mdl 11939 has been researched along with piperidines in 35 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 11 (31.43) | 18.2507 |
| 2000's | 10 (28.57) | 29.6817 |
| 2010's | 13 (37.14) | 24.3611 |
| 2020's | 1 (2.86) | 2.80 |
| Authors | Studies |
|---|---|
| Belcher, PR; Drake-Holland, AJ; Hynd, J; Noble, MI | 1 |
| Ashby, CR; Edwards, E; Wang, RY | 1 |
| Baron, BM; Chi, EM; Harrison, BL; Kehne, JH; McCloskey, TC; Palfreyman, MG; Whitten, JP | 1 |
| Dage, RC; Koerner, JE | 1 |
| Carr, AA; Dage, RC; Li, T | 1 |
| Kreulen, DL; Meehan, AG | 1 |
| Abbate, GM; Nieduzak, TR; Schmidt, CJ; Taylor, VL | 1 |
| Abbate, GM; Black, CK; Schmidt, CJ; Taylor, VL | 1 |
| Cutler, NR; Robinson, RE; Sramek, JJ; Suri, A | 1 |
| Harvey, JA; Romano, AG; Welsh, SE | 1 |
| Harvey, JA; Hood, H; Romano, AG; Welsh, SE | 1 |
| Colado, MI; Elliott, JM; Esteban, B; Green, AR; Mechan, AO; O'Shea, E | 1 |
| Zhang, ZW | 1 |
| Aloyo, VJ; Harvey, JA; Liu, R; Quinn, JL; Romano, AG | 1 |
| Aloyo, VJ; Dave, KD; Fernando, GS; Harvey, JA; Quinn, JL | 1 |
| Grandoso, L; Pineda, J; Torrecilla, M; Ugedo, L | 1 |
| Alexander, G; Aloyo, VJ; Dave, KD; Harvey, JA; Liu, R; Quinn, JL; Romano, AG; Schwab, D | 1 |
| Aloyo, VJ; Dave, KD; Harvey, JA | 1 |
| Fox, MA; Gallagher, PS; Jensen, CL; Murphy, DL | 1 |
| Flaisher-Grinberg, S; Joel, D; Klavir, O | 1 |
| Buell, MR; Geyer, MA; Halberstadt, AL; Masten, VL; Risbrough, VB | 1 |
| Gamble, EH; Jia, M; Jiang, X; Li, H; Ursano, RJ; Zhang, S; Zhang, ZJ | 1 |
| Geyer, MA; Halberstadt, AL | 1 |
| Aloyo, VJ; Dougherty, JP | 1 |
| Bekinschtein, P; Garagoli, F; Katche, C; Medina, JH; Slipczuk, L; Tomaiuolo, M; Weisstaub, N | 1 |
| Elizalde, DI; Gallitano, AL; González-Maeso, J; Ingram, WM; Janowski, SA; Kamel, CM; Kozlenkov, A; Levine, S; Lish, JR; Resnik, J; Shoker, J; Williams, AA | 1 |
| Cooper, MA; Harvey, ML; Swallows, CL | 1 |
| Ásgeirsdóttir, HN; Barrera, MP; Cohen, SJ; Munchow, AH; Stackman, RW; Zhang, G | 1 |
| Grünblatt, E; Marinova, Z; Walitza, S | 1 |
| Bekinschtein, P; Gonzalez, MC; Renner, MC; Weisstaub, N | 1 |
| Bader, LR; Clinard, CT; Cooper, MA; Sullivan, MA | 1 |
| Amato, D; Carey, RJ; de Souza Silva, MA; Groos, D; Huston, JP; Lauber, AC; Müller, CP; Pum, ME | 1 |
| Hirai, T; Ishibashi, Y; Izumo, N; Tanaka, K; Togari, A | 1 |
| Cinalli, D; Stackman, RW; Zhang, G | 1 |
| Byun, JK; Chung, YH; Jeong, JH; Kim, HC; Ko, SK; Lee, Y; Nabeshima, T; Nah, SY; Nguyen, BT; Sharma, N; Shin, EJ | 1 |
1 trial(s) available for mdl 11939 and piperidines
| Article | Year |
|---|---|
Efficacy trial of the 5-HT2 antagonist MDL 11,939 in patients with generalized anxiety disorder.
Topics: Adult; Anxiety Disorders; Humans; Male; Piperidines; Serotonin Antagonists; Single-Blind Method | 1995 |
34 other study(ies) available for mdl 11939 and piperidines
| Article | Year |
|---|---|
Dispersion of coronary artery thrombi by antagonism of platelet serotonin receptor in the dog.
Topics: Animals; Blood Platelets; Blood Pressure; Coronary Thrombosis; Dogs; Epinephrine; Female; Male; Piperidines; Receptors, Serotonin; Regional Blood Flow; Serotonin Antagonists | 1992 |
Action of serotonin in the medial prefrontal cortex: mediation by serotonin3-like receptors.
Topics: Analysis of Variance; Animals; Benzamides; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Frontal Lobe; Indoles; Injections, Intravenous; Iontophoresis; Male; Metergoline; Pindolol; Piperidines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Ritanserin; Serotonin; Serotonin Antagonists; Spiperone; Tropisetron | 1992 |
NMDA receptor complex antagonists have potential anxiolytic effects as measured with separation-induced ultrasonic vocalizations.
Topics: 2-Amino-5-phosphonovalerate; Animals; Anti-Anxiety Agents; Anxiety, Separation; Behavior, Animal; Buspirone; Diazepam; Dioxins; Dizocilpine Maleate; Dose-Response Relationship, Drug; Indoles; Kynurenic Acid; Maternal Deprivation; Mephenesin; Piperidines; Quinolizines; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Serotonin; Serotonin Antagonists; Spiro Compounds; Valine; Vocalization, Animal | 1991 |
Antiarrhythmic and electrophysiologic effects of MDL 11,939, a novel class III antiarrhythmic agent in anesthetized dogs.
Topics: Animals; Anti-Arrhythmia Agents; Bretylium Compounds; Dogs; Drug Therapy, Combination; Electrocardiography; Electrophysiology; Female; Heart; Heart Ventricles; Male; Piperidines; Propranolol; Tachycardia; Ventricular Fibrillation | 1990 |
Effects of MDL 11,939 on action potential and contractile force in cardiac tissues: a comparison with bretylium, clofilium, and sotalol.
Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Bretylium Compounds; Dogs; Female; Guinea Pigs; In Vitro Techniques; Kinetics; Male; Microelectrodes; Myocardial Contraction; Papillary Muscles; Piperidines; Purkinje Fibers; Quaternary Ammonium Compounds; Reserpine; Sotalol | 1990 |
Electrophysiological studies on the interaction of 5-hydroxytryptamine with sympathetic transmission in the guinea pig inferior mesenteric artery and ganglion.
Topics: Animals; Cell Membrane; Female; Ganglia, Sympathetic; Guinea Pigs; Male; Membrane Potentials; Mesenteric Arteries; Methiothepin; Methysergide; Phentolamine; Piperidines; Serotonin; Serotonin Antagonists; Sympathetic Nervous System; Synaptic Transmission; Tropanes | 1991 |
5-HT2 antagonists stereoselectively prevent the neurotoxicity of 3,4-methylenedioxymethamphetamine by blocking the acute stimulation of dopamine synthesis: reversal by L-dopa.
Topics: 3,4-Dihydroxyphenylacetic Acid; 3,4-Methylenedioxyamphetamine; Animals; Anti-Arrhythmia Agents; Brain; Corpus Striatum; Dopamine; Dose-Response Relationship, Drug; Drug Synergism; Haloperidol; Homovanillic Acid; Levodopa; Male; Nomifensine; Piperidines; Rats; Rats, Inbred Strains; Ritanserin; Serotonin Antagonists; Stereoisomerism; Time Factors | 1991 |
Methylenedioxymethamphetamine-induced hyperthermia and neurotoxicity are independently mediated by 5-HT2 receptors.
Topics: 3,4-Methylenedioxyamphetamine; Animals; Body Temperature; Cerebral Cortex; Corpus Striatum; Haloperidol; Hippocampus; Male; N-Methyl-3,4-methylenedioxyamphetamine; Neurotoxins; Piperidines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Reference Values; Serotonin; Serotonin Antagonists | 1990 |
Effects of serotonin 5-HT(2A/2C) antagonists on associative learning in the rabbit.
Topics: Animals; Conditioning, Classical; Female; Male; Nictitating Membrane; Piperidines; Rabbits; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2C; Receptors, Serotonin; Ritanserin; Serotonin Antagonists | 1998 |
Effect of 5-HT2 receptor antagonists on a cranial nerve reflex in the rabbit: evidence for inverse agonism.
Topics: Animals; Cranial Nerves; Ergolines; Female; Ketanserin; Lysergic Acid Diethylamide; Male; Mianserin; Piperidines; Rabbits; Receptors, Serotonin; Reflex; Ritanserin; Serotonin Antagonists; Serotonin Receptor Agonists | 1999 |
The pharmacology of the acute hyperthermic response that follows administration of 3,4-methylenedioxymethamphetamine (MDMA, 'ecstasy') to rats.
Topics: 3,4-Methylenedioxyamphetamine; Acute Disease; Animals; Benzazepines; Body Temperature; Corpus Striatum; Dopamine; Dopamine Antagonists; Dopamine Uptake Inhibitors; Fever; Hallucinogens; Hippocampus; Male; Methysergide; N-Methyl-3,4-methylenedioxyamphetamine; Neuroprotective Agents; Piperazines; Piperidines; Rats; Rats, Inbred Strains; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2C; Receptors, Serotonin; Remoxipride; Ritanserin; Selective Serotonin Reuptake Inhibitors; Serotonin Antagonists | 2002 |
Serotonin induces tonic firing in layer V pyramidal neurons of rat prefrontal cortex during postnatal development.
Topics: Age Factors; Animals; Down-Regulation; Female; In Vitro Techniques; Ketanserin; Male; Membrane Potentials; Patch-Clamp Techniques; Piperidines; Prefrontal Cortex; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Signal Transduction | 2003 |
Selective remodeling of rabbit frontal cortex: relationship between 5-HT2A receptor density and associative learning.
Topics: Animals; Behavior, Animal; Blinking; Conditioning, Classical; Learning; Ligands; Lysergic Acid Diethylamide; Male; Piperidines; Prefrontal Cortex; Rabbits; Receptor, Serotonin, 5-HT2A; Serotonin 5-HT2 Receptor Agonists; Time Factors | 2004 |
Serotonin 5-HT2A receptors in the CA1 field of the hippocampus mediate head movements in the rabbit.
Topics: Amphetamines; Animals; Autoradiography; Diffusion; Dose-Response Relationship, Drug; Head Movements; Hippocampus; Immunohistochemistry; Injections; Male; Piperidines; Pyramidal Tracts; Rabbits; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2C; Serotonin Receptor Agonists | 2004 |
alpha(2)-Adrenoceptor involvement in the in vitro inhibitory effect of citalopram on a subpopulation of rat locus coeruleus neurons.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Action Potentials; Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Amphetamines; Animals; Bridged Bicyclo Compounds, Heterocyclic; Brimonidine Tartrate; Citalopram; Dose-Response Relationship, Drug; Duloxetine Hydrochloride; Idazoxan; In Vitro Techniques; Locus Coeruleus; Male; Methiothepin; Naloxone; Narcotic Antagonists; Neurons; Norepinephrine; Oxazines; Piperazines; Piperidines; Pyridines; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Receptors, Opioid, mu; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Thiophenes | 2005 |
Effect of serotonin depletion on 5-HT2A-mediated learning in the rabbit: evidence for constitutive activity of the 5-HT2A receptor in vivo.
Topics: 5,7-Dihydroxytryptamine; Animals; Biogenic Amines; Brain Chemistry; Conditioning, Eyelid; Immunohistochemistry; Learning; Lysergic Acid Diethylamide; Male; Nerve Endings; Piperidines; Rabbits; Radioligand Assay; Receptor, Serotonin, 5-HT2A; Serotonin; Serotonin Agents; Serotonin Antagonists; Serotonin Plasma Membrane Transport Proteins; Serotonin Receptor Agonists | 2006 |
The time-course for up- and down-regulation of the cortical 5-hydroxytryptamine (5-HT)2A receptor density predicts 5-HT2A receptor-mediated behavior in the rabbit.
Topics: Amphetamines; Animals; Behavior, Animal; Cerebral Cortex; Down-Regulation; Injections, Intraventricular; Male; Piperidines; Rabbits; Receptor, Serotonin, 5-HT2A; Serotonin 5-HT2 Receptor Antagonists; Serotonin Receptor Agonists; Up-Regulation | 2007 |
Receptor mediation of exaggerated responses to serotonin-enhancing drugs in serotonin transporter (SERT)-deficient mice.
Topics: 5-Hydroxytryptophan; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Behavior, Animal; Dose-Response Relationship, Drug; Female; Mice; Mice, Inbred C57BL; Mice, Knockout; Monoamine Oxidase Inhibitors; Piperazines; Piperidines; Polymorphism, Genetic; Pyridines; Receptors, Serotonin; Serotonin Antagonists; Serotonin Plasma Membrane Transport Proteins; Serotonin Receptor Agonists; Serotonin Syndrome; Tranylcypromine | 2007 |
The role of 5-HT2A and 5-HT2C receptors in the signal attenuation rat model of obsessive-compulsive disorder.
Topics: Amphetamines; Analysis of Variance; Animals; Behavior, Animal; Compulsive Behavior; Conditioning, Operant; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Combinations; Extinction, Psychological; Male; Obsessive-Compulsive Disorder; Piperidines; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2C; Serotonin 5-HT2 Receptor Antagonists; Spiro Compounds; Sulfonamides | 2008 |
Modification of the effects of 5-methoxy-N,N-dimethyltryptamine on exploratory behavior in rats by monoamine oxidase inhibitors.
Topics: Animals; Behavior, Animal; Behavioral Research; Clorgyline; DOM 2,5-Dimethoxy-4-Methylamphetamine; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Drug Therapy, Combination; Exploratory Behavior; Harmaline; Hyperkinesis; Male; Methoxydimethyltryptamines; Monoamine Oxidase Inhibitors; Motor Activity; Pattern Recognition, Automated; Pharmaceutical Vehicles; Piperazines; Piperidines; Psychotropic Drugs; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2A; Serotonin 5-HT1 Receptor Antagonists; Time Factors | 2008 |
5-HT2A receptor antagonism by MDL 11,939 during inescapable stress prevents subsequent exaggeration of acoustic startle response and reduced body weight in rats.
Topics: Animals; Body Weight; Disease Models, Animal; Dose-Response Relationship, Drug; Helplessness, Learned; Male; Piperidines; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2A; Reflex, Startle; Serotonin 5-HT2 Receptor Antagonists; Stress, Psychological | 2011 |
LSD but not lisuride disrupts prepulse inhibition in rats by activating the 5-HT(2A) receptor.
Topics: Acoustic Stimulation; Animals; Behavior, Animal; Dopamine Agonists; Dopamine Antagonists; Dose-Response Relationship, Drug; Hallucinogens; Lisuride; Lysergic Acid Diethylamide; Male; Piperazines; Piperidines; Pyridines; Raclopride; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D2; Receptors, Dopamine D3; Reflex, Startle; Serotonin 5-HT2 Receptor Agonists; Serotonin 5-HT2 Receptor Antagonists; Serotonin Antagonists; Serotonin Receptor Agonists | 2010 |
Pharmacological and behavioral characterization of the 5-HT2A receptor in C57BL/6N mice.
Topics: Amphetamines; Animals; Cerebral Cortex; Humans; Ligands; Male; Mice; Mice, Inbred C57BL; Piperidines; Protein Binding; Rabbits; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2C; Serotonin Antagonists; Serotonin Receptor Agonists; Species Specificity | 2011 |
Attenuating the persistence of fear memory storage using a single dose of antidepressant.
Topics: Analysis of Variance; Animals; Antidepressive Agents, Second-Generation; Avoidance Learning; Brain-Derived Neurotrophic Factor; Conditioning, Classical; Cyclohexanols; Fear; Hippocalcin; Male; Memory; Mice; Mice, Knockout; Piperidines; Rats; Rats, Wistar; Reaction Time; Receptor, Serotonin, 5-HT2A; Serotonin; Serotonin Antagonists; Time Factors; Venlafaxine Hydrochloride | 2013 |
Reduced levels of serotonin 2A receptors underlie resistance of Egr3-deficient mice to locomotor suppression by clozapine.
Topics: Animals; Clozapine; Disease Models, Animal; Early Growth Response Protein 3; Humans; Hypnotics and Sedatives; Ketanserin; Male; Mice; Mice, Transgenic; Motor Activity; Piperidines; Receptor, Serotonin, 5-HT2A; Schizophrenia; Serotonin 5-HT2 Receptor Agonists; Serotonin Antagonists | 2012 |
A double dissociation in the effects of 5-HT2A and 5-HT2C receptors on the acquisition and expression of conditioned defeat in Syrian hamsters.
Topics: Analysis of Variance; Animals; Conditioning, Psychological; Cricetinae; Disease Models, Animal; Dominance-Subordination; Male; Mesocricetus; Piperazines; Piperidines; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2C; Serotonin Antagonists; Serotonin Receptor Agonists; Stress, Psychological | 2012 |
Stimulation of serotonin 2A receptors facilitates consolidation and extinction of fear memory in C57BL/6J mice.
Topics: Animals; Anti-Anxiety Agents; Anxiety; Anxiety Disorders; Bridged Bicyclo Compounds; Cues; Extinction, Psychological; Fear; Male; Memory; Memory, Episodic; Methylamines; Mice; Mice, Inbred C57BL; Molecular Targeted Therapy; Nerve Tissue Proteins; Nootropic Agents; Piperidines; Receptor, Serotonin, 5-HT2A; Recognition, Psychology; Reinforcement, Psychology; Serotonin 5-HT2 Receptor Agonists; Serotonin 5-HT2 Receptor Antagonists | 2013 |
5-HT2A serotonin receptor agonist DOI alleviates cytotoxicity in neuroblastoma cells: role of the ERK pathway.
Topics: Amphetamines; Cell Line, Tumor; Cell Proliferation; Culture Media, Serum-Free; Dose-Response Relationship, Drug; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Humans; MAP Kinase Signaling System; Neuroblastoma; Organic Chemicals; Piperidines; Receptor, EphB3; Receptor, Serotonin, 5-HT2A; RNA, Messenger; Serotonin Antagonists; Serotonin Receptor Agonists; Time Factors | 2013 |
Role of medial prefrontal cortex serotonin 2A receptors in the control of retrieval of recognition memory in rats.
Topics: Animals; Attention; Behavior, Animal; Cues; Discrimination, Psychological; Male; Mental Recall; Piperidines; Prefrontal Cortex; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT2A; Recognition, Psychology; Serotonin 5-HT2 Receptor Antagonists | 2013 |
Activation of 5-HT2a receptors in the basolateral amygdala promotes defeat-induced anxiety and the acquisition of conditioned defeat in Syrian hamsters.
Topics: Animals; Anxiety; Avoidance Learning; Basolateral Nuclear Complex; Bridged Bicyclo Compounds; Conditioning, Psychological; Dominance-Subordination; Dose-Response Relationship, Drug; Fear; Male; Memory; Mesocricetus; Methylamines; Piperidines; Receptor, Serotonin, 5-HT2A; Serotonin 5-HT2 Receptor Agonists; Serotonin 5-HT2 Receptor Antagonists | 2015 |
Neuropharmacology of light-induced locomotor activation.
Topics: Animals; Dopamine Agents; Dose-Response Relationship, Drug; Excitatory Amino Acid Agents; Haloperidol; Indoles; Ketamine; Light; Male; Motor Activity; Naphthyridines; Phencyclidine; Photic Stimulation; Piperazines; Piperidines; Pyridines; Quinpirole; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Ritanserin; Serotonin Antagonists | 2015 |
Modulation of osteoblast differentiation and bone mass by 5-HT2A receptor signaling in mice.
Topics: 3T3 Cells; Animals; Cell Differentiation; Femur; Gene Expression Regulation; Male; Mice; Mice, Inbred C57BL; Organ Size; Osteoblasts; Osteogenesis; Piperidines; Receptor, Serotonin, 5-HT2A; Serotonin 5-HT2 Receptor Antagonists; Signal Transduction | 2015 |
Effect of a hallucinogenic serotonin 5-HT
Topics: Action Potentials; Animals; Bridged Bicyclo Compounds; CA1 Region, Hippocampal; Cognition; Cues; Exploratory Behavior; Goals; Hallucinogens; Male; Maze Learning; Methylamines; Mice, Inbred C57BL; Neurons; Neuropsychological Tests; Piperidines; Receptor, Serotonin, 5-HT2A; Serotonin 5-HT2 Receptor Agonists; Serotonin 5-HT2 Receptor Antagonists; Space Perception; Swimming; Visual Perception | 2017 |
Ginsenoside Re Protects against Serotonergic Behaviors Evoked by 2,5-Dimethoxy-4-iodo-amphetamine in Mice via Inhibition of PKCδ-Mediated Mitochondrial Dysfunction.
Topics: Acetophenones; Amphetamines; Animals; Behavior, Animal; Benzopyrans; Ginsenosides; Hypothalamus; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mitochondria; Oxidative Stress; Piperidines; Protein Kinase C-delta; Protein Kinase Inhibitors; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Serotonin Syndrome | 2021 |