Compounds > marimastat
Page last updated: 2024-09-03

marimastat and ilomastat

marimastat has been researched along with ilomastat in 6 studies

Compound Research Comparison

Studies
(marimastat)		Trials
(marimastat)		Recent Studies (post-2010)
(marimastat)		Studies
(ilomastat)		Trials
(ilomastat)		Recent Studies (post-2010) (ilomastat)
2152853103045

Protein Interaction Comparison

ProteinTaxonomymarimastat (IC50)ilomastat (IC50)
Disintegrin and metalloproteinase domain-containing protein 10Homo sapiens (human)0.1356
Disintegrin and metalloproteinase domain-containing protein 12Homo sapiens (human)0.0059
Prostaglandin G/H synthase 1 Bos taurus (cattle)0.0005
Prostaglandin G/H synthase 2 Bos taurus (cattle)0.0005
A disintegrin and metalloproteinase with thrombospondin motifs 4Homo sapiens (human)0.48
Interstitial collagenaseHomo sapiens (human)0.0025
72 kDa type IV collagenaseHomo sapiens (human)0.0031
Stromelysin-1Homo sapiens (human)0.0104
MatrilysinHomo sapiens (human)0.0191
Matrix metalloproteinase-9Homo sapiens (human)0.0034
Neutrophil collagenaseHomo sapiens (human)0.0054
Macrophage metalloelastaseHomo sapiens (human)0.0057
Collagenase 3Homo sapiens (human)0.0036
Matrix metalloproteinase-14Homo sapiens (human)0.0102
Matrix metalloproteinase-15Homo sapiens (human)0.006
Matrix metalloproteinase-16Homo sapiens (human)0.008
Disintegrin and metalloproteinase domain-containing protein 17Homo sapiens (human)0.1125
Disintegrin and metalloproteinase domain-containing protein 9Homo sapiens (human)0.0286
Matrix metalloproteinase-26Homo sapiens (human)0.017
Matrix metalloproteinase-17Homo sapiens (human)0.0034
A disintegrin and metalloproteinase with thrombospondin motifs 5Homo sapiens (human)0.5

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (16.67)18.2507
2000's0 (0.00)29.6817
2010's2 (33.33)24.3611
2020's3 (50.00)2.80

Authors

AuthorsStudies
Hori, N; Ikeda, S; Inoue, S; Ohishi, Y; Okada, Y; Tsujishita, H; Yamamoto, M1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Adhikari, N; Baidya, SK; Banerjee, S; Jha, T1
Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M1
Brocchini, S; Fadda, H; Karu, K; Khaw, PT; Lockwood, A; Madaan, S; Mohamed-Ahmed, AHA1
Boaretti, M; Boschi, F; Lleo, MM; Sandri, A; Signoretto, C1

Reviews

1 review(s) available for marimastat and ilomastat

ArticleYear
Selective Inhibitors of Medium-Size S1' Pocket Matrix Metalloproteinases: A Stepping Stone of Future Drug Discovery.
    Journal of medicinal chemistry, 2022, 08-25, Volume: 65, Issue:16

    Topics: Drug Discovery; Matrix Metalloproteinase Inhibitors; Matrix Metalloproteinases

2022

Other Studies

5 other study(ies) available for marimastat and ilomastat

ArticleYear
Inhibition of membrane-type 1 matrix metalloproteinase by hydroxamate inhibitors: an examination of the subsite pocket.
    Journal of medicinal chemistry, 1998, Apr-09, Volume: 41, Issue:8

    Topics: Amino Acid Sequence; Dipeptides; Humans; Hydroxamic Acids; Ligands; Matrix Metalloproteinases, Membrane-Associated; Metalloendopeptidases; Models, Molecular; Mutation; Phenylalanine; Protease Inhibitors; Protein Conformation; Structure-Activity Relationship; Thiophenes

1998
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
    Disease models & mechanisms, 2023, 03-01, Volume: 16, Issue:3

    Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries

2023
LC-MS analysis to determine the biodistribution of a polymer coated ilomastat ocular implant.
    Journal of pharmaceutical and biomedical analysis, 2018, Aug-05, Volume: 157

    Topics: Animals; Aqueous Humor; Chromatography, Liquid; Conjunctiva; Cornea; Female; Glaucoma; Hydroxamic Acids; Indoles; Polymers; Prostheses and Implants; Rabbits; Tandem Mass Spectrometry; Tissue Distribution; Vitreous Body; Wound Healing

2018
Protease inhibitors elicit anti-inflammatory effects in CF mice with Pseudomonas aeruginosa acute lung infection.
    Clinical and experimental immunology, 2021, Volume: 203, Issue:1

    Topics: Acute Disease; Animals; Cystic Fibrosis; Hydroxamic Acids; Indoles; Mice; Mice, Knockout; Pneumonia, Bacterial; Protease Inhibitors; Pseudomonas aeruginosa; Pseudomonas Infections

2021