mdl 72527 has been researched along with eflornithine in 17 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (11.76) | 18.7374 |
| 1990's | 11 (64.71) | 18.2507 |
| 2000's | 3 (17.65) | 29.6817 |
| 2010's | 1 (5.88) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cipolla, B; Guillé, F; Havouis, R; Lobel, B; Martin, C; Moulinoux, JP; Quemener, V; Seiler, N | 1 |
| Nakamura, Y; Shinki, T; Suda, T; Takito, J; Tanaka, H; Yamaguchi, A; Yoshiki, S | 1 |
| Hessels, J; Kingma, AW; Muskiet, FA; Sarhan, S; Seiler, N | 1 |
| Grauffel, C; Jones, R; Knödgen, B; Moulinoux, JP; Sarhan, S; Seiler, N | 1 |
| Bolkenius, FN; Seiler, N | 1 |
| Gerhart, F; Knödgen, B; Sarhan, S; Seiler, N | 1 |
| Fölsch, UR; Löser, C | 1 |
| Blanchard, Y; Chamaillard, L; Cipolla, B; Guillé, F; Havouis, R; Moulinoux, JP; Quemener, V | 1 |
| Bansard, JY; Catros-Quemener, V; Chamaillard, L; Commeurec, A; Delcros, JG; Desury, D; Genetet, N; Havouis, R; Moulinoux, JP | 1 |
| Hu, RH; Pegg, AE | 1 |
| Arakawa, T; Hasuma, T; Kobayashi, K; Matsui-Yuasa, I; Otani, K; Otani, S; Yano, Y | 1 |
| Boggs, SS; Deutsch, M; Grudziak, AG; Redgate, ES | 1 |
| Cleveland, JL; Dai, H; Kramer, DL; Murti, KG; Porter, CW; Yang, C | 1 |
| Badolo, L; Duranton, B; Gossé, F; Raul, F; Schneider, Y; Seiler, N; Vincent, F | 1 |
| Fujiwara, K; Nagoshi, S; Ota, S | 1 |
| Diegelman, P; Kee, K; Kisiel, N; Kramer, DL; Merali, S; Porter, CW; Powell, CT; Vujcic, S | 1 |
| Alhonen, L; Cerrada-Gimenez, M; Jänne, J; Keinänen, TA; Khomutov, AR; Pietilä, M; Pirinen, E; Uimari, A; Vuohelainen, S | 1 |
17 other study(ies) available for mdl 72527 and eflornithine
| Article | Year |
|---|---|
The growth of MAT-LyLu rat prostatic adenocarcinoma can be prevented in vivo by polyamine deprivation.
Topics: Adenocarcinoma; Animals; Diet; Doxorubicin; Drug Screening Assays, Antitumor; Drug Synergism; Eflornithine; Male; Neomycin; Neoplasm Transplantation; Oxidoreductases Acting on CH-NH Group Donors; Polyamine Oxidase; Polyamines; Prostatic Neoplasms; Putrescine; Rats; Rats, Inbred Strains | 1991 |
Putrescine is involved in the vitamin D action in chick intestine.
Topics: Acetyltransferases; Alkaline Phosphatase; Animals; Calcium; Chick Embryo; Chickens; Duodenum; Eflornithine; Ornithine Decarboxylase; Oxidoreductases Acting on CH-NH Group Donors; Polyamine Oxidase; Putrescine; Vitamin D | 1991 |
Growth inhibition of two solid tumors in mice, caused by polyamine depletion, is not attended by alterations in cell-cycle phase distribution.
Topics: Animals; Cell Cycle; Cell Division; Eflornithine; Female; Fibrosarcoma; Kinetics; Lung Neoplasms; Mice; Mice, Inbred C57BL; Polyamines; Putrescine; Sarcoma, Experimental | 1991 |
Endogenous and exogenous polyamines in support of tumor growth.
Topics: Animals; Antineoplastic Agents; Cell Division; Eflornithine; Female; Leukocyte Count; Lung Neoplasms; Mice; Mice, Inbred C57BL; Neoplasm Metastasis; Ornithine Decarboxylase Inhibitors; Polyamines; Putrescine | 1990 |
The role of polyamine reutilization in depletion of cellular stores of polyamines in non-proliferating tissues.
Topics: Amino Acids; Animals; Brain; Eflornithine; Kidney; Liver; Male; Mice; Ornithine Decarboxylase Inhibitors; Oxidoreductases Acting on CH-NH Group Donors; Polyamine Oxidase; Polyamines; Putrescine; Spermidine | 1987 |
Chain-fluorinated polyamines as tumor markers. II. Metabolic aspects in normal tissues.
Topics: Animals; Biomarkers, Tumor; Eflornithine; Fluorine; Half-Life; Mice; Ornithine Decarboxylase; Oxidoreductases Acting on CH-NH Group Donors; Polyamine Oxidase; Polyamines; Putrescine | 1988 |
Importance of various intracellular regulatory mechanisms of polyamine metabolism in camostate-induced pancreatic growth in rats.
Topics: Amine Oxidase (Copper-Containing); Animals; Biogenic Polyamines; Eflornithine; Esters; Gabexate; Guanidines; Male; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Oxidoreductases Acting on CH-NH Group Donors; Pancreas; Putrescine; Rats; Rats, Wistar; Time Factors; Trypsin Inhibitors | 1993 |
In vivo, synergestic inhibition of MAT-LyLu rat prostatic adenocarcinoma growth by polyamine deprivation and low-dose cyclophosphamide.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Eflornithine; Lung Neoplasms; Male; Metronidazole; Neomycin; Oxidoreductases Acting on CH-NH Group Donors; Polyamines; Prostatic Neoplasms; Protein Synthesis Inhibitors; Putrescine; Rats; Rats, Inbred Strains; Survival Rate | 1996 |
Polyamine deprivation prevents the development of tumour-induced immune suppression.
Topics: Animals; Carcinoma, Lewis Lung; Dinoprostone; Eflornithine; Enzyme Inhibitors; Immune Tolerance; Interleukin-2; Lymphocyte Activation; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Neoplasm Transplantation; Organ Size; Oxidoreductases Acting on CH-NH Group Donors; Polyamine Oxidase; Polyamines; Putrescine; Spleen; T-Lymphocytes | 1997 |
Rapid induction of apoptosis by deregulated uptake of polyamine analogues.
Topics: Alkylation; Animals; Apoptosis; Cell Death; CHO Cells; Cricetinae; Cycloheximide; Cysteine Proteinase Inhibitors; Eflornithine; Oxidoreductases Acting on CH-NH Group Donors; Polyamines; Putrescine; Spermidine; Spermine | 1997 |
Polyamine metabolism of rat gastric mucosa after oral administration of hypertonic sodium chloride solution.
Topics: Acetyltransferases; Administration, Oral; Animals; DNA Replication; Eflornithine; Enzyme Inhibitors; Gastric Mucosa; Male; Ornithine Decarboxylase; Oxidoreductases Acting on CH-NH Group Donors; Polyamine Oxidase; Polyamines; Putrescine; Rats; Rats, Wistar; Saline Solution, Hypertonic | 1998 |
Enhanced uptake of [3H] spermidine by 9L rat brain tumors after direct intratumoral infusion of inhibitors of enzymes of the polyamine biosynthetic pathway.
Topics: Adenosylmethionine Decarboxylase; Animals; Biological Transport; Body Weight; Brain Neoplasms; Corpus Striatum; Deoxyadenosines; Eflornithine; Enzyme Inhibitors; Gliosarcoma; Infusions, Parenteral; Male; Oxidoreductases Acting on CH-NH Group Donors; Putrescine; Rats; Rats, Inbred F344; Spermidine; Tritium; Tumor Cells, Cultured | 1999 |
The polyamine oxidase inhibitor MDL-72,527 selectively induces apoptosis of transformed hematopoietic cells through lysosomotropic effects.
Topics: Animals; Apoptosis; bcl-X Protein; Cell Cycle; Cell Death; Cell Line, Transformed; Cell Survival; Cell Transformation, Neoplastic; Eflornithine; Hematopoietic Stem Cells; Humans; Interleukin-3; Kinetics; Lysosomes; Mice; Oxidoreductases Acting on CH-NH Group Donors; Polyamine Oxidase; Polyamines; Proto-Oncogene Proteins c-bcl-2; Putrescine; Spermidine; Spermine | 1999 |
Effect of the polyamine oxidase inactivator MDL 72527 on N(1)-(n-octanesulfonyl)spermine toxicity.
Topics: Amine Oxidase (Copper-Containing); Animals; Caco-2 Cells; Calmodulin; Cell Cycle; Cell Death; Drug Synergism; Eflornithine; Guanidines; Humans; Molecular Structure; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Oxidoreductases Acting on CH-NH Group Donors; Polyamine Oxidase; Polyamines; Putrescine; Rats; Spermine; Sulfonamides; Trifluoperazine; Tumor Cells, Cultured | 2000 |
Contribution of spermidine to stimulation by hepatocyte growth factor in repair after damage of rabbit gastric mucosal cells in primary culture.
Topics: Animals; Cells, Cultured; DNA Repair; Eflornithine; Enzyme Inhibitors; Epithelial Cells; Gastric Mucosa; Hepatocyte Growth Factor; Putrescine; Rabbits; Spermidine; Wound Healing | 2003 |
Metabolic and antiproliferative consequences of activated polyamine catabolism in LNCaP prostate carcinoma cells.
Topics: Acetyl Coenzyme A; Acetyltransferases; Adenosylmethionine Decarboxylase; Carcinoma; Cell Division; Deoxyadenosines; Eflornithine; Enzyme Inhibitors; Humans; Male; Methionine; Ornithine; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Oxidoreductases Acting on CH-NH Group Donors; Polyamine Oxidase; Polyamines; Prostatic Neoplasms; Putrescine; RNA, Messenger; S-Adenosylmethionine; Tetracyclines; Thionucleosides; Tumor Cells, Cultured | 2004 |
Spermidine is indispensable in differentiation of 3T3-L1 fibroblasts to adipocytes.
Topics: 3T3-L1 Cells; Adipocytes; Adipogenesis; Animals; Cell Differentiation; Cell Proliferation; Cell Shape; Eflornithine; Fibroblasts; Gene Expression Regulation; Glucose Transporter Type 4; Isomerism; Lipid Metabolism; Mice; Organ Specificity; Putrescine; Spermidine; Time Factors | 2010 |