mannose has been researched along with bimosiamose in 14 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 9 (64.29) | 29.6817 |
| 2010's | 5 (35.71) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Berens, KL; Dixon, RA; Dupre, B; Feng, L; Han, R; Hancock, WW; Kahan, BD; Kirken, RA; Langer, R; Li, P; Podder, H; Stepkowski, SM; Wang, M | 1 |
| Romano, SJ | 1 |
| Beeh, KM; Beier, J; Buhl, R; Meyer, M; Wolff, G; Zahlten, R | 1 |
| Jilma, B; Meyer, M; Wolff, G; Zahlten, R | 1 |
| Aydt, E; Bock, D; Dam, TN; Friedrich, M; Kang, S; Ludwig, N; Philipp, S; Sabat, R; Schroeter-Maas, S; Sterry, W; Wolff, G; Wolk, K; Zahlten, R | 1 |
| Aydt, E; Beeh, KM; Beier, J; Beyer, D; Jilma, B; Meyer, M; Wolff, G; Zahlten, R | 1 |
| Aydt, EM; Beyer, D; Bock, D; Busemann, AS; Heinemann, B; Kranich, R; Meyer, M; Schierhorn, K; Schroeter-Maas, S; Wolff, G; Zahlten, R | 1 |
| Beyer, D; Jilma, B; Meyer, M; Vollhardt, K; Woischwill, C; Wolff, G | 1 |
| Beyer, D; Firbas, C; Jilma, B; Leitner, JM; Mayr, FB; Meyer, M; Reiter, RA; Spiel, AO; Wolff, G | 1 |
| Bird, NC; Canovas, D; Paschos, KA | 1 |
| Bock, D; Kirsten, A; Kretschmar, G; Magnussen, H; Meyer-Sabellek, W; Pedersen, F; Watz, H | 1 |
| Armstrong, PC; Chen, YC; Gardiner, E; Howden, BP; Hu, H; Peter, K; Rigby, S; Rivera, J | 1 |
| Beeh, KM; Beier, J; Bock, D; Kirsten, A; Magnussen, H; Meyer, M; Meyer-Sabellek, W; Pedersen, F; Schierhorn, K; Vollhardt, K; Watz, H; Woischwill, C | 1 |
| Gross, NJ | 1 |
2 review(s) available for mannose and bimosiamose
| Article | Year |
|---|---|
Selectin antagonists : therapeutic potential in asthma and COPD.
Topics: Animals; Asthma; Hexanes; Humans; Inflammation; Lewis X Antigen; Mannose; Oligosaccharides; P-Selectin; Pulmonary Disease, Chronic Obstructive; Selectins; Sialyl Lewis X Antigen | 2005 |
The engagement of selectins and their ligands in colorectal cancer liver metastases.
Topics: Carbohydrate Conformation; Carbohydrate Sequence; Colorectal Neoplasms; Hexanes; Humans; Lewis X Antigen; Ligands; Liver Neoplasms; Mannose; Molecular Sequence Data; Molecular Structure; Protein Isoforms; Selectins; Sialyl Lewis X Antigen | 2010 |
8 trial(s) available for mannose and bimosiamose
| Article | Year |
|---|---|
Bimosiamose, an inhaled small-molecule pan-selectin antagonist, attenuates late asthmatic reactions following allergen challenge in mild asthmatics: a randomized, double-blind, placebo-controlled clinical cross-over-trial.
Topics: Administration, Inhalation; Adult; Allergens; Anti-Asthmatic Agents; Asthma; Breath Tests; Bronchial Provocation Tests; Cross-Over Studies; Double-Blind Method; Forced Expiratory Volume; Hexanes; Humans; Leukocyte Count; Lymphocyte Count; Male; Mannose; Methacholine Chloride; Nitric Oxide; Treatment Outcome | 2006 |
Physiochemical properties, safety and pharmacokinetics of bimosiamose disodium after intravenous administration.
Topics: Adult; Area Under Curve; Dermatitis, Contact; Dizziness; Dose-Response Relationship, Drug; Double-Blind Method; Half-Life; Hexanes; Humans; Hydrogen-Ion Concentration; Infusions, Intravenous; Male; Mannose; Metabolic Clearance Rate; Molecular Structure; Solubility | 2005 |
Pan-selectin antagonism improves psoriasis manifestation in mice and man.
Topics: Adult; Animals; Anti-Inflammatory Agents; Cell Adhesion; Cell Line; Cell Proliferation; Disease Models, Animal; Endothelium, Vascular; Epidermis; Female; Hexanes; HL-60 Cells; Humans; Jurkat Cells; Leukocytes; Male; Mannose; Mice; Mice, SCID; Middle Aged; P-Selectin; Pilot Projects; Psoriasis; T-Lymphocytes | 2006 |
Tolerability and pharmacokinetics of inhaled bimosiamose disodium in healthy males.
Topics: Administration, Inhalation; Adult; Cell Adhesion; Hexanes; Humans; Male; Mannose; Middle Aged; Nasopharyngeal Diseases | 2007 |
The pharmacokinetics of subcutaneously injected Bimosiamose disodium in healthy male volunteers.
Topics: Adult; Anti-Inflammatory Agents; Area Under Curve; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Half-Life; Hexanes; Humans; Injections, Subcutaneous; Male; Mannose; Selectins | 2007 |
Effects of the pan-selectin antagonist bimosiamose (TBC1269) in experimental human endotoxemia.
Topics: Adolescent; Adult; Blood Coagulation; Blood Platelets; Cell Adhesion Molecules; Cross-Over Studies; Double-Blind Method; Endotoxemia; Flow Cytometry; Hemodynamics; Hexanes; Humans; Inflammation; Interleukin-6; Leukocytes; Lipopolysaccharides; Male; Mannose; Platelet Membrane Glycoprotein IIb; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Selectins; Thromboplastin; Time Factors; Tumor Necrosis Factor-alpha | 2008 |
Efficacy of the pan-selectin antagonist Bimosiamose on ozone-induced airway inflammation in healthy subjects--a double blind, randomized, placebo-controlled, cross-over clinical trial.
Topics: Adult; Cross-Over Studies; Double-Blind Method; Exercise Test; Female; Hexanes; Humans; Inflammation; Inhalation Exposure; Interleukin-8; Male; Mannose; Matrix Metalloproteinase 9; Middle Aged; Nebulizers and Vaporizers; Neutrophils; Ozone; Respiratory System; Sputum | 2011 |
Inhaled pan-selectin antagonist Bimosiamose attenuates airway inflammation in COPD.
Topics: Administration, Inhalation; Aged; Asthma; Cross-Over Studies; Double-Blind Method; Female; Hexanes; Humans; Interleukin-8; Male; Mannose; Matrix Metalloproteinase 9; Middle Aged; Pulmonary Disease, Chronic Obstructive; Selectins | 2013 |
4 other study(ies) available for mannose and bimosiamose
| Article | Year |
|---|---|
Selectin inhibitor bimosiamose prolongs survival of kidney allografts by reduction in intragraft production of cytokines and chemokines.
Topics: Animals; Chemokines; Cyclosporine; Cytokines; Drug Synergism; Graft Rejection; Graft Survival; Hexanes; Immunosuppressive Agents; Kidney; Kidney Transplantation; Male; Mannose; Rats; Rats, Inbred Strains; Reperfusion Injury; Selectins; Sirolimus | 2004 |
Rational design of novel, potent small molecule pan-selectin antagonists.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Binding, Competitive; Cell Adhesion; Drug Design; E-Selectin; Hexanes; HL-60 Cells; Humans; L-Selectin; Ligands; Mannose; Models, Molecular; P-Selectin; Phenols; Protein Binding; Selectins | 2007 |
Staphylococcal superantigen-like protein 5 induces thrombotic and bleeding complications in vivo: inhibition by an anti-SSL5 antibody and the glycan Bimosiamose.
Topics: Antibodies; Hemorrhage; Hexanes; Humans; Mannose; Staphylococcus aureus; Superantigens; Thrombosis | 2012 |
The COPD pipeline XXII.
Topics: Anti-Inflammatory Agents; Bronchoscopy; Drug Discovery; Hexanes; Humans; Influenza Vaccines; Lung; Mannose; Organ Size; Pulmonary Disease, Chronic Obstructive; RNA, Antisense; Tobacco Use Cessation Devices; Tumor Necrosis Factor-alpha | 2013 |