Page last updated: 2024-08-25

maslinic acid and oleanolic acid

maslinic acid has been researched along with oleanolic acid in 77 studies

Research

Studies (77)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's17 (22.08)29.6817
2010's50 (64.94)24.3611
2020's10 (12.99)2.80

Authors

AuthorsStudies
Alexacou, KM; Cheng, K; Gimisis, T; Hao, J; Hayes, JM; Leonidas, DD; Liu, J; Ni, P; Oikonomakos, NG; Sun, H; Wen, X; Zhang, L; Zhang, P; Zographos, SE1
Acebey-Castellon, IL; Bouthagane, N; Doan Thi Mai, H; Gangloff, SC; Hung, NV; Lavaud, C; Le Magrex Debar, E; Litaudon, M; Muhammad, D; Roseau, N; Sevenet, T; Voutquenne-Nazabadioko, L1
Chen, J; Chen, L; Cheng, K; Gong, Y; Hao, J; Jiang, H; Li, H; Li, L; Liang, Z; Liu, H; Liu, J; Luo, C; Sun, H; Wen, X; Zhang, L; Zhang, P; Zhang, X; Zheng, M; Zhu, X1
El-Kabbani, O; Endo, S; Hara, A; Iinuma, M; Matsunaga, T; Soda, M; Tajima, K; Takemura, M; Zhao, HT1
Garcia-Granados, A; Martin-Fonseca, S; Martinez, A; Parra, A; Rivas, F1
Chen, K; Huang, X; Peng, Y; Qiu, Y; Shi, Y; Sun, D; Wang, H; Wang, Q; Xiao, S; Yu, F; Yu, M; Zhang, C; Zhang, L; Zhang, Z; Zhao, C; Zheng, Y; Zhou, D; Zhu, L1
Csuk, R; Köwitsch, A; Siewert, B; Wiemann, J1
Albericio, F; Garcia-Granados, A; Lupiañez, JA; Martin-Fonseca, S; Martinez, A; Medina-O'Donnell, M; Parra, A; Reyes-Zurita, FJ; Rivas, F1
Camelio, AM; Cho, J; Claussen, KR; DiGiovanni, J; Nelson, AT; Siegel, D; Tremmel, L1
Hao, XJ; Huang, LR; Li, QJ; Luo, H; Wang, DP; Yang, XS; Zhang, JX1
Ferrer-Martín, RM; Garcia-Granados, A; Lupiañez, JA; Martin-Fonseca, S; Martinez, A; Medina-O'Donnell, M; Parra, A; Reyes-Zurita, FJ; Rivas, F1
Csuk, R; Heller, L; Kuhfs, J; Sommerwerk, S1
Li, H; Tian, S; Wang, C; Wei, X; Wu, P; Xu, L; Xue, J1
Csuk, R; Heller, L; Kerzig, C; Kramell, AE; Sommerwerk, S1
Chau, VM; Do Thi, T; Doan Thi Mai, H; Litaudon, M; Nguyen, TT; Nguyen, VH; Pham, VC; Truong, BN1
Lupiañez, JA; Martinez, A; Medina-O'Donnell, M; Parra, A; Reyes-Zurita, FJ; Rivas, F1
Csuk, R; Heller, L; Wiemann, J1
Csuk, R; Fischer, L; Kahnt, M; Sommerwerk, S; Wiemann, J1
Appendino, G; Bellido, ML; Calzado, MA; Caprioglio, D; Cruz, C; Galera, N; Jinénez, C; Minassi, A; Muñoz, E; Prados, ME; Rogati, F1
Fukushima, EO; Muranaka, T; Nomura, Y; Vo, NNQ1
Chen, C; Cheng, K; Dai, L; Hu, K; Li, H; Liu, L; Sun, H; Wen, X; Xu, Q; Yuan, H1
Chang, YH; Hung, HY1
Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M1
Kim, YK; Ryu, SY; Yoon, SK1
Dobado, JA; García-Granados, A; López, PE; Melguizo, E; Moliz, JN; Parra, A; Simeó, Y1
Guo, QL; Yang, JS1
Li, ZY; Lin, HW; Shen, Y; Shu, W; Wang, QH; Zhou, JB1
Daniel, H; Juan, ME; Planas, JM; Ruiz-Gutierrez, V; Wenzel, U2
Chen, RY; Dai, C; Liu, C; Liu, P; Wang, B1
De La Puerta, R; Fernandez-Arche, A; Marquez-Martin, A; Ruiz-Gutierrez, V; Yaqoob, P1
Carvalho, J; Carvalho-Tavares, J; Hernández, M; Ibeas, E; Martín, R; Nieto, ML; Ruiz-Gutierrez, V1
Chen, JJ; Cui, Y; Lin, XK; Zhang, XM; Zhang, Y; Zhou, L1
Jang, DS; Kim, JH; Kim, JM; Kim, JS; Kim, YS; Lee, YM; Yoo, JL1
Cheng, K; Liu, J; Sun, H; Xie, J; Zhang, P1
Chen, J; Li, WL; Lv, H; Zhang, HQ1
Kang, SH; Shi, YQ; Yang, CX1
Aguilera, MP; Allouche, Y; Beltrán, G; Gaforio, JJ; Jiménez, A; Uceda, M1
Chen, G; Fan, J; Li, X; Xu, Q; Yang, S; Zhang, M1
Chieng, YC; Hong, PL; Hoon, LS; Hsum, YW; Mooi, LY; Soo, KK; Yew, WT1
Chan, CY; Huang, CY; Lin, CC; Mong, MC; Yin, MC1
Li, GL; Song, CH; Suo, YR; Xia, L; You, JM; Zheng, J1
Liu, J; Shang, J; Sun, H; Yong, Y; Zhang, L1
Chieng, YC; Hoon, LS; Hsum, YW; Mooi, LY; Soo, KK; Yew, WT1
Fang, W; Tao, J1
Bruni, R; Caligiani, A; Malavasi, G; Marseglia, A; Palla, G; Tognolini, M1
Fernandez-Vivas, A; Garcia-Granados, A; Martinez, A; Parra, A; Perojil, A; Rivas, F1
Alemany, R; Barceló, F; Gómez-Florit, M; Martín-Broto, J; Martínez-Serra, J; Obrador-Hevia, A; Ruiz-Gutiérrez, V; Villar, VH; Vögler, O1
Albericio, F; Garcia-Granados, A; Lupiañez, JA; Martin-Fonseca, S; Martinez, A; Medina-O'Donnell, M; Parra, A; Reyes-Zurita, FJ; Rivas, F; Rufino-Palomares, EE1
He, QQ; Ma, CM; Ma, JN; Yang, L; Zhang, JY1
Abderabba, M; Jiménez, AI; López-Arencibia, A; Lopez-Bazzocchi, I; Lorenzo-Morales, J; Martín-Navarro, CM; Mejri, M; Piñero, JE; Reyes-Batlle, M; Sifaoui, I; Ticona, JC; Valladares, B1
Chen, G; Hu, N; Li, G; Liu, D; Liu, S; Suo, Y; Wu, H; You, J1
Bu, HJ; Hyun, CG; Kim, JE; Kim, SY; Lee, NH1
Ding, T; Liu, M; Sun, M; Tang, Y; Wang, X1
Bianco, A; Nicoletti, M; Serafini, M; Venditti, A1
Ben Jannet, H; Chouaïb, K; Daami-Remadi, M; Elie, N; Hamza, MA; Hichri, F; Nguir, A; Touboul, D1
Lupiáñez, JA; Muñoz-Espada, I; Peragón, J; Reyes-Zurita, FJ; Rufino-Palomares, EE1
Bianco, A; Foddai, S; Frezza, C; Nicoletti, M; Riccardelli, M; Serafini, M; Venditti, A1
Ahn, YJ; Kwon, HW; Na, YE; Perumalsamy, H; Wang, X1
Cao, J; Peng, LQ; Xu, JJ1
Galisteo-González, F; Lupiañez, JA; Martinez, A; Medina-O'Donnell, M; Parra, A; Reyes-Zurita, FJ; Rivas, F1
Hai, NT; Kariyazono, H; Long, DD; Nakajima, K; Ohta, T; Oiso, S; Shoyama, Y; Tung, NH; Uto, T1
Khathi, A; Luvuno, M; Mbongwa, HP1
Guardiola, L; Hernández-Sánchez, P; López-Miranda, S; Núñez-Delicado, E1
Calleja, MA; Covas, MI; de la Torre, R; Espejo, JA; Fitó, M; Gleeson, SB; Kotronoulas, A; Marchal, R; Mesa-García, MD; Navarro, JRF; Pastor, A; Pozo, OJ; Pujadas, M; Sanchez-Rodriguez, E1
Bishayee, A; Deshmukh, RR; Kumar, P; Kumar, S; Sharma, H1
Araya, H; Ferhat, M; Fujimoto, Y; Kabouchea, Z1
Aisa, HA; Di, DL; Gong, Y; Huang, XY; Liu, JF; Pei, D; Zhang, X1
Álvarez de Cienfuegos, L; Blanco-Cabra, N; Moya-Andérico, L; Parra, A; Torrents, E; Vega-Granados, K; Vukomanovic, M1
Choi, YJ; Hwang, IH; Kim, SK; Min, BG; Na, M; Quan, KT1
Alegakis, AK; Calina, D; Docea, AO; Fragkiadaki, P; Razgonova, MP; Sarandi, E; Spandidos, DA; Thanasoula, M; Tsatsakis, A; Tsoukalas, D1
Claro-Cala, CM; de Sotomayor, MA; Herrera, MD; Miñano, J; Pérez-Montero, M; Quintela, JC; Rodríguez-Rodríguez, AR1
Biel, S; Carbó, M; Covas, MI; de la Torre, R; Díaz-Pellicer, P; Espejo, JA; Expósito, M; Fitó, M; Jimenez-Valladares, F; Mesa, MD; Pozo, O; Pujadas, M; Rosa, C; Sanchez-Rodriguez, E1
Al-Swailmi, FK; Aladaileh, S; Hf Shalayel, M; M Al-Mazaideh, G; Nour, S1
Ding, W; He, Y; Jiao, J; Li, W; Wang, Y; Yang, K; Yang, Y; Zhan, H1
Cordell, GA; Lim, YM; Ooi, KX; Poo, CL; Subramaniam, M1
Bag, BG; Banerjee, J; Das, S; Dash, SK; Giri, B; Hasan, SN; Kar, S; Napagoda, M; Patra, S; Pavithra, U; Samanta, S; Wanigasekera, D; Wijesekera, K1

Reviews

4 review(s) available for maslinic acid and oleanolic acid

ArticleYear
Recent advances in natural anti-obesity compounds and derivatives based on in vivo evidence: A mini-review.
    European journal of medicinal chemistry, 2022, Jul-05, Volume: 237

    Topics: Animals; Anti-Obesity Agents; Drug Discovery; Obesity; Phytochemicals

2022
Pentacyclic triterpenes: New tools to fight metabolic syndrome.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2018, Nov-15, Volume: 50

    Topics: Animals; Heart; Humans; Insulin Resistance; Liver; Metabolic Syndrome; Muscle, Skeletal; Oleanolic Acid; Oxidative Stress; Pentacyclic Triterpenes; Triterpenes; Ursolic Acid

2018
Maslinic Acid: A New Compound for the Treatment of Multiple Organ Diseases.
    Molecules (Basel, Switzerland), 2022, Dec-09, Volume: 27, Issue:24

    Topics: Anti-Inflammatory Agents; Antioxidants; Humans; Olea; Oleanolic Acid; Triterpenes

2022
Maslinic acid exerts anticancer effects by targeting cancer hallmarks.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2023, Volume: 110

    Topics: Antineoplastic Agents; Humans; Neoplasms; Oleanolic Acid; Triterpenes

2023

Trials

1 trial(s) available for maslinic acid and oleanolic acid

ArticleYear
Pharmacokinetics of maslinic and oleanolic acids from olive oil - Effects on endothelial function in healthy adults. A randomized, controlled, dose-response study.
    Food chemistry, 2020, Aug-30, Volume: 322

    Topics: Adult; Blood Pressure; Cross-Over Studies; Double-Blind Method; Endothelium; Female; Humans; Male; Middle Aged; Oleanolic Acid; Olive Oil; Triterpenes; Young Adult

2020

Other Studies

72 other study(ies) available for maslinic acid and oleanolic acid

ArticleYear
Naturally occurring pentacyclic triterpenes as inhibitors of glycogen phosphorylase: synthesis, structure-activity relationships, and X-ray crystallographic studies.
    Journal of medicinal chemistry, 2008, Jun-26, Volume: 51, Issue:12

    Topics: Adenosine Monophosphate; Allosteric Site; Animals; Binding Sites; Crystallography, X-Ray; Glycogen Phosphorylase; Hypoglycemic Agents; Kinetics; Models, Molecular; Muscles; Oleanolic Acid; Pentacyclic Triterpenes; Protein Binding; Protein Conformation; Rabbits; Stereoisomerism; Structure-Activity Relationship; Triterpenes

2008
Triterpenoid saponins from Symplocos lancifolia.
    Journal of natural products, 2011, Feb-25, Volume: 74, Issue:2

    Topics: Anti-Bacterial Agents; Enterococcus faecalis; Escherichia coli; Magnoliopsida; Microbial Sensitivity Tests; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Plant Leaves; Pseudomonas aeruginosa; Saponins; Staphylococcus aureus; Triterpenes; Vietnam

2011
Identification of pentacyclic triterpenes derivatives as potent inhibitors against glycogen phosphorylase based on 3D-QSAR studies.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:6

    Topics: Animals; Enzyme Inhibitors; Glycogen Phosphorylase, Muscle Form; Models, Molecular; Molecular Conformation; Muscle, Skeletal; Pentacyclic Triterpenes; Quantitative Structure-Activity Relationship; Rabbits; Stereoisomerism

2011
Selective inhibition of the tumor marker aldo-keto reductase family member 1B10 by oleanolic acid.
    Journal of natural products, 2011, May-27, Volume: 74, Issue:5

    Topics: Aldehyde Reductase; Aldo-Keto Reductases; Antineoplastic Agents, Phytogenic; Drug Resistance, Neoplasm; HeLa Cells; HT29 Cells; Humans; Mitomycin; Models, Molecular; Molecular Structure; Mutation; Oleanolic Acid; Pentacyclic Triterpenes

2011
Maslinic acid derivatives induce significant apoptosis in b16f10 murine melanoma cells.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:12

    Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Melanoma; Mice; Olea; Triterpenes

2011
Development of oleanane-type triterpenes as a new class of HCV entry inhibitors.
    Journal of medicinal chemistry, 2013, Jun-13, Volume: 56, Issue:11

    Topics: Animals; Antiviral Agents; Cell Line, Tumor; Cytotoxins; HEK293 Cells; Hemolytic Agents; Hepacivirus; Humans; Oleanolic Acid; Rabbits; Structure-Activity Relationship; Virus Internalization

2013
The chemical and biological potential of C ring modified triterpenoids.
    European journal of medicinal chemistry, 2014, Jan-24, Volume: 72

    Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; HT29 Cells; Humans; MCF-7 Cells; Mice; Molecular Conformation; NIH 3T3 Cells; Oleanolic Acid; Structure-Activity Relationship; Triterpenes; Ursolic Acid

2014
Semi-synthesis of acylated triterpenes from olive-oil industry wastes for the development of anticancer and anti-HIV agents.
    European journal of medicinal chemistry, 2014, Mar-03, Volume: 74

    Topics: Acylation; Anti-HIV Agents; Antineoplastic Agents; Apoptosis; Industrial Waste; Olive Oil; Plant Oils; Reactive Oxygen Species; Triterpenes

2014
Synthesis of oxygenated oleanolic and ursolic acid derivatives with anti-inflammatory properties.
    Bioorganic & medicinal chemistry letters, 2015, Oct-01, Volume: 25, Issue:19

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cytokines; Female; Mice; Mice, Inbred Strains; Molecular Conformation; Oleanolic Acid; Oxygen; Skin; Triterpenes; Ursolic Acid

2015
18β-Glycyrrhetinic Acid Derivatives Possessing a Trihydroxylated A Ring Are Potent Gram-Positive Antibacterial Agents.
    Journal of natural products, 2016, Apr-22, Volume: 79, Issue:4

    Topics: Ampicillin; Anti-Bacterial Agents; Bacillus subtilis; Dose-Response Relationship, Drug; Glycyrrhetinic Acid; Glycyrrhiza; Gram-Positive Bacteria; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Molecular Structure; Pseudomonas aeruginosa; Real-Time Polymerase Chain Reaction; Streptomyces; Streptomycin; Structure-Activity Relationship; Vancomycin

2016
Semi-synthesis and antiproliferative evaluation of PEGylated pentacyclic triterpenes.
    European journal of medicinal chemistry, 2016, Aug-08, Volume: 118

    Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Cycle Checkpoints; Cell Proliferation; Drug Design; HT29 Cells; Humans; Membrane Potential, Mitochondrial; Mice; Pentacyclic Triterpenes; Polyethylene Glycols

2016
Urea derivates of ursolic, oleanolic and maslinic acid induce apoptosis and are selective cytotoxic for several human tumor cell lines.
    European journal of medicinal chemistry, 2016, Aug-25, Volume: 119

    Topics: Animals; Apoptosis; Cell Line, Tumor; Cell Proliferation; Humans; Mice; NIH 3T3 Cells; Oleanolic Acid; Structure-Activity Relationship; Triterpenes; Ursolic Acid

2016
Bioactive Pentacyclic Triterpenoids from the Leaves of Cleistocalyx operculatus.
    Journal of natural products, 2016, 11-23, Volume: 79, Issue:11

    Topics: Animals; Drug Screening Assays, Antitumor; Drugs, Chinese Herbal; Hep G2 Cells; Humans; Interleukin-6; Macrophages; MCF-7 Cells; Mice; Molecular Structure; Myrtaceae; Nuclear Magnetic Resonance, Biomolecular; Oleanolic Acid; Pentacyclic Triterpenes; Plant Leaves; Triterpenes; Tumor Necrosis Factor-alpha

2016
Rhodamine B conjugates of triterpenoic acids are cytotoxic mitocans even at nanomolar concentrations.
    European journal of medicinal chemistry, 2017, Feb-15, Volume: 127

    Topics: Animals; Apoptosis; Cell Line, Tumor; Dose-Response Relationship, Drug; Humans; Hydrophobic and Hydrophilic Interactions; Mice; Mitochondria; NIH 3T3 Cells; Rhodamines; Structure-Activity Relationship; Triterpenes

2017
Cytotoxic dammarane-type triterpenoids from the leaves of Viburnum sambucinum.
    Bioorganic & medicinal chemistry letters, 2017, 04-15, Volume: 27, Issue:8

    Topics: Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Dammaranes; Drug Screening Assays, Antitumor; Humans; Neoplasms; Plant Leaves; Triterpenes; Viburnum

2017
Diamine and PEGylated-diamine conjugates of triterpenic acids as potential anticancer agents.
    European journal of medicinal chemistry, 2018, Mar-25, Volume: 148

    Topics: Antineoplastic Agents; Apoptosis; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Survival; Diamines; Humans; Membrane Potential, Mitochondrial; Oleanolic Acid; Triterpenes

2018
An access to a library of novel triterpene derivatives with a promising pharmacological potential by Ugi and Passerini multicomponent reactions.
    European journal of medicinal chemistry, 2018, Apr-25, Volume: 150

    Topics: Animals; Cell Death; Cell Line, Tumor; Dose-Response Relationship, Drug; Humans; Mice; Molecular Structure; NIH 3T3 Cells; Structure-Activity Relationship; Triterpenes

2018
Transformation of asiatic acid into a mitocanic, bimodal-acting rhodamine B conjugate of nanomolar cytotoxicity.
    European journal of medicinal chemistry, 2018, Nov-05, Volume: 159

    Topics: Animals; Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Mice; Molecular Structure; NIH 3T3 Cells; Pentacyclic Triterpenes; Structure-Activity Relationship

2018
Triterpenoid Hydroxamates as HIF Prolyl Hydrolase Inhibitors.
    Journal of natural products, 2018, 10-26, Volume: 81, Issue:10

    Topics: Enzyme Inhibitors; HEK293 Cells; Humans; Hypoxia-Inducible Factor-Proline Dioxygenases; NF-kappa B; Triterpenes

2018
Structure-Activity Relationships of Pentacyclic Triterpenoids as Inhibitors of Cyclooxygenase and Lipoxygenase Enzymes.
    Journal of natural products, 2019, 12-27, Volume: 82, Issue:12

    Topics: Cyclooxygenase Inhibitors; Drug Evaluation, Preclinical; Humans; Lipoxygenase Inhibitors; Pentacyclic Triterpenes; Structure-Activity Relationship

2019
Synthesis and anti-inflammatory activity of saponin derivatives of δ-oleanolic acid.
    European journal of medicinal chemistry, 2021, Jan-01, Volume: 209

    Topics: Acetyl-CoA Carboxylase; AMP-Activated Protein Kinases; Animals; Anti-Inflammatory Agents; Dose-Response Relationship, Drug; Glycyrrhizic Acid; Humans; Interleukin-6; Liver; Macrophages; Male; Medicine, Chinese Traditional; Mice; Mice, Inbred BALB C; Oleanolic Acid; Pentacyclic Triterpenes; Phosphorylation; Sapogenins; Saponins; Tumor Necrosis Factor-alpha

2021
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
    Disease models & mechanisms, 2023, 03-01, Volume: 16, Issue:3

    Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries

2023
Cytotoxic triterpenes from stem bark of Physocarpus intermedius.
    Planta medica, 2000, Volume: 66, Issue:5

    Topics: Antineoplastic Agents, Phytogenic; Betulinic Acid; Humans; Magnetic Resonance Spectroscopy; Oleanolic Acid; Pentacyclic Triterpenes; Plant Stems; Rosales; Triterpenes; Tumor Cells, Cultured; Ursolic Acid

2000
Epoxides, cyclic sulfites, and sulfate from natural pentacyclic triterpenoids: theoretical calculations and chemical transformations.
    The Journal of organic chemistry, 2003, Jun-13, Volume: 68, Issue:12

    Topics: Aza Compounds; Crystallography, X-Ray; Cyclization; Epoxy Compounds; Models, Theoretical; Molecular Structure; Oleanolic Acid; Stereoisomerism; Sulfates; Sulfites; Triterpenes

2003
[Studies on chemical constituents in fruit of Rubus chingii].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2005, Volume: 30, Issue:3

    Topics: Fruit; Oleanolic Acid; Plants, Medicinal; Rosaceae; Triterpenes; Ursolic Acid

2005
[Study on chemical constituents of Potentilla chinensis Ser].
    Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 2006, Volume: 29, Issue:3

    Topics: Flavones; Flavonoids; Molecular Structure; Oleanolic Acid; Plants, Medicinal; Potentilla; Sitosterols; Triterpenes

2006
Olive fruit extracts inhibit proliferation and induce apoptosis in HT-29 human colon cancer cells.
    The Journal of nutrition, 2006, Volume: 136, Issue:10

    Topics: Apoptosis; Caspase 3; Caspases; Cell Division; Cell Membrane Permeability; DNA Fragmentation; Enzyme Activation; Fruit; HT29 Cells; Humans; Microscopy, Confocal; Olea; Oleanolic Acid; Plant Extracts; Triterpenes

2006
[Studies on chemical constituents from moss Rhodobryum roseum II].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2006, Volume: 31, Issue:13

    Topics: Apigenin; Bryopsida; Oleanolic Acid; Plants, Medicinal; Triterpenes

2006
Modulation of cytokine secretion by pentacyclic triterpenes from olive pomace oil in human mononuclear cells.
    Cytokine, 2006, Volume: 36, Issue:5-6

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Chemokine CCL1; Chemokine CXCL9; Chemokines, CC; Chemokines, CXC; Cytokines; Dose-Response Relationship, Drug; Humans; Interleukin-1beta; Interleukin-6; Leukocytes, Mononuclear; Oleanolic Acid; Olive Oil; Plant Oils; Triterpenes; Tumor Necrosis Factor-alpha

2006
Acidic triterpenes compromise growth and survival of astrocytoma cell lines by regulating reactive oxygen species accumulation.
    Cancer research, 2007, Apr-15, Volume: 67, Issue:8

    Topics: Apoptosis; Astrocytoma; Brain Neoplasms; Cell Growth Processes; Cell Line, Tumor; Cell Survival; Cytoskeleton; Dose-Response Relationship, Drug; Humans; Membrane Potential, Mitochondrial; Oleanolic Acid; Reactive Oxygen Species; Triterpenes

2007
[Chemical constituents from root of Actinidia chinensis].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2007, Volume: 32, Issue:16

    Topics: Actinidia; Oleanolic Acid; Plant Roots; Plants, Medicinal; Sitosterols; Triterpenes

2007
Aldose-reductase- and protein-glycation-inhibitory principles from the whole plant of Duchesnea chrysantha.
    Chemistry & biodiversity, 2008, Volume: 5, Issue:2

    Topics: Aldehyde Reductase; Animals; Apigenin; Ellagic Acid; Glycation End Products, Advanced; Glycosides; Lens, Crystalline; Molecular Structure; Oleanolic Acid; Quercetin; Rats; Rats, Sprague-Dawley; Rosaceae; Stereoisomerism; Structure-Activity Relationship; Triterpenes; Ursolic Acid

2008
Antiproliferative and apoptosis-inducing effects of maslinic and oleanolic acids, two pentacyclic triterpenes from olives, on HT-29 colon cancer cells.
    The British journal of nutrition, 2008, Volume: 100, Issue:1

    Topics: Antineoplastic Agents; Apoptosis; Caspase 3; Cell Death; Cell Membrane Permeability; Cell Proliferation; Colonic Neoplasms; DNA Fragmentation; DNA, Neoplasm; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; HT29 Cells; Humans; Necrosis; Olea; Oleanolic Acid; Reactive Oxygen Species; Triterpenes

2008
Practical synthesis of bredemolic acid, a natural inhibitor of glycogen phosphorylase.
    Journal of natural products, 2008, Volume: 71, Issue:11

    Topics: Animals; Glycogen Phosphorylase; Muscles; Oleanolic Acid; Rabbits; Stereoisomerism; Triterpenes

2008
[Studies on the triterpenes from loquat leaf (Eriobotrya japonica)].
    Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 2008, Volume: 31, Issue:9

    Topics: Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Molecular Structure; Oleanolic Acid; Plant Leaves; Plants, Medicinal; Rosaceae; Triterpenes; Ursolic Acid

2008
[Triterpenoids and steroids of root of Rubus biflorus].
    Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 2008, Volume: 31, Issue:11

    Topics: Magnetic Resonance Spectroscopy; Molecular Structure; Oleanolic Acid; Plant Roots; Plants, Medicinal; Rosaceae; Sitosterols; Steroids; Triterpenes

2008
Triterpenic content and chemometric analysis of virgin olive oils from forty olive cultivars.
    Journal of agricultural and food chemistry, 2009, May-13, Volume: 57, Issue:9

    Topics: Fruit; Olea; Oleanolic Acid; Olive Oil; Plant Oils; Species Specificity; Triterpenes; Ursolic Acid

2009
[Chemical constituents of roots of Boehmeria nivea].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2009, Volume: 34, Issue:20

    Topics: Boehmeria; Drugs, Chinese Herbal; Oleanolic Acid; Plant Roots; Triterpenes

2009
Cancer chemopreventive activity of maslinic acid: suppression of COX-2 expression and inhibition of NF-κB and AP-1 activation in Raji cells.
    Planta medica, 2011, Volume: 77, Issue:2

    Topics: Anti-Inflammatory Agents; Anticarcinogenic Agents; Cell Line, Tumor; Cell Proliferation; Cyclooxygenase 2; Electrophoretic Mobility Shift Assay; Gene Expression; Humans; Lymphoma; NF-kappa B; Oleanolic Acid; Signal Transduction; Transcription Factor AP-1; Triterpenes

2011
Antiangiogenic potential of three triterpenic acids in human liver cancer cells.
    Journal of agricultural and food chemistry, 2011, Jan-26, Volume: 59, Issue:2

    Topics: Angiogenesis Inhibitors; Cell Line, Tumor; Fibroblast Growth Factor 2; Gene Expression; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Interleukin-8; Liver Neoplasms; Oleanolic Acid; Triterpenes; Ursolic Acid

2011
Development of a new HPLC method with precolumn fluorescent derivatization for rapid, selective and sensitive detection of triterpenic acids in fruits.
    Journal of agricultural and food chemistry, 2011, Apr-13, Volume: 59, Issue:7

    Topics: Betulinic Acid; Chromatography, High Pressure Liquid; Fluorescent Dyes; Food Analysis; Fruit; Oleanolic Acid; Pentacyclic Triterpenes; Triterpenes; Ursolic Acid

2011
Effect of olive pomace extracts on hyperlipidaemia.
    Natural product research, 2011, Volume: 25, Issue:12

    Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Cholesterol; Fruit; Hyperlipidemias; Hypolipidemic Agents; Male; Molecular Structure; Olea; Oleanolic Acid; Phytotherapy; Plant Extracts; Rats; Rats, Sprague-Dawley; Triglycerides; Triterpenes

2011
Suppressive effect of maslinic acid on PMA-induced protein kinase C in human B-lymphoblastoid cells.
    Asian Pacific journal of cancer prevention : APJCP, 2012, Volume: 13, Issue:4

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Acetophenones; Anticarcinogenic Agents; Benzopyrans; Cells, Cultured; Enzyme Inhibitors; Humans; Inhibitory Concentration 50; Isoenzymes; Oleanolic Acid; Precursor Cells, B-Lymphoid; Protein Kinase C; Sphingosine; Staurosporine; Tetradecanoylphorbol Acetate; Triterpenes; Ursolic Acid

2012
[Chemical constituents from Sambucus chinensis].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2012, Volume: 37, Issue:10

    Topics: Oleanolic Acid; Sambucus; Triterpenes

2012
A simple GC-MS method for the screening of betulinic, corosolic, maslinic, oleanolic and ursolic acid contents in commercial botanicals used as food supplement ingredients.
    Food chemistry, 2013, Jan-15, Volume: 136, Issue:2

    Topics: Betulinic Acid; Dietary Supplements; Gas Chromatography-Mass Spectrometry; Oleanolic Acid; Pentacyclic Triterpenes; Plant Extracts; Plants; Triterpenes; Ursolic Acid

2013
Biotransformation of oleanolic and maslinic acids by Rhizomucor miehei.
    Phytochemistry, 2013, Volume: 94

    Topics: Biotransformation; Magnetic Resonance Spectroscopy; Models, Chemical; Molecular Structure; Oleanolic Acid; Rhizomucor; Triterpenes

2013
Oleanolic and maslinic acid sensitize soft tissue sarcoma cells to doxorubicin by inhibiting the multidrug resistance protein MRP-1, but not P-glycoprotein.
    The Journal of nutritional biochemistry, 2014, Volume: 25, Issue:4

    Topics: Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Line, Tumor; Cell Survival; Dose-Response Relationship, Drug; Doxorubicin; Drug Resistance, Neoplasm; Glutathione; Humans; Multidrug Resistance-Associated Proteins; Oleanolic Acid; Sarcoma; Sarcoma, Synovial; Triterpenes

2014
Solid-phase library synthesis of bi-functional derivatives of oleanolic and maslinic acids and their cytotoxicity on three cancer cell lines.
    ACS combinatorial science, 2014, Aug-11, Volume: 16, Issue:8

    Topics: Acylation; Antineoplastic Agents; Cell Line, Tumor; Combinatorial Chemistry Techniques; Humans; Neoplasms; Oleanolic Acid; Solid-Phase Synthesis Techniques; Triterpenes

2014
Chemical constituents of gold-red apple and their α-glucosidase inhibitory activities.
    Journal of food science, 2014, Volume: 79, Issue:10

    Topics: alpha-Glucosidases; alpha-Linolenic Acid; Betulinic Acid; Fruit; Glycoside Hydrolase Inhibitors; Magnetic Resonance Spectroscopy; Malus; Oleanolic Acid; Pentacyclic Triterpenes; Spectrometry, Mass, Electrospray Ionization; Triterpenes; Ursolic Acid

2014
In vitro effects of triterpenic acids from olive leaf extracts on the mitochondrial membrane potential of promastigote stage of Leishmania spp.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2014, Oct-15, Volume: 21, Issue:12

    Topics: Adenosine Triphosphate; Antiprotozoal Agents; Cell Membrane Permeability; Leishmania; Membrane Potential, Mitochondrial; Molecular Structure; Olea; Oleanolic Acid; Plant Extracts; Plant Leaves; Triterpenes

2014
Simultaneous determination of six triterpenic acids in some Chinese medicinal herbs using ultrasound-assisted dispersive liquid-liquid microextraction and high-performance liquid chromatography with fluorescence detection.
    Journal of pharmaceutical and biomedical analysis, 2015, Mar-25, Volume: 107

    Topics: Betulinic Acid; Chromatography, High Pressure Liquid; Fluorescence; Limit of Detection; Liquid Phase Microextraction; Medicine, Chinese Traditional; Oleanolic Acid; Pentacyclic Triterpenes; Plants, Medicinal; Solvents; Triterpenes; Ultrasonics; Ursolic Acid

2015
Chemical constituents of Tilia taquetii leaves and their inhibition of MMP-1 expression and elastase activities.
    Natural product communications, 2014, Volume: 9, Issue:12

    Topics: Humans; Matrix Metalloproteinase 1; Matrix Metalloproteinase Inhibitors; Oleanolic Acid; Pancreatic Elastase; Plant Extracts; Plant Leaves; Quercetin; Skin Aging; Tilia; Triterpenes

2014
Investigation of cytochrome P450 inhibitory properties of maslinic acid, a bioactive compound from Olea europaea L., and its structure-activity relationship.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2015, Jan-15, Volume: 22, Issue:1

    Topics: Animals; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Humans; Inhibitory Concentration 50; Male; Microsomes, Liver; Olea; Oleanolic Acid; Rats, Sprague-Dawley; Structure-Activity Relationship; Triterpenes

2015
Terpenoids of Linaria alpina (L.) Mill. from Dolomites, Italy.
    Natural product research, 2015, Volume: 29, Issue:21

    Topics: Flavonoids; Iridoid Glucosides; Italy; Linaria; Molecular Structure; Oleanolic Acid; Phytochemicals; Plant Components, Aerial; Plant Extracts; Terpenes; Triterpenes; Ursolic Acid

2015
Semi-synthesis of new antimicrobial esters from the natural oleanolic and maslinic acids.
    Food chemistry, 2015, Sep-15, Volume: 183

    Topics: Anti-Infective Agents; Esters; Oleanolic Acid; Triterpenes

2015
A New HPLC-MS Method for Measuring Maslinic Acid and Oleanolic Acid in HT29 and HepG2 Human Cancer Cells.
    International journal of molecular sciences, 2015, Sep-09, Volume: 16, Issue:9

    Topics: Cell Proliferation; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Hep G2 Cells; HT29 Cells; Humans; Mass Spectrometry; Oleanolic Acid; Triterpenes

2015
Unusual molecular pattern in Ajugoideae subfamily: the case of Ajuga genevensis L. from Dolomites.
    Natural product research, 2016, Volume: 30, Issue:9

    Topics: Ajuga; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents, Phytogenic; Antioxidants; Cinnamates; Depsides; Iridoid Glucosides; Iridoids; Italy; Medicine, Traditional; Neuroprotective Agents; Oleanolic Acid; Plant Extracts; Rosmarinic Acid; Triterpenes

2016
Effects and possible mechanisms of action of acacetin on the behavior and eye morphology of Drosophila models of Alzheimer's disease.
    Scientific reports, 2015, Nov-04, Volume: 5

    Topics: Agastache; Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Amyloid Precursor Protein Secretases; Animals; Animals, Genetically Modified; Behavior, Animal; Disease Models, Animal; Drosophila; Eating; Eye; Flavones; Fluorescence Resonance Energy Transfer; Gene Expression Regulation; Humans; Longevity; Male; Oleanolic Acid; Phenotype; Triterpenes

2015
Microcrystalline cellulose based matrix solid phase dispersion microextration for isomeric triterpenoid acids in loquat leaves by ultrahigh-performance liquid chromatography and quadrupole time-of-flight mass spectrometry.
    Journal of chromatography. A, 2016, Nov-11, Volume: 1472

    Topics: Cellulose; Chromatography, High Pressure Liquid; Eriobotrya; Isomerism; Limit of Detection; Oleanolic Acid; Plant Leaves; Solid Phase Extraction; Solvents; Tandem Mass Spectrometry; Triterpenes; Ursolic Acid

2016
Synthesis and in vitro antiproliferative evaluation of PEGylated triterpene acids.
    Fitoterapia, 2017, Volume: 120

    Topics: Antineoplastic Agents; Apoptosis; Cell Cycle Checkpoints; Cell Line, Tumor; HT29 Cells; Humans; Membrane Potential, Mitochondrial; Oleanolic Acid; Polyethylene Glycols; Triterpenes

2017
Bioactive Triterpenes from the Root of Salvia miltiorrhiza Bunge.
    Phytotherapy research : PTR, 2017, Volume: 31, Issue:9

    Topics: Drugs, Chinese Herbal; Ghrelin; HL-60 Cells; Humans; Molecular Structure; Oleanolic Acid; Plant Roots; Salvia miltiorrhiza; Triterpenes; Ursolic Acid

2017
THE EFFECTS OF
    African journal of traditional, complementary, and alternative medicines : AJTCAM, 2016, Volume: 13, Issue:4

    Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Eating; Gastrointestinal Tract; Ghrelin; Humans; Male; Oleanolic Acid; Plant Extracts; Rats; Rats, Sprague-Dawley; Syzygium; Triterpenes

2016
Complexation between oleanolic and maslinic acids with native and modified cyclodextrins.
    Food chemistry, 2018, Feb-01, Volume: 240

    Topics: Cyclodextrins; Oleanolic Acid; Solubility; Triterpenes

2018
Liquid chromatography tandem mass spectrometric determination of triterpenes in human fluids: Evaluation of markers of dietary intake of olive oil and metabolic disposition of oleanolic acid and maslinic acid in humans.
    Analytica chimica acta, 2017, Oct-16, Volume: 990

    Topics: Chromatography, Liquid; Diet; Humans; Oleanolic Acid; Olive Oil; Tandem Mass Spectrometry; Triterpenes

2017
Two New Triterpenes and Other Compounds from Mentha aquatica (Lamiaceae).
    Natural product communications, 2017, Volume: 12, Issue:4

    Topics: Mentha; Molecular Structure; Oleanolic Acid; Plant Extracts; Plants, Medicinal; Triterpenes; Ursolic Acid

2017
Continuous separation of maslinic and oleanolic acids from olive pulp by high-speed countercurrent chromatography with elution-extrusion mode.
    Journal of separation science, 2019, Volume: 42, Issue:11

    Topics: Countercurrent Distribution; Fruit; Olea; Oleanolic Acid; Plant Extracts; Triterpenes; Waste Products

2019
Novel Oleanolic and Maslinic Acid Derivatives as a Promising Treatment against Bacterial Biofilm in Nosocomial Infections: An in Vitro and in Vivo Study.
    ACS infectious diseases, 2019, 09-13, Volume: 5, Issue:9

    Topics: Animals; Bacterial Outer Membrane; Biofilms; Cross Infection; Disease Models, Animal; Gram-Positive Bacteria; Gram-Positive Bacterial Infections; Lepidoptera; Microbial Sensitivity Tests; Molecular Structure; Oleanolic Acid; Pentacyclic Triterpenes; Triterpenes

2019
Oleanane triterpenoids from
    Natural product research, 2021, Volume: 35, Issue:8

    Topics: Humans; Hydroxyeicosatetraenoic Acids; Magnetic Resonance Spectroscopy; Microsomes; Molecular Structure; Oleanolic Acid; Plant Roots; Rubia; Structure-Activity Relationship; Triterpenes

2021
Discovery of potent telomerase activators: Unfolding new therapeutic and anti-aging perspectives.
    Molecular medicine reports, 2019, Volume: 20, Issue:4

    Topics: Astragalus Plant; Cells, Cultured; Cellular Senescence; Centella; Drug Discovery; Enzyme Activators; Humans; Leukocytes, Mononuclear; Oleanolic Acid; Plant Extracts; Telomerase; Telomere Shortening; Triterpenes

2019
Pomace Olive Oil Concentrated in Triterpenic Acids Restores Vascular Function, Glucose Tolerance and Obesity Progression in Mice.
    Nutrients, 2020, Jan-26, Volume: 12, Issue:2

    Topics: Adiposity; Animals; Aorta, Thoracic; Biomarkers; Blood Glucose; Diet, High-Fat; Diet, Mediterranean; Disease Models, Animal; Disease Progression; Insulin Resistance; Male; Mice, Inbred C57BL; Obesity; Oleanolic Acid; Olive Oil; Triterpenes; Vasoconstriction; Vasodilation; Weight Gain

2020
In silico anti-fungal efficacy and the mechanism of binding of some Syzygium aromaticum ingredient compounds to aspartate semialdehyde dehydrogenase, 6C8W and 6C85, enzymes from Blastomyces dermatitidis.
    Pakistan journal of pharmaceutical sciences, 2021, Volume: 34, Issue:6

    Topics: Antifungal Agents; Aspartate-Semialdehyde Dehydrogenase; Blastomyces; Catalytic Domain; Enzyme Inhibitors; Fungal Proteins; Hydrogen Bonding; Molecular Docking Simulation; Oleanolic Acid; Plant Extracts; Protein Conformation; Structure-Activity Relationship; Syzygium; Triterpenes

2021
Self-assembled renewable nano-sized pentacyclic triterpenoid maslinic acids in aqueous medium for anti-leukemic, antibacterial and biocompatibility studies: An insight into targeted proteins-compound interactions based mechanistic pathway prediction throu
    International journal of biological macromolecules, 2023, Aug-01, Volume: 245

    Topics: Anti-Bacterial Agents; Leukocytes, Mononuclear; Molecular Docking Simulation; Oleanolic Acid; Potassium; Sodium; Spectroscopy, Fourier Transform Infrared; Triterpenes

2023