marinomycin-a has been researched along with stannane* in 1 studies
1 other study(ies) available for marinomycin-a and stannane
Article | Year |
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An efficient and stereoselective synthesis of the monomeric counterpart of marinomycin A.
[structure: see text] The monomeric counterpart of marinomycin A, an antitumor-antibiotic marine natural product, was synthesized efficiently in 11 steps from the commercially available ethyl (R)-(-)-3-hydroxybutyrate. The strategy was highlighted by a crucial regio- and stereoselective cross-metathesis to form the C20-C21 double bond, enantioselective allyltitanations to control the configuration of the C17, C23, and C25 stereogenic centers, and a stereocontrolled construction of the tetraene moiety based on an original Horner-Wadsworth-Emmons olefination followed by a Pd-catalyzed cross-coupling. Topics: Alkenes; Iodides; Lactones; Macrolides; Molecular Structure; Stereoisomerism; Tin Compounds | 2007 |