Page last updated: 2024-08-26

mci 9038 and dabigatran

mci 9038 has been researched along with dabigatran in 24 studies

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (8.33)29.6817
2010's19 (79.17)24.3611
2020's3 (12.50)2.80

Authors

AuthorsStudies
Dong, MH; Li, ML; Ren, WX; Ren, YJ1
Chen, D; Diao, X; Gong, G; Han, X; Shen, H; Wang, S; Wang, Y; Xu, Y; Zhu, Q1
Chen, D; Cui, S; Deng, X; Gong, G; Liu, J; Shi, J; Xu, Y; Yang, Y; Zhang, X; Zhu, Q1
Bai, T; Feng, Q; Guo, T; Jia, J; Li, X; Liu, Y; Pei, J; Song, Y; Wu, L; Wu, S; Zhang, Y; Zheng, X1
Büller, HR; Di Nisio, M; Middeldorp, S1
Chevalier, A; Nutescu, EA; Shapiro, NL1
Jiang, X; Wong, PC1
Ansell, JE; Lee, CJ1
Ageno, W; Streif, W1
Bark, N; Blombäck, M; He, S; Wallèn, H1
Fritsma, GA1
Azuma, S; Lum, CJ1
Alban, S; Birschmann, I; Busse, J; Dittrich, M; Eller, T; Flieder, T; Knabbe, C1
Boyle, ME; Fisher, S; Ishimoto, J; Kiser, TH; Lind, SE; Trujillo, TC1
Carrieri, C; Colucci, M; Incampo, F; Semeraro, N1
Kadauke, S; Khor, B; Van Cott, EM1
Li, M; Ren, Y1
Fujimori, Y; Katagiri, H; Murata, M; Ohira, K; Shimizu, N; Wakui, M1
Arachchillage, DR; Baglin, T; Besser, M; Maclean, R; van Veen, JJ1
Fredenburgh, JC; Leslie, BA; Stafford, AR; Weitz, JI; Yeh, CH1
Gheysens, O; Goffin, KE; Hoylaerts, MF; Jacquemin, M; Liesenborghs, L; Peerlinck, K; Peetermans, M; Peetermans, WE; Vanassche, T; Verhaegen, J; Verhamme, P; Wijngaerden, EV1
Cornelius, CC; Cripps, MW; Gales, PE; Nakonezny, PA; Vazquez, N; Wey, JC1
Fu, G; Liu, Z; Wang, Y; Yin, L; Zhang, K1
Beyer-Westendorf, J; Brückner, L; Pietsch, J; Tiebel, O1

Reviews

4 review(s) available for mci 9038 and dabigatran

ArticleYear
Progress of thrombus formation and research on the structure-activity relationship for antithrombotic drugs.
    European journal of medicinal chemistry, 2022, Jan-15, Volume: 228

    Topics: Fibrinolytic Agents; Humans; Molecular Structure; Thrombosis

2022
New anticoagulant agents: direct thrombin inhibitors.
    Cardiology clinics, 2008, Volume: 26, Issue:2

    Topics: Anticoagulants; Arginine; Atrial Fibrillation; Benzimidazoles; Dabigatran; Fibrinolytic Agents; Half-Life; Hirudins; Humans; Peptide Fragments; Pipecolic Acids; Pyridines; Recombinant Proteins; Stroke; Sulfonamides; Thrombin

2008
Direct thrombin inhibitors.
    British journal of clinical pharmacology, 2011, Volume: 72, Issue:4

    Topics: Anticoagulants; Antithrombins; Arginine; Benzimidazoles; Dabigatran; Hirudins; Humans; Peptide Fragments; Pipecolic Acids; Pyridines; Recombinant Proteins; Sulfonamides; Thrombin; Venous Thromboembolism

2011
Direct thrombin and factor Xa inhibitors in children: a quest for new anticoagulants for children.
    Wiener medizinische Wochenschrift (1946), 2011, Volume: 161, Issue:3-4

    Topics: Adolescent; Anticoagulants; Arginine; Benzimidazoles; beta-Alanine; Child; Child, Preschool; Dabigatran; Drug Approval; Factor Xa Inhibitors; Fondaparinux; Hirudins; Humans; Infant; Infant, Newborn; Morpholines; Peptide Fragments; Pipecolic Acids; Polysaccharides; Recombinant Proteins; Risk Factors; Rivaroxaban; Sulfonamides; Thiophenes; Thrombin; Venous Thromboembolism

2011

Trials

1 trial(s) available for mci 9038 and dabigatran

ArticleYear
Targeting Coagulase Activity in Staphylococcus aureus Bacteraemia: A Randomized Controlled Single-Centre Trial of Staphylothrombin Inhibition.
    Thrombosis and haemostasis, 2018, Volume: 118, Issue:5

    Topics: Administration, Intravenous; Administration, Oral; Aged; Aged, 80 and over; Anticoagulants; Antithrombins; Arginine; Bacteremia; Belgium; Blood Coagulation; Coagulase; Dabigatran; Enoxaparin; Feasibility Studies; Female; Hemorrhage; Humans; Injections, Subcutaneous; Male; Middle Aged; Partial Thromboplastin Time; Pilot Projects; Pipecolic Acids; Prospective Studies; Staphylococcal Infections; Staphylococcus aureus; Sulfonamides; Thrombin; Thrombosis; Time Factors; Treatment Outcome

2018

Other Studies

19 other study(ies) available for mci 9038 and dabigatran

ArticleYear
Design, synthesis and structural exploration of novel fluorinated dabigatran derivatives as direct thrombin inhibitors.
    European journal of medicinal chemistry, 2015, Volume: 96

    Topics: Animals; Anticoagulants; Antithrombins; Blood Coagulation; Dabigatran; Dose-Response Relationship, Drug; Drug Design; Humans; Hydrocarbons, Fluorinated; Molecular Structure; Platelet Aggregation; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship; Thrombin

2015
Design, synthesis and antithrombotic evaluation of novel dabigatran etexilate analogs, a new series of non-peptides thrombin inhibitors.
    Bioorganic & medicinal chemistry, 2015, Dec-01, Volume: 23, Issue:23

    Topics: Animals; Anticoagulants; Dabigatran; Humans; Male; Mice; Molecular Docking Simulation; Platelet Aggregation Inhibitors; Prodrugs; Rabbits; Rats; Rats, Sprague-Dawley; Thrombin

2015
Design, synthesis and antithrombotic evaluation of novel non-peptide thrombin inhibitors.
    Bioorganic & medicinal chemistry, 2017, 01-15, Volume: 25, Issue:2

    Topics: Animals; Dose-Response Relationship, Drug; Drug Design; Fibrinolytic Agents; Humans; Male; Molecular Structure; Platelet Aggregation; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship; Thrombin; Venous Thrombosis

2017
Direct thrombin inhibitors.
    The New England journal of medicine, 2005, Sep-08, Volume: 353, Issue:10

    Topics: Angioplasty, Balloon, Coronary; Anticoagulants; Antithrombins; Arginine; Benzimidazoles; Blood Coagulation; Dabigatran; Heart Diseases; Heparin; Humans; Pipecolic Acids; Prodrugs; Pyridines; Sulfonamides; Thrombin; Thromboembolism; Thrombosis; Venous Thrombosis

2005
Apixaban, a direct factor Xa inhibitor, inhibits tissue-factor induced human platelet aggregation in vitro: comparison with direct inhibitors of factor VIIa, XIa and thrombin.
    Thrombosis and haemostasis, 2010, Volume: 104, Issue:2

    Topics: Adenosine Diphosphate; Anticoagulants; Arginine; Azetidines; Benzimidazoles; Collagen; Dabigatran; Dose-Response Relationship, Drug; Factor VIIa; Factor Xa; Factor Xa Inhibitors; Factor XIa; Humans; Morpholines; Pipecolic Acids; Piperazines; Platelet Aggregation; Platelet Aggregation Inhibitors; Pyrazoles; Pyridines; Pyridones; Rivaroxaban; Sulfonamides; Thiophenes; Thrombin; Thromboplastin; Time Factors

2010
In vitro studies using a global hemostasis assay to examine the anticoagulation effects in plasma by the direct thrombin inhibitors: dabigatran and argatroban.
    Journal of thrombosis and thrombolysis, 2013, Volume: 35, Issue:2

    Topics: Aged; Anticoagulants; Antithrombins; Arginine; Benzimidazoles; beta-Alanine; Blood Coagulation; Blood Coagulation Tests; Dabigatran; Dose-Response Relationship, Drug; Female; Hemostasis; Humans; Middle Aged; Pipecolic Acids; Sulfonamides; Treatment Outcome

2013
Monitoring the direct thrombin inhibitors.
    Clinical laboratory science : journal of the American Society for Medical Technology, 2013,Winter, Volume: 26, Issue:1

    Topics: Antithrombins; Arginine; Benzimidazoles; beta-Alanine; Dabigatran; Drug Monitoring; Hirudins; Humans; Peptide Fragments; Pipecolic Acids; Recombinant Proteins; Sulfonamides

2013
A comparison of methods for estimating glomerular filtration rate for a population in Hawai'i with non-valvular atrial fibrillation.
    Hawai'i journal of medicine & public health : a journal of Asia Pacific Medicine & Public Health, 2013, Volume: 72, Issue:9 Suppl 4

    Topics: Aged, 80 and over; Anticoagulants; Arginine; Asian People; Atrial Fibrillation; Benzimidazoles; beta-Alanine; Dabigatran; Female; Glomerular Filtration Rate; Hawaii; Humans; Male; Morpholines; Pipecolic Acids; Retrospective Studies; Rivaroxaban; Sulfonamides; Thiophenes; Warfarin

2013
Dabigatran, rivaroxaban, apixaban, argatroban and fondaparinux and their effects on coagulation POC and platelet function tests.
    Clinical chemistry and laboratory medicine, 2014, Volume: 52, Issue:6

    Topics: Anticoagulants; Arginine; Artifacts; Benzimidazoles; beta-Alanine; Blood Coagulation; Dabigatran; Fondaparinux; Humans; Morpholines; Pipecolic Acids; Platelet Function Tests; Point-of-Care Systems; Polysaccharides; Pyrazoles; Pyridones; Rivaroxaban; Sulfonamides; Thiophenes; Thrombelastography; Whole Blood Coagulation Time

2014
Comparison of the aPTT with alternative tests for monitoring direct thrombin inhibitors in patient samples.
    American journal of clinical pathology, 2014, Volume: 141, Issue:5

    Topics: Antithrombins; Arginine; Benzimidazoles; beta-Alanine; Blood Coagulation; Blood Coagulation Tests; Dabigatran; Drug Monitoring; Heparin; Hirudins; Humans; Partial Thromboplastin Time; Peptide Fragments; Pipecolic Acids; Recombinant Proteins; Sulfonamides; Thrombin; Thrombin Time; Thromboplastin

2014
The paradoxical antifibrinolytic effect of dabigatran and argatroban in the presence of soluble thrombomodulin is unrelated to protein C-dependent increase of thrombin generation.
    Thrombosis research, 2014, Volume: 134, Issue:5

    Topics: Antithrombins; Arginine; Benzimidazoles; beta-Alanine; Carboxypeptidase B2; Dabigatran; Fibrinolysis; Humans; Pipecolic Acids; Protein C; Sulfonamides; Thrombin; Thrombomodulin

2014
Activated protein C resistance testing for factor V Leiden.
    American journal of hematology, 2014, Volume: 89, Issue:12

    Topics: Activated Protein C Resistance; Adult; Antithrombins; Arginine; Benzimidazoles; beta-Alanine; Biological Assay; Blood Coagulation Tests; Child; Dabigatran; Factor V; Factor Xa; False Positive Reactions; Female; Hirudins; Humans; Lupus Coagulation Inhibitor; Morpholines; Peptide Fragments; Pipecolic Acids; Pregnancy; Protein C; Recombinant Proteins; Rivaroxaban; Sulfonamides; Thiophenes; Warfarin

2014
Synthesis and Biological Evaluation of Some New 2,5-Substituted 1-Ethyl-1H-benzoimidazole Fluorinated Derivatives as Direct Thrombin Inhibitors.
    Archiv der Pharmazie, 2015, Volume: 348, Issue:5

    Topics: Antithrombins; Arginine; Benzimidazoles; Blood Coagulation; Dabigatran; Dose-Response Relationship, Drug; Drug Design; Humans; Hydrocarbons, Fluorinated; Molecular Docking Simulation; Molecular Structure; Pipecolic Acids; Structure-Activity Relationship; Sulfonamides

2015
Evaluation of anticoagulant effects of direct thrombin inhibitors, dabigatran and argatroban, based on the Lineweaver-Burk plot applied to the Clauss assay.
    Journal of clinical pathology, 2016, Volume: 69, Issue:4

    Topics: Antithrombins; Arginine; Blood Coagulation; Dabigatran; Humans; Kinetics; Pipecolic Acids; Sulfonamides

2016
Combined factor IIa and Xa inhibitor therapy for thrombosis whilst on therapeutic anticoagulant.
    Thrombosis research, 2016, Volume: 143

    Topics: Adult; Aged; Anticoagulants; Antithrombins; Arginine; Dabigatran; Factor Xa Inhibitors; Female; Heparin, Low-Molecular-Weight; Humans; Male; Middle Aged; Neoplasms; Pipecolic Acids; Pyrazoles; Pyridones; Recurrence; Rivaroxaban; Sulfonamides; Venous Thrombosis

2016
Dabigatran and Argatroban Diametrically Modulate Thrombin Exosite Function.
    PloS one, 2016, Volume: 11, Issue:6

    Topics: Allosteric Regulation; Antithrombins; Arginine; Binding Sites; Biocatalysis; Blood Coagulation; Catalytic Domain; Dabigatran; Fibrin; Fibrinogen; Humans; Pipecolic Acids; Protein Binding; Substrate Specificity; Sulfonamides; Surface Plasmon Resonance; Thrombin

2016
In vitro effects of a kaolin-coated hemostatic dressing on anticoagulated blood.
    The journal of trauma and acute care surgery, 2018, Volume: 85, Issue:3

    Topics: Adult; Anticoagulants; Antithrombins; Arginine; Bandages; Blood Coagulation; Blood Coagulation Tests; Dabigatran; Factor Xa Inhibitors; Hemostatics; Heparin; Humans; Kaolin; Pipecolic Acids; Platelet Aggregation Inhibitors; Prospective Studies; Rivaroxaban; Sulfonamides; Viscoelastic Substances; Vitamin K

2018
Dabigatran Use after Argatroban for Heparin-induced Thrombocytopenia with Thrombosis: A Case Series and Literature Review.
    Annals of vascular surgery, 2022, Volume: 80

    Topics: Aged; Anticoagulants; Antithrombins; Arginine; Dabigatran; Drug Therapy, Combination; Fatal Outcome; Female; Gastrointestinal Hemorrhage; Heparin; Humans; Male; Middle Aged; Pipecolic Acids; Platelet Count; Sulfonamides; Thrombocytopenia; Venous Thrombosis

2022
Development and validation of an analytical method for the determination of direct oral anticoagulants (DOAC) and the direct thrombin-inhibitor argatroban by HPLC-MS/MS.
    Journal of thrombosis and thrombolysis, 2022, Volume: 53, Issue:4

    Topics: Administration, Oral; Aged; Anticoagulants; Antithrombins; Arginine; Chromatography, High Pressure Liquid; Dabigatran; Humans; Pipecolic Acids; Pyridones; Rivaroxaban; Sulfonamides; Tandem Mass Spectrometry; Thrombin

2022