mannose has been researched along with lysine in 44 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 25 (56.82) | 18.7374 |
| 1990's | 8 (18.18) | 18.2507 |
| 2000's | 7 (15.91) | 29.6817 |
| 2010's | 1 (2.27) | 24.3611 |
| 2020's | 3 (6.82) | 2.80 |
| Authors | Studies |
|---|---|
| Eipper, BA; Guenzi, D; Mains, RE | 1 |
| Gromska, W; Mayer, H | 1 |
| Shiomi, T; Watanabe, T | 1 |
| Chauvenet, AR; Scott, DW | 1 |
| Avi-Dor, Y; David, M | 1 |
| Gabius, HJ; Zeng, FY | 1 |
| McIntosh, DB; Ross, DC | 1 |
| Gorden, P; Rouiller, DG | 1 |
| Beisswenger, PJ | 1 |
| Butler, WT; Niedermeier, W; Stroud, RM; Yonemasu, K | 1 |
| Bartz, QR; Dion, HW; French, JC | 1 |
| Abramson, C; Rautela, GS | 1 |
| Goldstone, A; Koenig, H | 1 |
| Bezkorovainy, A; Denduchis, B; Kefalides, NA | 1 |
| Kress, LF; Laskowski, M; Martin, SR | 1 |
| Bourrillon, R; Jouanneau, J; Razafimahaleo, E | 1 |
| Derouette, S; Moczar, E; Robert, L | 1 |
| Goodman, HM | 1 |
| Terao, T; Tsuruo, T; Ukita, T; Yamashita, S | 1 |
| Moczar, E; Moczar, M | 1 |
| Cummins, CS | 1 |
| Fukushi, S; Spiro, RG | 1 |
| Bleiweis, AS; Coleman, SE | 1 |
| Kathan, RH; Reichert, LE; Ryan, RJ | 1 |
| Bernard, N; Cahour, A; Jouvin, MH; Kazatchkine, MD | 1 |
| Riezman, H; Schimmöller, F; Schröder, S; Singer-Krüger, B | 1 |
| Cuozzo, JW; Sahagian, GG; Tao, K; Wu, QL; Young, W | 1 |
| Cuozzo, JW; Sahagian, GG | 1 |
| Beck, PJ; Kogan, TP; Revelle, BM; Scott, D; Zheng, J | 1 |
| Albrecht, C; Meijer, DK; Reichen, J; Thormann, W; Visser, J | 1 |
| Cuozzo, JW; Cygler, M; Mort, JS; Sahagian, GG; Tao, K | 1 |
| Frenz, J; Gregory, W; Kornfeld, S; Nanda, A; Nishikawa, A | 1 |
| Aron, Y; Briand, P; Fajac, I; Grosse, S; Tremeau-Bravard, A | 1 |
| Bousser, MT; Drickamer, K; Frison, N; Mayer, R; Monsigny, M; Roche, AC; Soilleux, E; Taylor, ME | 1 |
| SLADE, HD; SLAMP, WC | 1 |
| Lederer, MO; Reihl, O; Rothenbacher, TM; Schwack, W | 1 |
| Chung, JK; Hong, MK; Jeong, JM; Kang, JH; Kim, YJ; Lee, DS; Lee, J; Lee, MC | 1 |
| Kornfeld, S; Lee, WS; Steet, R | 1 |
| Asan, H; Noguchi, A | 1 |
| Ganesh, S; Gour, N; Puri, R; Purohit, CS; Verma, S | 1 |
| Hirata, T; Ikeda, T; Kanagawa, A; Moroishi, N; Nagai, M; Nagai, R; Nakajima, A; Ohno, R; Shirakawa, J; Sugawa, H | 1 |
| Bruijns, SCM; Codée, JDC; Filippov, DV; Hogervorst, TP; Li, RJE; Marino, L; Meeuwenoord, NJ; Overkleeft, HS; van der Marel, GA; van Kooyk, Y; van Vliet, SJ | 1 |
| Bararpour, N; Darrous, L; Froguel, P; Gasser, M; Gilardi, F; Kutalik, Z; Marques-Vidal, P; Porcu, E; Thomas, A; Waeber, G; Yengo, L | 1 |
| Bolea Bailo, RM; Gu, Z; He, Y; Jiang, Y; Kong, D; López Lasaosa, F; Mao, H; Wei, J; Xu, S; Zhao, W | 1 |
44 other study(ies) available for mannose and lysine
| Article | Year |
|---|---|
High molecular weight forms of adrenocorticotropic hormone are glycoproteins.
Topics: Adrenocorticotropic Hormone; Cell Line; Glucosamine; Glycoproteins; Lysine; Mannose; Molecular Weight; Pituitary Neoplasms | 1976 |
The linkage of lysine in the O-specific chains of Proteus mirabilis 1959.
Topics: ABO Blood-Group System; Animals; Antigens, Bacterial; Binding Sites; Complement Fixation Tests; Glucose; Hexosamines; Hydrazines; Immunoelectrophoresis; Lysine; Mannose; Oligosaccharides; Polysaccharides, Bacterial; Proteus mirabilis; Rabbits; Uronic Acids | 1976 |
Inhibiting materials for gamma phage adsorption to the cell wall of Bacillus anthracis, strain Pasteur No. 2-H.
Topics: Acetone; Adsorption; Alanine; Bacillus anthracis; Bacteriophages; Cell Fractionation; Cell Wall; Diaminopimelic Acid; Ethers; Galactosamine; Glucosamine; Glutamates; Hot Temperature; Lysine; Mannose | 1975 |
A lectin model for unresponsiveness. I. Reversible effects of high doses of concanavalin A on spontaneous and induced DNA synthesis.
Topics: Animals; Cell Survival; Cells, Cultured; Chromium Radioisotopes; Concanavalin A; DNA; Dose-Response Relationship, Drug; Immunosuppression Therapy; Iodine Radioisotopes; Lectins; Lymphocyte Activation; Lymphocytes; Lysine; Male; Mannose; Rats; Rats, Inbred Lew; Thymus Gland | 1975 |
Stimulation of protein synthesis in cultured heart muscle cells by glucose.
Topics: Adenosine Triphosphate; Aminoisobutyric Acids; Animals; Biological Transport; Cells, Cultured; Cycloheximide; Dactinomycin; Glucose; Heart; Iodoacetates; Lactates; Leucine; Lysine; Mannose; Myocardium; Phenylalanine; Protein Biosynthesis; Proteins; Pyruvates; Rats; Stimulation, Chemical | 1975 |
Carbohydrate-binding specificity of calcyclin and its expression in human tissues and leukemic cells.
Topics: Acetylglucosamine; alpha-Fetoproteins; Animals; Arginine; Biotin; Calcium; Calcium-Binding Proteins; Carbohydrate Metabolism; Carbohydrates; Cattle; Cell Cycle Proteins; Cell Nucleus; Cytoplasm; G(M1) Ganglioside; Glycoproteins; Humans; Lactose; Leukemia; Lysine; Mannose; Mucins; Myocardium; S100 Calcium Binding Protein A6; S100 Proteins; Submandibular Gland; Tumor Cells, Cultured | 1991 |
Intramolecular cross-linking of domains at the active site links A1 and B subfragments of the Ca2+-ATPase of sarcoplasmic reticulum.
Topics: Adenosine Triphosphate; Animals; Binding Sites; Calcium-Transporting ATPases; Electrophoresis, Polyacrylamide Gel; Fluorescein-5-isothiocyanate; Fluoresceins; Glutaral; Lysine; Macromolecular Substances; Mannose; Molecular Weight; Nitrophenols; Organophosphorus Compounds; Peptide Fragments; Phosphorylation; Rabbits; Sarcoplasmic Reticulum; Thiocyanates; Trypsin; Vanadates; Vanadium | 1987 |
Homologous down-regulation of the insulin receptor is associated with increased receptor biosynthesis in cultured human lymphocytes (IM-9 line).
Topics: Cell Line; Humans; Insulin; Kinetics; Lymphocytes; Lysine; Mannose; Receptor, Insulin | 1987 |
Specificity of the chemical alteration in the diabetic glomerular basement membrane.
Topics: Acetylation; Adult; Aged; Amino Acids; Antigen-Antibody Complex; Autoanalysis; Basement Membrane; Cystine; Diabetes Mellitus; Fluorescent Antibody Technique; Galactose; Glucose; Humans; Hydrolysis; Hydroxylysine; Immunoglobulin G; Kidney Diseases; Kidney Glomerulus; Lupus Erythematosus, Systemic; Lysine; Mannose; Middle Aged; Proteinuria; Staining and Labeling | 1973 |
Chemical studies of Clq; a modulator of immunoglobulin biology.
Topics: Amino Acids; Animals; Antigens; Blood Proteins; Buffers; Carbohydrates; Chemical Precipitation; Collagen; Electrophoresis; Electrophoresis, Disc; Fucose; Galactose; Glucosamine; Glucose; Glycine; Glycoproteins; Hexosamines; Humans; Hydroxyproline; Immune Sera; Immunodiffusion; Immunoelectrophoresis; Immunoglobulin A; Immunoglobulin G; Immunoglobulin M; Lysine; Mannose; Neuraminic Acids; Osmolar Concentration; Oxidation-Reduction; Periodic Acid; Phenylalanine; Rats; Skin | 1971 |
Myomycin, a new antibiotic.
Topics: Aminoglycosides; Anti-Bacterial Agents; Bacteria; Chemical Phenomena; Chemistry; Fermentation; Hydrolysis; Inositol; Lysine; Mannose; Oxidation-Reduction; Periodic Acid | 1973 |
Crystallization and partial characterization of Staphylococcus aureus hyaluronate lyase.
Topics: Amino Acids; Chromatography, Gel; Chromatography, Ion Exchange; Crystallization; Electrophoresis, Disc; Galactosamine; Galactose; Glucosamine; Glucose; Histidine; Hyaluronoglucosaminidase; Kinetics; Lysine; Mannose; Molecular Weight; Spectrophotometry, Ultraviolet; Staphylococcus | 1973 |
Synthesis and turnover of lysosomal glycoproteins. Relation to the molecular heterogeneity of the lysosomal enzymes.
Topics: Acid Phosphatase; Animals; Carbon Radioisotopes; Glucosidases; Glucuronidase; Glycoproteins; Half-Life; Hexosamines; Hexosaminidases; Hydrogen-Ion Concentration; Isoelectric Focusing; Isotope Labeling; Kidney; Lysine; Lysosomes; Mannose; Microscopy, Electron; Neuraminic Acids; Rats; Sulfatases; Time Factors; Tritium | 1974 |
The chemistry of sheep anterior lens capsule.
Topics: Amino Acids; Animals; Carbohydrates; Chromatography, Paper; Collagen; Fucose; Galactose; Glucose; Glycine; Glycoproteins; Hexosamines; Hydroxyproline; Lens, Crystalline; Lysine; Mannose; Molecular Weight; Neuraminic Acids; Pepsin A; Peptide Hydrolases; Sheep; Viscosity | 1970 |
Isolation of isoinhibitors of trypsin from porcine colostrum.
Topics: Amino Acids; Animals; Binding Sites; Carboxypeptidases; Cattle; Chromatography, Ion Exchange; Chymotrypsin; Colostrum; Electrophoresis, Disc; Female; Fucose; Galactose; Glucosamine; Glucose; Hexosamines; Hydrogen-Ion Concentration; Lysine; Mannose; Methods; Neuraminic Acids; Pepsin A; Pregnancy; Sulfhydryl Compounds; Swine; Trypsin Inhibitors | 1971 |
[Glycopeptides of immunoglobulins, Microheterogeneity of the oligosaccharide chains of an immunoglobulin M from Waldenstrom's disease].
Topics: Amino Acid Sequence; Aspartic Acid; Autoanalysis; Chromatography, Gel; Chromatography, Ion Exchange; Electrophoresis; Fucose; Galactose; Glucosamine; Glutamates; Histidine; Humans; Immunoglobulin M; Immunoglobulins; Lysine; Mannose; Neuraminic Acids; Oligosaccharides; Papain; Peptides; Proline; Serine; Threonine; Tyrosine; Valine; Waldenstrom Macroglobulinemia | 1970 |
Biochemical studies on the aging of rat tail tendon.
Topics: Aging; Animals; Arginine; Calcium Chloride; Collagen; Fucose; Galactose; Glucose; Glycoproteins; Glycosides; Hexosamines; Hexoses; Hydroxyproline; Lysine; Mannose; Proteins; Rats; Tail; Tendons; Time Factors; Xylose | 1971 |
Growth hormone and the metabolism of carbohydrate and lipid in adipose tissue.
Topics: Adipose Tissue; Animals; Carbohydrate Metabolism; Carbon Isotopes; Cell Membrane Permeability; Cycloheximide; Dactinomycin; Depression, Chemical; Fatty Acids; Fructose; Galactose; Glucose; Growth Hormone; Insulin; Lipid Metabolism; Lysine; Mannose; Protein Biosynthesis; Puromycin; Pyruvates; Rats | 1968 |
Research on the carbohydrate-peptide linkage of porcine pancreatic ribonuclease.
Topics: Alkylation; Amino Acids; Amino Sugars; Animals; Carbohydrates; Chemical Phenomena; Chemistry; Chromatography, Gel; Chromatography, Ion Exchange; Chromatography, Paper; Chromatography, Thin Layer; Electrophoresis; Fucose; Galactose; Glucosamine; Glycoproteins; Lysine; Mannose; Models, Structural; Molecular Weight; Pancreas; Peptide Hydrolases; Peptides; Ribonucleases; Serine; Swine; Trypsin | 1970 |
The glycopeptide pattern of the porcine (Sus domesticus) and rabbit (Oryctolagus caniculus domesticus) corneal stroma.
Topics: Amino Acids; Animals; Carbohydrates; Chemical Phenomena; Chemistry; Chromatography, Gel; Chromatography, Thin Layer; Cornea; Densitometry; Electrophoresis; Endopeptidases; Galactose; Glycoproteins; Lysine; Mannose; Peptides; Polysaccharides; Rabbits; Species Specificity; Swine | 1970 |
Cell wall composition in Corynebacterium bovis and some other corynebacteria.
Topics: Amino Acids; Arabinose; Cell Wall; Chromatography, Paper; Corynebacterium; Galactose; Glucose; Lysine; Mannose; Monosaccharides; Pimelic Acids; Rhamnose; Species Specificity | 1971 |
The lens capsule. Sugar and amino acid composition.
Topics: Aging; Amino Acids; Animals; Carbohydrates; Cattle; Collagen; Fucose; Galactose; Glucosamine; Glucose; Glycine; Hexosamines; Hydrogen-Ion Concentration; Hydroxyproline; Kidney Glomerulus; Lens, Crystalline; Lysine; Mannose; Membranes; Neuraminic Acids; Peptides; Proline; Solubility; Uronic Acids; Vibration | 1969 |
Improved separation of components of streptococcal cell walls by thin-layer chromatography.
Topics: Alanine; Cell Wall; Chromatography, Thin Layer; Galactose; Glucosamine; Glucose; Glutamates; Glycerol; Lysine; Mannose; Methods; Rhamnose; Streptococcus | 1969 |
Comparison of the carbohydrate and amino acid composition of bovine, ovine and human luteinizing hormone.
Topics: Alanine; Amino Acids; Animals; Aspartic Acid; Cattle; Galactose; Glucosamine; Glutamates; Hexosamines; Hexoses; Humans; In Vitro Techniques; Luteinizing Hormone; Lysine; Mannose; Neuraminic Acids; Proline; Serine; Sheep; Threonine; Valine | 1967 |
Lysine residues, but not carbohydrates, are required for the regulatory function of H on the amplification C3 convertase of complement.
Topics: Acetylglucosamine; Carbohydrate Metabolism; Complement Activating Enzymes; Complement C3-C5 Convertases; Complement C3b; Complement C3b Inactivator Proteins; Complement Factor H; Galactose; Humans; Lysine; Mannose; Methylurea Compounds; N-Acetylneuraminic Acid; Neuraminidase; Protein Binding; Sialic Acids | 1984 |
The Golgi-localization of yeast Emp47p depends on its di-lysine motif but is not affected by the ret1-1 mutation in alpha-COP.
Topics: Amino Acid Sequence; Base Sequence; Coatomer Protein; Endoplasmic Reticulum; Fungal Proteins; Golgi Apparatus; Lectins; Lysine; Mannose; Mannose-Binding Lectins; Mannosyltransferases; Membrane Proteins; Molecular Sequence Data; Mutation; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Sequence Homology, Amino Acid; Subcellular Fractions; Vesicular Transport Proteins | 1995 |
Lysine-based structure in the proregion of procathepsin L is the recognition site for mannose phosphorylation.
Topics: 3T3 Cells; Animals; Cathepsin D; Cathepsin L; Cathepsins; Enzyme Precursors; Hydrogen-Ion Concentration; Lysine; Mannose; Mice; Mutation; Phosphorylation | 1995 |
Lysine is a common determinant for mannose phosphorylation of lysosomal proteins.
Topics: Animals; Cathepsin L; Cathepsins; Cell Line; Cysteine Endopeptidases; Electrophoresis, Polyacrylamide Gel; Endopeptidases; Enzyme Precursors; Glycoproteins; Kinetics; Lysine; Lysosomes; Mannose; Mice; Mice, Inbred Strains; N-Acetylglucosaminyltransferases; Phosphorylation; Protein Processing, Post-Translational | 1994 |
Structure-function analysis of P-selectin-sialyl LewisX binding interactions. Mutagenic alteration of ligand binding specificity.
Topics: Alanine; Amino Acid Sequence; Base Sequence; beta-Fructofuranosidase; Binding Sites; Conserved Sequence; DNA Primers; Galactose; Glycoside Hydrolases; HL-60 Cells; Humans; Kinetics; Lewis Blood Group Antigens; Lysine; Mannose; Molecular Sequence Data; Mutagenesis, Site-Directed; Oligosaccharides; P-Selectin; Polymerase Chain Reaction; Protein Binding; Recombinant Proteins; Sequence Homology, Amino Acid; Sialyl Lewis X Antigen; Structure-Activity Relationship; Substrate Specificity; Transfection | 1996 |
Differentiation between naproxen, naproxen-protein conjugates, and naproxen-lysine in plasma via micellar electrokinetic capillary chromatography--a new approach in the bioanalysis of drug targeting preparations.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Chromatography, High Pressure Liquid; Drug Carriers; Electrophoresis, Capillary; Humans; Lasers; Lysine; Male; Mannose; Naproxen; Protein Binding; Rats; Rats, Wistar; Serum Albumin; Spectrometry, Fluorescence | 1997 |
Lysine-based structure responsible for selective mannose phosphorylation of cathepsin D and cathepsin L defines a common structural motif for lysosomal enzyme targeting.
Topics: Animals; Base Sequence; Cathepsin D; Cathepsin L; Cathepsins; COS Cells; Cysteine Endopeptidases; DNA, Complementary; Endopeptidases; Humans; Lysine; Lysosomes; Mannose; Models, Molecular; Mutagenesis, Site-Directed; Phosphorylation; Protein Conformation | 1998 |
Identification of amino acids that modulate mannose phosphorylation of mouse DNase I, a secretory glycoprotein.
Topics: Amino Acid Sequence; Amino Acids; Animals; Cattle; COS Cells; Deoxyribonuclease I; Lysine; Mannose; Mice; Models, Molecular; Molecular Sequence Data; Phosphorylation; Point Mutation; Recombinant Fusion Proteins; Sequence Alignment; Serine; Tyrosine | 1999 |
Intracellular rate-limiting steps of gene transfer using glycosylated polylysines in cystic fibrosis airway epithelial cells.
Topics: Cystic Fibrosis; Epithelial Cells; Gene Expression; Genetic Therapy; Genetic Vectors; Humans; Lactose; Luciferases; Lysine; Mannose; Plasmids; Respiratory Mucosa; Second Messenger Systems; Transcription, Genetic; Tumor Cells, Cultured | 2002 |
Oligolysine-based oligosaccharide clusters: selective recognition and endocytosis by the mannose receptor and dendritic cell-specific intercellular adhesion molecule 3 (ICAM-3)-grabbing nonintegrin.
Topics: Adoptive Transfer; Cell Adhesion Molecules; Dendritic Cells; Endocytosis; Flow Cytometry; Fucose; Humans; Lectins; Lectins, C-Type; Ligands; Lysine; Mannose; Mannose Receptor; Mannose-Binding Lectins; Oligosaccharides; Receptors, Cell Surface; Surface Plasmon Resonance | 2003 |
Cell-wall composition and the grouping antigens of Streptococci.
Topics: Alanine; Antigens; Carbohydrate Metabolism; Carbohydrates; Cell Wall; Galactosamine; Galactose; Glucosamine; Glucose; Hexoses; Lysine; Mannose; Rhamnose; Streptococcus | 1962 |
Carbohydrate carbonyl mobility--the key process in the formation of alpha-dicarbonyl intermediates.
Topics: Carbohydrate Sequence; Chromatography, High Pressure Liquid; Cross-Linking Reagents; Glucose-6-Phosphate; Glycation End Products, Advanced; Hexoses; Lactose; Lysine; Magnetic Resonance Spectroscopy; Maillard Reaction; Mannose; Mass Spectrometry; Molecular Structure; Phenylenediamines; Quantum Theory; Quinoxalines; Spectrometry, Mass, Electrospray Ionization; Tetroses | 2004 |
Development of 99mTc-neomannosyl human serum albumin (99mTc-MSA) as a novel receptor binding agent for sentinel lymph node imaging.
Topics: Animals; Antimony; Humans; Isothiocyanates; Lymph Nodes; Lysine; Male; Mannose; Mercaptoethanol; Mice; Models, Chemical; Pentetic Acid; Polymers; Protein Binding; Radiochemistry; Rats; Rats, Sprague-Dawley; Sentinel Lymph Node Biopsy; Technetium Compounds; Technetium Tc 99m Aggregated Albumin; Technetium Tc 99m Medronate; Temperature; Thiocyanates; Time Factors; Tin Compounds; Tissue Distribution | 2004 |
Identification of the minimal lysosomal enzyme recognition domain in cathepsin D.
Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; Cathepsin D; Chlorocebus aethiops; Consensus Sequence; COS Cells; HeLa Cells; Humans; Lysine; Lysosomes; Mannose; Mannosephosphates; Molecular Sequence Data; Oligosaccharides; Phosphorylation; Polysaccharides; Precipitin Tests; Protein Structure, Tertiary; Sequence Homology, Amino Acid; Sulfur Radioisotopes; Transferases (Other Substituted Phosphate Groups); Tritium | 2005 |
Design of peptide nucleic acid by introduction of carbohydrate on lysine linker.
Topics: Lysine; Mannose; Nucleic Acid Denaturation; Peptide Nucleic Acids | 2007 |
Mannosylated self-assembled structures for molecular confinement and gene delivery applications.
Topics: Animals; Chlorocebus aethiops; COS Cells; Gene Transfer Techniques; Genes, Reporter; Genetic Therapy; Green Fluorescent Proteins; Liposomes; Lysine; Mannose; Mannosides; Plasmids; Sonication | 2009 |
Eucommia ulmoides extracts prevent the formation of advanced glycation end products.
Topics: Arginine; Eucommiaceae; Flavonoids; Fructose; Galactose; Gelatin; Glucose; Glycation End Products, Advanced; Glycosides; Lysine; Mannose; Plant Extracts; Ribose; Tandem Mass Spectrometry | 2016 |
Topics: Antigens, Neoplasm; Antineoplastic Agents; Cancer Vaccines; Cell Culture Techniques; Cytokines; Dendritic Cells; Epitopes; Fluorescent Dyes; Glycopeptides; gp100 Melanoma Antigen; Humans; Lysine; Mannose; Optical Imaging; T-Lymphocytes; Toll-Like Receptor 7; Vaccines, Conjugate; Vaccines, Synthetic | 2020 |
Triangulating evidence from longitudinal and Mendelian randomization studies of metabolomic biomarkers for type 2 diabetes.
Topics: Adult; Aged; Betaine; Biomarkers; Carnitine; Case-Control Studies; Diabetes Mellitus, Type 2; Early Diagnosis; Female; Genetic Predisposition to Disease; Glutamic Acid; Humans; Leucine; Lysine; Male; Mannose; Mendelian Randomization Analysis; Metabolome; Middle Aged; Valine | 2021 |
Bioinspired design of mannose-decorated globular lysine dendrimers promotes diabetic wound healing by orchestrating appropriate macrophage polarization.
Topics: Animals; Dendrimers; Diabetes Mellitus, Experimental; Lysine; Macrophages; Mannose; Mice; Wound Healing | 2022 |