mdl 29311 has been researched along with probucol in 8 studies
*Probucol: A drug used to lower LDL and HDL cholesterol yet has little effect on serum-triglyceride or VLDL cholesterol. (From Martindale, The Extra Pharmacopoeia, 30th ed, p993). [MeSH]
*Probucol: A drug used to lower LDL and HDL cholesterol yet has little effect on serum-triglyceride or VLDL cholesterol. (From Martindale, The Extra Pharmacopoeia, 30th ed, p993). [MeSH]
| Studies (mdl 29311) | Trials (mdl 29311) | Recent Studies (post-2010) (mdl 29311) | Studies (probucol) | Trials (probucol) | Recent Studies (post-2010) (probucol) |
|---|---|---|---|---|---|
| 9 | 0 | 0 | 1,488 | 174 | 317 |
| Protein | Taxonomy | mdl 29311 (IC50) | probucol (IC50) |
|---|---|---|---|
| NAD-dependent protein deacylase sirtuin-5, mitochondrial | Homo sapiens (human) | 1.6 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 7 (87.50) | 18.2507 |
| 2000's | 1 (12.50) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Jackson, RL; Mao, SJ; Rechtin, AE; Van Sickle, WA; Yates, MT | 1 |
| Brake, N; Hagaman, KA; McLean, LR | 1 |
| Barnhart, RL; Jackson, RL; Robinson, KM; Sheetz, MJ | 1 |
| Dillberger, JE; Heineke, EW; Johnson, MB; Robinson, KM | 1 |
| Buzzetti, R; Chersi, A; Giovannini, C; Nisticò, L; Osborn, JF; Sorrentino, R | 1 |
| Barnhart, RL; Heineke, EW; Johnson, MB; Rhinehart, BL; Robinson, KM; Sheetz, MJ | 1 |
| Sheetz, MJ | 1 |
| Doggrell, SA | 1 |
8 other study(ies) available for mdl 29311 and probucol
| Article | Year |
|---|---|
Antioxidant activity of probucol and its analogues in hypercholesterolemic Watanabe rabbits.
Topics: Animals; Anticholesteremic Agents; Antioxidants; Cells, Cultured; Cholesterol; Hyperlipoproteinemia Type II; Indicators and Reagents; Lipid Peroxidation; Lipoproteins, LDL; Macrophages; Mice; Mice, Inbred Strains; Molecular Structure; Probucol; Rabbits; Structure-Activity Relationship | 1991 |
Interactions of MDL 29,311 and probucol metabolites with cholesteryl esters.
Topics: Animals; Carcinoma, Hepatocellular; Cholesterol Esters; Crystallization; Drug Interactions; Probucol; Rats; Tumor Cells, Cultured | 1994 |
MDL 29311, an analog of probucol, decreases triglycerides in rats by increasing hepatic clearance of very-low-density lipoprotein.
Topics: Animals; Cholesterol; Hypolipidemic Agents; Lipoproteins; Lipoproteins, VLDL; Liver; Male; Probucol; Rats; Rats, Sprague-Dawley; Time Factors; Triglycerides | 1994 |
Antioxidant MDL 29,311 prevents diabetes in nonobese diabetic and multiple low-dose STZ-injected mice.
Topics: Aging; Animals; Antioxidants; Atrophy; Blood Glucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Female; Insulin; Islets of Langerhans; Male; Mice; Mice, Inbred NOD; Mice, Inbred Strains; Pancreatic Diseases; Probucol | 1993 |
HLA-DQA1 and DQB1 gene polymorphisms in type I diabetic patients from central Italy and their use for risk prediction.
Topics: Adolescent; Alleles; Base Sequence; Diabetes Mellitus, Type 1; Female; HLA-DQ alpha-Chains; HLA-DQ Antigens; HLA-DQ beta-Chains; Humans; Incidence; Italy; Male; Molecular Sequence Data; Odds Ratio; Polymorphism, Genetic; Predictive Value of Tests; Prevalence; Probucol; Risk | 1993 |
MDL 29311. Antioxidant with marked lipid- and glucose-lowering activity in diabetic rats and mice.
Topics: Animals; Diabetes Mellitus, Experimental; Fasting; Fatty Acids, Nonesterified; Female; Hypoglycemic Agents; Hypolipidemic Agents; Insulin; Male; Mice; Mice, Inbred C57BL; Probucol; Rats; Rats, Sprague-Dawley; Time Factors; Triglycerides | 1993 |
MDL 29311, a phenolic antioxidant, interferes with the interaction of apoC with VLDL: a possible explanation for its triglyceride-lowering effect.
Topics: Animals; Apolipoproteins C; Apolipoproteins E; Cholesterol; Chromatography, Gel; Hypolipidemic Agents; Lipoproteins, VLDL; Male; Probucol; Rats; Rats, Sprague-Dawley; Triglycerides | 1995 |
Immunomodulation with DiNAC-- a new approach to the treatment of atherosclerosis?
Topics: Adjuvants, Immunologic; Animals; Arteriosclerosis; Benzhydryl Compounds; Cystine; Dermatitis, Contact; Mice; Mice, Inbred BALB C; Phenols; Probucol; Rabbits | 2002 |