mast-cell-degranulating-peptide and noxiustoxin

mast-cell-degranulating-peptide has been researched along with noxiustoxin* in 2 studies

Reviews

1 review(s) available for mast-cell-degranulating-peptide and noxiustoxin

ArticleYear
Potassium channel toxins and transmitter release.
    Annals of the New York Academy of Sciences, 1994, Mar-09, Volume: 710

    Topics: Amino Acid Sequence; Animals; Bee Venoms; Elapid Venoms; Molecular Sequence Data; Neurotoxins; Peptides; Potassium Channels; Scorpion Venoms; Sequence Homology, Amino Acid; Toxins, Biological; Venoms

1994

Other Studies

1 other study(ies) available for mast-cell-degranulating-peptide and noxiustoxin

ArticleYear
Pharmacological characterization of five cloned voltage-gated K+ channels, types Kv1.1, 1.2, 1.3, 1.5, and 3.1, stably expressed in mammalian cell lines.
    Molecular pharmacology, 1994, Volume: 45, Issue:6

    We have analyzed the biophysical and pharmacological properties of five cloned K+ (Kv) channels (Kv1.1, Kv1.2, Kv1.3, Kv1.5, and Kv3.1) stably expressed in mammalian cell lines. Kv1.1 is biophysically similar to a K+ channel in C6 glioma cells and astrocytes, Kv1.3 and Kv3.1 have electrophysiological properties identical to those of the types n and l K+ channels in T cells, respectively, and Kv1.5 closely resembles a rapidly activating delayed rectifier in the heart. Each of these native channels may be formed from the homomultimeric association of the corresponding Kv subunits, and pharmacological compounds that selectively modulate them may be useful for the treatment of neurological, immune, and cardiac disorders. The cell lines described in this report could be used to identify such drugs and we have therefore embarked on a pharmacological characterization of the five cloned channels. The compounds tested in this study include 4-aminopyridine, capsaicin, charybdotoxin, cromakalim, dendrotoxin, diltiazem, D-sotalol, flecainide, kaliotoxin, mast cell degranulating peptide, nifedipine, noxiustoxin, resiniferatoxin, and tetraethylammonium.

    Topics: 3T3 Cells; Animals; Base Sequence; Benzopyrans; Capsaicin; Cell Line; Cells, Cultured; Charybdotoxin; Cloning, Molecular; Cromakalim; Diltiazem; Diterpenes; Elapid Venoms; Flecainide; Ion Channel Gating; Mice; Molecular Sequence Data; Nifedipine; Oligodeoxyribonucleotides; Peptides; Potassium Channels; Pyrroles; Scorpion Venoms; Sotalol

1994