Polyamines; Putrescine; Spermidine; Spermine	1997
Enhanced uptake of [3H] spermidine by 9L rat brain tumors after direct intratumoral infusion of inhibitors of enzymes of the polyamine biosynthetic pathway. Journal of neuro-oncology, 1999, Volume: 42, Issue:2 Topics: Adenosylmethionine Decarboxylase; Animals; Biological Transport; Body Weight; Brain Neoplasms; Corpus Striatum; Deoxyadenosines; Eflornithine; Enzyme Inhibitors; Gliosarcoma; Infusions, Parenteral; Male; Oxidoreductases Acting on CH-NH Group Donors; Putrescine; Rats; Rats, Inbred F344; Spermidine; Tritium; Tumor Cells, Cultured	1999
The polyamine oxidase inhibitor MDL-72,527 selectively induces apoptosis of transformed hematopoietic cells through lysosomotropic effects. Cancer research, 1999, Oct-01, Volume: 59, Issue:19 Topics: Animals; Apoptosis; bcl-X Protein; Cell Cycle; Cell Death; Cell Line, Transformed; Cell Survival; Cell Transformation, Neoplastic; Eflornithine; Hematopoietic Stem Cells; Humans; Interleukin-3; Kinetics; Lysosomes; Mice; Oxidoreductases Acting on CH-NH Group Donors; Polyamine Oxidase; Polyamines; Proto-Oncogene Proteins c-bcl-2; Putrescine; Spermidine; Spermine	1999
Elevated N1-acetylspermidine levels in gerbil and rat brains after CNS injury. Journal of neurochemistry, 2000, Volume: 74, Issue:3 Topics: Animals; Arterial Occlusive Diseases; Blood-Brain Barrier; Brain; Brain Injuries; Cerebral Arteries; Gerbillinae; Ischemic Attack, Transient; Male; Prosencephalon; Putrescine; Rats; Rats, Inbred SHR; Rats, Sprague-Dawley; Reperfusion Injury; Spermidine	2000
Contribution of spermidine to stimulation by hepatocyte growth factor in repair after damage of rabbit gastric mucosal cells in primary culture. Biochimica et biophysica acta, 2003, Jan-20, Volume: 1619, Issue:2 Topics: Animals; Cells, Cultured; DNA Repair; Eflornithine; Enzyme Inhibitors; Epithelial Cells; Gastric Mucosa; Hepatocyte Growth Factor; Putrescine; Rabbits; Spermidine; Wound Healing	2003
Perturbation of polyamine metabolism and its relation to cell death in human colon cancer cells treated by 7beta-hydroxycholesterol and 7beta-hydroxysitosterol. International journal of oncology, 2006, Volume: 29, Issue:6 Topics: Biogenic Polyamines; Caco-2 Cells; Cell Death; Cell Growth Processes; Colonic Neoplasms; Drug Synergism; Flow Cytometry; Humans; Hydroxycholesterols; Putrescine; Sitosterols; Spermidine	2006
Modulation by polyamines of apoptotic pathways triggered by procyanidins in human metastatic SW620 cells. Cellular and molecular life sciences : CMLS, 2008, Volume: 65, Issue:9 Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cell Line, Tumor; Colonic Neoplasms; Enzyme Inhibitors; Histone Deacetylases; Humans; Membrane Potential, Mitochondrial; Neoplasm Metastasis; Oxidoreductases Acting on CH-NH Group Donors; Polyamine Oxidase; Polyamines; Proanthocyanidins; Putrescine; Receptors, TNF-Related Apoptosis-Inducing Ligand; Spermidine	2008
Spermidine is indispensable in differentiation of 3T3-L1 fibroblasts to adipocytes. Journal of cellular and molecular medicine, 2010, Volume: 14, Issue:6B Topics: 3T3-L1 Cells; Adipocytes; Adipogenesis; Animals; Cell Differentiation; Cell Proliferation; Cell Shape; Eflornithine; Fibroblasts; Gene Expression Regulation; Glucose Transporter Type 4; Isomerism; Lipid Metabolism; Mice; Organ Specificity; Putrescine; Spermidine; Time Factors	2010
A novel enzyme with spermine oxidase properties in bovine liver mitochondria: identification and kinetic characterization. Free radical biology & medicine, 2015, Volume: 81 Topics: Animals; Catalytic Domain; Cattle; Hydrogen Peroxide; Kinetics; Liver; Mitochondria, Liver; Osmolar Concentration; Oxidation-Reduction; Oxidoreductases Acting on CH-NH Group Donors; Polyamine Oxidase; Putrescine; Spermidine; Spermine; Static Electricity; Substrate Specificity	2015
The Structure of Murine N Biochemistry, 2017, 01-24, Volume: 56, Issue:3 Topics: Aldehydes; Animals; Catalytic Domain; Gene Expression; Hydrogen Peroxide; Kinetics; Mice; Models, Molecular; Oxidation-Reduction; Oxidoreductases; Propylamines; Protein Structure, Secondary; Putrescine; Spermidine; Spermine	2017