maprotiline has been researched along with nortriptyline in 35 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (28.57) | 18.7374 |
| 1990's | 4 (11.43) | 18.2507 |
| 2000's | 9 (25.71) | 29.6817 |
| 2010's | 9 (25.71) | 24.3611 |
| 2020's | 3 (8.57) | 2.80 |
| Authors | Studies |
|---|---|
| Medina-Hernández, MJ; Quiñones-Torrelo, C; Sagrado, S; Villanueva-Camañas, RM | 1 |
| Topliss, JG; Yoshida, F | 1 |
| Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY | 1 |
| Johans, C; Kinnunen, PK; Söderlund, T; Suomalainen, P | 1 |
| Ikeda, K; Kobayashi, T; Washiyama, K | 1 |
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Bleich, S; Gulbins, E; Kornhuber, J; Reichel, M; Terfloth, L; Tripal, P; Wiltfang, J | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Ahman, M; Holmén, AG; Wan, H | 1 |
| Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM | 1 |
| García-Mera, X; González-Díaz, H; Prado-Prado, FJ | 1 |
| Glen, RC; Lowe, R; Mitchell, JB | 1 |
| Gozalbes, R; Pineda-Lucena, A | 1 |
| Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
| Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Bellman, K; Knegtel, RM; Settimo, L | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Jones, LH; Nadanaciva, S; Rana, P; Will, Y | 1 |
| Cardoso, FC; Duggan, PJ; Kuiper, MJ; Lewis, RJ; Schmit, M; Tuck, KL | 1 |
| Brodie, NH; McGhie, RL; O'Hara, H; O'Hara, J; Schiff, AA; Valle-Jones, JC | 1 |
| Gupta, R; Molnar, G; Wallace, J | 1 |
| Connor, JN; Johnson, GF; Solomon, HM | 1 |
| Fukuchi, H; Kimura, M; Kimura, Y; Kitaura, T; Miyake, K; Nakahara, T; Sarai, K | 1 |
| Arita, M; Izumi, F; Takara, H; Wada, A | 1 |
| Iri, H; Kanba, S; Kubo, H; Matsumoto, K; Yagi, G; Yuki, H | 1 |
| Hrdina, PD | 1 |
| Domínguez-Gil, A; Fernández de Gatta, MM; García, MJ; Gutierrez, JR; Tamayo, M | 1 |
| Baumann, P | 1 |
| Giedke, H; Heimann, H; Rein, W | 1 |
| Itoh, M; Nakao, H; Notomi, A; Yufu, N | 1 |
| Baba, A; Hori, T; Kurita, H; Piletz, JE; Sasaki, M; Shiraishi, H; Suzuki, T | 1 |
| Blomgren, B; Dahlin, KL; Lâstbom, L; Ryrfeldt, A | 1 |
| Giles, R; Girard, MFC; Hopfgartner, G; Knight, P | 1 |
| Yamini, Y; Zamani, R | 1 |
1 review(s) available for maprotiline and nortriptyline
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
2 trial(s) available for maprotiline and nortriptyline
| Article | Year |
|---|---|
Maprotiline and fluphenazine/nortriptyline in depression.
Topics: Adult; Aged; Anthracenes; Clinical Trials as Topic; Depression; Double-Blind Method; Drug Therapy, Combination; Female; Fluphenazine; Humans; Male; Maprotiline; Middle Aged; Nortriptyline; Random Allocation | 1978 |
[Changes in slow evoked potentials in depressed patients treated with amitriptyline and oxaprotiline].
Topics: Adult; Amitriptyline; Anthracenes; Antidepressive Agents; Contingent Negative Variation; Depressive Disorder; Double-Blind Method; Electrophysiology; Evoked Potentials, Auditory; Female; Humans; Male; Maprotiline; Middle Aged; Nortriptyline; Random Allocation | 1987 |
32 other study(ies) available for maprotiline and nortriptyline
| Article | Year |
|---|---|
Development of predictive retention-activity relationship models of tricyclic antidepressants by micellar liquid chromatography.
Topics: Adenylyl Cyclase Inhibitors; Adrenergic alpha-Antagonists; Animals; Antidepressive Agents, Tricyclic; Chromatography, Liquid; Enzyme Inhibitors; Histamine H1 Antagonists; Micelles; Models, Biological; Norepinephrine; Rats; Receptors, Adrenergic, alpha-1; Selective Serotonin Reuptake Inhibitors; Serotonin; Structure-Activity Relationship | 1999 |
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution | 2004 |
Surface activity profiling of drugs applied to the prediction of blood-brain barrier permeability.
Topics: Blood-Brain Barrier; Lipid Bilayers; Micelles; Permeability; Pharmaceutical Preparations; Structure-Activity Relationship; Surface Properties | 2004 |
Inhibition of G protein-activated inwardly rectifying K+ channels by various antidepressant drugs.
Topics: Animals; Antidepressive Agents; Antidepressive Agents, Tricyclic; Electrophysiology; Female; G Protein-Coupled Inwardly-Rectifying Potassium Channels; GTP-Binding Proteins; Heart; Humans; Myocardium; Oocytes; Potassium Channel Blockers; Potassium Channels, Inwardly Rectifying; RNA, Messenger; Xenopus laevis | 2004 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model.
Topics: Algorithms; Animals; Cell Line; Cell Line, Tumor; Chemical Phenomena; Chemistry, Physical; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Molecular Conformation; Quantitative Structure-Activity Relationship; Rats; Sphingomyelin Phosphodiesterase | 2008 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Relationship between brain tissue partitioning and microemulsion retention factors of CNS drugs.
Topics: Brain; Central Nervous System; Chromatography, Liquid; Emulsions; Mass Spectrometry | 2009 |
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
Topics: | 2008 |
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics | 2010 |
Predicting phospholipidosis using machine learning.
Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine | 2010 |
QSAR-based solubility model for drug-like compounds.
Topics: Databases, Factual; Models, Molecular; Pharmaceutical Preparations; Quantitative Structure-Activity Relationship; Solubility; Water | 2010 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
FDA-approved drug labeling for the study of drug-induced liver injury.
Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration | 2011 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation | 2014 |
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships.
Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone | 2016 |
Inhibition of N-type calcium ion channels by tricyclic antidepressants - experimental and theoretical justification for their use for neuropathic pain.
Topics: | 2022 |
Guidelines for clinical use in interpreting tricyclic plasma levels.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Depression; Dose-Response Relationship, Drug; Humans; Imipramine; Maprotiline; Nortriptyline | 1979 |
Quantitation of amitriptyline and nortriptyline in human serum.
Topics: Amitriptyline; Chromatography, Gas; Dealkylation; Doxepin; Humans; Maprotiline; Nortriptyline | 1977 |
Association between dosage and serum concentration of antidepressants.
Topics: Adult; Aged; Aging; Amitriptyline; Antidepressive Agents; Biotransformation; Chromatography, High Pressure Liquid; Female; Humans; Male; Maprotiline; Middle Aged; Nortriptyline | 1990 |
Inhibition of 22Na influx by tricyclic and tetracyclic antidepressants and binding of [3H]imipramine in bovine adrenal medullary cells.
Topics: Adrenal Medulla; Amitriptyline; Animals; Anthracenes; Calcium; Carrier Proteins; Catecholamines; Cattle; Cells, Cultured; Imipramine; Kinetics; Maprotiline; Mianserin; Nortriptyline; Receptors, Drug; Receptors, Neurotransmitter; Sodium; Sodium Radioisotopes; Structure-Activity Relationship; Tritium | 1987 |
Automated determination of drugs in serum by column-switching high-performance liquid chromatography. IV. Separation of tricyclic and tetracyclic antidepressants and their metabolites.
Topics: Amitriptyline; Amoxapine; Antidepressive Agents; Antidepressive Agents, Tricyclic; Autoanalysis; Chromatography, High Pressure Liquid; Clomipramine; Humans; Hydrogen-Ion Concentration; Maprotiline; Nortriptyline; Quality Control; Regression Analysis | 1989 |
Regulation of high- and low-affinity [3H]imipramine recognition sites in rat brain by chronic treatment with antidepressants.
Topics: Animals; Antidepressive Agents; Binding, Competitive; Biogenic Amines; Brain; Carrier Proteins; Fluoxetine; In Vitro Techniques; Iprindole; Kinetics; Male; Maprotiline; Nortriptyline; Phenelzine; Rats; Rats, Inbred Strains; Receptors, Drug; Receptors, Neurotransmitter; Serotonin; Synaptosomes | 1987 |
High levels of tricyclic antidepressants in conventional therapy: determinant factors.
Topics: Adult; Aged; Aged, 80 and over; Amitriptyline; Antidepressive Agents, Tricyclic; Clomipramine; Dose-Response Relationship, Drug; Female; Humans; Imipramine; Male; Maprotiline; Middle Aged; Nortriptyline; Risk Factors | 1988 |
New aspects in research on blood levels and bioavailability of antidepressants.
Topics: Amitriptyline; Antidepressive Agents; Biological Availability; Debrisoquin; Depressive Disorder; Humans; Kinetics; Maprotiline; Mephenytoin; Nortriptyline | 1986 |
Simultaneous measurement of various antidepressants in the plasma of depressed patients by high performance liquid chromatography.
Topics: Adult; Amitriptyline; Amoxapine; Antidepressive Agents; Chromatography, High Pressure Liquid; Clomipramine; Depressive Disorder; Desipramine; Dose-Response Relationship, Drug; Female; Humans; Imipramine; Male; Maprotiline; Middle Aged; Nortriptyline | 1984 |
The Pisa syndrome (pleurothotonus) during antidepressant therapy.
Topics: Amitriptyline; Antidepressive Agents; Biperiden; Depressive Disorder; Dose-Response Relationship, Drug; Drug Therapy, Combination; Dyskinesia, Drug-Induced; Humans; Imipramine; Male; Maprotiline; Middle Aged; Nortriptyline; Orientation; Postural Balance; Posture | 1997 |
Acute lung failure induced by tricyclic antidepressants.
Topics: Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Desipramine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Overdose; Imipramine; Lung; Maprotiline; Mianserin; Microscopy, Electron; Nortriptyline; Organ Size; Perfusion; Pulmonary Edema; Pulmonary Ventilation; Rats; Rats, Sprague-Dawley | 1997 |
Effects of the LC mobile phase in vacuum differential mobility spectrometry-mass spectrometry for the selective analysis of antidepressant drugs in human plasma.
Topics: Acetonitriles; Amitriptyline; Antidepressive Agents; Desipramine; Humans; Imipramine; Maprotiline; Mass Spectrometry; Methanol; Nortriptyline; Reproducibility of Results; Spectrum Analysis; Vacuum; Venlafaxine Hydrochloride | 2022 |
On-Chip Electromembrane Surrounded Solid Phase Microextraction for Determination of Tricyclic Antidepressants from Biological Fluids Using Poly(3,4-ethylenedioxythiophene)-Graphene Oxide Nanocomposite as a Fiber Coating.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Desipramine; Humans; Imipramine; Limit of Detection; Maprotiline; Nanocomposites; Nortriptyline; Reproducibility of Results; Sertraline; Solid Phase Microextraction | 2023 |