Page last updated: 2024-09-04

mdl 100173 and captopril

mdl 100173 has been researched along with captopril in 1 studies

*Captopril: A potent and specific inhibitor of PEPTIDYL-DIPEPTIDASE A. It blocks the conversion of ANGIOTENSIN I to ANGIOTENSIN II, a vasoconstrictor and important regulator of arterial blood pressure. Captopril acts to suppress the RENIN-ANGIOTENSIN SYSTEM and inhibits pressure responses to exogenous angiotensin. [MeSH]

*Captopril: A potent and specific inhibitor of PEPTIDYL-DIPEPTIDASE A. It blocks the conversion of ANGIOTENSIN I to ANGIOTENSIN II, a vasoconstrictor and important regulator of arterial blood pressure. Captopril acts to suppress the RENIN-ANGIOTENSIN SYSTEM and inhibits pressure responses to exogenous angiotensin. [MeSH]

Compound Research Comparison

Studies
(mdl 100173)
Trials
(mdl 100173)
Recent Studies (post-2010)
(mdl 100173)
Studies
(captopril)
Trials
(captopril)
Recent Studies (post-2010) (captopril)
72010,3201,514890

Protein Interaction Comparison

ProteinTaxonomymdl 100173 (IC50)captopril (IC50)
Leukotriene A-4 hydrolaseHomo sapiens (human)3.6
Angiotensin-converting enzyme Homo sapiens (human)0.084
Angiotensin-converting enzymeOryctolagus cuniculus (rabbit)0.0173
Succinyl-diaminopimelate desuccinylaseHaemophilus influenzae Rd KW203.3
Angiotensin-converting enzymeRattus norvegicus (Norway rat)0.1004
Beta-lactamase Pseudomonas aeruginosa5
Angiotensin-converting enzyme 2 Homo sapiens (human)0.011
Beta-lactamase class B VIM-2 Pseudomonas aeruginosa3.5

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Anderson, BA; Dage, RC; Downs, TR; French, JF1

Other Studies

1 other study(ies) available for mdl 100173 and captopril

ArticleYear
Dual inhibition of angiotensin-converting enzyme and neutral endopeptidase in rats with hypertension.
    Journal of cardiovascular pharmacology, 1995, Volume: 26, Issue:1

    Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Atrial Natriuretic Factor; Benzazepines; Blood Pressure; Captopril; Disease Models, Animal; Diuresis; Hypertension; Hypertension, Renal; Male; Neprilysin; Protease Inhibitors; Pyridines; Rats; Rats, Inbred SHR; Rats, Sprague-Dawley; Sodium

1995