Compounds > mcn 5691
Page last updated: 2024-09-03

mcn 5691 and diltiazem

mcn 5691 has been researched along with diltiazem in 2 studies

Compound Research Comparison

Studies
(mcn 5691)		Trials
(mcn 5691)		Recent Studies (post-2010)
(mcn 5691)		Studies
(diltiazem)		Trials
(diltiazem)		Recent Studies (post-2010) (diltiazem)
7006,4021,073578

Protein Interaction Comparison

ProteinTaxonomymcn 5691 (IC50)diltiazem (IC50)
Voltage-dependent L-type calcium channel subunit alpha-1CCavia porcellus (domestic guinea pig)0.45
Voltage-dependent L-type calcium channel subunit alpha-1FHomo sapiens (human)0.605
Cytochrome P450 3A4Homo sapiens (human)1.8366
Voltage-dependent L-type calcium channel subunit alpha-1CRattus norvegicus (Norway rat)0.896
Voltage-dependent L-type calcium channel subunit alpha-1DRattus norvegicus (Norway rat)0.896
Sodium channel protein type 1 subunit alphaHomo sapiens (human)9
Sodium channel protein type 4 subunit alphaHomo sapiens (human)9
Sodium channel protein type 7 subunit alphaHomo sapiens (human)9
Voltage-dependent L-type calcium channel subunit alpha-1D Homo sapiens (human)0.605
Voltage-dependent L-type calcium channel subunit alpha-1SRattus norvegicus (Norway rat)0.896
Voltage-dependent L-type calcium channel subunit alpha-1SHomo sapiens (human)0.605
Voltage-dependent L-type calcium channel subunit alpha-1CHomo sapiens (human)0.605
Sodium channel protein type 5 subunit alphaHomo sapiens (human)9
Sodium channel protein type 9 subunit alphaHomo sapiens (human)9
Sodium channel protein type 2 subunit alphaHomo sapiens (human)9
Sodium channel protein type 3 subunit alphaHomo sapiens (human)9
Sodium channel protein type 11 subunit alphaHomo sapiens (human)9
Sodium channel protein type 8 subunit alphaHomo sapiens (human)9
Sodium channel protein type 10 subunit alphaHomo sapiens (human)9

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19901 (50.00)18.7374
1990's0 (0.00)18.2507
2000's1 (50.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Almond, HR; Brannan, MD; Carmosin, RJ; Carson, JR; Flaim, SF; Gill, A; Gleason, MM; Keely, SL; Ludovici, DW; Pitis, PM1
Schleifer, KJ; Tot, E1

Other Studies

2 other study(ies) available for mcn 5691 and diltiazem

ArticleYear
2-Ethynylbenzenealkanamines. A new class of calcium entry blockers.
    Journal of medicinal chemistry, 1988, Volume: 31, Issue:3

    Topics: Alkynes; Amines; Animals; Calcium Channel Blockers; Coronary Circulation; Guinea Pigs; Hypertension; Rats; Rats, Inbred SHR; Structure-Activity Relationship; Vasodilation

1988
Pharmacophore modelling of structurally unusual diltiazem mimics at L-type calcium channels.
    Journal of computer-aided molecular design, 2000, Volume: 14, Issue:5

    Topics: Binding Sites; Calcium Channel Blockers; Calcium Channels, L-Type; Computer Simulation; Diltiazem; DOM 2,5-Dimethoxy-4-Methylamphetamine; In Vitro Techniques; Isoquinolines; Models, Molecular; Molecular Conformation; Oximes; Papaverine; Propylamines; Static Electricity

2000