maprotiline has been researched along with prazosin in 16 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (12.50) | 18.7374 |
| 1990's | 5 (31.25) | 18.2507 |
| 2000's | 5 (31.25) | 29.6817 |
| 2010's | 4 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Topliss, JG; Yoshida, F | 1 |
| Bacsó, Z; Cianfriglia, M; Fenyvesi, F; Goda, K; Kappelmayer, J; Lustyik, G; Nagy, H; Szabó, G; Szilasi, M | 1 |
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Maj, J; Rogóz, Z; Skuza, G; Sowińska, H | 1 |
| Schultheiss, A; Starke, K; Szabo, B | 1 |
| Mogilnicka, E; Wedzony, K; Zazula, M | 1 |
| Baumann, PA; Hauser, K; Maitre, L; Storni, A; Waldmeier, PC | 1 |
| Auberle, T; Starke, K; Szabo, B | 1 |
| Cai, B; Matsumoto, K; Ohta, H; Watanabe, H | 1 |
| Nörenberg, W; Schöffel, E; Starke, K; Szabo, B | 1 |
| Hajhashemi, V; Minaiyan, M; Movahedian, A; Sadeghi, H; Talebi, A | 1 |
1 review(s) available for maprotiline and prazosin
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
15 other study(ies) available for maprotiline and prazosin
| Article | Year |
|---|---|
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Distinct groups of multidrug resistance modulating agents are distinguished by competition of P-glycoprotein-specific antibodies.
Topics: Adenosine Triphosphatases; Animals; Anti-Bacterial Agents; Antibodies, Monoclonal; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Binding, Competitive; Calcium Channel Blockers; Cyclosporine; Detergents; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Flow Cytometry; Fluoresceins; Humans; Ivermectin; Mice; NIH 3T3 Cells; Substrate Specificity | 2004 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship | 2008 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
The effect of antidepressant drugs on the locomotor hyperactivity induced by MK-801, a non-competitive NMDA receptor antagonist.
Topics: Animals; Antidepressive Agents; Benzazepines; Citalopram; Dizocilpine Maleate; Fluoxetine; Imipramine; Isomerism; Male; Maprotiline; Motor Activity; Prazosin; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Seizures; Sulpiride | 1992 |
The noradrenaline uptake inhibitor, (+)-oxaprotiline, but not the inactive enantiomer, (-)-oxaprotiline, inhibits sympathetic nerve activity in the rabbit: involvement of adrenoceptors.
Topics: Animals; Blood Pressure; Clonidine; Drug Interactions; Ganglia, Sympathetic; Heart Rate; Kidney; Maprotiline; Neurotransmitter Uptake Inhibitors; Norepinephrine; Prazosin; Propranolol; Rabbits; Receptors, Adrenergic, alpha; Stereoisomerism; Sympathetic Nervous System; Yohimbine | 1991 |
Functional supersensitivity to the alpha 1-adrenoceptor agonist after repeated treatment with antidepressant drugs is not conditioned by beta-down-regulation.
Topics: Adrenergic alpha-Agonists; Animals; Antidepressive Agents; Brain Chemistry; Desipramine; Dihydroalprenolol; Male; Maprotiline; Motor Activity; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta | 1987 |
Oxaprotiline, a noradrenaline uptake inhibitor with an active and an inactive enantiomer.
Topics: Animals; Anthracenes; Brain; Electric Stimulation; Female; Maprotiline; Membranes; Molecular Conformation; Myocardium; Norepinephrine; Prazosin; Rats; Serotonin; Stereoisomerism; Synaptosomes; Tyramine | 1982 |
Inhibition of uptake 1 by (+)-oxaprotiline reveals a differential central regulation of noradrenaline and adrenaline release.
Topics: Anesthesia; Animals; Antidepressive Agents; Blood Pressure; Dose-Response Relationship, Drug; Epinephrine; Female; Heart Rate; Kinetics; Male; Maprotiline; Norepinephrine; Prazosin; Rabbits; Receptors, Adrenergic, alpha-2 | 1993 |
Biphasic effects of typical antidepressants and mianserin, an atypical antidepressant, on aggressive behavior in socially isolated mice.
Topics: Aggression; Amitriptyline; Animals; Antidepressive Agents; Brain Chemistry; Clomipramine; Male; Maprotiline; Mianserin; Mice; Mice, Inbred Strains; Motor Activity; Norepinephrine; Prazosin; Receptors, Adrenergic, alpha; Selective Serotonin Reuptake Inhibitors; Social Isolation; Yohimbine | 1993 |
Subtype determination of soma-dendritic alpha2-autoreceptors in slices of rat locus coeruleus.
Topics: Action Potentials; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Autoreceptors; Brimonidine Tartrate; Dendrites; In Vitro Techniques; Locus Coeruleus; Maprotiline; Neurons; Norepinephrine; Phentolamine; Prazosin; Quinoxalines; Rats; Receptors, Adrenergic, alpha; Yohimbine | 1997 |
Central and peripheral anti-inflammatory effects of maprotiline on carrageenan-induced paw edema in rats.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic beta-Antagonists; Animals; Anti-Inflammatory Agents; Antidepressive Agents, Second-Generation; Carrageenan; Edema; Hormone Antagonists; Indomethacin; Injections, Spinal; Male; Maprotiline; Mifepristone; Naloxone; Narcotic Antagonists; Prazosin; Propranolol; Rats; Rats, Wistar; Yohimbine | 2010 |