Page last updated: 2024-09-03

mdl-201112 and adenosine

mdl-201112 has been researched along with adenosine in 3 studies

Compound Research Comparison

Studies
(mdl-201112)
Trials
(mdl-201112)
Recent Studies (post-2010)
(mdl-201112)
Studies
(adenosine)
Trials
(adenosine)
Recent Studies (post-2010) (adenosine)
100032,5361,0758,930

Protein Interaction Comparison

ProteinTaxonomymdl-201112 (IC50)adenosine (IC50)
high affinity choline transporter 1 isoform aHomo sapiens (human)0.3851
Sodium/nucleoside cotransporter 1Homo sapiens (human)5.5
Sodium/nucleoside cotransporter 2Homo sapiens (human)5.5
Adenosine receptor A3Homo sapiens (human)0.0011
Adenosine receptor A1Homo sapiens (human)0.0023
Equilibrative nucleoside transporter 1Homo sapiens (human)63
Solute carrier family 28 member 3Homo sapiens (human)3.3

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Borcherding, DR; Bowlin, TL; Edwards, CK; Hoffman, PF; Munson, HR; Peet, NP; Zhang, H1
Borcherding, DR; Edwards, CK; Linnik, MD; Long, RE; Parmely, MJ; Watts, LM1
Borcherding, DR; Edwards, CK; Morrison, DC; Parmely, MJ; Silverstein, R; Zhou, WW1

Other Studies

3 other study(ies) available for mdl-201112 and adenosine

ArticleYear
Carbocyclic nucleosides as inhibitors of human tumor necrosis factor-alpha production: effects of the stereoisomers of (3-hydroxycyclopentyl)adenines.
    Journal of medicinal chemistry, 1996, Jun-21, Volume: 39, Issue:13

    Topics: Adenine; Adenosine; Animals; Cyclopentanes; Galactosamine; Humans; Interleukin-1; Interleukin-6; Lipopolysaccharides; Macrophages; Magnetic Resonance Spectroscopy; Mice; Molecular Structure; Stereoisomerism; Tumor Necrosis Factor-alpha

1996
Effect of the carbocyclic nucleoside analogue MDL 201,112 on inhibition of interferon-gamma-induced priming of Lewis (LEW/N) rat macrophages for enhanced respiratory burst and MHC class II Ia+ antigen expression.
    Journal of leukocyte biology, 1994, Volume: 56, Issue:2

    Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Animals; Bordetella pertussis; Brain; Dipyridamole; Down-Regulation; Female; Histocompatibility Antigens Class II; Interferon-gamma; Kinetics; Lipopolysaccharides; Macrophage Activation; Macrophages, Peritoneal; Mycobacterium tuberculosis; Rats; Rats, Inbred Lew; Receptors, Purinergic P1; Receptors, Purinergic P2; Recombinant Proteins; Respiratory Burst; Stimulation, Chemical; Superoxides; Tumor Necrosis Factor-alpha; Zymosan

1994
Adenosine and a related carbocyclic nucleoside analogue selectively inhibit tumor necrosis factor-alpha production and protect mice against endotoxin challenge.
    Journal of immunology (Baltimore, Md. : 1950), 1993, Jul-01, Volume: 151, Issue:1

    Topics: Adenine; Adenosine; Animals; Cytokines; Endotoxins; Female; Interleukin-1; Macrophage Activation; Macrophages; Mice; Tumor Necrosis Factor-alpha

1993