Page last updated: 2024-08-22

mannose and bimosiamose disodium

mannose has been researched along with bimosiamose disodium in 24 studies

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's5 (20.83)18.2507
2000's19 (79.17)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Dean, RE; Dixon, RA; Harkema, JM; Kogan, TP; Palma-Vargas, JM; Toledo-Pereyra, L1
Ferrara, JJ; Flint, LM; Hart, KK; Keller, VA; Lefer, DJ; Pigott, JD1
Beck, PJ; Bui, H; Dixon, RA; Dupré, B; Hu, X; Kassir, JM; Kogan, TP; McAbee, KL; Scott, IL; Vanderslice, P1
Abraham, WM; Ahmed, A; Beck, PJ; Bjercke, RJ; Botvinnikova, Y; Dixon, RA; Hu, X; Kogan, TP; Lauredo, IT; Revelle, BM; Sabater, JR; Scott, IL; Yeh, ET1
Dixon, RA; Jordan, JA; Ramos-Kelly, JR; Rivera-Chavez, FA; Toledo-Pereyra, LH; Ward, PA1
Berens, KL; Bochner, BS; Davenpeck, KL; Dixon, RA; Dupre, B1
Allen, SJ; Cox, CS; Frederick, J; Sauer, H1
Ackermann, MR; Brogden, KA; Dixon, RA; Gallup, JM; Ramírez-Romero, R1
Dixon, RA; Holevar, M; Jordan, J; Ramos-Kelly, JR; Rivera-Chavez, F; Rohs, T; Toledo-Pereyra, LH; Ward, PA; Yun, E1
Ackermann, MR; Brogden, KA; Caverly, JM; Dixon, RA; Radi, ZA1
Ackermann, MR; Andreasen, CB; Brogden, KA; Caverly, JM; Dixon, RA; Radi, ZA1
Allen, SJ; Cox, CS; Laine, GA; Sauer, HH1
Berens, K; Burne, MJ; Crosson, J; Daniels, F; Issekutz, A; Kasiske, BL; Keane, WF; Nemoto, T; O'Donnell, MP; Rabb, H1
Romano, SJ; Slee, DH1
Ackermann, MR; Brogden, KA; Dixon, RA; Gallup, JM; Radi, ZA1
Bird, M; Blair, E; Bright, H; Foster, MR; Hurle, M; Malhotra, R; Priest, R; Ward, M1
Berens, K; Dixon, R; Gotoh, R; Isobe, M; Ito, H; Nishiwaki, Y; Onai, Y; Suzuki, J; Yoshida, M1
Berens, KL; Biediger, RJ; Dixon, RA; Holland, GW; Vanderslice, P; Woodside, DG1
Avila, PC; Boushey, HA; Fahy, JV; Grundland, H; Liu, J; Wong, H1
Abbitt, KB; Dodd, P; Hellewell, PG; Hicks, AE; Norman, KE; Ridger, VC1
Beauharnois, ME; Lindquist, KC; Marathe, D; Matta, KL; Neelamegham, S; Vanderslice, P; Xia, J1
Deretz, S; Doucet, C; Favreau, F; Hauet, T; Jayle, C; Mauco, G; Milinkevitch, S; Rabb, H; Richer, JP1
López-Neblina, F; Toledo-Pereyra, LH1
Anaya-Prado, R; Jordan, J; Pérez-Gomez, N; Toledo-Pereyra, LH; Walsh, J; Ward, PA1

Reviews

2 review(s) available for mannose and bimosiamose disodium

ArticleYear
Targeting selectins for the treatment of respiratory diseases.
    Current opinion in investigational drugs (London, England : 2000), 2001, Volume: 2, Issue:7

    Topics: Animals; Anti-Asthmatic Agents; Asthma; Biphenyl Compounds; Cell Adhesion; Chemotaxis, Leukocyte; Clinical Trials as Topic; Endothelium, Vascular; Humans; Inflammation; Leukocytes; Ligands; Lung; Mannose; Mannosides; Membrane Glycoproteins; Oligosaccharides; Pulmonary Disease, Chronic Obstructive; Selectins; Sialyl Lewis X Antigen

2001
Development of cell adhesion molecule antagonists as therapeutics for asthma and COPD.
    Pulmonary pharmacology & therapeutics, 2004, Volume: 17, Issue:1

    Topics: Animals; Asthma; Biphenyl Compounds; Cell Adhesion Molecules; Chemistry, Pharmaceutical; Clinical Trials as Topic; Humans; Integrin alpha4beta1; Mannose; Mannosides; Phenylalanine; Pulmonary Disease, Chronic Obstructive; Selectins

2004

Trials

1 trial(s) available for mannose and bimosiamose disodium

ArticleYear
Effect of a single dose of the selectin inhibitor TBC1269 on early and late asthmatic responses.
    Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 2004, Volume: 34, Issue:1

    Topics: Adult; Allergens; Analysis of Variance; Asthma; Biphenyl Compounds; Female; Forced Expiratory Volume; Humans; Infusions, Intravenous; Integrins; Lung; Male; Mannose; Mannosides; Skin Tests; Treatment Failure

2004

Other Studies

21 other study(ies) available for mannose and bimosiamose disodium

ArticleYear
Small-molecule selectin inhibitor protects against liver inflammatory response after ischemia and reperfusion.
    Journal of the American College of Surgeons, 1997, Volume: 185, Issue:4

    Topics: Animals; Antibodies, Monoclonal; Biphenyl Compounds; Disease Models, Animal; Inflammation; Liver; Mannose; Mannosides; Necrosis; Neutrophil Activation; Peroxidase; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Selectins

1997
Age-related differences in response to neutrophil-mediated reperfusion injury in the neonatal piglet heart.
    Surgery, 1998, Volume: 123, Issue:3

    Topics: Animals; Animals, Newborn; Antibodies, Monoclonal; Biphenyl Compounds; CD18 Antigens; Chemotaxis, Leukocyte; Coronary Circulation; Heart Rate; Hemodynamics; L-Selectin; Lewis X Antigen; Mannose; Mannosides; Neutrophils; Reperfusion Injury; Swine

1998
Novel synthetic inhibitors of selectin-mediated cell adhesion: synthesis of 1,6-bis[3-(3-carboxymethylphenyl)-4-(2-alpha-D- mannopyranosyloxy)phenyl]hexane (TBC1269).
    Journal of medicinal chemistry, 1998, Mar-26, Volume: 41, Issue:7

    Topics: Anti-Asthmatic Agents; Asthma; Biphenyl Compounds; Cell Adhesion; HL-60 Cells; Humans; Mannose; Mannosides; Models, Molecular; Selectins

1998
Selectin blockade prevents antigen-induced late bronchial responses and airway hyperresponsiveness in allergic sheep.
    American journal of respiratory and critical care medicine, 1999, Volume: 159, Issue:4 Pt 1

    Topics: Aerosols; Allergens; Animals; Anti-Inflammatory Agents; Antibodies, Monoclonal; Antigens, Helminth; Ascaris suum; Biphenyl Compounds; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; L-Selectin; Mannose; Mannosides; Phenyl Ethers; Propionates; Respiratory Hypersensitivity; Sheep

1999
Upregulation of lung chemokines associated with hemorrhage is reversed with a small molecule multiple selectin inhibitor.
    Journal of the American College of Surgeons, 1999, Volume: 189, Issue:6

    Topics: Animals; Biphenyl Compounds; Down-Regulation; Lung; Male; Mannose; Mannosides; Neutrophils; Peroxidase; Rats; Rats, Sprague-Dawley; Selectins; Shock, Hemorrhagic; Up-Regulation

1999
Inhibition of adhesion of human neutrophils and eosinophils to P-selectin by the sialyl Lewis antagonist TBC1269: preferential activity against neutrophil adhesion in vitro.
    The Journal of allergy and clinical immunology, 2000, Volume: 105, Issue:4

    Topics: Anti-Asthmatic Agents; Biphenyl Compounds; Cell Adhesion; Eosinophils; Humans; Lewis Blood Group Antigens; Mannose; Mannosides; Neutrophils; Oligosaccharides; P-Selectin; Sialyl Lewis X Antigen

2000
Effects of selectin-sialyl Lewis blockade on mesenteric microvascular permeability associated with cardiopulmonary bypass.
    The Journal of thoracic and cardiovascular surgery, 2000, Volume: 119, Issue:6

    Topics: Animals; Biphenyl Compounds; Capillary Permeability; Cardiopulmonary Bypass; Dogs; Female; Lewis Blood Group Antigens; Lewis X Antigen; Male; Mannose; Mannosides; Microcirculation; Sialyl Lewis X Antigen

2000
Reduction of pulmonary mast cells in areas of acute inflammation in calves with Mannheimia (Pasteurella) haemolytica pneumonia.
    Journal of comparative pathology, 2000, Volume: 123, Issue:1

    Topics: Acute Disease; Animals; Biphenyl Compounds; Cattle; Cell Count; Fluorescent Antibody Technique, Direct; Lung; Male; Mannheimia haemolytica; Mannose; Mannosides; Mast Cells; Pasteurellosis, Pneumonic

2000
Multiple selectin blockade with a small molecule inhibitor downregulates liver chemokine expression and neutrophil infiltration after hemorrhagic shock.
    The Journal of trauma, 2000, Volume: 49, Issue:1

    Topics: Analysis of Variance; Animals; Biphenyl Compounds; Blotting, Northern; Chemokines; Disease Models, Animal; Down-Regulation; Liver; Male; Mannose; Mannosides; Neutrophils; Peroxidase; Rats; Rats, Sprague-Dawley; RNA, Messenger; Selectins; Shock, Hemorrhagic

2000
Effects of the synthetic selectin inhibitor TBC1269 on tissue damage during acute Mannheimia haemolytica-induced pneumonia in neonatal calves.
    American journal of veterinary research, 2001, Volume: 62, Issue:1

    Topics: Animals; Animals, Newborn; Apoptosis; Biphenyl Compounds; Cattle; Epithelial Cells; Leukocytes; Lung; Macrophages; Mannose; Mannosides; Neutrophils; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Pasteurellaceae; Pasteurellosis, Pneumonic; Selectins

2001
Comparison of bronchoalveolar lavage fluid obtained from Mannheimia haemolytica-inoculated calves with and without prior treatment with the selectin inhibitor TBC1269.
    American journal of veterinary research, 2001, Volume: 62, Issue:5

    Topics: Animals; Animals, Newborn; Anti-Asthmatic Agents; Biphenyl Compounds; Bronchoalveolar Lavage Fluid; Cattle; Cattle Diseases; Cell Adhesion; Male; Mannheimia haemolytica; Mannose; Mannosides; Neutrophils; Pasteurella Infections; Peptides; Pneumonia, Bacterial

2001
Effect of sialyl Lewis(x) selectin blockade on myocardial protection during cardioplegic arrest and reperfusion.
    The heart surgery forum, 2001, Volume: 4, Issue:3

    Topics: Animals; Biphenyl Compounds; Cardiopulmonary Bypass; Dogs; Drug Evaluation; Heart Arrest, Induced; Mannose; Mannosides; Myocardial Reperfusion Injury; Neutrophil Activation; Oligosaccharides; Selectins; Sialyl Lewis X Antigen

2001
Small molecule selectin ligand inhibition improves outcome in ischemic acute renal failure.
    Kidney international, 2001, Volume: 60, Issue:6

    Topics: Acute Kidney Injury; Animals; Antibodies; Biphenyl Compounds; CD4 Lymphocyte Count; E-Selectin; Immunohistochemistry; Ischemia; Kidney; Kidney Tubules; Male; Mannose; Mannosides; P-Selectin; Peroxidase; Rats; Rats, Sprague-Dawley; Renal Circulation; Selectins

2001
A selectin inhibitor decreases neutrophil infiltration during acute Mannheimia haemolytica pneumonia.
    Veterinary pathology, 2002, Volume: 39, Issue:6

    Topics: Animals; Animals, Newborn; Biphenyl Compounds; Cattle; Cattle Diseases; Image Processing, Computer-Assisted; In Situ Hybridization; Intercellular Adhesion Molecule-1; Lung; Mannheimia haemolytica; Mannose; Mannosides; Neutrophil Infiltration; Pasteurellaceae Infections; Pneumonia, Bacterial; Selectins

2002
Isolation and characterisation of potential respiratory syncytial virus receptor(s) on epithelial cells.
    Microbes and infection, 2003, Volume: 5, Issue:2

    Topics: Animals; Annexin A2; Biphenyl Compounds; Cell Line; Epithelial Cells; Humans; L-Selectin; Mannose; Mannosides; Mice; Mice, Inbred BALB C; Polysaccharides; Receptors, Virus; Respiratory Syncytial Virus Infections; Respiratory Syncytial Virus, Human; Viral Proteins

2003
Blockade of cell adhesion by a small molecule selectin antagonist attenuates myocardial ischemia/reperfusion injury.
    European journal of pharmacology, 2003, Nov-28, Volume: 481, Issue:2-3

    Topics: Animals; Biphenyl Compounds; Cells, Cultured; HL-60 Cells; Humans; Male; Mannose; Mannosides; Myocardial Ischemia; Myocardial Reperfusion Injury; Neutrophils; Rats; Rats, Sprague-Dawley; Selectins

2003
The anti-inflammatory effects of a selectin ligand mimetic, TBC-1269, are not a result of competitive inhibition of leukocyte rolling in vivo.
    Journal of leukocyte biology, 2005, Volume: 77, Issue:1

    Topics: Animals; Binding, Competitive; Biphenyl Compounds; E-Selectin; Inflammation; Leukocytes; Ligands; Male; Mannose; Mannosides; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Knockout; Molecular Mimicry; Neutrophils; P-Selectin; Peptoids; Peritonitis; Thioglycolates; Venules

2005
Affinity and kinetics of sialyl Lewis-X and core-2 based oligosaccharides binding to L- and P-selectin.
    Biochemistry, 2005, Jul-12, Volume: 44, Issue:27

    Topics: Animals; Binding, Competitive; Biphenyl Compounds; Carbohydrate Sequence; Cell Aggregation; CHO Cells; Cricetinae; Humans; Kinetics; L-Selectin; Lewis Blood Group Antigens; Ligands; Mannose; Mannosides; Molecular Sequence Data; N-Acetylglucosaminyltransferases; Neutrophils; Oligosaccharides; P-Selectin; Protein Binding; Recombinant Fusion Proteins; Rheology; Sialyl Lewis X Antigen; Surface Plasmon Resonance; Trisaccharides

2005
Protective role of selectin ligand inhibition in a large animal model of kidney ischemia-reperfusion injury.
    Kidney international, 2006, Volume: 69, Issue:10

    Topics: Animals; Biphenyl Compounds; Disease Models, Animal; Fibrosis; Immunohistochemistry; Kidney; Ligands; Male; Mannose; Mannosides; Molecular Structure; Nephritis, Interstitial; Protective Agents; Reperfusion Injury; Selectins; Swine; T-Lymphocytes

2006
Anti-ischemic effect of selectin blocker through modulation of tumor necrosis factor-alpha and interleukin-10.
    The Journal of surgical research, 2007, Volume: 138, Issue:2

    Topics: Animals; Biphenyl Compounds; Disease Models, Animal; Dose-Response Relationship, Drug; Interleukin-10; Liver; Male; Mannose; Mannosides; Mice; Mice, Inbred C57BL; Reperfusion Injury; Selectins; Tumor Necrosis Factor-alpha

2007
Small molecule selectin inhibitor in global cerebral ischemia and controlled hemorrhagic shock.
    The Journal of trauma, 2008, Volume: 65, Issue:3

    Topics: Animals; Biphenyl Compounds; Brain Ischemia; Cell Adhesion Molecules; Disease Models, Animal; Male; Mannose; Mannosides; Neutrophil Infiltration; Peroxidase; Rats; Rats, Sprague-Dawley; Shock, Hemorrhagic

2008