mdl-201053 has been researched along with aloxistatin* in 2 studies
2 other study(ies) available for mdl-201053 and aloxistatin
Article | Year |
---|---|
Drug screening with human SMN2 reporter identifies SMN protein stabilizers to correct SMA pathology.
Spinal muscular atrophy (SMA), the leading genetic cause of infant mortality, is caused by reduced levels of functional survival motor neuron (SMN) protein. To identify therapeutic agents for SMA, we established a versatile SMN2-GFP reporter line by targeting the human Topics: Animals; Blood-Brain Barrier; Cysteine Proteinase Inhibitors; Dipeptides; Disease Models, Animal; Drug Evaluation, Preclinical; Genes, Reporter; HEK293 Cells; Humans; Ketones; Leucine; Mice; Mitochondria; Motor Neurons; Muscular Atrophy, Spinal; Protective Agents; Protein Stability; Proteolysis; Signal Transduction; Survival of Motor Neuron 2 Protein; Transfection; Treatment Outcome | 2019 |
Is cathepsin K truly involved in bone resorption?
Topics: Bone Resorption; Cathepsin K; Cathepsins; Cysteine Proteinase Inhibitors; Dipeptides; Humans; Ketones; Leucine; Osteoclasts | 1998 |