maprotiline and doxepin

maprotiline has been researched along with doxepin in 20 studies

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-19907 (35.00)18.7374
1990's2 (10.00)18.2507
2000's8 (40.00)29.6817
2010's3 (15.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Medina-Hernández, MJ; Quiñones-Torrelo, C; Sagrado, S; Villanueva-Camañas, RM1
Topliss, JG; Yoshida, F1
Adkison, KK; Humphreys, JE; Mahar Doan, KM; Polli, JW; Serabjit-Singh, CJ; Shampine, LJ; Webster, LO; Wring, SA1
Johans, C; Kinnunen, PK; Söderlund, T; Suomalainen, P1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Bleich, S; Gulbins, E; Kornhuber, J; Reichel, M; Terfloth, L; Tripal, P; Wiltfang, J1
Lombardo, F; Obach, RS; Waters, NJ1
Ahman, M; Holmén, AG; Wan, H1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Allam, M; Elwan, O; Hassan, MA; Taher, Y1
Heikkilä, L; Kontiainen, H; Malinen, L; Meriläinen, V; Naarala, M; Väisänen, E1
Huey, LY; Janowsky, DS; Risch, SC1
Connor, JN; Johnson, GF; Solomon, HM1
Bakish, D; Browne, M; Horn, E; Hrdina, PD; Lapierre, YD1
Ahles, S; Gwirtsman, H; Halaris, A; Hill, MA; Schwarcz, G; Shah, P1
Ahles, S; DeMet, E; Gwirtsman, HE; Halaris, A; Hill, MA1
Beauchamp, G; Elie, R; Lavoie, PA1
Koval'chuk, VV1

Reviews

1 review(s) available for maprotiline and doxepin

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

6 trial(s) available for maprotiline and doxepin

ArticleYear
A comparative study of antidepressants in the treatment of depressive states.
    The Journal of international medical research, 1976, Volume: 4, Issue:3

    Topics: Adult; Aged; Amitriptyline; Antidepressive Agents; Depression; Dibenzazepines; Dibenzocycloheptenes; Doxepin; Female; Humans; Male; Maprotiline; Middle Aged; Nialamide; Psychiatric Status Rating Scales; Sleep Initiation and Maintenance Disorders

1976
Maprotiline and doxepin in the treatment of depression. A double-glind multicentre comparison.
    Acta psychiatrica Scandinavica, 1978, Volume: 57, Issue:3

    Topics: Adjustment Disorders; Adult; Affective Disorders, Psychotic; Anthracenes; Clinical Trials as Topic; Depression; Double-Blind Method; Doxepin; Drug Evaluation; Female; Humans; Male; Maprotiline; Middle Aged

1978
Antidepressant plasma levels and clinical response in depressed patients treated with oxaprotiline and doxepin.
    International clinical psychopharmacology, 1988, Volume: 3, Issue:3

    Topics: Adult; Antidepressive Agents; Depressive Disorder; Doxepin; Female; Humans; Male; Maprotiline; Middle Aged; Psychiatric Status Rating Scales

1988
Comparative cardiac effects of maprotiline and doxepin in elderly depressed patients.
    The Journal of clinical psychiatry, 1984, Volume: 45, Issue:11

    Topics: Aged; Angina Pectoris; Anthracenes; Blood Pressure; Cardiac Complexes, Premature; Clinical Trials as Topic; Depressive Disorder; Double-Blind Method; Doxepin; Electrocardiography; Female; Heart; Heart Conduction System; Heart Rate; Humans; Male; Maprotiline; Middle Aged; Monitoring, Physiologic; Myocardial Infarction; Posture

1984
Therapeutic superiority of maprotiline versus doxepin in geriatric depression.
    The Journal of clinical psychiatry, 1983, Volume: 44, Issue:12

    Topics: Anthracenes; Clinical Trials as Topic; Constipation; Depressive Disorder; Dizziness; Double-Blind Method; Doxepin; Female; Humans; Male; Maprotiline; Middle Aged; Personality Inventory; Psychiatric Status Rating Scales; Sleep Stages; Xerostomia

1983
[Pharmacologic correction of psycho-emotive disorders in the rehabilitation of patients after removal of brain tumors].
    Voprosy onkologii, 2007, Volume: 53, Issue:6

    Topics: Adult; Alprazolam; Amitriptyline; Anti-Anxiety Agents; Antidepressive Agents; Anxiety; Brain Neoplasms; Depression; Doxepin; Emotions; Female; Humans; Male; Maprotiline; Middle Aged; Moclobemide; Mood Disorders; Neurosurgical Procedures; Nialamide; Sertraline; Thiazepines; Trazodone; Treatment Outcome

2007

Other Studies

13 other study(ies) available for maprotiline and doxepin

ArticleYear
Development of predictive retention-activity relationship models of tricyclic antidepressants by micellar liquid chromatography.
    Journal of medicinal chemistry, 1999, Aug-12, Volume: 42, Issue:16

    Topics: Adenylyl Cyclase Inhibitors; Adrenergic alpha-Antagonists; Animals; Antidepressive Agents, Tricyclic; Chromatography, Liquid; Enzyme Inhibitors; Histamine H1 Antagonists; Micelles; Models, Biological; Norepinephrine; Rats; Receptors, Adrenergic, alpha-1; Selective Serotonin Reuptake Inhibitors; Serotonin; Structure-Activity Relationship

1999
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Passive permeability and P-glycoprotein-mediated efflux differentiate central nervous system (CNS) and non-CNS marketed drugs.
    The Journal of pharmacology and experimental therapeutics, 2002, Volume: 303, Issue:3

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blood-Brain Barrier; Cell Line; Cell Membrane Permeability; Central Nervous System Agents; Dogs; Drug Delivery Systems; Permeability; Pharmaceutical Preparations

2002
Surface activity profiling of drugs applied to the prediction of blood-brain barrier permeability.
    Journal of medicinal chemistry, 2004, Mar-25, Volume: 47, Issue:7

    Topics: Blood-Brain Barrier; Lipid Bilayers; Micelles; Permeability; Pharmaceutical Preparations; Structure-Activity Relationship; Surface Properties

2004
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model.
    Journal of medicinal chemistry, 2008, Jan-24, Volume: 51, Issue:2

    Topics: Algorithms; Animals; Cell Line; Cell Line, Tumor; Chemical Phenomena; Chemistry, Physical; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Molecular Conformation; Quantitative Structure-Activity Relationship; Rats; Sphingomyelin Phosphodiesterase

2008
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Relationship between brain tissue partitioning and microemulsion retention factors of CNS drugs.
    Journal of medicinal chemistry, 2009, Mar-26, Volume: 52, Issue:6

    Topics: Brain; Central Nervous System; Chromatography, Liquid; Emulsions; Mass Spectrometry

2009
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Plasma levels of tricyclic antidepressants and clinical efficacy: review of the literature -- part II.
    The Journal of clinical psychiatry, 1979, Volume: 40, Issue:2

    Topics: Antidepressive Agents, Tricyclic; Biotransformation; Clomipramine; Depression; Desipramine; Dibenzocycloheptenes; Dose-Response Relationship, Drug; Doxepin; Drug Interactions; Humans; Imipramine; Maprotiline; Protriptyline

1979
Quantitation of amitriptyline and nortriptyline in human serum.
    Journal of chromatography, 1977, Jul-01, Volume: 143, Issue:4

    Topics: Amitriptyline; Chromatography, Gas; Dealkylation; Doxepin; Humans; Maprotiline; Nortriptyline

1977
Effect of some stereoisomeric tricyclic antidepressants on 45Ca uptake in synaptosomes from rat hippocampus.
    Psychopharmacology, 1993, Volume: 110, Issue:1-2

    Topics: Animals; Antidepressive Agents; Antidepressive Agents, Tricyclic; Calcium; Calcium Channels; Calcium Radioisotopes; Doxepin; Hippocampus; In Vitro Techniques; Male; Maprotiline; Rats; Rats, Sprague-Dawley; Sodium; Stereoisomerism; Synaptosomes; Trimipramine

1993