mci 154 has been researched along with carbachol in 2 studies
| Studies (mci 154) | Trials (mci 154) | Recent Studies (post-2010) (mci 154) | Studies (carbachol) | Trials (carbachol) | Recent Studies (post-2010) (carbachol) |
|---|---|---|---|---|---|
| 65 | 1 | 0 | 13,918 | 81 | 968 |
| Protein | Taxonomy | mci 154 (IC50) | carbachol (IC50) |
|---|---|---|---|
| Muscarinic acetylcholine receptor M2 | Homo sapiens (human) | 0.7849 | |
| Muscarinic acetylcholine receptor M4 | Homo sapiens (human) | 2.0626 | |
| Muscarinic acetylcholine receptor M1 | Rattus norvegicus (Norway rat) | 3.4134 | |
| Muscarinic acetylcholine receptor M3 | Rattus norvegicus (Norway rat) | 2.9961 | |
| Muscarinic acetylcholine receptor M4 | Rattus norvegicus (Norway rat) | 2.535 | |
| Muscarinic acetylcholine receptor M5 | Rattus norvegicus (Norway rat) | 2.9961 | |
| Muscarinic acetylcholine receptor M2 | Rattus norvegicus (Norway rat) | 2.6638 | |
| Muscarinic acetylcholine receptor M1 | Homo sapiens (human) | 4.849 | |
| Muscarinic acetylcholine receptor M3 | Homo sapiens (human) | 4.99 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gwathmey, JK; Kihara, Y; Morgan, JP; Pesaturo, J; Phillips, P; Warren, SE | 1 |
| Endoh, M; Kitada, Y; Narimatsu, A; Suzuki, R; Taira, N | 1 |
2 other study(ies) available for mci 154 and carbachol
| Article | Year |
|---|---|
Inotropic and lusitropic effects of MCI-154 (6-[4-(4- pyridyl)aminophenyl]-4,5-dihydro-3(2H)-pyridazinone) on human myocardium.
Topics: Aequorin; Carbachol; Cardiotonic Agents; Cyclic AMP; Heart; Heart Ventricles; Humans; Muscle Relaxation; Myocardial Contraction; Pyridazines | 1989 |
Does the positive inotropic action of a novel cardiotonic agent, MCI-154, involve mechanisms other than cyclic AMP?
Topics: Animals; Carbachol; Cardiotonic Agents; Cyclic AMP; Dogs; Dose-Response Relationship, Drug; Female; In Vitro Techniques; Isoproterenol; Male; Myocardial Contraction; Phosphoric Diester Hydrolases; Pindolol; Pyridazines; Reserpine; Stimulation, Chemical; Tetrodotoxin | 1987 |