md 780236 has been researched along with selegiline in 3 studies
| Studies (md 780236) | Trials (md 780236) | Recent Studies (post-2010) (md 780236) | Studies (selegiline) | Trials (selegiline) | Recent Studies (post-2010) (selegiline) |
|---|---|---|---|---|---|
| 12 | 0 | 0 | 2,575 | 319 | 394 |
| Protein | Taxonomy | md 780236 (IC50) | selegiline (IC50) |
|---|---|---|---|
| Cholinesterase | Homo sapiens (human) | 0.0055 | |
| Cytochrome P450 3A4 | Homo sapiens (human) | 0.0039 | |
| Alpha-2A adrenergic receptor | Homo sapiens (human) | 1.798 | |
| Alpha-2B adrenergic receptor | Homo sapiens (human) | 0.376 | |
| Amine oxidase [flavin-containing] B | Rattus norvegicus (Norway rat) | 0.2127 | |
| Amine oxidase [flavin-containing] A | Rattus norvegicus (Norway rat) | 0.9046 | |
| Amine oxidase [flavin-containing] A | Homo sapiens (human) | 1.4408 | |
| Adenosine receptor A1 | Rattus norvegicus (Norway rat) | 0.0067 | |
| Amine oxidase [flavin-containing] B | Homo sapiens (human) | 0.1001 | |
| Type-1 angiotensin II receptor | Sus scrofa (pig) | 0.048 | |
| Alpha-synuclein | Homo sapiens (human) | 0.27 | |
| Amine oxidase [flavin-containing] B | Bos taurus (cattle) | 1 | |
| Sigma intracellular receptor 2 | Rattus norvegicus (Norway rat) | 0.017 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Greenshaw, AJ; Turkish, S; Yu, PH | 1 |
| Boucher, T; Dostert, P; Dow, J; Strolin Benedetti, M | 1 |
| Benedetti, MS; Dostert, P; Guffroy, C; Tipton, KF | 1 |
3 other study(ies) available for md 780236 and selegiline
| Article | Year |
|---|---|
Monoamine oxidase-B inhibition: a comparison of in vivo and ex vivo measures of reversible effects.
Topics: Animals; Drug Interactions; In Vitro Techniques; Male; Monoamine Oxidase; Motor Activity; Oxazoles; Oxazolidinones; Phenethylamines; Rats; Rats, Inbred Strains; Selegiline; Time Factors | 1988 |
Metabolism of the monoamine oxidase-B inhibitor, MD 780236 and its enantiomers by the A and B forms of the enzyme in the rat.
Topics: Animals; Biotransformation; Brain; Clorgyline; In Vitro Techniques; Liver; Male; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Oxazoles; Oxazolidinones; Rats; Rats, Inbred Strains; Selegiline; Stereoisomerism | 1983 |
Partial or total protection from long-acting monoamine oxidase inhibitors (MAOIs) by new short-acting MAOIs of type A MD780515 and type B MD780236.
Topics: Animals; Brain; Clorgyline; Dose-Response Relationship, Drug; Female; Liver; Male; Monoamine Oxidase Inhibitors; Myocardium; Oxazoles; Oxazolidinones; Rats; Rats, Inbred Strains; Selegiline; Tranylcypromine | 1983 |