mazindol and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine

mazindol has been researched along with 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in 34 studies

Research

Studies (34)

Timeframe	Studies, this research(%)	All Research%
pre-1990	12 (35.29)	18.7374
1990's	17 (50.00)	18.2507
2000's	5 (14.71)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Duchemin, AM; Gudehithlu, KP; Hadjiconstantinou, M; Neff, NH	1
Alexander, GM; Brainard, L; Gordon, SW; Grothusen, JR; Schwartzman, RJ	1
Cadet, JL; Fahn, S; Jackson-Lewis, V; Kostic, V; Levivier, M; Popilskis, S; Przedborski, S	1
Crossman, AR; Graham, WC; Hill, DR; Sambrook, MA; Woodruff, GN	1
Danias, P; Mytilineou, C; Nicklas, WJ; Ofori, S; Shen, J	1
Goldstein, M; Jonsson, G; Luthman, J; Sundström, E	1
Barker, JL; di Porzio, U; Kopin, IJ; Schinelli, S; Zuddas, A	1
Debler, EA; Hashim, A; Lajtha, A; Sershen, H	1
Delanney, LE; Forno, LS; Irwin, I; Langston, JW; Peroutka, SJ; Ricaurte, GA	1
Donnan, GA; Figdor, R; Kaczmarczyk, SJ; Mendelsohn, FA; Rowe, PJ	1
Hashim, A; Lajtha, A; Mason, MF; Reith, ME; Sershen, H	1
Heikkila, RE; Saari, WS; Youngster, SK	1
Donnan, GA; Kaczmarczyk, SJ; Kalnins, RM; McKenzie, JS; Mendelsohn, FA; Rowe, PJ	1
Carlsson, A; Pileblad, E	1
Hashim, A; Lajtha, A; Reith, ME; Sershen, H	1
Brooks, JD; DeLanney, LE; Irwin, I; Langston, JW; Ricaurte, GA	1
Gnanalingham, KK; Hunter, AJ; Jenner, P; Marsden, CD; Milkowski, NA; Smith, LA	1
Jenner, P; Jolkkonen, J; Marsden, CD	1
Frohna, PA; Joyce, JN; Rothblat, DS; Schneider, JS	1
Chan, P; Di Monte, DA; Langston, JW	1
Audet, G; Parent, A; Pedneault, S; Soghomonian, JJ	1
Gnanalingham, KK; Hunter, AJ; Jenner, P; Marsden, CD; Smith, LA	1
Chan, P; DeLanney, LE; Di Monte, DA; Irwin, I; Langston, JW	1
DeLanney, LE; Graybiel, AM; Irwin, I; Langston, JW; Moratalla, R; Quinn, B	1
Hattori, T; Sugimoto, T; Takada, M	1
Bennett, JP; Jung, AB; Smith, TS; Trimmer, PA	1
Ali, SF; Itzhak, Y; Martin, JL; Norenberg, MD	1
Araki, T; Fujihara, K; Itoyama, Y; Nagasawa, H; Tanji, H	1
Pope-Coleman, A; Schneider, JS; Tinker, JP	1
Costa, S; Jenner, P; Marsden, CD; Pearce, RK	1
Schneider, JS; Wade, TV	1
Chen, JF; Schwarzschild, MA; Xu, K; Xu, YH	1
Jenner, P; Kunikowska, G	1
Baudry, M; Fonck, C	1

Reviews

1 review(s) available for mazindol and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine

Article	Year
Unilateral MPTP-induced parkinsonism in monkeys. A quantitative autoradiographic study of dopamine D1 and D2 receptors and re-uptake sites. Neuro-Chirurgie, 1991, Volume: 37, Issue:6 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Autoradiography; Brain Chemistry; Carotid Arteries; Corpus Striatum; Disease Models, Animal; Female; Macaca mulatta; Male; Mazindol; Parkinson Disease, Secondary; Receptors, Dopamine; Substantia Nigra	1991

Article

Year

Unilateral MPTP-induced parkinsonism in monkeys. A quantitative autoradiographic study of dopamine D1 and D2 receptors and re-uptake sites.

Neuro-Chirurgie, 1991, Volume: 37, Issue:6

Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Autoradiography; Brain Chemistry; Carotid Arteries; Corpus Striatum; Disease Models, Animal; Female; Macaca mulatta; Male; Mazindol; Parkinson Disease, Secondary; Receptors, Dopamine; Substantia Nigra

1991

Other Studies

33 other study(ies) available for mazindol and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine

Article	Year
c-fos mRNA in mouse brain after MPTP treatment. Neurochemistry international, 1992, Volume: 20, Issue:3 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Blotting, Northern; Brain; Dose-Response Relationship, Drug; Genes, fos; Kinetics; Male; Mazindol; Mice; Neurotoxins; Organ Specificity; Pargyline; Reference Values; RNA; RNA, Messenger; Selegiline; Time Factors	1992
Changes in brain catecholamines and dopamine uptake sites at different stages of MPTP parkinsonism in monkeys. Brain research, 1992, Aug-21, Volume: 588, Issue:2 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Brain; Brain Chemistry; Catecholamines; Dopamine; Dopamine Agents; Levodopa; Macaca fascicularis; Male; Mazindol; Parkinson Disease, Secondary; Receptors, Dopamine	1992
Reduction of [125I]Bolton Hunter CCK8 and [3H]MK-329 (devazepide) binding to CCK receptors in the substantia nigra/VTA complex and its forebrain projection areas following MPTP-induced hemi-parkinsonism in the monkey. Neuroscience letters, 1991, Sep-30, Volume: 131, Issue:1 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Autoradiography; Benzodiazepinones; Cholecystokinin; Devazepide; Indicators and Reagents; Iodine Radioisotopes; Macaca fascicularis; Mazindol; Parkinson Disease, Secondary; Prosencephalon; Receptors, Cholecystokinin; Sincalide; Substantia Nigra; Succinimides; Sulpiride; Tegmentum Mesencephali; Tritium	1991
Mesencephalic dopamine neurons become less sensitive to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine toxicity during development in vitro. Journal of neurochemistry, 1989, Volume: 53, Issue:4 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 1-Methyl-4-phenylpyridinium; Animals; Cells, Cultured; Designer Drugs; Dopamine; Embryo, Mammalian; Isoenzymes; Kinetics; Mazindol; Mesencephalon; Monoamine Oxidase; Neurons; Neurotoxins; Pyridines; Pyridinium Compounds; Rats; Rats, Inbred Strains; Reserpine; Rotenone; Time Factors	1989
Time course of MPTP-induced degeneration of the nigrostriatal dopamine system in C57 BL/6 mice. Brain research bulletin, 1988, Volume: 21, Issue:2 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Dopamine; Hydroxydopamines; Male; Mazindol; Mice; Mice, Inbred C57BL; Nerve Degeneration; Pyridines; Substantia Nigra; Tyrosine 3-Monooxygenase	1988
1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine metabolism and 1-methyl-4-phenylpyridinium uptake in dissociated cell cultures from the embryonic mesencephalon. Journal of neurochemistry, 1988, Volume: 50, Issue:6 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 1-Methyl-4-phenylpyridinium; Animals; Astrocytes; Cells, Cultured; Dopamine; Kinetics; Mazindol; Mesencephalon; Mice; Neurons; Pyridines; Pyridinium Compounds; Tetrodotoxin; Veratridine	1988
Ascorbic acid and striatal transport of [3H] 1-methyl-4-phenylpyridine (MPP+) and [3H] dopamine. Life sciences, 1988, Volume: 42, Issue:25 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Ascorbic Acid; Biological Transport; Cocaine; Corpus Striatum; Dopamine; Kinetics; Mazindol; Mice; Nicotine; Piperazines; Pyridines; Synaptosomes	1988
Fate of nigrostriatal neurons in young mature mice given 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine: a neurochemical and morphological reassessment. Brain research, 1986, Jun-18, Volume: 376, Issue:1 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Corpus Striatum; Dopamine; Male; Mazindol; Mice; Mice, Inbred C57BL; Nerve Degeneration; Nerve Endings; Neurochemistry; Neurons; Pyridines; Substantia Nigra; Tritium	1986
The effects of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine on presynaptic dopamine uptake sites in the mouse striatum. Journal of the neurological sciences, 1986, Volume: 74, Issue:1 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Corpus Striatum; Dopamine; Kinetics; Mazindol; Mice; Mice, Inbred C57BL; Pyridines	1986
Effect of nicotine and amphetamine on the neurotoxicity of N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) in mice. Neuropharmacology, 1986, Volume: 25, Issue:11 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Cell Membrane; Corpus Striatum; Dextroamphetamine; Dopamine; Drug Synergism; Female; Mazindol; Mice; Mice, Inbred BALB C; Nicotine; Pyridines	1986
1-Methyl-4-cyclohexyl-1,2,3,6-tetrahydropyridine (MCTP): an alicyclic MPTP-like neurotoxin. Neuroscience letters, 1987, Aug-18, Volume: 79, Issue:1-2 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Caudate Nucleus; Dopamine; Indans; Male; Mazindol; Mice; Mice, Inbred BALB C; Putamen; Pyridines; Synaptosomes	1987
Regional and temporal effects of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine on dopamine uptake sites in mouse brain. Journal of the neurological sciences, 1987, Volume: 81, Issue:2-3 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Autoradiography; Brain; Dopamine; Injections, Intraperitoneal; Mazindol; Mice; Mice, Inbred C57BL; Pyridines; Receptors, Dopamine; Time Factors	1987
Catecholamine-uptake inhibitors prevent the neurotoxicity of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) in mouse brain. Neuropharmacology, 1985, Volume: 24, Issue:7 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Brain; Catecholamines; Male; Maprotiline; Mazindol; Mice; Nervous System Diseases; Pyridines	1985
Protection against 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine neurotoxicity by the antioxidant ascorbic acid. Neuropharmacology, 1985, Volume: 24, Issue:12 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Ascorbic Acid; Corpus Striatum; Mazindol; Mice; Mice, Inbred BALB C; Nervous System; Pyridines; Synaptosomes	1985
Dopamine uptake blockers protect against the dopamine depleting effect of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) in the mouse striatum. Neuroscience letters, 1985, Sep-06, Volume: 59, Issue:3 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Benztropine; Bupropion; Corpus Striatum; Dopamine; Male; Mazindol; Mice; Mice, Inbred C57BL; Nalidixic Acid; Naphthyridines; Parasympatholytics; Propiophenones; Pyridines; Receptors, Dopamine	1985
Short- and long-term changes in striatal and extrastriatal dopamine uptake sites in the MPTP-treated common marmoset. European journal of pharmacology, 1995, Apr-24, Volume: 277, Issue:2-3 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Analysis of Variance; Animals; Autoradiography; Callithrix; Caudate Nucleus; Corpus Striatum; Disease Models, Animal; Dopamine; Female; Frontal Lobe; Globus Pallidus; Male; Mazindol; Nucleus Accumbens; Parkinson Disease; Putamen; Substantia Nigra; Tissue Distribution; Ventral Tegmental Area	1995
L-DOPA reverses altered gene expression of substance P but not enkephalin in the caudate-putamen of common marmosets treated with MPTP. Brain research. Molecular brain research, 1995, Volume: 32, Issue:2 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Autoradiography; Callithrix; Caudate Nucleus; Enkephalins; Female; Gene Expression; In Situ Hybridization; Levodopa; Male; Mazindol; Motor Activity; Nucleus Accumbens; Putamen; RNA, Messenger; Substance P	1995
Alterations in dopamine uptake sites and D1 and D2 receptors in cats symptomatic for and recovered from experimental parkinsonism. Synapse (New York, N.Y.), 1995, Volume: 19, Issue:1 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Autoradiography; Cats; Corpus Striatum; Mazindol; Parkinson Disease, Secondary; Receptors, Dopamine D1; Receptors, Dopamine D2; Substantia Nigra	1995
Effects of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) on levels of glutamate and aspartate in the mouse brain. Brain research, 1994, Jun-06, Volume: 647, Issue:2 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Aspartic Acid; Brain Chemistry; Deoxyglucose; Energy Metabolism; Glutamic Acid; Male; Mazindol; Mice; Mice, Inbred C57BL; Receptors, N-Methyl-D-Aspartate; Selegiline	1994
Increased glutamate decarboxylase mRNA levels in the striatum and pallidum of MPTP-treated primates. The Journal of neuroscience : the official journal of the Society for Neuroscience, 1994, Volume: 14, Issue:10 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Autoradiography; Axons; Corpus Striatum; Gene Expression Regulation; Globus Pallidus; Glutamate Decarboxylase; Mazindol; Parkinson Disease, Secondary; Putamen; Radiography; RNA, Messenger; Saimiri	1994
Alterations in striatal and extrastriatal D-1 and D-2 dopamine receptors in the MPTP-treated common marmoset: an autoradiographic study. Synapse (New York, N.Y.), 1993, Volume: 14, Issue:2 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Autoradiography; Benzazepines; Brain; Callithrix; Corpus Striatum; Female; Male; Mazindol; Parkinson Disease, Secondary; Receptors, Dopamine D1; Receptors, Dopamine D2; Spiperone; Tissue Distribution	1993
2-deoxyglucose enhances 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced ATP loss in the mouse brain. Journal of neurochemistry, 1993, Volume: 61, Issue:2 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Adenosine Triphosphate; Animals; Brain; Cerebellar Cortex; Deoxyglucose; Drug Interactions; Male; Mazindol; Mice; Mice, Inbred C57BL; Pyridinium Compounds	1993
Early-stage loss of dopamine uptake-site binding in MPTP-treated monkeys. Advances in neurology, 1993, Volume: 60 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Autoradiography; Brain Mapping; Caudate Nucleus; Corpus Striatum; Dopamine; Dose-Response Relationship, Drug; Injections, Subcutaneous; Mazindol; Neural Pathways; Parkinson Disease, Secondary; Putamen; Receptors, Dopamine; Saimiri; Substantia Nigra	1993
MPTP neurotoxicity to cerebellar Purkinje cells in mice. Neuroscience letters, 1993, Feb-05, Volume: 150, Issue:1 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Benztropine; Dose-Response Relationship, Drug; Male; Mazindol; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; MPTP Poisoning; Neurotoxins; Pargyline; Purkinje Cells; Selegiline	1993
Dopamine neurons from transgenic mice with a knockout of the p53 gene resist MPTP neurotoxicity. Neurodegeneration : a journal for neurodegenerative disorders, neuroprotection, and neuroregeneration, 1996, Volume: 5, Issue:3 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Cell Count; Corpus Striatum; Dopamine; Genes, p53; Immunohistochemistry; Mazindol; Mice; Mice, Knockout; Mice, Transgenic; Neurons; Neurotoxins; Substantia Nigra; Tyrosine 3-Monooxygenase	1996
Depletion of striatal dopamine transporter does not affect psychostimulant-induced locomotor activity. Neuroreport, 1997, Oct-20, Volume: 8, Issue:15 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Carrier Proteins; Central Nervous System Stimulants; Dopamine Agents; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Kinetics; Male; Mazindol; Membrane Glycoproteins; Membrane Transport Proteins; Methamphetamine; Mice; Motor Activity; Neostriatum; Nerve Tissue Proteins; Protein Binding	1997
Alteration of neurotensin receptors in MPTP-treated mice. Peptides, 1999, Volume: 20, Issue:7 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Autoradiography; Corpus Striatum; Dopamine; Dopamine Uptake Inhibitors; Kinetics; Male; Mazindol; Mice; Mice, Inbred C57BL; MPTP Poisoning; Neurotensin; Neurotoxins; Parkinson Disease; Receptors, Neurotensin; Substantia Nigra	1999
Effects of GM1 ganglioside treatment on pre- and postsynaptic dopaminergic markers in the striatum of parkinsonian monkeys. Synapse (New York, N.Y.), 2000, Volume: 36, Issue:2 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Benzazepines; Binding Sites; Dopamine Agents; Dopamine Antagonists; Dopamine Uptake Inhibitors; G(M1) Ganglioside; Mazindol; Neostriatum; Parkinsonian Disorders; Radioligand Assay; Receptors, Dopamine; Receptors, Dopamine D1; Receptors, Dopamine D2; Recovery of Function; Saimiri; Spiperone; Synapses	2000
Chronic supranigral infusion of BDNF in normal and MPTP-treated common marmosets. Journal of neural transmission (Vienna, Austria : 1996), 1999, Volume: 106, Issue:7-8 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Brain-Derived Neurotrophic Factor; Callithrix; Dopamine Agents; Dopamine Uptake Inhibitors; Glutamate Decarboxylase; Mazindol; Motor Activity; Parkinsonian Disorders; Striatonigral Degeneration; Substantia Nigra; Tyrosine 3-Monooxygenase	1999
Expression of striatal preprotachykinin mRNA in symptomatic and asymptomatic 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-exposed monkeys is related to parkinsonian motor signs. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2001, Jul-01, Volume: 21, Issue:13 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Autoradiography; Cognition Disorders; Corpus Striatum; Disease Models, Animal; Dose-Response Relationship, Drug; Gene Expression Regulation; In Situ Hybridization; Macaca; Male; Mazindol; Parkinson Disease, Secondary; Predictive Value of Tests; Protein Precursors; RNA, Messenger; Severity of Illness Index; Tachykinins; Tritium	2001
Caffeine's neuroprotection against 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine toxicity shows no tolerance to chronic caffeine administration in mice. Neuroscience letters, 2002, Mar-29, Volume: 322, Issue:1 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Binding Sites; Caffeine; Dopamine; Dopamine Agents; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Drug Administration Schedule; Drug Tolerance; Male; Mazindol; Membrane Glycoproteins; Membrane Transport Proteins; Mice; Mice, Inbred C57BL; Motor Activity; Neostriatum; Nerve Tissue Proteins; Neurons; Neuroprotective Agents; Neurotoxins; Parkinsonian Disorders; Purinergic P1 Receptor Antagonists; Radioligand Assay; Receptor, Adenosine A2A; Receptors, Purinergic P1; Tritium	2002
Alterations in m-RNA expression for Cu,Zn-superoxide dismutase and glutathione peroxidase in the basal ganglia of MPTP-treated marmosets and patients with Parkinson's disease. Brain research, 2003, Apr-11, Volume: 968, Issue:2 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Adrenergic Uptake Inhibitors; Adult; Aged; Aged, 80 and over; Animals; Autoradiography; Basal Ganglia; Brain Mapping; Callithrix; Female; Glutathione Peroxidase; Humans; In Situ Hybridization; Male; Mazindol; Neural Pathways; Parkinson Disease; RNA, Messenger; Substantia Nigra; Superoxide Dismutase; Tissue Distribution; Tritium	2003
Rapid reduction of ATP synthesis and lack of free radical formation by MPP+ in rat brain synaptosomes and mitochondria. Brain research, 2003, Jun-13, Volume: 975, Issue:1-2 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Adenosine Triphosphate; Animals; Antioxidants; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Cyclic N-Oxides; Dopamine; Dopamine Agents; Dopamine Uptake Inhibitors; Free Radicals; In Vitro Techniques; Male; Mazindol; Mitochondria; Neostriatum; Nitrogen Oxides; Organometallic Compounds; Pyridinium Compounds; Rats; Rats, Sprague-Dawley; Rotenone; Salicylates; Subcellular Fractions; Synaptosomes; Uncoupling Agents	2003