marchantin-a has been researched along with cepharanthine* in 1 studies
1 other study(ies) available for marchantin-a and cepharanthine
| Article | Year |
|---|---|
The biological activity of cyclic bis(bibenzyls): a rational approach.
The biological activities reported for marchantin A (1), a natural cyclic bis(bibenzyl), were studied in comparison with cepharanthine (2), a therapeutically useful bisbenzylisoquinoline alkaloid. Based on the examination of steric, electrostatic, and hydrophobic similarity, as well as on the comparison of biological activities, the similar therapeutic properties of 1 and 2 can be attributed to binding on a common receptor. The wide range of activity of 1 can be interpreted by a mechanism of action based on a calcium binding. Topics: Alkaloids; Animals; Anti-Infective Agents; Antineoplastic Agents, Phytogenic; Benzylisoquinolines; Bibenzyls; Catechols; Ethers, Cyclic; Humans; Mice; Molecular Conformation; Phenyl Ethers; Solubility; Structure-Activity Relationship | 1995 |