maprotiline and fluvoxamine

maprotiline has been researched along with fluvoxamine in 37 studies

Research

Studies (37)

TimeframeStudies, this research(%)All Research%
pre-19906 (16.22)18.7374
1990's15 (40.54)18.2507
2000's9 (24.32)29.6817
2010's7 (18.92)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Adkison, KK; Humphreys, JE; Mahar Doan, KM; Polli, JW; Serabjit-Singh, CJ; Shampine, LJ; Webster, LO; Wring, SA1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Glen, RC; Lowe, R; Mitchell, JB1
Ekins, S; Williams, AJ; Xu, JJ1
Fijorek, K; Glinka, A; Mendyk, A; Polak, S; Wiśniowska, B1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Danos, P; Höflich, G; Kasper, S; Schmidt, R1
Deanović, Z; Jakovljević, M; Mück-Seler, D1
Kasper, S; Kick, H; Vieira, A; Voll, G2
de Jonghe, F; Swinkels, J; Tuynman-Qua, H1
Den Boer, JA; Westenberg, HG1
Berger, M; Emrich, HM; Riemann, D; von Zerssen, D1
Blansjaar, BA; Dijken, WA; Haffmans, J; Kamp, JS; Kramer, HJ; Nolen, WA; van de Putte, JJ2
Dijken, WA; Kamp, JS; Nolen, WA; van de Putte, JJ1
Bradford, D; Krijzer, F; Snelder, M1
De Leeuw, AS; den Boer, JA; van Vliet, IM; Westenberg, HG1
Obergfell, A; Starke, K; Szabo, B1
Dratcu, L; Keating, J; Lader, M; Sherwood, RA1
Dötsch, M; Kasper, S; Kick, H; Möller, HJ; Vieira, A1
Hashimoto, S; Inoue, T; Koyama, T1
Gattaz, WF; Hewer, W; Rost, W1
Bourin, M; Redrobe, JP1
Lopukhov, IG1
Shmugliakov, N; Silver, H1
Inoue, K; Sugimoto, Y; Yamada, J1
Hashimoto, S; Hattori, T; Kawasaki, K; Kitamura, Y; Miki, N; Mochizuki, D; Otsuka, Y; Tsujita, R; Yamada, S1
Kanba, S; Miyaoka, H; Nakaki, T; Shintani, F; Suzuki, E1
Sugimoto, Y; Yamada, J1
Bubl, B; Feuerstein, TJ; Hubbe, U; Huethe, F; Jackisch, R; Löffler, M; McIntosh, JM1
Ikenouchi-Sugita, A; Nakamura, J; Yoshimura, R1
Amin, B; Hajhashemi, V1

Reviews

2 review(s) available for maprotiline and fluvoxamine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
[Review of pharmacological efficacies and side effects of antidepressants].
    Nihon rinsho. Japanese journal of clinical medicine, 2007, Volume: 65, Issue:9

    Topics: Antidepressive Agents; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Fluvoxamine; Humans; Imipramine; Maprotiline; Paroxetine; Sulpiride; Trazodone

2007

Trials

14 trial(s) available for maprotiline and fluvoxamine

ArticleYear
Thyroid hormones, body temperature, and antidepressant treatment.
    Biological psychiatry, 1992, Apr-15, Volume: 31, Issue:8

    Topics: Adult; Aged; Body Temperature; Depressive Disorder; Double-Blind Method; Female; Fluvoxamine; Humans; Male; Maprotiline; Middle Aged; Psychiatric Status Rating Scales; Thyroid Hormones

1992
Effect of antidepressant treatment on platelet 5-HT content and relation to therapeutic outcome in unipolar depressive patients.
    Journal of affective disorders, 1991, Volume: 23, Issue:3

    Topics: Adult; Aged; Amitriptyline; Antidepressive Agents; Blood Platelets; Depressive Disorder; Double-Blind Method; Female; Fluvoxamine; Humans; Male; Maprotiline; Middle Aged; Oximes; Psychiatric Status Rating Scales; Serotonin; Trazodone

1991
Therapeutic sleep deprivation and antidepressant medication in patients with major depression.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 1991, Volume: 1, Issue:2

    Topics: Antidepressive Agents; Combined Modality Therapy; Depressive Disorder; Double-Blind Method; Fluvoxamine; Humans; Maprotiline; Psychiatric Status Rating Scales; Sleep Deprivation

1991
Randomized double-blind study of fluvoxamine and maprotiline in treatment of depression.
    Pharmacopsychiatry, 1991, Volume: 24, Issue:1

    Topics: Adolescent; Adult; Antidepressive Agents; Depression; Double-Blind Method; Female; Fluvoxamine; Humans; Male; Maprotiline; Middle Aged; Oximes; Psychiatric Status Rating Scales

1991
Response to total sleep deprivation before and during treatment with fluvoxamine or maprotiline in patients with major depression--results of a double-blind study.
    Pharmacopsychiatry, 1990, Volume: 23, Issue:3

    Topics: Adult; Aged; Anthracenes; Depressive Disorder; Double-Blind Method; Female; Fluvoxamine; Heart Rate; Humans; Male; Maprotiline; Middle Aged; Oximes; Psychiatric Status Rating Scales; Randomized Controlled Trials as Topic; Sleep Deprivation

1990
Effect of a serotonin and noradrenaline uptake inhibitor in panic disorder; a double-blind comparative study with fluvoxamine and maprotiline.
    International clinical psychopharmacology, 1988, Volume: 3, Issue:1

    Topics: Adult; Agoraphobia; Anthracenes; Anxiety Disorders; Brain; Clinical Trials as Topic; Depressive Disorder; Double-Blind Method; Fear; Female; Fluvoxamine; Humans; Male; Maprotiline; Oximes; Panic; Phobic Disorders; Psychological Tests; Receptors, Adrenergic; Receptors, Serotonin; Serotonin Antagonists

1988
Serotonin reuptake inhibition vs. norepinephrine reuptake inhibition: a double-blind differential-therapeutic study with fluvoxamine and oxaprotiline in endogenous and neurotic depressives.
    Pharmacopsychiatry, 1987, Volume: 20, Issue:2

    Topics: Adult; Aged; Anthracenes; Antidepressive Agents; Depressive Disorder; Dexamethasone; Female; Fluvoxamine; Humans; Hydrocortisone; Male; Maprotiline; Middle Aged; Norepinephrine; Oximes; Prognosis; Psychiatric Status Rating Scales; Serotonin

1987
Treatment strategy in depression. I. Non-tricyclic and selective reuptake inhibitors in resistant depression: a double-blind partial crossover study on the effects of oxaprotiline and fluvoxamine.
    Acta psychiatrica Scandinavica, 1988, Volume: 78, Issue:6

    Topics: Adult; Anthracenes; Bipolar Disorder; Depressive Disorder; Double-Blind Method; Female; Fluvoxamine; Humans; Male; Maprotiline; Middle Aged; Oximes; Personality Disorders; Psychological Tests; Psychometrics

1988
Treatment strategy in depression. II. MAO inhibitors in depression resistant to cyclic antidepressants: two controlled crossover studies with tranylcypromine versus L-5-hydroxytryptophan and nomifensine.
    Acta psychiatrica Scandinavica, 1988, Volume: 78, Issue:6

    Topics: 5-Hydroxytryptophan; Adult; Aged; Clinical Trials as Topic; Depressive Disorder; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Drug Resistance; Female; Fluvoxamine; Humans; Male; Maprotiline; Middle Aged; Nomifensine; Oximes; Psychological Tests; Tranylcypromine

1988
L-5HTP in depression resistant to re-uptake inhibitors. An open comparative study with tranylcypromine.
    The British journal of psychiatry : the journal of mental science, 1985, Volume: 147

    Topics: 5-Hydroxytryptophan; Adult; Aged; Carbidopa; Clinical Trials as Topic; Depressive Disorder; Drug Resistance; Drug Therapy, Combination; Fluvoxamine; Follow-Up Studies; Humans; Maprotiline; Middle Aged; Oximes; Random Allocation; Serotonin Antagonists; Stereoisomerism; Tranylcypromine

1985
Measurement of plasma serotonin by high-performance liquid chromatography with electrochemical detection as an index of the in vivo activity of fluvoxamine.
    Journal of chromatography, 1993, Jun-02, Volume: 615, Issue:2

    Topics: Adult; Chromatography, High Pressure Liquid; Electrochemistry; Female; Fluvoxamine; Humans; Indicators and Reagents; Male; Maprotiline; Serotonin

1993
Plasma concentrations of fluvoxamine and maprotiline in major depression: implications on therapeutic efficacy and side effects.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 1993, Volume: 3, Issue:1

    Topics: Adult; Analysis of Variance; Depressive Disorder; Double-Blind Method; Female; Fluvoxamine; Humans; Male; Maprotiline; Middle Aged; Psychiatric Status Rating Scales

1993
Cardiovascular effects of fluvoxamine and maprotiline in depressed patients.
    European archives of psychiatry and clinical neuroscience, 1995, Volume: 246, Issue:1

    Topics: Adult; Aged; Antidepressive Agents, Second-Generation; Blood Pressure; Depressive Disorder; Double-Blind Method; Electrocardiography; Female; Fluvoxamine; Heart Rate; Hemodynamics; Humans; Male; Maprotiline; Middle Aged

1995
Augmentation with fluvoxamine but not maprotiline improves negative symptoms in treated schizophrenia: evidence for a specific serotonergic effect from a double-blind study.
    Journal of clinical psychopharmacology, 1998, Volume: 18, Issue:3

    Topics: Adult; Antidepressive Agents; Double-Blind Method; Female; Fluvoxamine; Humans; Male; Maprotiline; Middle Aged; Psychiatric Status Rating Scales; Receptors, Serotonin; Schizophrenia; Selective Serotonin Reuptake Inhibitors

1998

Other Studies

21 other study(ies) available for maprotiline and fluvoxamine

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Passive permeability and P-glycoprotein-mediated efflux differentiate central nervous system (CNS) and non-CNS marketed drugs.
    The Journal of pharmacology and experimental therapeutics, 2002, Volume: 303, Issue:3

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blood-Brain Barrier; Cell Line; Cell Membrane Permeability; Central Nervous System Agents; Dogs; Drug Delivery Systems; Permeability; Pharmaceutical Preparations

2002
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
Predicting phospholipidosis using machine learning.
    Molecular pharmaceutics, 2010, Oct-04, Volume: 7, Issue:5

    Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Predictive model for L-type channel inhibition: multichannel block in QT prolongation risk assessment.
    Journal of applied toxicology : JAT, 2012, Volume: 32, Issue:10

    Topics: Artificial Intelligence; Calcium Channel Blockers; Calcium Channels, L-Type; Cell Line; Computational Biology; Computer Simulation; Drugs, Investigational; Ether-A-Go-Go Potassium Channels; Expert Systems; Heart Rate; Humans; Models, Biological; Myocytes, Cardiac; NAV1.5 Voltage-Gated Sodium Channel; Potassium Channel Blockers; Quantitative Structure-Activity Relationship; Risk Assessment; Shaker Superfamily of Potassium Channels; Torsades de Pointes; Voltage-Gated Sodium Channel Blockers

2012
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
Comparison of the (pro)convulsive properties of fluvoxamine and clovoxamine with eight other antidepressants in an animal model.
    Neuropsychobiology, 1984, Volume: 12, Issue:4

    Topics: Amitriptyline; Animals; Antidepressive Agents; Desipramine; Disease Models, Animal; Dose-Response Relationship, Drug; Electroencephalography; Epilepsy; Fluvoxamine; Imipramine; Male; Maprotiline; Mianserin; Oximes; Rats; Rats, Inbred Strains; Seizures; Viloxazine

1984
Biological dissection of anxiety disorders: the clinical role of selective serotonin reuptake inhibitors with particular reference to fluvoxamine.
    International clinical psychopharmacology, 1995, Volume: 9 Suppl 4

    Topics: Anxiety Disorders; Fluvoxamine; Humans; Maprotiline; Obsessive-Compulsive Disorder; Panic; Receptors, Serotonin; Ritanserin; Selective Serotonin Reuptake Inhibitors; Time Factors

1995
Involvement of monoamine uptake inhibition and local anesthesia in the cardiovascular response to cocaine in conscious rabbits.
    The Journal of pharmacology and experimental therapeutics, 1995, Volume: 273, Issue:1

    Topics: Anesthetics, Local; Animals; Blood Pressure; Cocaine; Electric Stimulation; Fluvoxamine; Heart Rate; Lidocaine; Maprotiline; Procaine; Rabbits; Sympathetic Nervous System

1995
Serotonin reuptake inhibitors reduce conditioned fear stress-induced freezing behavior in rats.
    Psychopharmacology, 1996, Volume: 123, Issue:2

    Topics: Animals; Behavior, Animal; Citalopram; Dose-Response Relationship, Drug; Fear; Fluvoxamine; Male; Maprotiline; Motor Activity; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors

1996
Partial role of 5-HT2 and 5-HT3 receptors in the activity of antidepressants in the mouse forced swimming test.
    European journal of pharmacology, 1997, May-01, Volume: 325, Issue:2-3

    Topics: Amphetamines; Animals; Antidepressive Agents; Behavior, Animal; Citalopram; Desipramine; Drug Interactions; Fluoxetine; Fluvoxamine; Imipramine; Ketanserin; Male; Maprotiline; Mice; Ondansetron; Receptors, Serotonin; Receptors, Serotonin, 5-HT3; Ritanserin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Swimming

1997
[A comparative clinical evaluation of the antidepressive activity of fluoxetine and fluvoxamine].
    Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova, 1997, Volume: 97, Issue:4

    Topics: Adolescent; Adult; Amitriptyline; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Depressive Disorder; Drug Evaluation; Female; Fluoxetine; Fluvoxamine; Humans; Male; Maprotiline; Middle Aged; Time Factors

1997
Selective serotonin reuptake inhibitors fluoxetine and fluvoxamine induce hyperglycemia by different mechanisms.
    European journal of pharmacology, 1999, Oct-15, Volume: 382, Issue:3

    Topics: Animals; Blood Glucose; Enzyme Inhibitors; Fenclonine; Fluoxetine; Fluvoxamine; Hyperglycemia; Insulin; Male; Maprotiline; Mice; Selective Serotonin Reuptake Inhibitors; Time Factors

1999
Neurochemical and behavioural characterization of milnacipran, a serotonin and noradrenaline reuptake inhibitor in rats.
    Psychopharmacology, 2002, Volume: 162, Issue:3

    Topics: Adrenergic Uptake Inhibitors; Analysis of Variance; Animals; Behavior, Animal; Binding, Competitive; Brain Chemistry; Conditioning, Psychological; Cyclopropanes; Dose-Response Relationship, Drug; Fear; Fluoxetine; Fluvoxamine; Imipramine; Male; Maprotiline; Microdialysis; Milnacipran; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Norepinephrine; Prefrontal Cortex; Radioligand Assay; Rats; Rats, Sprague-Dawley; Rats, Wistar; Receptors, Cell Surface; Receptors, Serotonin; Selective Serotonin Reuptake Inhibitors; Serotonin; Swimming; Synaptosomes; Time Factors

2002
Antipsychotic, antidepressant, anxiolytic, and anticonvulsant drugs induce type II nitric oxide synthase mRNA in rat brain.
    Neuroscience letters, 2002, Nov-29, Volume: 333, Issue:3

    Topics: Animals; Anticonvulsants; Antidepressive Agents; Antipsychotic Agents; Brain; Carbamazepine; Chlorpromazine; Diazepam; Fluvoxamine; Gene Expression; Haloperidol; Isoxazoles; Lithium; Male; Maprotiline; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Time Factors; Zonisamide

2002
Differential effects of the 5-HT2 receptor antagonist on the anti-immobility effects of noradrenaline and serotonin reuptake inhibitors in the forced swimming test.
    Brain research, 2002, Dec-20, Volume: 958, Issue:1

    Topics: Adrenergic Uptake Inhibitors; Animals; Brain; Clomipramine; Depressive Disorder; Dose-Response Relationship, Drug; Drug Interactions; Ergolines; Fluoxetine; Fluvoxamine; Male; Maprotiline; Mice; Motor Activity; Neurons; Norepinephrine; Receptors, Serotonin; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Antagonists; Synaptic Transmission

2002
Dopamine release in human neocortical slices: characterization of inhibitory autoreceptors and of nicotinic acetylcholine receptor-evoked release.
    Brain research bulletin, 2006, Jan-30, Volume: 68, Issue:5

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Adolescent; Adult; Aged; Alkaloids; Analysis of Variance; Animals; Autoreceptors; Azocines; Calcium; Child; Child, Preschool; Domperidone; Dopamine; Dopamine Antagonists; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; Feedback; Female; Fluvoxamine; Humans; In Vitro Techniques; Isoxazoles; Male; Maprotiline; Mice; Middle Aged; Neocortex; Nicotine; Nicotinic Antagonists; Potassium; Pyrrolidines; Quinolizines; Rats; Receptors, Nicotinic; Sulpiride; Time Factors; Tritium

2006
Effect of glibenclamide on antinociceptive effects of antidepressants of different classes.
    Clinics (Sao Paulo, Brazil), 2011, Volume: 66, Issue:2

    Topics: Amitriptyline; Analgesics; Analysis of Variance; Animals; Antidepressive Agents; Drug Interactions; Fluvoxamine; Glyburide; Male; Maprotiline; Mice; Models, Animal; Pain; Pain Measurement; Potassium Channel Blockers; Potassium Channels; Random Allocation

2011