mazindol has been researched along with oxidopamine in 48 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (6.25) | 18.7374 |
| 1990's | 30 (62.50) | 18.2507 |
| 2000's | 15 (31.25) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cadet, JL; Zhu, SM | 1 |
| Angulo, J; Cadet, JL; Dollison, A; Fahn, S; Kujirai, K; Zhu, SM | 1 |
| Goeders, NE | 1 |
| Cadet, JL; Kujirai, K; Przedborski, S | 1 |
| LaHoste, GJ; Marshall, JF | 2 |
| Berger, K; Cadet, JL; Przedborski, S | 1 |
| Cadet, JL; Dollison, A; Fahn, S; Gash, DM; Jackson-Lewis, V; Kostic, V; Levivier, M; Przedborski, S | 1 |
| Joyce, JN; Neal, BS | 1 |
| Joyce, JN | 2 |
| Altar, CA; Armanini, M; Bakhit, C; Dugich-Djordjevic, M | 1 |
| DeBoer, JM; Gordon, BG; Sharp, JG; Wooldridge, LD | 1 |
| Bienvenu, OJ; De Souza, EB; Goeders, NE | 1 |
| Marek, GJ; Seiden, LS; Vosmer, G | 2 |
| Cadet, JL; Fahn, S; Jackson-Lewis, V; Kostic, V; Kujirai, K; Przedborski, S | 1 |
| Angel, I; Janowsky, A; Paul, SM | 1 |
| Marshall, JF; O'Dell, SJ | 1 |
| Stoessl, AJ | 1 |
| Donaldson, D; Ferreira, M; Jackson-Lewis, V; Jiang, H; Levivier, M; Przedborski, S; Togasaki, DM | 1 |
| Fuller, RW; Hemrick-Luecke, SK; Snoddy, HD | 1 |
| Dunn-Meynell, AA; Levin, BE | 1 |
| Gnanalingham, KK; Robertson, RG | 1 |
| Hunt, SP; Jenkins, R; O'Shea, R; Thomas, KL | 1 |
| Broide, RS; Leslie, FM; Loughlin, SE; Smith, JA | 1 |
| Altar, CA; Boylan, CB; Fritsche, M; Hyman, C; Jackson, C; Jones, BE; Juhasz, M; Lindsay, RM; Wiegand, SJ | 1 |
| Hashitani, T; Kumazaki, M; Mizukawa, K; Nishino, H | 1 |
| Brotchie, JM; Crossman, AR; Henry, B | 2 |
| Han, HM; Kim, HP; Kim, SH; Kim, YC; Lee, EJ | 1 |
| Joyce, JN; Neal-Beliveau, BS; Thomas, WS | 1 |
| Araki, T; Itoyama, Y; Kato, H; Tanji, H | 1 |
| Chadha, A; Dawson, LG; Duty, S; Jenner, PG | 1 |
| Granata, R; Jenner, P; Laboyrie, P; Poewe, W; Puschban, Z; Quinn, NP; Scherfler, C; Wenning, GK | 1 |
| Donaldson, D; Levivier, M | 1 |
| Jenner, P; Kunikowska, G | 1 |
| Araki, T; Fujihara, K; Imai, Y; Itoyama, Y; Kato, H; Matsubara, M | 1 |
| Amalric, M; Baunez, C; Breysse, N; Gasparini, F; Spooren, W | 1 |
| Nielsen, KM; Soghomonian, JJ | 1 |
| Drago, J; Finkelstein, DI; Horne, MK; Krstew, EV; Lawrence, AJ; Parish, CL; Stanic, D; Zhu, WM | 1 |
| Duty, S; Johnston, T | 1 |
| Cleren, C; Costentin, J; Naudin, B | 1 |
| Cenci, MA; Lindgren, H; Lundblad, M; Picconi, B | 1 |
| Absi, el H; Bacci, JJ; Baunez, C; Kerkerian-Le Goff, L; Manrique, C; Salin, P | 1 |
| Amalric, M; Breysse, N; Kerkerian-Le Goff, L; Oueslati, A; Salin, P | 1 |
| Soghomonian, JJ | 1 |
| Soghomonian, JJ; Yamamoto, N | 1 |
48 other study(ies) available for mazindol and oxidopamine
| Article | Year |
|---|---|
The intrastriatal 6-hydroxydopamine model of hemiparkinsonism: quantitative receptor autoradiographic evidence of correlation between circling behavior and presynaptic as well as postsynaptic nigrostriatal markers in the rat.
Topics: Amphetamine; Animals; Apomorphine; Autoradiography; Biomarkers; Corpus Striatum; Immunohistochemistry; Injections; Male; Mazindol; Oxidopamine; Parkinson Disease, Secondary; Rats; Rats, Sprague-Dawley; Receptors, Dopamine; Spiperone; Stereotyped Behavior; Substantia Nigra; Synapses | 1992 |
Implantation of genetically modified mesencephalic fetal cells into the rat striatum.
Topics: Amphetamine; Animals; Autoradiography; Brain Tissue Transplantation; Cell Line; Corpus Striatum; Female; Fetal Tissue Transplantation; Genetic Vectors; Immunohistochemistry; Mazindol; Mesencephalon; Nucleic Acid Hybridization; Oxidopamine; Parkinson Disease, Secondary; Pregnancy; Protein Kinase C; Rats; Rats, Inbred Strains; Retroviridae; Stereotyped Behavior | 1992 |
Cocaine differentially affects benzodiazepine receptors in discrete regions of the rat brain: persistence and potential mechanisms mediating these effects.
Topics: Animals; Autoradiography; Brain; Cocaine; Dopamine; Dose-Response Relationship, Drug; Drug Administration Schedule; Flumazenil; Injections, Intraventricular; Kinetics; Male; Mazindol; Oxidopamine; Rats; Rats, Inbred F344; Receptors, GABA-A; Tritium | 1991 |
Bilateral modulation of [3H]neurotensin binding by unilateral intrastriatal 6-hydroxydopamine injections: evidence from a receptor autoradiographic study.
Topics: Animals; Autoradiography; Brain; Corpus Striatum; Injections; Limbic System; Male; Mazindol; Neurotensin; Oxidopamine; Rats; Rats, Inbred Strains; Receptors, Neurotensin; Receptors, Neurotransmitter; Substantia Nigra | 1991 |
Chronic eticlopride and dopamine denervation induce equal nonadditive increases in striatal D2 receptor density: autoradiographic evidence against the dual mechanism hypothesis.
Topics: Analysis of Variance; Animals; Apomorphine; Autoradiography; Corpus Striatum; Denervation; Dopamine; Dopamine Agents; Ergolines; Hydroxydopamines; Male; Mazindol; Nucleus Accumbens; Oxidopamine; Quinpirole; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Dopamine D2; Salicylamides; Tritium | 1991 |
Retrograde degeneration of nigrostriatal neurons induced by intrastriatal 6-hydroxydopamine injection in rats.
Topics: Animals; Basal Ganglia; Benzazepines; Caudate Nucleus; Hydroxydopamines; Male; Mazindol; Neurons; Oxidopamine; Putamen; Rats; Receptors, Dopamine; Receptors, Dopamine D1; Receptors, Dopamine D2; Substantia Nigra | 1991 |
Sham transplantation protects against 6-hydroxydopamine-induced dopaminergic toxicity in rats: behavioral and morphological evidence.
Topics: Analysis of Variance; Animals; Autoradiography; Benzazepines; Brain Tissue Transplantation; Corpus Striatum; Dopamine; Female; Fetal Tissue Transplantation; Hydroxydopamines; Liver Transplantation; Mazindol; Oxidopamine; Rats; Receptors, Dopamine; Receptors, Dopamine D1; Stereotyped Behavior; Transplantation, Heterotopic; Tritium | 1991 |
Dopamine D1 receptor behavioral responsitivity following selective lesions of the striatal patch compartment during development.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Aging; Analysis of Variance; Animals; Animals, Newborn; Apomorphine; Autoradiography; Corpus Striatum; Haloperidol; Hydroxydopamines; Levodopa; Mazindol; Motor Activity; Neurotoxins; Oxidopamine; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Dopamine D1; Stereotyped Behavior; Tritium | 1991 |
Differential response of striatal dopamine and muscarinic cholinergic receptor subtypes to the loss of dopamine. I. Effects of intranigral or intracerebroventricular 6-hydroxydopamine lesions of the mesostriatal dopamine system.
Topics: Animals; Autoradiography; Corpus Striatum; Dopamine; Hemicholinium 3; Injections, Intraventricular; Male; Mazindol; Oxidopamine; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Dopamine D2; Receptors, Muscarinic; Substantia Nigra | 1991 |
Differential response of striatal dopamine and muscarinic cholinergic receptor subtypes to the loss of dopamine. II. Effects of 6-hydroxydopamine or colchicine microinjections into the VTA or reserpine treatment.
Topics: Animals; Autoradiography; Caudate Nucleus; Colchicine; Corpus Striatum; Dopamine; Male; Mazindol; Microinjections; Oxidopamine; Putamen; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Dopamine D2; Receptors, Muscarinic; Reserpine; Tegmentum Mesencephali | 1991 |
Medial-to-lateral gradient of neostriatal NGF receptors: relationship to cholinergic neurons and NGF-like immunoreactivity.
Topics: Animals; Binding, Competitive; Caudate Nucleus; Choline O-Acetyltransferase; Corpus Striatum; Dopamine; Dopamine Antagonists; Hydroxydopamines; Kinetics; Male; Mazindol; Nerve Growth Factors; Neurons; Oxidopamine; Putamen; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, GABA-A; Receptors, Nerve Growth Factor; Recombinant Proteins | 1991 |
Effect of 6-hydroxydopamine on murine hematopoietic stem cells: enhanced cytotoxicity on megakaryocyte colony forming units.
Topics: Animals; Cell Survival; Colony-Forming Units Assay; Granulocytes; Hematopoietic Stem Cells; Hydroxydopamines; Macrophages; Mazindol; Megakaryocytes; Mice; Oxidopamine; Spleen; Tumor Cells, Cultured | 1991 |
Chronic cocaine administration alters corticotropin-releasing factor receptors in the rat brain.
Topics: Animals; Autoradiography; Brain; Cerebral Ventricles; Cocaine; Corticotropin-Releasing Hormone; Desipramine; Hydroxydopamines; Male; Mazindol; Organ Specificity; Oxidopamine; Rats; Rats, Inbred F344; Receptors, Corticotropin-Releasing Hormone; Receptors, Neurotransmitter; Reference Values; Substance-Related Disorders; Tritium | 1990 |
Dopamine uptake inhibitors block long-term neurotoxic effects of methamphetamine upon dopaminergic neurons.
Topics: Animals; Corpus Striatum; Dopamine; Hydroxydopamines; Indoles; Male; Mazindol; Methamphetamine; Nalidixic Acid; Naphthyridines; Neurotoxins; Neurotransmitter Uptake Inhibitors; Oxidopamine; Rats; Rats, Inbred Strains; Serotonin | 1990 |
The effects of monoamine uptake inhibitors and methamphetamine on neostriatal 6-hydroxydopamine (6-OHDA) formation, short-term monoamine depletions and locomotor activity in the rat.
Topics: Animals; Brain; Dopamine; Hydroxydopamines; Male; Mazindol; Methamphetamine; Motor Activity; Nalidixic Acid; Naphthyridines; Neurotransmitter Uptake Inhibitors; Oxidopamine; Rats; Rats, Inbred Strains; Serotonin | 1990 |
Autoradiography of dopamine receptors and dopamine uptake sites in the spontaneously hypertensive rat.
Topics: Animals; Autoradiography; Benzazepines; Brain; Dopamine; Hydroxydopamines; Hypertension; Mazindol; Oxidopamine; Radioligand Assay; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Dopamine D1; Receptors, Dopamine D2; Spiperone; Tritium | 1990 |
The effects of serotonergic and dopaminergic lesions on sodium-sensitive [3H]mazindol binding in rat hypothalamus and corpus striatum.
Topics: 5,7-Dihydroxytryptamine; Animals; Corpus Striatum; Dopamine; Hydroxydopamines; Hypothalamus; Indoles; Injections, Intraventricular; Mazindol; Oxidopamine; Rats; Serotonin; Sodium; Synaptosomes | 1989 |
Non-additivity of D2 receptor proliferation induced by dopamine denervation and chronic selective antagonist administration: evidence from quantitative autoradiography indicates a single mechanism of action.
Topics: Animals; Corpus Striatum; Dopamine; Dopamine Antagonists; Hydroxydopamines; Male; Mazindol; Metoclopramide; Oxidopamine; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Dopamine D2 | 1989 |
Transport of [3H]mazindol binding sites in mesostriatal dopamine axons.
Topics: Animals; Axons; Corpus Striatum; Dopamine; Hydroxydopamines; Indoles; Male; Mazindol; Oxidopamine; Rats; Rats, Inbred Strains; Receptors, Dopamine | 1988 |
Localization of striatal and nigral tachykinin receptors in the rat.
Topics: Animals; Autoradiography; Corpus Striatum; Male; Mazindol; Medial Forebrain Bundle; Oxidopamine; Peptide Fragments; Quinolinic Acid; Rats; Rats, Sprague-Dawley; Receptors, Tachykinin; Substance P; Substantia Nigra; Tissue Distribution | 1994 |
Dose-dependent lesions of the dopaminergic nigrostriatal pathway induced by intrastriatal injection of 6-hydroxydopamine.
Topics: Animals; Apomorphine; Autoradiography; Behavior, Animal; Disease Models, Animal; Dose-Response Relationship, Drug; Male; Mazindol; Neural Pathways; Oxidopamine; Parkinson Disease; Rats; Rats, Sprague-Dawley; Substantia Nigra; Time Factors | 1995 |
Fluoxetine at anorectic doses does not have properties of a dopamine uptake inhibitor.
Topics: 3,4-Dihydroxyphenylacetic Acid; Amphetamine; Animals; Appetite Depressants; Brain Chemistry; Dopamine; Dopamine Uptake Inhibitors; Fluoxetine; Homovanillic Acid; Injections, Intraventricular; Male; Mazindol; Neostriatum; Oxidopamine; Rats; Rats, Sprague-Dawley | 1994 |
Selective sprouting of injured dopaminergic neurons induced by embryonic brain grafts.
Topics: Animals; Autoradiography; Brain Tissue Transplantation; Carrier Proteins; Cerebral Cortex; Desipramine; Dopamine; Dopamine beta-Hydroxylase; Dopamine Plasma Membrane Transport Proteins; Fetal Tissue Transplantation; Immunohistochemistry; Male; Mazindol; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Fibers; Nerve Tissue Proteins; Neurons; Norepinephrine Plasma Membrane Transport Proteins; Oxidopamine; Prosencephalon; Rats; Rats, Sprague-Dawley; Symporters; Tritium; Tyrosine 3-Monooxygenase | 1993 |
The effects of chronic continuous versus intermittent levodopa treatments on striatal and extrastriatal D1 and D2 dopamine receptors and dopamine uptake sites in the 6-hydroxydopamine lesioned rat--an autoradiographic study.
Topics: Animals; Apomorphine; Autoradiography; Behavior, Animal; Benzazepines; Dopamine; Levodopa; Male; Mazindol; Medial Forebrain Bundle; Neostriatum; Oxidopamine; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, Dopamine D2; Stereotyped Behavior; Sulpiride | 1994 |
c-jun expression in substantia nigra neurons following striatal 6-hydroxydopamine lesions in the rat.
Topics: Animals; Autoradiography; Corpus Striatum; Female; Gene Expression; Genes, jun; Ibotenic Acid; Immunohistochemistry; In Situ Hybridization; Mazindol; Neurons; Oxidopamine; Proto-Oncogene Proteins c-jun; Rats; Rats, Sprague-Dawley; Receptors, Dopamine; RNA, Messenger; Substantia Nigra; Tyrosine 3-Monooxygenase | 1993 |
Long-term changes in striatal opioid systems after 6-hydroxydopamine lesion of rat substantia nigra.
Topics: Animals; Corpus Striatum; Dopamine; Down-Regulation; Endorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine-2-Alanine; Enkephalins; Gene Expression Regulation; Male; Mazindol; Oxidopamine; Protein Precursors; Rats; Rats, Sprague-Dawley; Receptors, Dopamine; Receptors, Opioid; RNA, Messenger; Substantia Nigra; Time Factors | 1993 |
A continuous striatal infusion of 6-hydroxydopamine produces a terminal axotomy and delayed behavioral effects.
Topics: Animals; Autoradiography; Axons; Behavior, Animal; Binding, Competitive; Biogenic Monoamines; Cell Line; Choline; Corpus Striatum; Denervation; gamma-Aminobutyric Acid; Glutamic Acid; Immunohistochemistry; Male; Mazindol; Oxidopamine; Rats; Rats, Sprague-Dawley; Stereotyped Behavior; Tyrosine 3-Monooxygenase | 1996 |
Dopamine metabolism in the striatum of hemiparkinsonian model rats with dopaminergic grafts.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Autoradiography; Brain Tissue Transplantation; Carrier Proteins; Corpus Striatum; Dopamine; Dopamine Plasma Membrane Transport Proteins; Female; Fetal Tissue Transplantation; Functional Laterality; Haloperidol; Homovanillic Acid; Kinetics; Levodopa; Mazindol; Membrane Glycoproteins; Membrane Transport Proteins; Mesencephalon; Methamphetamine; Microdialysis; Motor Activity; Nerve Tissue Proteins; Oxidopamine; Parkinson Disease, Secondary; Rats; Rats, Wistar; Rotation; Tritium; Tyrosine 3-Monooxygenase | 1998 |
Characterization of enhanced behavioral responses to L-DOPA following repeated administration in the 6-hydroxydopamine-lesioned rat model of Parkinson's disease.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Antiparkinson Agents; Behavior, Animal; Bromocriptine; Clonidine; Disease Models, Animal; Dopamine; Dopamine Uptake Inhibitors; Dyskinesia, Drug-Induced; Levodopa; Lisuride; Locomotion; Male; Mazindol; Methoxydimethyltryptamines; Oxidopamine; Parkinson Disease, Secondary; Prosencephalon; Rats; Rats, Sprague-Dawley; Sympatholytics; Tritium; Yohimbine | 1998 |
Cell death and cytoskeletal alterations in cultured hepatic fat-storing cells induced by 6-hydroxydopamine.
Topics: Actins; Adipocytes; Animals; Antioxidants; Cell Death; Cells, Cultured; Cytoskeleton; Dopamine Uptake Inhibitors; Glutathione; Liver; Male; Mazindol; Oxidative Stress; Oxidopamine; Propyl Gallate; Rats; Rats, Wistar; Receptors, Dopamine | 1998 |
There is a limited critical period for dopamine's effects on D1 receptor expression in the developing rat neostriatum.
Topics: Aging; Animals; Animals, Newborn; Benzazepines; Carrier Proteins; Corpus Striatum; Dopamine; Dopamine Antagonists; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Mazindol; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Oxidopamine; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, Dopamine D2; Spiperone | 1998 |
Sequential changes of dopaminergic receptors in the rat brain after 6-hydroxydopamine lesions of the medial forebrain bundle.
Topics: Adrenergic Agents; Animals; Autoradiography; Benzamides; Benzazepines; Brain Diseases; Dopamine; Dopamine Antagonists; Dopamine Uptake Inhibitors; Male; Mazindol; Medial Forebrain Bundle; Oxidopamine; Rats; Rats, Wistar; Receptors, Dopamine; Receptors, Dopamine D1; Receptors, Dopamine D2; Time Factors | 1998 |
Effect of repeated L-DOPA, bromocriptine, or lisuride administration on preproenkephalin-A and preproenkephalin-B mRNA levels in the striatum of the 6-hydroxydopamine-lesioned rat.
Topics: Animals; Autoradiography; Behavior, Animal; Bromocriptine; Dopamine Agents; Dopamine Agonists; Dopamine Uptake Inhibitors; Enkephalins; In Situ Hybridization; Levodopa; Lisuride; Male; Mazindol; Medial Forebrain Bundle; Neostriatum; Oligonucleotide Probes; Oxidopamine; Parkinson Disease, Secondary; Protein Precursors; Radioligand Assay; Rats; Rats, Sprague-Dawley; RNA, Messenger | 1999 |
Effect of unilateral 6-hydroxydopamine lesions of the nigrostriatal pathway on GABA(A) receptor subunit gene expression in the rodent basal ganglia and thalamus.
Topics: Animals; Autoradiography; Basal Ganglia; Corpus Striatum; Gene Expression; Male; Mazindol; Neural Pathways; Oxidopamine; Protein Isoforms; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; RNA, Messenger; Substantia Nigra; Thalamus; Tissue Distribution | 2000 |
Autoradiographic study of striatal dopamine re-uptake sites and dopamine D1 and D2 receptors in a 6-hydroxydopamine and quinolinic acid double-lesion rat model of striatonigral degeneration (multiple system atrophy) and effects of embryonic ventral mesenc
Topics: Amphetamine; Animals; Apomorphine; Atrophy; Autoradiography; Behavior, Animal; Brain Tissue Transplantation; Corpus Striatum; Dopamine; Dopamine Agonists; Dopamine Uptake Inhibitors; Fetal Tissue Transplantation; Male; Mazindol; Nerve Degeneration; Neurons; Oxidopamine; Quinolinic Acid; Rats; Rats, Wistar; Receptors, Dopamine D1; Receptors, Dopamine D2; Rotation; Substantia Nigra; Sympatholytics; Tritium | 2000 |
Metabolic changes after injection of quinolinic acid or 6-hydroxydopamine in the rat striatum: a time-course study using cytochrome oxidase and glycogene phosphorylase a histochemistry.
Topics: Animals; Autoradiography; Benzazepines; Biomarkers; Corpus Striatum; Disease Models, Animal; Dopamine Antagonists; Dopamine Uptake Inhibitors; Electron Transport Complex IV; Glycogen; Huntington Disease; Male; Mazindol; Microinjections; Nerve Degeneration; Oxidopamine; Parkinson Disease; Phosphorylase a; Quinolinic Acid; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Dopamine; Sympatholytics; Tritium | 2000 |
6-Hydroxydopamine-lesioning of the nigrostriatal pathway in rats alters basal ganglia mRNA for copper, zinc- and manganese-superoxide dismutase, but not glutathione peroxidase.
Topics: Adrenergic Uptake Inhibitors; Animals; Basal Ganglia; Behavior, Animal; DNA Probes; Dopamine; Female; Glutathione Peroxidase; In Situ Hybridization; Male; Mazindol; Neostriatum; Neural Pathways; Oxidopamine; Rats; RNA, Messenger; Substantia Nigra; Superoxide Dismutase; Sympathectomy, Chemical; Sympatholytics | 2001 |
Gamma-aminobutyric acidA and benzodiazepine receptor alterations in the rat brain after unilateral 6-hydroxydopamine lesions of the medial forebrain bundle.
Topics: Animals; Dopamine; Dopamine Uptake Inhibitors; Down-Regulation; Flunitrazepam; GABA Agonists; GABA Modulators; Male; Mazindol; Muscimol; Neostriatum; Neural Pathways; Oxidopamine; Parkinson Disease; Radioligand Assay; Rats; Rats, Wistar; Receptors, Dopamine; Receptors, GABA-A; Substantia Nigra; Sympatholytics; Tritium; Up-Regulation | 2002 |
Chronic but not acute treatment with a metabotropic glutamate 5 receptor antagonist reverses the akinetic deficits in a rat model of parkinsonism.
Topics: Animals; Behavior, Animal; Catalepsy; Corpus Striatum; Excitatory Amino Acid Antagonists; Kinetics; Male; Mazindol; Motor Activity; Oxidopamine; Parkinsonian Disorders; Pyridines; Rats; Rats, Sprague-Dawley; Rats, Wistar; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Time Factors | 2002 |
Dual effects of intermittent or continuous L-DOPA administration on gene expression in the globus pallidus and subthalamic nucleus of adult rats with a unilateral 6-OHDA lesion.
Topics: Animals; Autoradiography; Behavior, Animal; Dopamine; Dopamine Agents; Dopamine Uptake Inhibitors; Electron Transport Complex IV; Gene Expression Regulation; Gene Expression Regulation, Enzymologic; Globus Pallidus; Glutamate Decarboxylase; In Situ Hybridization; Isoenzymes; Levodopa; Male; Mazindol; Neurons; Oxidopamine; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; RNA, Messenger; Substantia Nigra; Subthalamic Nucleus | 2003 |
Changes in function and ultrastructure of striatal dopaminergic terminals that regenerate following partial lesions of the SNpc.
Topics: Amphetamine; Animals; Behavior, Animal; Binding, Competitive; Biological Transport; Cell Count; Corpus Striatum; Dopamine; Dopamine Agonists; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Electrochemistry; Male; Mazindol; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Regeneration; Nerve Tissue Proteins; Oxidopamine; Presynaptic Terminals; Quinpirole; Rats; Rats, Wistar; Substantia Nigra; Synaptosomes | 2003 |
Changes in GABA(B) receptor mRNA expression in the rodent basal ganglia and thalamus following lesion of the nigrostriatal pathway.
Topics: Animals; Autoradiography; Basal Ganglia; Densitometry; Dopamine Uptake Inhibitors; Gene Expression; Male; Mazindol; Neural Pathways; Oligonucleotide Probes; Oxidopamine; Rats; Rats, Sprague-Dawley; Receptors, GABA-B; RNA, Messenger; Substantia Nigra; Thalamus; Tritium | 2003 |
Apparent opposite effects of tetrabenazine and reserpine on the toxic effects of 1-methyl-4-phenylpyridinium or 6-hydroxydopamine on nigro-striatal dopaminergic neurons.
Topics: 1-Methyl-4-phenylpyridinium; Adrenergic Uptake Inhibitors; Analysis of Variance; Animals; Binding Sites; Body Temperature; Dopamine; Drug Administration Routes; Drug Interactions; Hypothalamus; Hypothermia; Male; Mazindol; Membrane Glycoproteins; Membrane Transport Proteins; Mice; Neostriatum; Neurons; Neuropeptides; Neurotoxins; Oxidopamine; Reserpine; Substantia Nigra; Tetrabenazine; Tritium; Vesicular Biogenic Amine Transport Proteins; Vesicular Monoamine Transport Proteins | 2003 |
A model of L-DOPA-induced dyskinesia in 6-hydroxydopamine lesioned mice: relation to motor and cellular parameters of nigrostriatal function.
Topics: Animals; Corpus Striatum; Disease Models, Animal; Dyskinesia, Drug-Induced; Levodopa; Male; Mazindol; Mice; Mice, Inbred C57BL; Motor Skills; Oxidopamine; Protein Binding; Substantia Nigra | 2004 |
Differential effects of prolonged high frequency stimulation and of excitotoxic lesion of the subthalamic nucleus on dopamine denervation-induced cellular defects in the rat striatum and globus pallidus.
Topics: Animals; Corpus Striatum; Denervation; Dopamine; Electric Stimulation; Globus Pallidus; Male; Mazindol; Oxidopamine; Protein Binding; Rats; Rats, Wistar; RNA, Messenger; Subthalamic Nucleus | 2004 |
Dysfunction of the cortico-basal ganglia-cortical loop in a rat model of early parkinsonism is reversed by metabotropic glutamate receptor 5 antagonism.
Topics: Animals; Basal Ganglia; Cerebral Cortex; Denervation; Dopamine Uptake Inhibitors; Electron Transport Complex IV; Enkephalins; Excitatory Amino Acid Antagonists; In Situ Hybridization; Male; Mazindol; Neostriatum; Nerve Net; Neurons; Oxidopamine; Parkinson Disease, Secondary; Protein Precursors; Rats; Rats, Wistar; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; RNA, Messenger; Sympatholytics; Tachykinins; Thalamus | 2005 |
L-DOPA-induced dyskinesia in adult rats with a unilateral 6-OHDA lesion of dopamine neurons is paralleled by increased c-fos gene expression in the subthalamic nucleus.
Topics: Animals; Autoradiography; Behavior, Animal; Dopamine; Dopamine Agents; Dopamine Uptake Inhibitors; Dyskinesias; Functional Laterality; Gene Expression; Immunohistochemistry; In Situ Hybridization; Levodopa; Male; Mazindol; Neurons; Oxidopamine; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Substantia Nigra; Subthalamic Nucleus; Time Factors; Tritium | 2006 |
Time-course of SKF-81297-induced increase in glutamic acid decarboxylase 65 and 67 mRNA levels in striatonigral neurons and decrease in GABA(A) receptor alpha1 subunit mRNA levels in the substantia nigra, pars reticulata, in adult rats with a unilateral 6
Topics: Adrenergic Uptake Inhibitors; Animals; Autoradiography; Benzazepines; Dopamine Agonists; Glutamate Decarboxylase; Immunohistochemistry; In Situ Hybridization; Male; Mazindol; Neostriatum; Neurons; Oxidopamine; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; RNA, Messenger; Stimulation, Chemical; Substantia Nigra; Sympathectomy, Chemical; Sympatholytics | 2008 |