Page last updated: 2024-08-22

mannose and 2-methylpentane

mannose has been researched along with 2-methylpentane in 15 studies

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's9 (60.00)29.6817
2010's6 (40.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Berens, KL; Dixon, RA; Dupre, B; Feng, L; Han, R; Hancock, WW; Kahan, BD; Kirken, RA; Langer, R; Li, P; Podder, H; Stepkowski, SM; Wang, M1
Romano, SJ1
Beeh, KM; Beier, J; Buhl, R; Meyer, M; Wolff, G; Zahlten, R1
Jilma, B; Meyer, M; Wolff, G; Zahlten, R1
Aydt, E; Bock, D; Dam, TN; Friedrich, M; Kang, S; Ludwig, N; Philipp, S; Sabat, R; Schroeter-Maas, S; Sterry, W; Wolff, G; Wolk, K; Zahlten, R1
Aydt, E; Beeh, KM; Beier, J; Beyer, D; Jilma, B; Meyer, M; Wolff, G; Zahlten, R1
Aydt, EM; Beyer, D; Bock, D; Busemann, AS; Heinemann, B; Kranich, R; Meyer, M; Schierhorn, K; Schroeter-Maas, S; Wolff, G; Zahlten, R1
Beyer, D; Jilma, B; Meyer, M; Vollhardt, K; Woischwill, C; Wolff, G1
Beyer, D; Firbas, C; Jilma, B; Leitner, JM; Mayr, FB; Meyer, M; Reiter, RA; Spiel, AO; Wolff, G1
Bird, NC; Canovas, D; Paschos, KA1
Bock, D; Kirsten, A; Kretschmar, G; Magnussen, H; Meyer-Sabellek, W; Pedersen, F; Watz, H1
Armstrong, PC; Chen, YC; Gardiner, E; Howden, BP; Hu, H; Peter, K; Rigby, S; Rivera, J1
Beeh, KM; Beier, J; Bock, D; Kirsten, A; Magnussen, H; Meyer, M; Meyer-Sabellek, W; Pedersen, F; Schierhorn, K; Vollhardt, K; Watz, H; Woischwill, C1
Gross, NJ1
Boggiatto, PM; Goodman, JT; Hostetter, JM; Narasimhan, B; Pohl, NL; Roychoudhury, R; Vela-Ramirez, JE; Wannemuehler, MJ1

Reviews

2 review(s) available for mannose and 2-methylpentane

ArticleYear
Selectin antagonists : therapeutic potential in asthma and COPD.
    Treatments in respiratory medicine, 2005, Volume: 4, Issue:2

    Topics: Animals; Asthma; Hexanes; Humans; Inflammation; Lewis X Antigen; Mannose; Oligosaccharides; P-Selectin; Pulmonary Disease, Chronic Obstructive; Selectins; Sialyl Lewis X Antigen

2005
The engagement of selectins and their ligands in colorectal cancer liver metastases.
    Journal of cellular and molecular medicine, 2010, Volume: 14, Issue:1-2

    Topics: Carbohydrate Conformation; Carbohydrate Sequence; Colorectal Neoplasms; Hexanes; Humans; Lewis X Antigen; Ligands; Liver Neoplasms; Mannose; Molecular Sequence Data; Molecular Structure; Protein Isoforms; Selectins; Sialyl Lewis X Antigen

2010

Trials

8 trial(s) available for mannose and 2-methylpentane

ArticleYear
Bimosiamose, an inhaled small-molecule pan-selectin antagonist, attenuates late asthmatic reactions following allergen challenge in mild asthmatics: a randomized, double-blind, placebo-controlled clinical cross-over-trial.
    Pulmonary pharmacology & therapeutics, 2006, Volume: 19, Issue:4

    Topics: Administration, Inhalation; Adult; Allergens; Anti-Asthmatic Agents; Asthma; Breath Tests; Bronchial Provocation Tests; Cross-Over Studies; Double-Blind Method; Forced Expiratory Volume; Hexanes; Humans; Leukocyte Count; Lymphocyte Count; Male; Mannose; Methacholine Chloride; Nitric Oxide; Treatment Outcome

2006
Physiochemical properties, safety and pharmacokinetics of bimosiamose disodium after intravenous administration.
    International journal of clinical pharmacology and therapeutics, 2005, Volume: 43, Issue:10

    Topics: Adult; Area Under Curve; Dermatitis, Contact; Dizziness; Dose-Response Relationship, Drug; Double-Blind Method; Half-Life; Hexanes; Humans; Hydrogen-Ion Concentration; Infusions, Intravenous; Male; Mannose; Metabolic Clearance Rate; Molecular Structure; Solubility

2005
Pan-selectin antagonism improves psoriasis manifestation in mice and man.
    Archives of dermatological research, 2006, Volume: 297, Issue:8

    Topics: Adult; Animals; Anti-Inflammatory Agents; Cell Adhesion; Cell Line; Cell Proliferation; Disease Models, Animal; Endothelium, Vascular; Epidermis; Female; Hexanes; HL-60 Cells; Humans; Jurkat Cells; Leukocytes; Male; Mannose; Mice; Mice, SCID; Middle Aged; P-Selectin; Pilot Projects; Psoriasis; T-Lymphocytes

2006
Tolerability and pharmacokinetics of inhaled bimosiamose disodium in healthy males.
    British journal of clinical pharmacology, 2007, Volume: 63, Issue:4

    Topics: Administration, Inhalation; Adult; Cell Adhesion; Hexanes; Humans; Male; Mannose; Middle Aged; Nasopharyngeal Diseases

2007
The pharmacokinetics of subcutaneously injected Bimosiamose disodium in healthy male volunteers.
    Biopharmaceutics & drug disposition, 2007, Volume: 28, Issue:9

    Topics: Adult; Anti-Inflammatory Agents; Area Under Curve; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Half-Life; Hexanes; Humans; Injections, Subcutaneous; Male; Mannose; Selectins

2007
Effects of the pan-selectin antagonist bimosiamose (TBC1269) in experimental human endotoxemia.
    Shock (Augusta, Ga.), 2008, Volume: 29, Issue:4

    Topics: Adolescent; Adult; Blood Coagulation; Blood Platelets; Cell Adhesion Molecules; Cross-Over Studies; Double-Blind Method; Endotoxemia; Flow Cytometry; Hemodynamics; Hexanes; Humans; Inflammation; Interleukin-6; Leukocytes; Lipopolysaccharides; Male; Mannose; Platelet Membrane Glycoprotein IIb; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Selectins; Thromboplastin; Time Factors; Tumor Necrosis Factor-alpha

2008
Efficacy of the pan-selectin antagonist Bimosiamose on ozone-induced airway inflammation in healthy subjects--a double blind, randomized, placebo-controlled, cross-over clinical trial.
    Pulmonary pharmacology & therapeutics, 2011, Volume: 24, Issue:5

    Topics: Adult; Cross-Over Studies; Double-Blind Method; Exercise Test; Female; Hexanes; Humans; Inflammation; Inhalation Exposure; Interleukin-8; Male; Mannose; Matrix Metalloproteinase 9; Middle Aged; Nebulizers and Vaporizers; Neutrophils; Ozone; Respiratory System; Sputum

2011
Inhaled pan-selectin antagonist Bimosiamose attenuates airway inflammation in COPD.
    Pulmonary pharmacology & therapeutics, 2013, Volume: 26, Issue:2

    Topics: Administration, Inhalation; Aged; Asthma; Cross-Over Studies; Double-Blind Method; Female; Hexanes; Humans; Interleukin-8; Male; Mannose; Matrix Metalloproteinase 9; Middle Aged; Pulmonary Disease, Chronic Obstructive; Selectins

2013

Other Studies

5 other study(ies) available for mannose and 2-methylpentane

ArticleYear
Selectin inhibitor bimosiamose prolongs survival of kidney allografts by reduction in intragraft production of cytokines and chemokines.
    Journal of the American Society of Nephrology : JASN, 2004, Volume: 15, Issue:11

    Topics: Animals; Chemokines; Cyclosporine; Cytokines; Drug Synergism; Graft Rejection; Graft Survival; Hexanes; Immunosuppressive Agents; Kidney; Kidney Transplantation; Male; Mannose; Rats; Rats, Inbred Strains; Reperfusion Injury; Selectins; Sirolimus

2004
Rational design of novel, potent small molecule pan-selectin antagonists.
    Journal of medicinal chemistry, 2007, Mar-22, Volume: 50, Issue:6

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Binding, Competitive; Cell Adhesion; Drug Design; E-Selectin; Hexanes; HL-60 Cells; Humans; L-Selectin; Ligands; Mannose; Models, Molecular; P-Selectin; Phenols; Protein Binding; Selectins

2007
Staphylococcal superantigen-like protein 5 induces thrombotic and bleeding complications in vivo: inhibition by an anti-SSL5 antibody and the glycan Bimosiamose.
    Journal of thrombosis and haemostasis : JTH, 2012, Volume: 10, Issue:12

    Topics: Antibodies; Hemorrhage; Hexanes; Humans; Mannose; Staphylococcus aureus; Superantigens; Thrombosis

2012
The COPD pipeline XXII.
    COPD, 2013, Volume: 10, Issue:3

    Topics: Anti-Inflammatory Agents; Bronchoscopy; Drug Discovery; Hexanes; Humans; Influenza Vaccines; Lung; Mannose; Organ Size; Pulmonary Disease, Chronic Obstructive; RNA, Antisense; Tobacco Use Cessation Devices; Tumor Necrosis Factor-alpha

2013
Safety and biocompatibility of carbohydrate-functionalized polyanhydride nanoparticles.
    The AAPS journal, 2015, Volume: 17, Issue:1

    Topics: Administration, Intranasal; Animals; Bronchoalveolar Lavage Fluid; Carbohydrates; Chemokines; Cytokines; Female; Galactose; Glycolates; Hexanes; Injections; Kidney; Lectins, C-Type; Liver; Lung; Mannose; Mice; Nanoparticles; Polyanhydrides; Polyethylene Glycols

2015