maprotiline and trazodone

maprotiline has been researched along with trazodone in 45 studies

Research

Studies (45)

TimeframeStudies, this research(%)All Research%
pre-199024 (53.33)18.7374
1990's4 (8.89)18.2507
2000's10 (22.22)29.6817
2010's7 (15.56)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY1
Johans, C; Kinnunen, PK; Söderlund, T; Suomalainen, P1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Lombardo, F; Obach, RS; Waters, NJ1
Ahman, M; Holmén, AG; Wan, H1
Gozalbes, R; Pineda-Lucena, A1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Bellman, K; Knegtel, RM; Settimo, L1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Jones, LH; Nadanaciva, S; Rana, P; Will, Y1
Cohen, LJ; Grothe, DR1
Deanović, Z; Jakovljević, M; Mück-Seler, D1
Goldman, R; Montagne, M1
Maletta, GJ1
Ostrow, D1
Brown, TM; Evans, DL; Golden, RN; Miller, H1
Hayes, PE; Kristoff, CA1
Kulig, K1
Evans, DL; Nemeroff, CB; Simon, JS1
Gorman, RL; Klein-Schwartz, W; Oderda, GM; Wedin, GP1
Blaine, JD; Levine, J; Prien, RF1
Clifford, DB; Hicks, FG; Rutherford, JL; Zorumski, CF1
Mattes, JA1
Thompson, TL1
Burchinskiĭ, SG1
Ballinger, BR; Feely, J1
Golden, RN; Potter, WZ; Rudorfer, MV1
Dominguez, RA1
Kane, JM; Lieberman, J1
Gold, MS; Lydiard, RB; Pottash, AL1
Glassman, AH1
Robinson, DS1
Grandi, M; Mauceri, P; Morini, A; Pelliccia, G1
Gever, LN1
Hollister, LE1
Settle, EC1
Glassman, AH; Preud'homme, XA1
Casis, O; Sánchez-Chapula, JA1
Beraus, W; Conca, A; Fritzsche, H; König, P; Peschina, W1
Conca, A; Hubmann, MR; König, P; Moll, W; Waschgler, R1
Ikenouchi-Sugita, A; Nakamura, J; Yoshimura, R1
Koval'chuk, VV1

Reviews

11 review(s) available for maprotiline and trazodone

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Major depression: its recognition and treatment. Part 2. Second-generation and newer antidepressants.
    American pharmacy, 1992, Volume: NS32, Issue:11

    Topics: Antidepressive Agents; Bupropion; Clomipramine; Depression; Female; Fluoxetine; Humans; Male; Maprotiline; Selective Serotonin Reuptake Inhibitors; Trazodone

1992
The new antidepressants.
    North Carolina medical journal, 1988, Volume: 49, Issue:10

    Topics: Alprazolam; Amoxapine; Antidepressive Agents; Fluoxetine; Maprotiline; Nomifensine; Seizures; Trazodone

1988
Adverse reactions to five new antidepressants.
    Clinical pharmacy, 1986, Volume: 5, Issue:6

    Topics: Acute Kidney Injury; Amoxapine; Animals; Antidepressive Agents; Bupropion; Cardiovascular Diseases; Dopamine Antagonists; Humans; Male; Maprotiline; Nomifensine; Priapism; Propiophenones; Seizures; Trazodone

1986
Management of poisoning associated with "newer" antidepressant agents.
    Annals of emergency medicine, 1986, Volume: 15, Issue:9

    Topics: Amoxapine; Antidepressive Agents; Antidepressive Agents, Tricyclic; Emergencies; Humans; Maprotiline; Structure-Activity Relationship; Trazodone

1986
[Biochemical aspects of using antidepressants in late middle age and the elderly (review)].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1983, Volume: 83, Issue:4

    Topics: Age Factors; Aged; Aging; Antidepressive Agents; Catechol O-Methyltransferase; Depression; Depressive Disorder; Epinephrine; Humans; Maprotiline; Mianserin; Middle Aged; Monoamine Oxidase; Neurotransmitter Agents; Receptors, Neurotransmitter; Serotonin; Synaptic Transmission; Trazodone

1983
Second-generation antidepressants.
    The Psychiatric clinics of North America, 1984, Volume: 7, Issue:3

    Topics: Alprazolam; Amoxapine; Antidepressive Agents; Benzodiazepines; Bupropion; Citalopram; Clinical Trials as Topic; Dopamine; Double-Blind Method; Humans; Maprotiline; Nomifensine; Norepinephrine; Propiophenones; Propylamines; Seizures; Serotonin; Trazodone; Zimeldine

1984
The efficacy of amoxapine, maprotiline, and trazodone in comparison to imipramine and amitriptyline: a review of the literature.
    Psychopharmacology bulletin, 1984,Spring, Volume: 20, Issue:2

    Topics: Amitriptyline; Amoxapine; Anthracenes; Clinical Trials as Topic; Depression; Dibenzoxazepines; Humans; Imipramine; Maprotiline; Piperazines; Time Factors; Trazodone

1984
'Second generation' antidepressant drugs.
    Psychosomatics, 1981, Volume: 22, Issue:10

    Topics: Amoxapine; Antidepressive Agents; Antidepressive Agents, Tricyclic; Clomipramine; Humans; Maprotiline; Mianserin; Nomifensine; Trazodone; Viloxazine

1981
Review of the cardiovascular effects of heterocyclic antidepressants.
    The Journal of clinical psychiatry, 1993, Volume: 54 Suppl

    Topics: Amoxapine; Antidepressive Agents; Antidepressive Agents, Tricyclic; Arrhythmias, Cardiac; Bupropion; Cardiovascular Diseases; Cardiovascular Physiological Phenomena; Cardiovascular System; Depressive Disorder; Heart; Humans; Hypotension, Orthostatic; Maprotiline; Selective Serotonin Reuptake Inhibitors; Trazodone

1993
[Review of pharmacological efficacies and side effects of antidepressants].
    Nihon rinsho. Japanese journal of clinical medicine, 2007, Volume: 65, Issue:9

    Topics: Antidepressive Agents; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Fluvoxamine; Humans; Imipramine; Maprotiline; Paroxetine; Sulpiride; Trazodone

2007

Trials

8 trial(s) available for maprotiline and trazodone

ArticleYear
Effect of antidepressant treatment on platelet 5-HT content and relation to therapeutic outcome in unipolar depressive patients.
    Journal of affective disorders, 1991, Volume: 23, Issue:3

    Topics: Adult; Aged; Amitriptyline; Antidepressive Agents; Blood Platelets; Depressive Disorder; Double-Blind Method; Female; Fluvoxamine; Humans; Male; Maprotiline; Middle Aged; Oximes; Psychiatric Status Rating Scales; Serotonin; Trazodone

1991
The new generation antidepressants: promising innovations or disappointments?
    The Journal of clinical psychiatry, 1985, Volume: 46, Issue:10 Pt 2

    Topics: Alprazolam; Antidepressive Agents; Benzodiazepines; Bupropion; Citalopram; Clinical Trials as Topic; Depressive Disorder; Dopamine; Drug Evaluation; Fluoxetine; Humans; Maprotiline; Nomifensine; Norepinephrine; Propiophenones; Propylamines; Receptors, Neurotransmitter; Serotonin; Trazodone; Zimeldine

1985
The dexamethasone suppression test and antidepressant response in major depression.
    Journal of psychiatric research, 1987, Volume: 21, Issue:3

    Topics: Adolescent; Adult; Aged; Anthracenes; Depressive Disorder; Dexamethasone; Dose-Response Relationship, Drug; Female; Humans; Male; Maprotiline; Middle Aged; Time Factors; Trazodone

1987
Second-generation antidepressants.
    The Psychiatric clinics of North America, 1984, Volume: 7, Issue:3

    Topics: Alprazolam; Amoxapine; Antidepressive Agents; Benzodiazepines; Bupropion; Citalopram; Clinical Trials as Topic; Dopamine; Double-Blind Method; Humans; Maprotiline; Nomifensine; Norepinephrine; Propiophenones; Propylamines; Seizures; Serotonin; Trazodone; Zimeldine

1984
Evaluating the effectiveness of the new antidepressants.
    Hospital & community psychiatry, 1983, Volume: 34, Issue:5

    Topics: Amoxapine; Antidepressive Agents; Clinical Trials as Topic; Depressive Disorder; Humans; Maprotiline; Trazodone; Trimipramine

1983
The efficacy of amoxapine, maprotiline, and trazodone in comparison to imipramine and amitriptyline: a review of the literature.
    Psychopharmacology bulletin, 1984,Spring, Volume: 20, Issue:2

    Topics: Amitriptyline; Amoxapine; Anthracenes; Clinical Trials as Topic; Depression; Dibenzoxazepines; Humans; Imipramine; Maprotiline; Piperazines; Time Factors; Trazodone

1984
Speed of onset of action of the newer antidepressants.
    Psychopharmacology bulletin, 1984,Spring, Volume: 20, Issue:2

    Topics: Amitriptyline; Amoxapine; Antidepressive Agents; Clinical Trials as Topic; Depression; Depressive Disorder; Double-Blind Method; Humans; Imipramine; Maprotiline; Time Factors; Trazodone

1984
[Pharmacologic correction of psycho-emotive disorders in the rehabilitation of patients after removal of brain tumors].
    Voprosy onkologii, 2007, Volume: 53, Issue:6

    Topics: Adult; Alprazolam; Amitriptyline; Anti-Anxiety Agents; Antidepressive Agents; Anxiety; Brain Neoplasms; Depression; Doxepin; Emotions; Female; Humans; Male; Maprotiline; Middle Aged; Moclobemide; Mood Disorders; Neurosurgical Procedures; Nialamide; Sertraline; Thiazepines; Trazodone; Treatment Outcome

2007

Other Studies

28 other study(ies) available for maprotiline and trazodone

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
    Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5

    Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution

2004
Surface activity profiling of drugs applied to the prediction of blood-brain barrier permeability.
    Journal of medicinal chemistry, 2004, Mar-25, Volume: 47, Issue:7

    Topics: Blood-Brain Barrier; Lipid Bilayers; Micelles; Permeability; Pharmaceutical Preparations; Structure-Activity Relationship; Surface Properties

2004
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Relationship between brain tissue partitioning and microemulsion retention factors of CNS drugs.
    Journal of medicinal chemistry, 2009, Mar-26, Volume: 52, Issue:6

    Topics: Brain; Central Nervous System; Chromatography, Liquid; Emulsions; Mass Spectrometry

2009
QSAR-based solubility model for drug-like compounds.
    Bioorganic & medicinal chemistry, 2010, Oct-01, Volume: 18, Issue:19

    Topics: Databases, Factual; Models, Molecular; Pharmaceutical Preparations; Quantitative Structure-Activity Relationship; Solubility; Water

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
    Pharmaceutical research, 2014, Volume: 31, Issue:4

    Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation

2014
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships.
    Bioorganic & medicinal chemistry letters, 2016, 08-15, Volume: 26, Issue:16

    Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone

2016
Marketing 'mind mechanics': decoding antidepressant drug advertisements.
    Social science & medicine (1982), 1986, Volume: 22, Issue:10

    Topics: Advertising; Antidepressive Agents; Communication; Drug Industry; Humans; Maprotiline; Pharmaceutical Services; Physicians; Symbolism; Trazodone

1986
Medications to modify at-home behavior of Alzheimer's patients.
    Geriatrics, 1985, Volume: 40, Issue:12

    Topics: Aged; Alzheimer Disease; Anti-Anxiety Agents; Antidepressive Agents; Antipsychotic Agents; Behavior; Benzodiazepines; Electroconvulsive Therapy; Humans; Lithium; Maprotiline; Middle Aged; Monoamine Oxidase Inhibitors; Nomifensine; Psychotropic Drugs; Trazodone

1985
Relative toxicity of cyclic antidepressants.
    Annals of emergency medicine, 1986, Volume: 15, Issue:7

    Topics: Adolescent; Adult; Aged; Amoxapine; Anthracenes; Antidepressive Agents, Tricyclic; Arrhythmias, Cardiac; Central Nervous System Diseases; Child; Child, Preschool; Coma; Dibenzoxazepines; Female; Humans; Male; Maprotiline; Maryland; Middle Aged; Poison Control Centers; Retrospective Studies; Seizures; Tachycardia; Trazodone

1986
Antidepressant drug therapy: the role of the new antidepressants.
    Hospital & community psychiatry, 1985, Volume: 36, Issue:5

    Topics: Amoxapine; Antidepressive Agents; Bupropion; Cardiovascular Diseases; Depressive Disorder; Drug Evaluation; Humans; Legislation, Drug; Maprotiline; Propiophenones; Trazodone; United States

1985
Acute effects of antidepressants on hippocampal seizures.
    Annals of neurology, 1985, Volume: 18, Issue:6

    Topics: Amitriptyline; Animals; Anticonvulsants; Antidepressive Agents; Bupropion; Desipramine; Epilepsy; Hippocampus; Imipramine; Maprotiline; Propiophenones; Rats; Trazodone

1985
Side effects of the new antidepressants.
    The American journal of psychiatry, 1986, Volume: 143, Issue:2

    Topics: Amoxapine; Anthracenes; Antidepressive Agents; Dibenzoxazepines; Humans; Maprotiline; Trazodone

1986
Update on some of the older and newer antidepressants.
    General hospital psychiatry, 1985, Volume: 7, Issue:2

    Topics: Aged; Amoxapine; Antidepressive Agents; Arrhythmias, Cardiac; Humans; Maprotiline; Parasympathetic Nervous System; Sleep Stages; Trazodone

1985
Antidepressants.
    British medical journal (Clinical research ed.), 1983, Jun-11, Volume: 286, Issue:6381

    Topics: Antidepressive Agents; Antidepressive Agents, Tricyclic; Brompheniramine; Humans; Maprotiline; Mianserin; Nomifensine; Trazodone; Viloxazine; Zimeldine

1983
The newer antidepressant drugs and their cardiovascular effects.
    Psychopharmacology bulletin, 1984,Spring, Volume: 20, Issue:2

    Topics: Amoxapine; Antidepressive Agents; Bupropion; Cardiovascular System; Electrocardiography; Humans; Hypotension, Orthostatic; Maprotiline; Myocardial Contraction; Propiophenones; Trazodone

1984
Adverse reactions, toxicities, and drug interactions of newer antidepressants: anticholinergic, sedative, and other side effects.
    Psychopharmacology bulletin, 1984,Spring, Volume: 20, Issue:2

    Topics: Amoxapine; Antidepressive Agents; Bupropion; Drug Interactions; Humans; Hypnotics and Sedatives; Maprotiline; Parasympatholytics; Propiophenones; Trazodone

1984
[Role and importance of antidepressants in general medicine. Bibliographic review and case contribution].
    Minerva medica, 1984, Aug-25, Volume: 75, Issue:32-33

    Topics: Antidepressive Agents; Family Practice; Humans; Maprotiline; Monoamine Oxidase Inhibitors; Psychophysiologic Disorders; Sulpiride; Trazodone

1984
Three new antidepressants amoxapine, maprotiline, and trazodone.
    Nursing, 1983, Volume: 13, Issue:8

    Topics: Amoxapine; Antidepressive Agents; Depression; Humans; Maprotiline; Trazodone

1983
Recently introduced antidepressants: their place in clinical practice.
    Postgraduate medicine, 1982, Volume: 72, Issue:3

    Topics: Amoxapine; Antidepressive Agents; Bundle of His; Chemical Phenomena; Chemistry; Depressive Disorder; Electrocardiography; Erythema; Heart Rate; Humans; Maprotiline; Trazodone; Tremor; Trimipramine

1982
Mechanism of block of cardiac transient outward K+ current (I(to)) by antidepressant drugs.
    Journal of cardiovascular pharmacology, 1998, Volume: 32, Issue:4

    Topics: Action Potentials; Amitriptyline; Animals; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Binding Sites; Dose-Response Relationship, Drug; Drug Interactions; Heart Ventricles; Imipramine; Maprotiline; Mianserin; Patch-Clamp Techniques; Potassium Channels; Rats; Rats, Wistar; Structure-Activity Relationship; Trazodone; Ventricular Function

1998
Low frequency rTMS as an add-on antidepressive strategy: heterogeneous impact on 99mTc-HMPAO and 18 F-FDG uptake as measured simultaneously with the double isotope SPECT technique. Pilot study.
    Nuclear medicine communications, 2001, Volume: 22, Issue:8

    Topics: Adult; Antidepressive Agents; Brain; Brain Mapping; Citalopram; Depressive Disorder; Female; Fluorodeoxyglucose F18; Functional Laterality; Humans; Magnetics; Male; Maprotiline; Pilot Projects; Radiopharmaceuticals; Reference Values; Technetium Tc 99m Exametazime; Tissue Distribution; Tomography, Emission-Computed, Single-Photon; Trazodone

2001
Simultaneous quantification of citalopram, clozapine, fluoxetine, norfluoxetine, maprotiline, desmethylmaprotiline and trazodone in human serum by HPLC analysis.
    International journal of clinical pharmacology and therapeutics, 2002, Volume: 40, Issue:12

    Topics: Antidepressive Agents, Second-Generation; Antipsychotic Agents; Chromatography, High Pressure Liquid; Citalopram; Clozapine; Fluoxetine; Humans; Maprotiline; Trazodone

2002