mdl-25637 and validamycins

mdl-25637 has been researched along with validamycins* in 1 studies

Other Studies

1 other study(ies) available for mdl-25637 and validamycins

ArticleYear
Time-dependent inhibition of porcine kidney trehalase by aminosugars.
    FEBS letters, 1990, Mar-26, Volume: 262, Issue:2

    The inhibitory effects of various nitrogen-containing sugars on porcine kidney trehalase were studied. Validamycin A, validoxylamine A and MDL 25,637 were found to be potent, time-dependent inhibitors of the enzyme in vitro. The validoxylamine A-inhibited enzyme showed slow but reversible reactivation over time (t1/2 = 1.2 h). To our knowledge, this is the first report of time-dependent inhibition exhibited by either these particular aminosugars or a trehalase.

    Topics: Amino Sugars; Animals; In Vitro Techniques; Inositol; Kidney; Kinetics; Substrate Specificity; Sugar Alcohols; Swine; Trehalase; Trehalose

1990