marizomib has been researched along with angucyclinone* in 1 studies
1 other study(ies) available for marizomib and angucyclinone
| Article | Year |
|---|---|
Grisemycin, a Bridged Angucyclinone with a Methylsulfinyl Moiety from a Marine-Derived Streptomyces sp.
Grisemycin (1), the first sulfur angucyclinone with an unusual ether-bridged system, was isolated from a marine-derived Streptomyces griseus strain M268. Its novel, here cage-like, structure was determined by spectroscopic analysis and single-crystal X-ray diffraction. Compound 1 exhibited modestly selective activity against the HL-60 cell line with an IC50 value of 31.54 μM. Futhermore, the absolute stereochemistry of kiamycin (2), an 1,12-epoxybenz[a]anthracene, previously obtained from the same strain, was established by X-ray diffraction analysis. Topics: Anthraquinones; Crystallography, X-Ray; Hep G2 Cells; HL-60 Cells; Humans; Lactones; Marine Biology; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Pyrroles; Streptomyces; Streptomyces griseus | 2016 |