maprotiline and desmethylmaprotiline

maprotiline has been researched along with desmethylmaprotiline in 15 studies

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19909 (60.00)18.7374
1990's4 (26.67)18.2507
2000's1 (6.67)29.6817
2010's1 (6.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Berger, ML; Rebernik, P1
Fukuchi, H; Kimura, M; Kimura, Y; Kitaura, T; Miyake, K1
Fukuchi, H; Kimura, M; Kimura, Y; Kitaura, T; Miyake, K; Nakahara, T1
Hrdina, PD; Lapierre, YD1
Baker, GB; Dewhurst, WG; Drebit, R1
Baumann, P; Bosshart, P; Gabris, G; Gastpar, M; Koeb, L; Woggon, B1
Hasegawa, M; Inoue, M; Kido, H; Kurata, K; Yamaguchi, N2
Itoh, M; Nakao, H; Notomi, A; Yufu, N1
Iwai, H; Kubo, S; Kuyama, C; Watanabe, S; Yokoyama, S1
Jindal, SP; Lutz, T; Vestergaard, P1
Richard, A; Sioufi, A1
Kuss, HJ; Sirch, S; Zhao, DY1
Keller, T; Zollinger, U1
Conca, A; Hubmann, MR; König, P; Moll, W; Waschgler, R1

Trials

1 trial(s) available for maprotiline and desmethylmaprotiline

ArticleYear
Relationship between blood concentrations and clinical effects of a new antidepressant "maprotiline".
    Folia psychiatrica et neurologica japonica, 1980, Volume: 34, Issue:2

    Topics: Adult; Anthracenes; Clinical Trials as Topic; Depressive Disorder; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Male; Maprotiline; Middle Aged

1980

Other Studies

14 other study(ies) available for maprotiline and desmethylmaprotiline

ArticleYear
Differential influence of 7 cations on 16 non-competitive NMDA receptor blockers.
    Bioorganic & medicinal chemistry letters, 2015, Oct-01, Volume: 25, Issue:19

    Topics: Animals; Brain; Cations; Diamines; Dizocilpine Maleate; Dose-Response Relationship, Drug; Molecular Structure; Rats; Receptors, N-Methyl-D-Aspartate; Structure-Activity Relationship

2015
Pharmacokinetic analysis of maprotiline and its demethylated metabolite in serum and brain of rats after acute and chronic oral administration of maprotiline.
    Journal of pharmaceutical sciences, 1992, Volume: 81, Issue:10

    Topics: Administration, Oral; Animals; Brain; Drug Administration Schedule; Injections, Intravenous; Male; Maprotiline; Mathematical Computing; Models, Biological; Rats; Rats, Sprague-Dawley; Time Factors

1992
Pharmacokinetics of maprotiline and its demethylated metabolite in serum and specific brain regions of rats after acute and chronic administration of maprotiline.
    Journal of pharmaceutical sciences, 1991, Volume: 80, Issue:12

    Topics: Animals; Brain; Dose-Response Relationship, Drug; Male; Maprotiline; Rats; Rats, Inbred Strains; Time Factors

1991
Plasma levels of maprotiline and zimelidine and their relationship to clinical response in depressed patients.
    Therapeutic drug monitoring, 1986, Volume: 8, Issue:4

    Topics: Anthracenes; Chromatography, Gas; Depressive Disorder; Humans; Maprotiline; Psychiatric Status Rating Scales; Zimeldine

1986
Determination of maprotiline and desmethylmaprotiline in plasma and urine by gas chromatography with nitrogen-phosphorus detection.
    Journal of chromatography, 1988, Nov-18, Volume: 432

    Topics: Adult; Anthracenes; Chromatography, Gas; Depressive Disorder; Female; Humans; Indicators and Reagents; Male; Maprotiline; Middle Aged; Psychiatric Status Rating Scales

1988
Acetylation of maprotiline and desmethylmaprotiline in depressive patients phenotyped with sulfamidine, debrisoquine, and mephenytoin.
    Arzneimittel-Forschung, 1988, Volume: 38, Issue:2

    Topics: Acetylation; Anthracenes; Debrisoquin; Depressive Disorder; Gas Chromatography-Mass Spectrometry; Humans; Maprotiline; Mephenytoin; Phenotype; Sulfamethazine

1988
Serum levels of maprotiline and its adverse effects on depressed patients.
    The Japanese journal of psychiatry and neurology, 1987, Volume: 41, Issue:2

    Topics: Adult; Anthracenes; Antidepressive Agents, Tricyclic; Depressive Disorder; Dose-Response Relationship, Drug; Electroencephalography; Female; Humans; Male; Maprotiline; Middle Aged

1987
A comparison of maprotiline and its desmethylated metabolite serum concentrations in outpatients and inpatients.
    The Japanese journal of psychiatry and neurology, 1987, Volume: 41, Issue:2

    Topics: Adult; Ambulatory Care; Anthracenes; Depressive Disorder; Dose-Response Relationship, Drug; Female; Hospitalization; Humans; Male; Maprotiline; Middle Aged; Patient Compliance

1987
Simultaneous measurement of various antidepressants in the plasma of depressed patients by high performance liquid chromatography.
    Folia psychiatrica et neurologica japonica, 1984, Volume: 38, Issue:1

    Topics: Adult; Amitriptyline; Amoxapine; Antidepressive Agents; Chromatography, High Pressure Liquid; Clomipramine; Depressive Disorder; Desipramine; Dose-Response Relationship, Drug; Female; Humans; Imipramine; Male; Maprotiline; Middle Aged; Nortriptyline

1984
GLC-mass spectrometric determination of maprotiline and its major metabolite using stable isotope-labeled analog as internal standard.
    Journal of pharmaceutical sciences, 1980, Volume: 69, Issue:6

    Topics: Animals; Anthracenes; Gas Chromatography-Mass Spectrometry; Humans; Kinetics; Maprotiline; Methods; Rabbits; Reference Standards

1980
Gas chromatographic determination of maprotiline and its N-desmethyl metabolite in human blood using nitrogen detection.
    Journal of chromatography, 1980, Dec-12, Volume: 221, Issue:2

    Topics: Anthracenes; Chromatography, Gas; Humans; Maprotiline

1980
Assay for maprotiline in human serum with improved sensitivity and selectivity.
    Journal of chromatography. B, Biomedical applications, 1994, Jun-03, Volume: 656, Issue:1

    Topics: Half-Life; Humans; Indicators and Reagents; Maprotiline; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Ultrafiltration

1994
Gas chromatographic examination of postmortem specimens after maprotiline intoxication.
    Forensic science international, 1997, Aug-04, Volume: 88, Issue:2

    Topics: Antidepressive Agents, Second-Generation; Body Fluids; Female; Gas Chromatography-Mass Spectrometry; Humans; Maprotiline; Middle Aged; Poisoning; Suicide

1997
Simultaneous quantification of citalopram, clozapine, fluoxetine, norfluoxetine, maprotiline, desmethylmaprotiline and trazodone in human serum by HPLC analysis.
    International journal of clinical pharmacology and therapeutics, 2002, Volume: 40, Issue:12

    Topics: Antidepressive Agents, Second-Generation; Antipsychotic Agents; Chromatography, High Pressure Liquid; Citalopram; Clozapine; Fluoxetine; Humans; Maprotiline; Trazodone

2002