maprotiline and paroxetine

maprotiline has been researched along with paroxetine in 29 studies

Research

Studies (29)

Timeframe	Studies, this research(%)	All Research%
pre-1990	1 (3.45)	18.7374
1990's	9 (31.03)	18.2507
2000's	9 (31.03)	29.6817
2010's	10 (34.48)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Topliss, JG; Yoshida, F	1
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY	1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL	1
Bleich, S; Gulbins, E; Kornhuber, J; Reichel, M; Terfloth, L; Tripal, P; Wiltfang, J	1
Lombardo, F; Obach, RS; Waters, NJ	1
Ahman, M; Holmén, AG; Wan, H	1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ	1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ	1
Ekins, S; Williams, AJ; Xu, JJ	1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V	1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY	1
Bellman, K; Knegtel, RM; Settimo, L	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Jones, LH; Nadanaciva, S; Rana, P; Will, Y	1
de Vries, J; Deijen, JB; Loriaux, SM; Orlebeke, JF	1
Janne, P; Lejeune, D; Reynaert, C; Vause, M; Zdanowicz, N	1
Andersch, B; Eriksson, E; Hedberg, MA; Sundblad, C	1
Koller-Leiser, A; Schnyder, U	1
Benkert, O; Meister, W; Philipp, M; Staab, HJ; Szegedi, A; Wetzel, H	1
Angersbach, D; Benkert, O; Dunbar, GC; Philipp, M; Schwarze, H; Szegedi, A; Wetzel, H	1
Angersbach, D; Benkert, O; Philipp, M; Szegedi, A; Wetzel, H	1
Gray, AM; Sewell, RD; Spencer, PS	1
Gray, AM; Pache, DM; Sewell, RD	1
Abramson, I; Atkinson, JH; Epping-Jordan, JE; Garfin, SR; Grant, I; Patterson, TL; Pruitt, SD; Slater, MA; Wahlgren, DR; Williams, RA; Zisook, S	1
Antonietti, M; Denis, P; Ducrotte, P; Lalaude, O; Leroi, AM; Menard, JF; Touchais, JY	1
Ikenouchi-Sugita, A; Nakamura, J; Yoshimura, R	1
Farooqui, AA; Lee, LH; Ong, WY; Shui, G; Tan, CH; Wenk, MR	1
Aboukhatwa, MA; Undieh, AS	1
Asakura, M; Fujiwara, K; Kanai, S; Nakano, M; Osada, K; Sasuga, Y; Tanaka, D; Yanagida, T	1

Reviews

2 review(s) available for maprotiline and paroxetine

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
[Review of pharmacological efficacies and side effects of antidepressants]. Nihon rinsho. Japanese journal of clinical medicine, 2007, Volume: 65, Issue:9 Topics: Antidepressive Agents; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Fluvoxamine; Humans; Imipramine; Maprotiline; Paroxetine; Sulpiride; Trazodone	2007

Trials

8 trial(s) available for maprotiline and paroxetine

Article	Year
The effects of paroxetine and maprotiline on mood, perceptual-motor skills, and eye movements in healthy volunteers. Acta psychiatrica Scandinavica. Supplementum, 1989, Volume: 350 Topics: Adult; Affect; Anthracenes; Antidepressive Agents; Clinical Trials as Topic; Double-Blind Method; Eye Movements; Female; Humans; Male; Maprotiline; Paroxetine; Piperidines; Psychomotor Performance; Serotonin Antagonists	1989
Clinical trials of antidepressants: the hidden face: where locus of control appears to play a key role in depression outcome. Psychopharmacology, 1995, Volume: 119, Issue:4 Topics: Adult; Antidepressive Agents; Depression; Fluoxetine; Humans; Internal-External Control; Maprotiline; Paroxetine; Psychiatric Status Rating Scales; Time Factors; Treatment Outcome	1995
The serotonin reuptake inhibitor paroxetin is superior to the noradrenaline reuptake inhibitor maprotiline in the treatment of premenstrual syndrome. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 1995, Volume: 12, Issue:2 Topics: Double-Blind Method; Female; Humans; Maprotiline; Paroxetine; Placebos; Premenstrual Syndrome; Treatment Outcome	1995
A double-blind, multicentre study of paroxetine and maprotiline in major depression. Canadian journal of psychiatry. Revue canadienne de psychiatrie, 1996, Volume: 41, Issue:4 Topics: Adolescent; Adult; Aged; Antidepressive Agents; Depressive Disorder; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Male; Maprotiline; Middle Aged; Paroxetine; Safety	1996
Dose escalation vs. continued doses of paroxetine and maprotiline: a prospective study in depressed out-patients with inadequate treatment response. Acta psychiatrica Scandinavica, 1997, Volume: 95, Issue:4 Topics: Adult; Antidepressive Agents, Second-Generation; Depressive Disorder; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Female; Humans; Male; Maprotiline; Middle Aged; Paroxetine; Personality Inventory; Prospective Studies; Treatment Outcome	1997
A double-blind study comparing paroxetine and maprotiline in depressed outpatients. Pharmacopsychiatry, 1997, Volume: 30, Issue:3 Topics: Adult; Ambulatory Care; Antidepressive Agents, Second-Generation; Depressive Disorder; Double-Blind Method; Female; Humans; Male; Maprotiline; Paroxetine; Psychiatric Status Rating Scales	1997
Response to treatment in minor and major depression: results of a double-blind comparative study with paroxetine and maprotiline. Journal of affective disorders, 1997, Volume: 45, Issue:3 Topics: Adolescent; Adult; Aged; Depressive Disorder; Double-Blind Method; Female; Humans; Male; Maprotiline; Middle Aged; Paroxetine; Personality Inventory; Placebos; Psychiatric Status Rating Scales; Severity of Illness Index; Treatment Outcome; Xerostomia	1997
Effects of noradrenergic and serotonergic antidepressants on chronic low back pain intensity. Pain, 1999, Volume: 83, Issue:2 Topics: Adrenergic Uptake Inhibitors; Adult; Aged; Chronic Disease; Diphenhydramine; Double-Blind Method; Humans; Hypnotics and Sedatives; Low Back Pain; Maprotiline; Middle Aged; Pain Measurement; Paroxetine; Patient Selection; Placebos; Selective Serotonin Reuptake Inhibitors	1999

Other Studies

19 other study(ies) available for maprotiline and paroxetine

Article	Year
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics. Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5 Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution	2004
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling. Current drug discovery technologies, 2004, Volume: 1, Issue:4 Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration	2004
Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model. Journal of medicinal chemistry, 2008, Jan-24, Volume: 51, Issue:2 Topics: Algorithms; Animals; Cell Line; Cell Line, Tumor; Chemical Phenomena; Chemistry, Physical; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Molecular Conformation; Quantitative Structure-Activity Relationship; Rats; Sphingomyelin Phosphodiesterase	2008
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Relationship between brain tissue partitioning and microemulsion retention factors of CNS drugs. Journal of medicinal chemistry, 2009, Mar-26, Volume: 52, Issue:6 Topics: Brain; Central Nervous System; Chromatography, Liquid; Emulsions; Mass Spectrometry	2009
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species. Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6 Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics	2010
Developing structure-activity relationships for the prediction of hepatotoxicity. Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes	2010
A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12 Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands	2010
FDA-approved drug labeling for the study of drug-induced liver injury. Drug discovery today, 2011, Volume: 16, Issue:15-16 Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration	2011
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds. Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10 Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding	2012
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds. Pharmaceutical research, 2014, Volume: 31, Issue:4 Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation	2014
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships. Bioorganic & medicinal chemistry letters, 2016, 08-15, Volume: 26, Issue:16 Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone	2016
The involvement of the opioidergic system in the antinociceptive mechanism of action of antidepressant compounds. British journal of pharmacology, 1998, Volume: 124, Issue:4 Topics: Abdominal Muscles; Acetic Acid; Amitriptyline; Analgesics; Animals; Antidepressive Agents; Cyclobutanes; Dothiepin; Male; Maprotiline; Mice; Muscle Contraction; Naloxone; Naltrexone; Narcotic Antagonists; Neprilysin; Neurotransmitter Uptake Inhibitors; Opioid Peptides; Pain Measurement; Paroxetine; Protease Inhibitors; Receptors, Opioid; Selective Serotonin Reuptake Inhibitors; Thiorphan	1998
Do alpha2-adrenoceptors play an integral role in the antinociceptive mechanism of action of antidepressant compounds? European journal of pharmacology, 1999, Aug-06, Volume: 378, Issue:2 Topics: Adrenergic alpha-Agonists; Adrenergic Uptake Inhibitors; Amitriptyline; Analgesics; Animals; Antidepressive Agents; Cyclobutanes; Dothiepin; Drug Interactions; Male; Maprotiline; Mice; Norepinephrine; Pain Measurement; Paroxetine; Random Allocation; Receptors, Adrenergic; Selective Serotonin Reuptake Inhibitors	1999
Prolonged stationary colonic motility recording in seven patients with severe constipation secondary to antidepressants. Neurogastroenterology and motility, 2000, Volume: 12, Issue:2 Topics: Adult; Amitriptyline; Antidepressive Agents; Anxiety Disorders; Cathartics; Cholinergic Antagonists; Clomipramine; Colon; Colonoscopy; Constipation; Depressive Disorder; Eating; Fecal Impaction; Female; Gastrointestinal Motility; Humans; Male; Manometry; Maprotiline; Middle Aged; Mood Disorders; Muscle Contraction; Paroxetine; Selective Serotonin Reuptake Inhibitors; Thiazepines; Viloxazine	2000
Lipidomic analyses of the mouse brain after antidepressant treatment: evidence for endogenous release of long-chain fatty acids? The international journal of neuropsychopharmacology, 2009, Volume: 12, Issue:7 Topics: Animals; Antidepressive Agents; Basal Ganglia; Brain; Ceramides; Cerebellum; Chromatography, High Pressure Liquid; Fatty Acids; Fluoxetine; Hippocampus; Injections, Intraperitoneal; Lysophospholipids; Male; Maprotiline; Mice; Mice, Inbred BALB C; Paroxetine; Phosphatidylcholines; Phospholipases A2; Prefrontal Cortex; Spectrometry, Mass, Electrospray Ionization; Sphingomyelins; Time Factors	2009
Antidepressant stimulation of CDP-diacylglycerol synthesis does not require monoamine reuptake inhibition. BMC neuroscience, 2010, Jan-27, Volume: 11 Topics: Animals; Antidepressive Agents; Biogenic Monoamines; Cerebral Cortex; Cytidine Diphosphate Diglycerides; Diacylglycerol Cholinephosphotransferase; Dose-Response Relationship, Drug; Hippocampus; Imipramine; Male; Maprotiline; Mice; Mice, Inbred C57BL; Paroxetine; PC12 Cells; Rats; Rats, Sprague-Dawley; Serotonin; Serotonin Plasma Membrane Transport Proteins	2010
[The delayed sensitization of CRH response developed after chronic variable stress on the acoustic startle reflex]. Nihon shinkei seishin yakurigaku zasshi = Japanese journal of psychopharmacology, 2011, Volume: 31, Issue:1 Topics: Animals; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Corticotropin-Releasing Hormone; Desipramine; Male; Maprotiline; Norepinephrine; Paroxetine; Rats; Rats, Wistar; Receptors, Corticotropin; Reflex, Acoustic; Reflex, Startle; Stress, Psychological; Time Factors	2011