mannitol has been researched along with metoprolol in 24 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (4.17) | 18.7374 |
| 1990's | 1 (4.17) | 18.2507 |
| 2000's | 13 (54.17) | 29.6817 |
| 2010's | 9 (37.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ghuloum, AM; Jain, AN; Sage, CR | 1 |
| Danelian, E; Hämäläinen, MD; Hansson, A; Karlén, A; Karlsson, R; Lennernäs, H; Löfâs, S; Winiwarter, S | 1 |
| Ertl, P; Rohde, B; Selzer, P | 1 |
| Artursson, P; Luthman, K; Norinder, U; Stenberg, P | 1 |
| Hwang, KK; Mandagere, AK; Thompson, TN | 1 |
| Artursson, P; Bergström, CA; Matsson, P; Nagahara, N; Norinder, U; Tavelin, S | 1 |
| Caron, G; Ermondi, G | 1 |
| Baert, B; Beetens, J; Bodé, S; De Spiegeleer, B; Deconinck, E; Lambert, J; Slegers, G; Slodicka, M; Stoppie, P; Van Gele, M; Vander Heyden, Y | 1 |
| Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Campillo, NE; Guerra, A; Páez, JA | 1 |
| Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K | 1 |
| Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V | 1 |
| Barber, S; Dew, TP; Farrell, TL; Poquet, L; Williamson, G | 1 |
| Chien, C; Colonno, RJ; D'Arienzo, C; Eggers, B; Gao, Q; Gong, YF; Grasela, DM; Kadow, JF; Langley, DR; Lin, PF; Malinowski, J; Mathew, M; Meanwell, NA; Parker, DD; Regueiro-Ren, A; Sun, Y; Swidorski, JJ; Wu, D; Xue, QM; Yang, Z; Zheng, M | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Mikulecký, M; Pechán, J; Srbecký, M | 1 |
| Amidon, GL; Hilgendorf, C; Langguth, P; Lipka, E; Regårdh, CG; Spahn-Langguth, H | 1 |
| Hayashi, J; Lentz, KA; Lucisano, LJ; Polli, JE | 1 |
| Eskola, S; Forbes, B; Murray, J; Patel, N | 1 |
| Kao, JP; Polli, JE; Seo, PR; Teksin, ZS | 1 |
| Holm, R; Hyrup, B; Jacobsen, J; Marxen, E; Meng-Lund, E; Müllertz, A; Pedersen, AML | 1 |
| Birch, D; Christophersen, PC; Diedrichsen, RG; Mu, H; Nielsen, HM | 1 |
1 review(s) available for mannitol and metoprolol
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
23 other study(ies) available for mannitol and metoprolol
| Article | Year |
|---|---|
Molecular hashkeys: a novel method for molecular characterization and its application for predicting important pharmaceutical properties of molecules.
Topics: Drug Design; Intestinal Absorption; Models, Molecular; Pharmaceutical Preparations; Structure-Activity Relationship | 1999 |
SPR biosensor studies of the direct interaction between 27 drugs and a liposome surface: correlation with fraction absorbed in humans.
Topics: Humans; Intestinal Absorption; Liposomes; Pharmaceutical Preparations; Pharmacokinetics; Predictive Value of Tests; Surface Plasmon Resonance | 2000 |
Fast calculation of molecular polar surface area as a sum of fragment-based contributions and its application to the prediction of drug transport properties.
Topics: Biological Availability; Biological Transport; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Reproducibility of Results | 2000 |
Experimental and computational screening models for the prediction of intestinal drug absorption.
Topics: Biological Transport; Carbon Radioisotopes; Cell Line; Cell Membrane; Cell Membrane Permeability; Ciprofloxacin; Computational Biology; Drug Design; Foscarnet; Humans; Hydrogen Bonding; Intestinal Absorption; Intestinal Mucosa; Lactulose; Mannitol; Models, Biological; Raffinose; Surface Properties; Tritium; Verapamil | 2001 |
Graphical model for estimating oral bioavailability of drugs in humans and other species from their Caco-2 permeability and in vitro liver enzyme metabolic stability rates.
Topics: Administration, Oral; Animals; Biological Availability; Caco-2 Cells; Dogs; Guinea Pigs; Humans; In Vitro Techniques; Inactivation, Metabolic; Liver; Microsomes, Liver; Models, Biological; Permeability; Pharmacokinetics; Rats; Species Specificity | 2002 |
Exploring the role of different drug transport routes in permeability screening.
Topics: Administration, Oral; Biological Transport; Caco-2 Cells; Cell Line; Humans; Intestinal Absorption; Intestinal Mucosa; Intestine, Small; Membranes, Artificial; Models, Biological; Molecular Conformation; Monte Carlo Method; Permeability; Pharmaceutical Preparations; Pharmacokinetics | 2005 |
Calculating virtual log P in the alkane/water system (log P(N)(alk)) and its derived parameters deltalog P(N)(oct-alk) and log D(pH)(alk).
Topics: 1-Octanol; Alkanes; Hydrogen-Ion Concentration; Least-Squares Analysis; Mathematics; Models, Chemical; Models, Molecular; Solvents; Water | 2005 |
Transdermal penetration behaviour of drugs: CART-clustering, QSPR and selection of model compounds.
Topics: Anti-Inflammatory Agents; Cell Membrane Permeability; Cluster Analysis; Drug Evaluation, Preclinical; Humans; Models, Biological; Predictive Value of Tests; Quantitative Structure-Activity Relationship; Regression Analysis; Skin; Skin Absorption | 2007 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain.
Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical | 2010 |
QSAR-based permeability model for drug-like compounds.
Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2011 |
FDA-approved drug labeling for the study of drug-induced liver injury.
Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration | 2011 |
Predicting phenolic acid absorption in Caco-2 cells: a theoretical permeability model and mechanistic study.
Topics: Artificial Intelligence; Caco-2 Cells; Cell Membrane Permeability; Cinnamates; Enterocytes; Humans; Hydrophobic and Hydrophilic Interactions; Intestinal Absorption; Kinetics; Models, Biological; Molecular Conformation; Osmolar Concentration; Phenols | 2012 |
Inhibitors of human immunodeficiency virus type 1 (HIV-1) attachment. 12. Structure-activity relationships associated with 4-fluoro-6-azaindole derivatives leading to the identification of 1-(4-benzoylpiperazin-1-yl)-2-(4-fluoro-7-[1,2,3]triazol-1-yl-1h-p
Topics: Animals; Anti-HIV Agents; Caco-2 Cells; Cell Membrane Permeability; Crystallography, X-Ray; HIV-1; Humans; Indoles; Microsomes, Liver; Piperazines; Pyridines; Pyrroles; Quantum Theory; Rats; Structure-Activity Relationship; Triazines; Triazoles; Virus Attachment | 2013 |
Acute haemodynamic effect of metoprolol in essential hypertension.
Topics: Adolescent; Adult; Blood Pressure; Cardiac Output; Female; Forearm; Heart Rate; Hemodynamics; Humans; Hypertension; Infusions, Intravenous; Injections, Intravenous; Male; Mannitol; Metoprolol; Middle Aged; Regional Blood Flow; Vascular Resistance | 1988 |
Caco-2 versus Caco-2/HT29-MTX co-cultured cell lines: permeabilities via diffusion, inside- and outside-directed carrier-mediated transport.
Topics: Antipyrine; Atenolol; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport, Active; Caco-2 Cells; Carrier Proteins; Cell Membrane Permeability; Cellular Senescence; Coculture Techniques; Furosemide; HT29 Cells; Humans; Intestinal Absorption; Intestinal Mucosa; Ketoprofen; Mannitol; Metoprolol; Microscopy, Electron; Piroxicam; Reproducibility of Results; Terbutaline | 2000 |
Development of a more rapid, reduced serum culture system for Caco-2 monolayers and application to the biopharmaceutics classification system.
Topics: Adrenergic beta-Antagonists; Alkaline Phosphatase; Animals; Biomarkers; Biopharmaceutics; Caco-2 Cells; Cattle; Cell Division; Cell Membrane Permeability; Cholagogues and Choleretics; Culture Media; Cytological Techniques; Diuretics, Osmotic; Humans; Hydrogen-Ion Concentration; Mannitol; Metoprolol; Microscopy, Electron; Taurocholic Acid | 2000 |
Use of simulated intestinal fluids with Caco-2 cells and rat ileum.
Topics: Animals; Bile Acids and Salts; Caco-2 Cells; Humans; Hydrogen-Ion Concentration; Ileum; In Vitro Techniques; Intestinal Absorption; Male; Mannitol; Metoprolol; Permeability; Rats; Rats, Sprague-Dawley | 2006 |
Lipid composition effect on permeability across PAMPA.
Topics: Anisotropy; Benzoic Acid; Cell Membrane Permeability; Hydrogen-Ion Concentration; Mannitol; Membrane Lipids; Membranes, Artificial; Metoprolol; Sucrose; Taurocholic Acid | 2006 |
Ex vivo correlation of the permeability of metoprolol across human and porcine buccal mucosa.
Topics: Adolescent; Adrenergic beta-1 Receptor Antagonists; Adult; Animals; Biological Transport; Data Interpretation, Statistical; Female; Humans; Hydrogen-Ion Concentration; In Vitro Techniques; Male; Mannitol; Metoprolol; Mouth Mucosa; Oral Mucosal Absorption; Permeability; Species Specificity; Sus scrofa; Time Factors; Young Adult | 2014 |
Evaluation of drug permeation under fed state conditions using mucus-covered Caco-2 cell epithelium.
Topics: Caco-2 Cells; Cell Survival; Coculture Techniques; Cyclosporine; Deamino Arginine Vasopressin; Fenofibrate; HT29 Cells; Humans; Intestinal Absorption; Intestinal Mucosa; Mannitol; Metoprolol; Models, Biological; Mucus; Ovalbumin; Permeability | 2018 |