maprotiline has been researched along with desipramine in 81 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 35 (43.21) | 18.7374 |
| 1990's | 14 (17.28) | 18.2507 |
| 2000's | 15 (18.52) | 29.6817 |
| 2010's | 14 (17.28) | 24.3611 |
| 2020's | 3 (3.70) | 2.80 |
| Authors | Studies |
|---|---|
| Medina-Hernández, MJ; Quiñones-Torrelo, C; Sagrado, S; Villanueva-Camañas, RM | 1 |
| Topliss, JG; Yoshida, F | 1 |
| Adkison, KK; Humphreys, JE; Mahar Doan, KM; Polli, JW; Serabjit-Singh, CJ; Shampine, LJ; Webster, LO; Wring, SA | 1 |
| Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY | 1 |
| Bacsó, Z; Cianfriglia, M; Fenyvesi, F; Goda, K; Kappelmayer, J; Lustyik, G; Nagy, H; Szabó, G; Szilasi, M | 1 |
| Johans, C; Kinnunen, PK; Söderlund, T; Suomalainen, P | 1 |
| Ikeda, K; Kobayashi, T; Washiyama, K | 1 |
| Bleich, S; Gulbins, E; Kornhuber, J; Reichel, M; Terfloth, L; Tripal, P; Wiltfang, J | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Ahman, M; Holmén, AG; Wan, H | 1 |
| Alfinito, P; Bray, JA; Coghlan, RD; Cosmi, SA; Deecher, DC; Heffernan, GD; Huselton, C; Johnston, GH; Kenney, T; Koury, E; Li, Y; Mahaney, PE; Manas, ES; McDevitt, RE; Robichaud, AJ; Trybulski, EJ; Winneker, RC | 1 |
| Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM | 1 |
| García-Mera, X; González-Díaz, H; Prado-Prado, FJ | 1 |
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Glen, RC; Lowe, R; Mitchell, JB | 1 |
| Gozalbes, R; Pineda-Lucena, A | 1 |
| Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V | 1 |
| Fijorek, K; Glinka, A; Mendyk, A; Polak, S; Wiśniowska, B | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Bellman, K; Knegtel, RM; Settimo, L | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Jones, LH; Nadanaciva, S; Rana, P; Will, Y | 1 |
| Cardoso, FC; Duggan, PJ; Kuiper, MJ; Lewis, RJ; Schmit, M; Tuck, KL | 1 |
| Albert, W; Klicpera, C; Strian, F | 1 |
| Huey, LY; Janowsky, DS; Risch, SC | 1 |
| Frommer, R; Yehuda, S | 1 |
| Claeys, M; Maenhaut, W; Markey, SP | 1 |
| Biamino, G; Neye, G; Neye, J; Nöring, J | 1 |
| Erez, M; Manoach, M; Varon, D; Wozner, D | 1 |
| Engberg, G; Nissbrandt, H; Pileblad, E | 1 |
| Nakamura, S | 1 |
| Bönisch, H; Coppeneur, D; Lingen, B; Martiny-Baron, G; Paulus, G | 1 |
| Goromaru, T; Hashimoto, K | 1 |
| Carboni, E; Di Chiara, G; Frau, R; Tanda, GL | 1 |
| Campbell, IC; Ellison, DW | 1 |
| Nakanishi, T; Yoshida, M | 1 |
| Asakura, M; Imafuku, J; Kubota, H; Nakanishi, J; Nishizaki, J; Osada, K; Sato, A; Shibata, M; Shimbo, K; Tsukamoto, T | 1 |
| Eisen, JN; Irwin, J; Livnat, S; Quay, J | 1 |
| Craven, JL; Kennedy, SH; Rodin, GM; Roin, GM | 1 |
| Asakura, M; Hasegawa, K; Imafuku, J; Ino, M; Kubota, H; Nishizaki, J; Sato, A; Shinbo, K; Tsukamoto, T | 1 |
| Barbaccia, ML; Costa, E; Szekely, AM | 1 |
| Mogilnicka, E; Wedzony, K; Zazula, M | 1 |
| Nowak, G; Pawłowski, L | 1 |
| Barbaccia, ML; Costa, E; Ravizza, L | 1 |
| Archer, T; Danysz, W; Fowler, CJ | 1 |
| Abrahamsson, T; Carlsson, L | 1 |
| Baumann, P; Cuendet, C; Eap, CB | 1 |
| Marsden, CA; Routledge, C | 1 |
| Joffe, RT; Richter, MA | 1 |
| Arendt, J; Burton, S; Checkley, SA; Franey, C; Thompson, C | 1 |
| Clifford, DB; Hicks, FG; Rutherford, JL; Zorumski, CF | 1 |
| Kameyama, T; Nagasaka, M; Yamada, K | 1 |
| Cavero, I; Lefèvre-Borg, F; Roach, AG | 1 |
| Archer, T; Minor, BG; Ross, SB | 1 |
| Cavero, I; Gomeni, R; Lefèvre-Borg, F; Roach, AG | 1 |
| Gillespie, DD; Lovell, RA; Mishra, R; Robson, RD; Sulser, F | 1 |
| Bradford, D; Krijzer, F; Snelder, M | 1 |
| Itoh, M; Nakao, H; Notomi, A; Yufu, N | 1 |
| Feinberg, M; Genero, N; Greden, JF; Levine, S; Price, HL | 1 |
| Maj, J; Rogóz, Z; Skuza, G; Sowińska, H | 1 |
| Forette, F; Gomeni, R; Henry, JF; Hervy, MP; Hrdina, PD; Morselli, PL; Rovei, V | 1 |
| Hamilton, JD | 1 |
| Devoize, JL; Eschalier, A; Pechadre, JC; Rigal, F | 1 |
| Laakmann, G | 1 |
| Baker, GB; McManus, DJ; Todd, KG | 1 |
| Blier, P; De Montigny, C; Mongeau, R | 1 |
| Borsini, F; Ceci, A | 1 |
| Bourin, M; Redrobe, JP | 1 |
| Nakashita, M; Saito, N; Sakai, N; Sasaki, K | 1 |
| Blomgren, B; Dahlin, KL; Lâstbom, L; Ryrfeldt, A | 1 |
| Eiring, A; Sulser, F | 1 |
| Arai, S; Dohi, T; Kihira, K; Kitayama, S; Kumagai, K; Kumagai, M; Morita, K | 1 |
| Eckhardt, K; Feuerstein, TJ; Günter, T; Roth, P; Schmidt, S | 1 |
| Belzung, C; Surget, A; Yalcin, I | 1 |
| Coburn, KL; Doonan, SM; Lauterbach, EC; Mendez, MF; Shillcutt, SD; Victoroff, J | 1 |
| Asakura, M; Fujiwara, K; Kanai, S; Nakano, M; Osada, K; Sasuga, Y; Tanaka, D; Yanagida, T | 1 |
| Giles, R; Girard, MFC; Hopfgartner, G; Knight, P | 1 |
| Yamini, Y; Zamani, R | 1 |
3 review(s) available for maprotiline and desipramine
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Axonal sprouting of noradrenergic locus coeruleus neurons following repeated stress and antidepressant treatment.
Topics: Animals; Antidepressive Agents; Axons; Chronic Disease; Desipramine; Electroconvulsive Therapy; Electrophysiology; Female; Immersion; Locus Coeruleus; Maprotiline; Mianserin; Models, Neurological; Nerve Regeneration; Neuronal Plasticity; Oxidopamine; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Stimulation, Chemical; Stress, Physiological | 1991 |
Psychopharmacological neuroprotection in neurodegenerative disease: assessing the preclinical data.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Antioxidants; Antipsychotic Agents; Benzodiazepines; Benzothiazoles; Brain; Clonazepam; Desipramine; Dibenzothiazepines; Dopamine Agonists; Humans; Lithium Carbonate; Maprotiline; Melatonin; Neurodegenerative Diseases; Neuroprotective Agents; Olanzapine; Parkinson Disease; Pramipexole; Quetiapine Fumarate; Selective Serotonin Reuptake Inhibitors; Valproic Acid | 2010 |
2 trial(s) available for maprotiline and desipramine
| Article | Year |
|---|---|
Major depression in renal dialysis patients: an open trial of antidepressant therapy.
Topics: Aged; Antidepressive Agents; Clinical Trials as Topic; Depressive Disorder; Desipramine; Humans; Kidney Failure, Chronic; Male; Maprotiline; Mianserin; Placebos; Psychiatric Status Rating Scales; Renal Dialysis | 1989 |
Clinical studies of the effect of (+) and (-)-oxaprotiline upon noradrenaline uptake.
Topics: Anthracenes; Antidepressive Agents; Desipramine; Humans; Male; Maprotiline; Melatonin; Norepinephrine; Pupil; Stereoisomerism | 1985 |
76 other study(ies) available for maprotiline and desipramine
| Article | Year |
|---|---|
Development of predictive retention-activity relationship models of tricyclic antidepressants by micellar liquid chromatography.
Topics: Adenylyl Cyclase Inhibitors; Adrenergic alpha-Antagonists; Animals; Antidepressive Agents, Tricyclic; Chromatography, Liquid; Enzyme Inhibitors; Histamine H1 Antagonists; Micelles; Models, Biological; Norepinephrine; Rats; Receptors, Adrenergic, alpha-1; Selective Serotonin Reuptake Inhibitors; Serotonin; Structure-Activity Relationship | 1999 |
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Passive permeability and P-glycoprotein-mediated efflux differentiate central nervous system (CNS) and non-CNS marketed drugs.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blood-Brain Barrier; Cell Line; Cell Membrane Permeability; Central Nervous System Agents; Dogs; Drug Delivery Systems; Permeability; Pharmaceutical Preparations | 2002 |
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution | 2004 |
Distinct groups of multidrug resistance modulating agents are distinguished by competition of P-glycoprotein-specific antibodies.
Topics: Adenosine Triphosphatases; Animals; Anti-Bacterial Agents; Antibodies, Monoclonal; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Binding, Competitive; Calcium Channel Blockers; Cyclosporine; Detergents; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Flow Cytometry; Fluoresceins; Humans; Ivermectin; Mice; NIH 3T3 Cells; Substrate Specificity | 2004 |
Surface activity profiling of drugs applied to the prediction of blood-brain barrier permeability.
Topics: Blood-Brain Barrier; Lipid Bilayers; Micelles; Permeability; Pharmaceutical Preparations; Structure-Activity Relationship; Surface Properties | 2004 |
Inhibition of G protein-activated inwardly rectifying K+ channels by various antidepressant drugs.
Topics: Animals; Antidepressive Agents; Antidepressive Agents, Tricyclic; Electrophysiology; Female; G Protein-Coupled Inwardly-Rectifying Potassium Channels; GTP-Binding Proteins; Heart; Humans; Myocardium; Oocytes; Potassium Channel Blockers; Potassium Channels, Inwardly Rectifying; RNA, Messenger; Xenopus laevis | 2004 |
Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model.
Topics: Algorithms; Animals; Cell Line; Cell Line, Tumor; Chemical Phenomena; Chemistry, Physical; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Molecular Conformation; Quantitative Structure-Activity Relationship; Rats; Sphingomyelin Phosphodiesterase | 2008 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship | 2008 |
Relationship between brain tissue partitioning and microemulsion retention factors of CNS drugs.
Topics: Brain; Central Nervous System; Chromatography, Liquid; Emulsions; Mass Spectrometry | 2009 |
Dual acting norepinephrine reuptake inhibitors and 5-HT(2A) receptor antagonists: Identification, synthesis and activity of novel 4-aminoethyl-3-(phenylsulfonyl)-1H-indoles.
Topics: Biological Transport; Cell Line; Humans; Indoles; Neurotransmitter Uptake Inhibitors; Norepinephrine; Receptor, Serotonin, 5-HT2A; Serotonin 5-HT2 Receptor Antagonists; Serotonin Antagonists; Structure-Activity Relationship | 2009 |
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
Topics: | 2008 |
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
Predicting phospholipidosis using machine learning.
Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine | 2010 |
QSAR-based solubility model for drug-like compounds.
Topics: Databases, Factual; Models, Molecular; Pharmaceutical Preparations; Quantitative Structure-Activity Relationship; Solubility; Water | 2010 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
FDA-approved drug labeling for the study of drug-induced liver injury.
Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration | 2011 |
Predictive model for L-type channel inhibition: multichannel block in QT prolongation risk assessment.
Topics: Artificial Intelligence; Calcium Channel Blockers; Calcium Channels, L-Type; Cell Line; Computational Biology; Computer Simulation; Drugs, Investigational; Ether-A-Go-Go Potassium Channels; Expert Systems; Heart Rate; Humans; Models, Biological; Myocytes, Cardiac; NAV1.5 Voltage-Gated Sodium Channel; Potassium Channel Blockers; Quantitative Structure-Activity Relationship; Risk Assessment; Shaker Superfamily of Potassium Channels; Torsades de Pointes; Voltage-Gated Sodium Channel Blockers | 2012 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation | 2014 |
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships.
Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone | 2016 |
Inhibition of N-type calcium ion channels by tricyclic antidepressants - experimental and theoretical justification for their use for neuropathic pain.
Topics: | 2022 |
Effects of somatic treatments on mood in endogenous depression.
Topics: Adolescent; Adult; Aged; Amitriptyline; Antidepressive Agents; Clomipramine; Depression; Desipramine; Electroconvulsive Therapy; Emotions; Evaluation Studies as Topic; Female; Humans; Male; Maprotiline; Middle Aged; Psychological Tests; Time Factors | 1979 |
Plasma levels of tricyclic antidepressants and clinical efficacy: review of the literature -- part II.
Topics: Antidepressive Agents, Tricyclic; Biotransformation; Clomipramine; Depression; Desipramine; Dibenzocycloheptenes; Dose-Response Relationship, Drug; Doxepin; Drug Interactions; Humans; Imipramine; Maprotiline; Protriptyline | 1979 |
The thermal effects of interaction between d-amphetamine and antidepressants among rats kept at various ambient temperatures.
Topics: Animals; Antidepressive Agents; Body Temperature; Clomipramine; Desipramine; Dextroamphetamine; Dose-Response Relationship, Drug; Drug Interactions; Male; Maprotiline; Rats | 1977 |
Variance analysis of error in selected ion monitoring assays using various internal standards. A practical study case.
Topics: Analysis of Variance; Chromatography, Gas; Desipramine; Imipramine; Maprotiline; Mass Spectrometry; Methods; Promazine; Regression Analysis; Time Factors | 1977 |
[Proceedings: Effect of tricyclic antidepressive agents and of Nomifensin (Hoe984) on the contractile properties of the isolated papillary muscle and on the tonus of the smooth vascular muscles].
Topics: Acridines; Animals; Anthracenes; Antidepressive Agents, Tricyclic; Cats; Desipramine; Imipramine; Isoquinolines; Maprotiline; Muscle Contraction; Muscle, Smooth; Papillary Muscles; Rats | 1975 |
Ventricular defibrillating properties of catecholamine uptake inhibitors.
Topics: Amphetamine; Animals; Antidepressive Agents, Tricyclic; Cats; Cocaine; Desipramine; Electrocardiography; Female; Iprindole; Male; Maprotiline; Mianserin; Ventricular Fibrillation | 1992 |
The effects of GBR 12909, a dopamine re-uptake inhibitor, on monoaminergic neurotransmission in rat striatum, limbic forebrain, cortical hemispheres and substantia nigra.
Topics: 5-Hydroxytryptophan; alpha-Methyltyrosine; Animals; Cerebral Cortex; Corpus Striatum; Desipramine; Dihydroxyphenylalanine; Dopamine; Hydrazines; Limbic System; Locus Coeruleus; Male; Maprotiline; Methyltyrosines; Neurotransmitter Uptake Inhibitors; Norepinephrine; Normetanephrine; Oxidopamine; Pargyline; Piperazines; Prosencephalon; Rats; Rats, Inbred Strains; Serotonin; Substantia Nigra; Synaptic Transmission | 1991 |
Molecular aspects of the neuronal noradrenaline transporter.
Topics: Adrenal Medulla; Animals; Carrier Proteins; Cattle; Cell Membrane; Chromatography, Affinity; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Desipramine; Iprindole; Maprotiline; Norepinephrine; Norepinephrine Plasma Membrane Transport Proteins; Oocytes; PC12 Cells; Poly A; RNA; RNA, Messenger; Symporters; Xenopus laevis | 1991 |
High-affinity [3H]6-nitroquipazine binding to the 5-hydroxytryptamine transport system in rat lung.
Topics: Animals; Biological Transport; Desipramine; Imipramine; Kinetics; Lung; Male; Maprotiline; Membranes; Quipazine; Rats; Rats, Inbred Strains; Serotonin; Stereoisomerism; Temperature; Tritium; Zimeldine | 1991 |
Blockade of the noradrenaline carrier increases extracellular dopamine concentrations in the prefrontal cortex: evidence that dopamine is taken up in vivo by noradrenergic terminals.
Topics: Animals; Caudate Nucleus; Desipramine; Dopamine; Drug Synergism; Extracellular Space; Frontal Lobe; Haloperidol; Hydroxydopamines; Male; Maprotiline; Norepinephrine; Oxidopamine; Rats; Rats, Inbred Strains | 1990 |
Studies on the role of alpha 2-adrenoceptors in the control of synaptosomal [3H]5-hydroxytryptamine release: effects of antidepressant drugs.
Topics: Animals; Antidepressive Agents; Benzylamines; Cerebral Cortex; Citalopram; Clonidine; Clorgyline; Desipramine; Hydroxyindoleacetic Acid; Male; Maprotiline; Nomifensine; Potassium; Propylamines; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Serotonin; Synaptosomes; Yohimbine | 1986 |
[Inhibitory effects of L-threo-DOPS on electroshock seizure in mice].
Topics: Animals; Anticonvulsants; Desipramine; Droxidopa; Drug Therapy, Combination; Electroshock; Male; Maprotiline; Mice; Mice, Inbred Strains; Nialamide; Seizures; Serine | 1989 |
Involvement of protein kinase in the regulation of beta-adrenergic receptors by antidepressants.
Topics: 5-Hydroxytryptophan; 5,7-Dihydroxytryptamine; Animals; Antidepressive Agents; Bucladesine; Cerebral Cortex; Desipramine; Fluoxetine; Injections, Intraventricular; Male; Maprotiline; Mianserin; Protein Kinase Inhibitors; Protein Kinases; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Time Factors | 1989 |
The effect of antidepressants on immune function in mice.
Topics: Animals; Anthracenes; B-Lymphocytes; Cell Line; Cytotoxicity, Immunologic; Desipramine; Dose-Response Relationship, Drug; Hypersensitivity, Delayed; Immunocompetence; Killer Cells, Natural; Lymphocyte Activation; Male; Maprotiline; Mice; Mice, Inbred C3H; T-Lymphocytes; Tumor Cells, Cultured | 1989 |
Role of serotonin in the regulation of beta-adrenoceptors by antidepressants.
Topics: 5-Hydroxytryptophan; Animals; Antidepressive Agents; Cerebral Cortex; Desipramine; Fenclonine; Fluoxetine; In Vitro Techniques; Male; Maprotiline; Membranes; Mianserin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Serotonin | 1987 |
Effect of a protracted antidepressant treatment on signal transduction and [3H](-)-baclofen binding at GABAB receptors.
Topics: Adenylyl Cyclases; Animals; Anthracenes; Baclofen; Cerebral Cortex; Colforsin; Desipramine; Drug Administration Schedule; Imipramine; Injections, Intraperitoneal; Kinetics; Male; Maprotiline; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1987 |
Functional supersensitivity to the alpha 1-adrenoceptor agonist after repeated treatment with antidepressant drugs is not conditioned by beta-down-regulation.
Topics: Adrenergic alpha-Agonists; Animals; Antidepressive Agents; Brain Chemistry; Desipramine; Dihydroalprenolol; Male; Maprotiline; Motor Activity; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta | 1987 |
Biochemical and pharmacological tests for the prediction of ability of monoamine uptake blockers to inhibit the uptake of noradrenaline in-vivo: the effects of desipramine, maprotiline, femoxetine and citalopram.
Topics: Animals; Apomorphine; Body Temperature; Brain; Citalopram; Desipramine; Male; Maprotiline; Mice; Monoamine Oxidase Inhibitors; Norepinephrine; Piperidines; Propylamines; Reserpine; Serotonin Antagonists; Thyrotropin-Releasing Hormone; Tyramine | 1987 |
Maprotiline: an antidepressant with an unusual pharmacological profile.
Topics: Animals; Anthracenes; Brain; Carbolines; Desipramine; Flunitrazepam; In Vitro Techniques; Male; Maprotiline; Norepinephrine; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Receptors, GABA-A; Receptors, Serotonin; Tritium | 1986 |
Noradrenaline-stimulated inositol phospholipid breakdown as a measure of alpha 1-adrenoceptor function in rat hippocampal miniprisms after repeated antidepressant treatment.
Topics: Animals; Antidepressive Agents; Desipramine; Hippocampus; Male; Maprotiline; Mianserin; Norepinephrine; Phosphatidylinositols; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Zimeldine | 1986 |
Characterization of the inhibitory effect of some antidepressant drugs on the outward transport of norepinephrine in the ischemic myocardium.
Topics: Animals; Antidepressive Agents; Biological Transport, Active; Chromatography, High Pressure Liquid; Clonidine; Coronary Disease; Desipramine; Fluoxetine; Heart; Isomerism; Lidocaine; Male; Maprotiline; Myocardium; Norepinephrine; Rats; Rats, Inbred Strains | 1988 |
Selectivity in the binding of psychotropic drugs to the variants of alpha-1 acid glycoprotein.
Topics: Amitriptyline; Clomipramine; Desipramine; Hydrogen-Ion Concentration; Imipramine; Maprotiline; Methadone; Orosomucoid; Psychotropic Drugs; Thioridazine; Trimipramine | 1988 |
Lack of selectivity between the uptake of [3H]adrenaline and [3H]noradrenaline into rat hypothalamic slices.
Topics: Animals; Benztropine; Desipramine; Epinephrine; Fluoxetine; Hypothalamus; Male; Maprotiline; Norepinephrine; Rats; Rats, Inbred Strains; Tissue Distribution | 1987 |
Use of tricyclic antidepressants in a patient with malignant hyperthermia.
Topics: Adult; Antidepressive Agents, Tricyclic; Depressive Disorder; Desipramine; Female; Humans; Malignant Hyperthermia; Maprotiline; Trimipramine | 1987 |
Acute effects of antidepressants on hippocampal seizures.
Topics: Amitriptyline; Animals; Anticonvulsants; Antidepressive Agents; Bupropion; Desipramine; Epilepsy; Hippocampus; Imipramine; Maprotiline; Propiophenones; Rats; Trazodone | 1985 |
Effects of antidepressant drugs on a quickly-learned conditioned-suppression response in mice.
Topics: Acridines; Amitriptyline; Animals; Antidepressive Agents; Depressive Disorder; Desipramine; Diphenhydramine; Disease Models, Animal; Electroshock; Ethanol; Humans; Imipramine; Male; Maprotiline; Mianserin; Mice; Motor Activity; Nialamide; Pargyline; Tranylcypromine | 1985 |
Effects of mianserin, desipramine and maprotiline on blood pressure responses evoked by acetylcholine, histamine and 5-hydroxytryptamine in rats.
Topics: Acetylcholine; Animals; Antidepressive Agents, Tricyclic; Blood Pressure; Desipramine; Drug Interactions; Histamine; Male; Maprotiline; Mianserin; Rats; Rats, Inbred Strains; Reserpine; Serotonin | 1981 |
Attenuation of the post-decapitation convulsions after repeated treatment of rats with desipramine, imipramine and maprotiline.
Topics: Alanine; Animals; Anticonvulsants; Antidepressive Agents; Desipramine; Imipramine; Male; Maprotiline; Rats; Rats, Inbred Strains; Time Factors; Zimeldine | 1984 |
Comparison of mianserin with desipramine, maprotiline and phentolamine on cardiac presynaptic and vascular postsynaptic alpha-adrenoceptors and noradrenaline reuptake in pithed normotensive rats.
Topics: Animals; Anthracenes; Blood Vessels; Cardiovascular System; Clonidine; Desipramine; Dibenzazepines; Drug Interactions; Heart; Male; Maprotiline; Mianserin; Norepinephrine; Phentolamine; Rats; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Spinal Cord | 1980 |
Oxaprotiline: induction of central noradrenergic subsensitivity of its (+)-enantiomer.
Topics: Animals; Anthracenes; Cerebral Cortex; Cyclic AMP; Desipramine; Dihydroalprenolol; In Vitro Techniques; Male; Maprotiline; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Receptors, Adrenergic, beta; Stereoisomerism; Synaptosomes; Time Factors | 1982 |
Comparison of the (pro)convulsive properties of fluvoxamine and clovoxamine with eight other antidepressants in an animal model.
Topics: Amitriptyline; Animals; Antidepressive Agents; Desipramine; Disease Models, Animal; Dose-Response Relationship, Drug; Electroencephalography; Epilepsy; Fluvoxamine; Imipramine; Male; Maprotiline; Mianserin; Oximes; Rats; Rats, Inbred Strains; Seizures; Viloxazine | 1984 |
Simultaneous measurement of various antidepressants in the plasma of depressed patients by high performance liquid chromatography.
Topics: Adult; Amitriptyline; Amoxapine; Antidepressive Agents; Chromatography, High Pressure Liquid; Clomipramine; Depressive Disorder; Desipramine; Dose-Response Relationship, Drug; Female; Humans; Imipramine; Male; Maprotiline; Middle Aged; Nortriptyline | 1984 |
Facial EMG activity levels predict treatment outcome in depression.
Topics: Amitriptyline; Antidepressive Agents; Bipolar Disorder; Depressive Disorder; Desipramine; Electromyography; Facial Expression; Facial Muscles; Female; Humans; Imipramine; Maprotiline; Middle Aged; Muscle Contraction; Prognosis; Psychiatric Status Rating Scales | 1984 |
The effect of selective inhibitors of noradrenaline and serotonin uptake on reserpine- and apomorphine induced hypothermia in mice.
Topics: Animals; Apomorphine; Body Temperature; Citalopram; Desipramine; Fluoxetine; Male; Maprotiline; Mice; Norepinephrine; Propylamines; Reserpine; Serotonin Antagonists | 1983 |
Comparison of single-dose pharmacokinetics of imipramine and maprotiline in the elderly.
Topics: Aged; Anthracenes; Biological Availability; Desipramine; Female; Half-Life; Hemodynamics; Humans; Imipramine; Kinetics; Maprotiline | 1980 |
Cross-reaction to maprotiline.
Topics: Adult; Anthracenes; Cross Reactions; Desipramine; Drug Hypersensitivity; Female; Humans; Maprotiline | 1983 |
Activities of five antidepressants in a behavioral pain test in rats.
Topics: Analgesia; Animals; Antidepressive Agents; Clomipramine; Desipramine; Electroshock; Male; Maprotiline; Nociceptors; Nomifensine; Rats; Rats, Inbred Strains; Viloxazine | 1983 |
[Effect of antidepressants on the secretion of pituitary hormones in healthy subjects, neurotic depressive patients and endogenous depressive patients (author's transl)].
Topics: Adult; Anthracenes; Clomipramine; Depressive Disorder; Desipramine; Female; Growth Hormone; Humans; Isoquinolines; Luteinizing Hormone; Male; Maprotiline; Middle Aged; Nomifensine; Pituitary Hormones, Anterior; Prolactin; Thyrotropin | 1980 |
Chronic administration of the antidepressants phenelzine, desipramine, clomipramine, or maprotiline decreases binding to 5-hydroxytryptamine2A receptors without affecting benzodiazepine binding sites in rat brain.
Topics: Animals; Anti-Anxiety Agents; Antidepressive Agents; Brain; Clomipramine; Desipramine; Flunitrazepam; Fluoxetine; Ketanserin; Male; Maprotiline; Phenelzine; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2A; Receptors, GABA-A; Receptors, Serotonin; Serotonin Antagonists | 1995 |
Effect of long-term administration of antidepressant drugs on the 5-HT3 receptors that enhance the electrically evoked release of [3H]noradrenaline in the rat hippocampus.
Topics: Animals; Antidepressive Agents; Benzamides; Desipramine; Electric Stimulation; Fluoxetine; Hippocampus; In Vitro Techniques; Male; Maprotiline; Moclobemide; Norepinephrine; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Serotonin; Trimipramine | 1994 |
Effects of desipramine and maprotiline on the coeruleus-cortical noradrenergic system in anaesthetized rats.
Topics: Animals; Desipramine; Locus Coeruleus; Male; Maprotiline; Neurons; Norepinephrine; Oxidopamine; Rats; Rats, Sprague-Dawley | 1996 |
Partial role of 5-HT2 and 5-HT3 receptors in the activity of antidepressants in the mouse forced swimming test.
Topics: Amphetamines; Animals; Antidepressive Agents; Behavior, Animal; Citalopram; Desipramine; Drug Interactions; Fluoxetine; Fluvoxamine; Imipramine; Ketanserin; Male; Maprotiline; Mice; Ondansetron; Receptors, Serotonin; Receptors, Serotonin, 5-HT3; Ritanserin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Swimming | 1997 |
Effects of tricyclic and tetracyclic antidepressants on the three subtypes of GABA transporter.
Topics: Amitriptyline; Animals; Antidepressive Agents; Antidepressive Agents, Tricyclic; Biological Transport; Carrier Proteins; Desipramine; Dose-Response Relationship, Drug; GABA Plasma Membrane Transport Proteins; Maprotiline; Membrane Proteins; Membrane Transport Proteins; Organic Anion Transporters | 1997 |
Acute lung failure induced by tricyclic antidepressants.
Topics: Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Desipramine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Overdose; Imipramine; Lung; Maprotiline; Mianserin; Microscopy, Electron; Nortriptyline; Organ Size; Perfusion; Pulmonary Edema; Pulmonary Ventilation; Rats; Rats, Sprague-Dawley | 1997 |
Increased synaptic availability of norepinephrine following desipramine is not essential for increases in GR mRNA. Short communication.
Topics: Adrenergic Uptake Inhibitors; Animals; Antidepressive Agents; Desipramine; Male; Maprotiline; Norepinephrine; Rats; Rats, Sprague-Dawley; Receptors, Glucocorticoid; RNA, Messenger; Synapses | 1997 |
Chronic inhibition of the norepinephrine transporter in the brain participates in seizure sensitization to cocaine and local anesthetics.
Topics: Adrenergic Uptake Inhibitors; Anesthetics, Local; Animals; Brain; Brain Chemistry; Citalopram; Cocaine; Desipramine; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Lidocaine; Male; Maprotiline; Mice; Mice, Inbred ICR; Norepinephrine Plasma Membrane Transport Proteins; Piperazines; Seizures; Selective Serotonin Reuptake Inhibitors; Symporters; Time Factors | 2003 |
Differential effects of K(ATP) channel blockers on [(3)H]-noradrenaline overflow after short- and long-term exposure to (+)-oxaprotiline or desipramine.
Topics: Adenosine Triphosphate; Adrenergic alpha-Agonists; Animals; Antidepressive Agents; Autoreceptors; Clonidine; Desipramine; Drug Interactions; Glyburide; In Vitro Techniques; Male; Maprotiline; Neocortex; Norepinephrine; Potassium Channel Blockers; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-2; Time Factors | 2003 |
Mouse strain differences in the unpredictable chronic mild stress: a four-antidepressant survey.
Topics: Animals; Animals, Outbred Strains; Antidepressive Agents; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Anxiety; Behavior, Animal; Chronic Disease; Depression; Desipramine; Fluoxetine; Grooming; Imipramine; Injections, Intraperitoneal; Male; Maprotiline; Mice; Mice, Inbred BALB C; Mice, Inbred DBA; Selective Serotonin Reuptake Inhibitors; Species Specificity; Stress, Psychological; Time Factors | 2008 |
[The delayed sensitization of CRH response developed after chronic variable stress on the acoustic startle reflex].
Topics: Animals; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Corticotropin-Releasing Hormone; Desipramine; Male; Maprotiline; Norepinephrine; Paroxetine; Rats; Rats, Wistar; Receptors, Corticotropin; Reflex, Acoustic; Reflex, Startle; Stress, Psychological; Time Factors | 2011 |
Effects of the LC mobile phase in vacuum differential mobility spectrometry-mass spectrometry for the selective analysis of antidepressant drugs in human plasma.
Topics: Acetonitriles; Amitriptyline; Antidepressive Agents; Desipramine; Humans; Imipramine; Maprotiline; Mass Spectrometry; Methanol; Nortriptyline; Reproducibility of Results; Spectrum Analysis; Vacuum; Venlafaxine Hydrochloride | 2022 |
On-Chip Electromembrane Surrounded Solid Phase Microextraction for Determination of Tricyclic Antidepressants from Biological Fluids Using Poly(3,4-ethylenedioxythiophene)-Graphene Oxide Nanocomposite as a Fiber Coating.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Desipramine; Humans; Imipramine; Limit of Detection; Maprotiline; Nanocomposites; Nortriptyline; Reproducibility of Results; Sertraline; Solid Phase Microextraction | 2023 |