mdl 100240 has been researched along with bradykinin in 4 studies
| Studies (mdl 100240) | Trials (mdl 100240) | Recent Studies (post-2010) (mdl 100240) | Studies (bradykinin) | Trials (bradykinin) | Recent Studies (post-2010) (bradykinin) |
|---|---|---|---|---|---|
| 21 | 9 | 0 | 14,195 | 355 | 1,520 |
| Protein | Taxonomy | mdl 100240 (IC50) | bradykinin (IC50) |
|---|---|---|---|
| B2 bradykinin receptor | Homo sapiens (human) | 0.0018 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (75.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Anderson, B; Beach, DC; Dage, RC; Flynn, GA; French, JF; Giroux, EL; Koehl, JR; Mehdi, S | 1 |
| Bennett, T; Brunner-Ferber, F; Gardiner, SM; Kemp, PA | 2 |
| Agabiti-Rosei, E; Bianchi, R; De Ciuceis, C; Nussdorfer, GG; Paiardi, S; Porteri, E; Rezzani, R; Rizzoni, D; Rodella, L; Rossi, GP; Sleiman, I; Sticchi, D | 1 |
4 other study(ies) available for mdl 100240 and bradykinin
| Article | Year |
|---|---|
Characterization of a dual inhibitor of angiotensin I-converting enzyme and neutral endopeptidase.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Atrial Natriuretic Factor; Benzazepines; Bradykinin; Male; Molecular Structure; Neprilysin; Peptidyl-Dipeptidase A; Prodrugs; Pyridines; Rats; Rats, Sprague-Dawley | 1994 |
Effects of the dual metallopeptidase inhibitor, MDL 100,240, on regional haemodynamic responses to vasoactive peptides in conscious rats.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Atrial Natriuretic Factor; Benzazepines; Bradykinin; Endothelin-1; Hemodynamics; Male; Neprilysin; Protease Inhibitors; Pyridines; Rats | 1997 |
Comparative effects of the dual metallopeptidase inhibitor, MDL 100,240 and of enalaprilat on regional and on cardiac haemodynamics in conscious, hypertensive, transgenic ((mRen-2)27) rats.
Topics: Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Animals, Genetically Modified; Benzazepines; Bradykinin; Enalaprilat; Hemodynamics; Hypertension; Male; Metalloendopeptidases; Protease Inhibitors; Pyridines; Rats | 1997 |
Bradykinin and matrix metalloproteinases are involved the structural alterations of rat small resistance arteries with inhibition of ACE and NEP.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Animals, Genetically Modified; Benzazepines; Bradykinin; Bradykinin Receptor Antagonists; Disease Models, Animal; Drug Interactions; Hypertension; Immunohistochemistry; Male; Matrix Metalloproteinases; Mesenteric Arteries; Myography; Neprilysin; Pyridines; Ramipril; Rats; Rats, Sprague-Dawley; Tissue Inhibitor of Metalloproteinase-1; Tissue Inhibitor of Metalloproteinase-2; Vascular Resistance; Vasoconstriction | 2004 |