Compounds > marimastat
Page last updated: 2024-09-03

marimastat and diclofenac

marimastat has been researched along with diclofenac in 2 studies

Compound Research Comparison

Studies
(marimastat)		Trials
(marimastat)		Recent Studies (post-2010)
(marimastat)		Studies
(diclofenac)		Trials
(diclofenac)		Recent Studies (post-2010) (diclofenac)
21528538,8741,8743,616

Protein Interaction Comparison

ProteinTaxonomymarimastat (IC50)diclofenac (IC50)
Aldo-keto reductase family 1 member B10Homo sapiens (human)1.9
Prostaglandin G/H synthase 1 Bos taurus (cattle)0.003
Prostaglandin G/H synthase 1Ovis aries (sheep)1.3376
Interleukin-8Homo sapiens (human)0.008
Prostaglandin G/H synthase 1Homo sapiens (human)0.0415
Sodium- and chloride-dependent GABA transporter 1Rattus norvegicus (Norway rat)0.5
C-X-C chemokine receptor type 1Homo sapiens (human)0.012
Sodium- and chloride-dependent GABA transporter 2Rattus norvegicus (Norway rat)0.5
Sodium- and chloride-dependent GABA transporter 3Rattus norvegicus (Norway rat)0.5
Prostaglandin G/H synthase 2Homo sapiens (human)0.4165
Prostaglandin G/H synthase 2 Rattus norvegicus (Norway rat)0.5
Sodium- and chloride-dependent betaine transporterRattus norvegicus (Norway rat)0.5
Prostaglandin G/H synthase 2Ovis aries (sheep)1.6867
Prostaglandin G/H synthase 2Mus musculus (house mouse)0.0502
Solute carrier family 22 member 6Homo sapiens (human)4
Prostaglandin G/H synthase 1 Rattus norvegicus (Norway rat)0.5
P2Y purinoceptor 12Rattus norvegicus (Norway rat)0.02

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Baldus, JE; Carroll, JN; Caspers, N; Collins, B; Collins, J; Fletcher, TR; Grapperhaus, M; Hamper, BC; Hanau, CE; Hitchcock, J; Kleine, HP; Massa, M; McDonald, J; Messing, DM; Munie, GE; Palmquist, KE; Portolan, S; Rogers, MD; Ruminski, PG; Schmidt, M; Schnute, ME; Scholten, JA; Shieh, HS; Strohbach, J; Sunyer, T; Whiteley, LO1

Other Studies

2 other study(ies) available for marimastat and diclofenac

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Discovery of N-(4-Fluoro-3-methoxybenzyl)-6-(2-(((2S,5R)-5-(hydroxymethyl)-1,4-dioxan-2-yl)methyl)-2H-tetrazol-5-yl)-2-methylpyrimidine-4-carboxamide. A Highly Selective and Orally Bioavailable Matrix Metalloproteinase-13 Inhibitor for the Potential Treat
    Journal of medicinal chemistry, 2016, Jan-14, Volume: 59, Issue:1

    Topics: Animals; Cartilage, Articular; Collagenases; Dogs; Drug Design; Humans; Kidney; Macaca fascicularis; Male; Matrix Metalloproteinase 13; Matrix Metalloproteinase Inhibitors; Models, Molecular; Organic Anion Transporters, Sodium-Independent; Osteoarthritis; Protein Binding; Pyrimidines; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship; Tetrazoles

2016