Compounds > marimastat
Page last updated: 2024-09-03

marimastat and thalidomide

marimastat has been researched along with thalidomide in 8 studies

Compound Research Comparison

Studies
(marimastat)		Trials
(marimastat)		Recent Studies (post-2010)
(marimastat)		Studies
(thalidomide)		Trials
(thalidomide)		Recent Studies (post-2010) (thalidomide)
21528539,7891,3854,342

Protein Interaction Comparison

ProteinTaxonomymarimastat (IC50)thalidomide (IC50)
Cereblon isoform 4Magnetospirillum gryphiswaldense7.8
Prostaglandin G/H synthase 1Ovis aries (sheep)0.37
Prostaglandin G/H synthase 2Ovis aries (sheep)0.5
DNA damage-binding protein 1Homo sapiens (human)1.38
Protein cereblonHomo sapiens (human)1.38

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (25.00)18.2507
2000's4 (50.00)29.6817
2010's1 (12.50)24.3611
2020's1 (12.50)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M1
Kuwano, M; Ono, M2
Bergen, M; Eckhardt, SG; Hidalgo, M; Holden, SN; Pierson, AS1
Augustin, HG1
Muehlbauer, PM1
Takano, S1

Reviews

6 review(s) available for marimastat and thalidomide

ArticleYear
[Development of anti tumor agents targeting angiogenesis].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1997, Volume: 24, Issue:2

    Topics: Antineoplastic Agents; Clinical Trials as Topic; Cyclohexanes; Drug Screening Assays, Antitumor; Enzyme Inhibitors; Humans; Hydroxamic Acids; Interferon-alpha; Interleukin-12; Neoplasms; Neovascularization, Pathologic; O-(Chloroacetylcarbamoyl)fumagillol; Phenylalanine; Platelet Factor 4; Polysaccharides, Bacterial; Sesquiterpenes; Thalidomide; Thiophenes; Triazines; Triazoles; Tumor Cells, Cultured

1997
[Neovascularization and tumor development].
    Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 1998, Aug-10, Volume: 87, Issue:8

    Topics: Angiostatins; Antibiotics, Antineoplastic; Antineoplastic Agents; Collagen; Cyclohexanes; Endostatins; Humans; Hydroxamic Acids; Interferons; Interleukin-12; Neoplasm Metastasis; Neoplasms; Neovascularization, Pathologic; O-(Chloroacetylcarbamoyl)fumagillol; Peptide Fragments; Phenylalanine; Plasminogen; Sesquiterpenes; Thalidomide; Thiophenes

1998
Therapeutic angiogenesis inhibitors in the treatment of cancer.
    Advances in internal medicine, 2001, Volume: 47

    Topics: 2-Methoxyestradiol; Angiogenesis Inhibitors; Antibodies, Monoclonal; Antineoplastic Agents; Collagen; Endostatins; Endothelial Growth Factors; Enzyme Inhibitors; Estradiol; Humans; Hydroxamic Acids; Lymphokines; Matrix Metalloproteinase Inhibitors; Neoplasms; Organic Chemicals; Peptide Fragments; Protein-Tyrosine Kinases; Thalidomide; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors

2001
[Angiogenesis research--quo vadis?].
    Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft, 2003, Volume: 100, Issue:2

    Topics: Adult; Angiogenesis Inhibitors; Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Apoptosis; Bevacizumab; Cell Communication; Drug Evaluation, Preclinical; Endothelial Growth Factors; Endothelium, Vascular; Enzyme Inhibitors; Ephrins; Forecasting; Growth Substances; Humans; Hydroxamic Acids; Intercellular Signaling Peptides and Proteins; Lymphokines; Metalloendopeptidases; Mice; Neoplasms; Neovascularization, Pathologic; Neovascularization, Physiologic; Phenylalanine; Randomized Controlled Trials as Topic; Receptors, Vascular Endothelial Growth Factor; Research; Signal Transduction; Thalidomide; Thiophenes; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors

2003
Anti-angiogenesis in cancer therapy.
    Seminars in oncology nursing, 2003, Volume: 19, Issue:3

    Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal; Clinical Trials as Topic; Endothelial Growth Factors; Enzyme Inhibitors; Humans; Hydroxamic Acids; Intercellular Signaling Peptides and Proteins; Interferon-alpha; Lymphokines; Neoplasms; Oncology Nursing; Thalidomide; Tissue Extracts; Treatment Outcome; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors

2003
[Anti-angiogenesis treatment for brain tumors--present and future].
    Nihon rinsho. Japanese journal of clinical medicine, 2005, Volume: 63 Suppl 9

    Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Bevacizumab; Brain Neoplasms; Clinical Trials as Topic; Combined Modality Therapy; Depression, Chemical; Fibroblast Growth Factors; Glioma; Humans; Hydroxamic Acids; Metalloproteases; Neovascularization, Pathologic; Receptors, Fibroblast Growth Factor; Receptors, Vascular Endothelial Growth Factor; Retinoids; Suramin; Thalidomide; Tumor Necrosis Factor-alpha; Vascular Endothelial Growth Factor A

2005

Other Studies

2 other study(ies) available for marimastat and thalidomide

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
    Disease models & mechanisms, 2023, 03-01, Volume: 16, Issue:3

    Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries

2023