Page last updated: 2024-09-05

maropitant and morphine

maropitant has been researched along with morphine in 11 studies

Compound Research Comparison

Studies
(maropitant)
Trials
(maropitant)
Recent Studies (post-2010)
(maropitant)
Studies
(morphine)
Trials
(morphine)
Recent Studies (post-2010) (morphine)
74365644,2705,2008,695

Protein Interaction Comparison

ProteinTaxonomymaropitant (IC50)morphine (IC50)
Delta-type opioid receptorMus musculus (house mouse)0.2939
Delta-type opioid receptorRattus norvegicus (Norway rat)0.2278
Kappa-type opioid receptorMus musculus (house mouse)0.0828
Mu-type opioid receptorRattus norvegicus (Norway rat)0.0385
Kappa-type opioid receptorRattus norvegicus (Norway rat)0.0545
Mu-type opioid receptorHomo sapiens (human)0.122
Delta-type opioid receptorHomo sapiens (human)0.1199
Kappa-type opioid receptorCavia porcellus (domestic guinea pig)0.9308
Kappa-type opioid receptorHomo sapiens (human)0.655
Mu-type opioid receptorMus musculus (house mouse)0.3305
Mu-type opioid receptorCavia porcellus (domestic guinea pig)0.202
Beta-2 adrenergic receptorCavia porcellus (domestic guinea pig)0.25

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's9 (81.82)24.3611
2020's2 (18.18)2.80

Authors

AuthorsStudies
Alibhai, HI; Lee, K; Mathis, A1
Cooke, K; Isaza, N; Koh, RB; Robertson, SA; Xie, H1
Himelfarb, MA; Litterio, NJ; Lorenzutti, AM; Martín-Flores, M; Zarazaga, MP1
Boscan, P; Marquez, M; Twedt, DC; Vogel, P; Weir, H1
Boesch, JM; Campoy, L; Gleed, RD; Kirch, PJ; Learn, MM; Martin-Flores, M; Mastrocco, A; Sakai, DM1
Boesch, JM; Campoy, L; Gleed, RD; Learn, MM; Martin-Flores, M; Mastrocco, A; Sakai, DM1
Boesch, JM; Campoy, L; Kirch, P; Learn, MM; Lorenzutti, AM; Martin-Flores, M; Mastrocco, A; Stone, M1
Himelfarb, MA; Invaldi, SH; Litterio, NJ; Lorenzutti, AM; Martín-Flores, M; Zarazaga, MP1
Chambers, P; Karna, SR; Kongara, K; Lopez-Villalobos, N; Singh, PM1
Chambers, P; Karna, SR; Kongara, K; Singh, P1
Chambers, P; Johnson, CB; Karna, SR; Kongara, K; Lopez-Villalobos, N; Singh, P; Stewart, LA1

Trials

8 trial(s) available for maropitant and morphine

ArticleYear
Effects of maropitant, acepromazine, and electroacupuncture on vomiting associated with administration of morphine in dogs.
    Journal of the American Veterinary Medical Association, 2014, Apr-01, Volume: 244, Issue:7

    Topics: Acepromazine; Analgesics, Opioid; Animals; Antiemetics; Dog Diseases; Dogs; Dopamine Antagonists; Electroacupuncture; Female; Male; Morphine; Quinuclidines; Vomiting

2014
Evaluation of the antiemetic efficacy of maropitant in dogs medicated with morphine and acepromazine.
    Veterinary anaesthesia and analgesia, 2016, Volume: 43, Issue:2

    Topics: Acepromazine; Analgesics, Opioid; Animals; Antiemetics; Dogs; Drug Interactions; Female; Male; Morphine; Prospective Studies; Quinuclidines; Salivation; Single-Blind Method; Vomiting

2016
Evaluation of oral maropitant as an antiemetic in cats receiving morphine and dexmedetomidine.
    Journal of feline medicine and surgery, 2016, Volume: 18, Issue:11

    Topics: Administration, Oral; Analgesics, Non-Narcotic; Analgesics, Opioid; Animals; Antiemetics; Cats; Dexmedetomidine; Female; Hysterectomy; Morphine; Ovariectomy; Prospective Studies; Quinuclidines; Treatment Outcome; Vomiting

2016
Effects of maropitant in cats receiving dexmedetomidine and morphine.
    Journal of the American Veterinary Medical Association, 2016, Jun-01, Volume: 248, Issue:11

    Topics: Analgesics, Non-Narcotic; Analgesics, Opioid; Animals; Antiemetics; Cat Diseases; Cats; Dexmedetomidine; Drug Interactions; Female; Injections, Intramuscular; Injections, Subcutaneous; Morphine; Nausea; Quinuclidines; Single-Blind Method; Visual Analog Scale; Vomiting

2016
Maropitant administered orally 2-2.5 h prior to morphine and dexmedetomidine reduces the incidence of emesis in cats.
    Journal of feline medicine and surgery, 2017, Volume: 19, Issue:8

    Topics: Administration, Oral; Analgesics, Opioid; Animals; Antiemetics; Cat Diseases; Cats; Dexmedetomidine; Female; Injections, Intramuscular; Morphine; Ovariectomy; Postoperative Nausea and Vomiting; Quinuclidines; Treatment Outcome

2017
A comparison between maropitant and metoclopramide for the prevention of morphine-induced nausea and vomiting in dogs.
    The Canadian veterinary journal = La revue veterinaire canadienne, 2017, Volume: 58, Issue:1

    Topics: Analgesics, Opioid; Animals; Antiemetics; Dog Diseases; Dogs; Female; Hysterectomy; Male; Metoclopramide; Morphine; Nausea; Orchiectomy; Ovariectomy; Quinuclidines; Vomiting

2017
Pharmacokinetics of morphine in combination with dexmedetomidine and maropitant following intramuscular injection in dogs anaesthetized with halothane.
    Journal of veterinary pharmacology and therapeutics, 2020, Volume: 43, Issue:2

    Topics: Analgesics, Opioid; Anesthetics, Inhalation; Animals; Antiemetics; Area Under Curve; Cross-Over Studies; Dexmedetomidine; Dogs; Drug Therapy, Combination; Half-Life; Halothane; Hypnotics and Sedatives; Injections, Intramuscular; Morphine; Quinuclidines

2020
Effect of combinations of morphine, dexmedetomidine and maropitant on the electroencephalogram in response to acute electrical stimulation in anaesthetized dogs.
    Journal of veterinary pharmacology and therapeutics, 2020, Volume: 43, Issue:6

    Topics: Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia, General; Animals; Antiemetics; Cross-Over Studies; Dexmedetomidine; Dogs; Electric Stimulation; Electroencephalography; Morphine; Quinuclidines

2020

Other Studies

3 other study(ies) available for maropitant and morphine

ArticleYear
The use of maropitant to prevent vomiting induced by epidural administration of preservative free morphine through an epidural catheter in a dog.
    Veterinary anaesthesia and analgesia, 2011, Volume: 38, Issue:5

    Topics: Anesthesia, Epidural; Animals; Antiemetics; Dog Diseases; Dogs; Male; Morphine; Narcotics; Quinuclidines; Vomiting

2011
Comparison of NK-1 Receptor Antagonist (Maropitant) to Morphine as a Pre-Anaesthetic Agent for Canine Ovariohysterectomy.
    PloS one, 2015, Volume: 10, Issue:10

    Topics: Analgesics; Animals; Dogs; Female; Morphine; Ovariectomy; Pain Management; Pain Measurement; Pain, Postoperative; Premedication; Quinuclidines; Receptors, Neurokinin-1

2015
Evaluation of analgesic interaction between morphine, dexmedetomidine and maropitant using hot-plate and tail-flick tests in rats.
    Veterinary anaesthesia and analgesia, 2019, Volume: 46, Issue:4

    Topics: Analgesics, Non-Narcotic; Analgesics, Opioid; Animals; Antiemetics; Dexmedetomidine; Drug Synergism; Drug Therapy, Combination; Male; Morphine; Pain; Pain Measurement; Quinuclidines; Random Allocation; Rats; Rats, Sprague-Dawley

2019