matrine, (5beta)-isomer has been researched along with camptothecin in 3 studies
| Studies (matrine, (5beta)-isomer) | Trials (matrine, (5beta)-isomer) | Recent Studies (post-2010) (matrine, (5beta)-isomer) | Studies (camptothecin) | Trials (camptothecin) | Recent Studies (post-2010) (camptothecin) |
|---|---|---|---|---|---|
| 11 | 0 | 11 | 13,002 | 2,229 | 5,391 |
| Protein | Taxonomy | matrine, (5beta)-isomer (IC50) | camptothecin (IC50) |
|---|---|---|---|
| Histone deacetylase 3 | Homo sapiens (human) | 0.05 | |
| Multidrug resistance-associated protein 4 | Homo sapiens (human) | 7.4 | |
| DNA topoisomerase 1 | Homo sapiens (human) | 1.9799 | |
| Somatostatin receptor type 1 | Homo sapiens (human) | 0.0022 | |
| Somatostatin receptor type 2 | Homo sapiens (human) | 0.0022 | |
| Somatostatin receptor type 4 | Homo sapiens (human) | 0.0022 | |
| Somatostatin receptor type 3 | Homo sapiens (human) | 0.0022 | |
| Somatostatin receptor type 5 | Homo sapiens (human) | 0.0022 | |
| 5-hydroxytryptamine receptor 2B | Homo sapiens (human) | 0.97 | |
| Histone deacetylase 4 | Homo sapiens (human) | 0.05 | |
| Histone deacetylase 1 | Homo sapiens (human) | 0.05 | |
| Histone deacetylase 7 | Homo sapiens (human) | 0.05 | |
| Histone deacetylase 2 | Homo sapiens (human) | 0.05 | |
| Polyamine deacetylase HDAC10 | Homo sapiens (human) | 0.05 | |
| Histone deacetylase 11 | Homo sapiens (human) | 0.05 | |
| Histone deacetylase 8 | Homo sapiens (human) | 0.05 | |
| Histone deacetylase 6 | Homo sapiens (human) | 0.05 | |
| Histone deacetylase 9 | Homo sapiens (human) | 0.05 | |
| Histone deacetylase 5 | Homo sapiens (human) | 0.05 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, R; Jiang, J; Jing, D; Liu, X; Rashid, HU; Wang, L; Xie, P; Xu, Y | 1 |
| Jiang, J; Jing, D; Liang, X; Liu, X; Rashid, HU; Wang, H; Wang, L; Wu, L; Xie, P; Xu, Y | 1 |
| Cai, B; Huang, M; Jiang, J; Li, Z; Luo, M; Wang, L; Wu, L | 1 |
3 other study(ies) available for matrine, (5beta)-isomer and camptothecin
| Article | Year |
|---|---|
Design, synthesis and evaluation of novel sophoridinic imine derivatives containing conjugated planar structure as potent anticancer agents.
Topics: Alkaloids; Antineoplastic Agents; Cell Cycle; Cell Proliferation; DNA Topoisomerases, Type I; Dose-Response Relationship, Drug; Drug Design; Drug Screening Assays, Antitumor; HeLa Cells; Hep G2 Cells; Humans; Imines; Matrines; Molecular Docking Simulation; Molecular Structure; Quinolizines; Structure-Activity Relationship; Topoisomerase I Inhibitors | 2018 |
Novel indolo-sophoridinic scaffold as Topo I inhibitors: Design, synthesis and biological evaluation as anticancer agents.
Topics: Animals; Antineoplastic Agents; Cell Cycle Checkpoints; Cell Proliferation; Drug Design; Female; Hep G2 Cells; Humans; Indoles; Liver Neoplasms; Mice; Mice, Inbred BALB C; Molecular Docking Simulation; Structure-Activity Relationship; Topoisomerase I Inhibitors | 2018 |
Design, synthesis, biological evaluation and structure-activity relationship of sophoridine derivatives bearing pyrrole or indole scaffold as potential antitumor agents.
Topics: Alkaloids; Animals; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Drug Design; Drug Screening Assays, Antitumor; Humans; Indoles; Liver Neoplasms, Experimental; Matrines; Mice; Molecular Docking Simulation; Molecular Structure; Pyrroles; Quinolizines; Structure-Activity Relationship | 2018 |